Enzyme activity and protein of multiple forms of choline acetyltransferase: Effects of calyculin A and okadaic acid

Neurochemical Research

Volumn 24, Issue 8, 1999, Pages 987-993

  Issa, Amalia M ^a   Gauthier, Serge ^a   Collier, Brian ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Calyculin A; Choline acetyltransferase; Immunoreactive choline acetyltransferase; Okadaic acid; Phosphatases

Indexed keywords

CALYCULIN A; CHOLINE ACETYLTRANSFERASE; ISOENZYME; OKADAIC ACID;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME ISOLATION; ENZYME LOCALIZATION; ENZYME POLYMORPHISM; ENZYME REPRESSION; MALE; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CHOLINE O-ACETYLTRANSFERASE; ENZYME INHIBITORS; HIPPOCAMPUS; ISOENZYMES; MALE; OKADAIC ACID; OXAZOLES; PHOSPHOPROTEIN PHOSPHATASE; RATS; RATS, SPRAGUE-DAWLEY; SUBCELLULAR FRACTIONS;

ANIMALIA;

EID: 0032838832     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021096408174     Document Type: Article

References (38)

1. Benishin, C. G., and Carroll, P. T. 1981. Acetylation of choline and homocholine by membrane-bound choline-O-acetyltransferase in mouse forebrain nerve endings. J. Neurochem. 36:732-740.
2. Benishin, C. G., and Carroll P. T. 1983. Multiple forms of choline-O-acetyltransferase in mouse and rat brain: Solubilization and characterization. J. Neurochem. 41:1030-1039.
3. Eder-Colli, L., and Amato, S. 1985. Membrane-bound choline acetyltransferase in Torpedo electric organ: A marker for synaptosomal plasma membranes? Neurosci. 15:577-589.
4. Rylett, R. J. 1989. Synapstosomal 'membrane-bound' choline acetyltransferase is most sensitive to inhibition by choline mustard. J. Neurochem. 52:869-872.
5. Schmidt, B. M., and Rylett, R. J. 1993. Phosphorylation of rat brain choline acetyltransferase and its relationship to enzyme activity. J. Neurochem. 61:1774-1781.
6. Schmidt, B. M., and Rylett R. J. 1993. Basal synthesis of acetylcholine in rat hippocampal synaptosomes is not regulated by membrane-bound choline acetyltransferase. Neurosci. 54: 649-656.
7. Salem, N., Medilanski, J., Pellegrinelli, N., and Eder-Colli, L. 1993. The proportion of amphilic choline acetyltransferase in Drosophila melanogaster is higher than in rat or Torpedo and is developmentally regulated. Brain Res. 609:223-230.
8. Carroll, P. T. 1987. Veratridine-induced activation of choline-O-acetyltransferase activity in rat hippocampal tissue: Relationship to the veratridine-induced release of acetylcholine. Brain Res. 414:401-4.
9. Badamchian, M., Morrow, K. J., and Carroll, P. T. 1986. Immunological, isoelectric, hydrophobic and molecular weight differences between soluble and ionically membrane-bound fractions of choline-O-acetyltransferase prepared from mouse and rat brain. Neurochem. Int. 9:409-421.
10. Boksa, P., and Collier, B. 1980. Acetylation of homocholine by rat brain: Subcellular distribution of acetylhomocholine and studies on the ability of homocholine to serve as substrate for choline acetyltransferase in situ and in vitro. J. Neurochem. 34: 1470-1482.
11. Eder-Colli, L., Amato, S., and Fromont, Y. 1986. Amphilic and hydrophilic forms of choline-O-acetyltransferase in cholinergic nerve endings of the Torpedo. Neurosci. 19:275-287.
12. Peng, J. H., McGeer, P. L., and McGeer, E. G. 1986. Membrane-bound choline acetyltransferase from human brain: Purification and properties. Neurochem. Res. 11:959-971.
13. Zinman, L. H., Lawrance, G., Wang, W., Verge, V. M. K., Dow, K. E., Maurice, D. H., Richardson, P. M., and Riopelle, R. J. 1998. Collaborative and reciprocal effects of ciliary neurotrophic factor and nerve growth factor on the neuronal phenotype of human neuroblastoma cells. J. Neurochem. 70:1411-1420.
14. Berrard, S., Brice, A., Lottspeich, F., Braun, A., Barde, Y. and Mallet, J. 1987. cDNA cloning and complete sequence of porcine choline acetyltransferase: in vitro translation of the corresponding RNA yields an active protein. Proc. Natl. Acad. Sci. USA 84:9280-9284.
15. Brite, A., Berrard, S., Raynaud, B., Ansieau, S., Coppola, T., Weber, M. J., and Mallet, J. 1989 Complete sequence of a cDNA encoding an active rat choline acetyltransferase: a tool to investigate the plasticity of cholinergic expression. J. Neurosci. Res. 23:266-273.
16. Bruce, G., and Hersh, L. B. 1989. The phosphorylation of choline acetyltransferase. Neurochem. Res. 14:613-620.
17. Habert, E., Birman, S., and Mallet, J. 1992. High-level synthesis and fate of acetylcholine in baculovirus-infected cells: characterization and purification of recombinant rat choline acetyltransferase. J. Neurochem. 58:1447-1453.
18. Issa, A. M., Gauthier, S., and Collier, B. 1996 Effects of the phosphatase inhibitors calyculin A and okadaic acid on acetylcholine synthesis and content of rat hippocampal formation. J. Neurochem. 66:1924-1932.
19. Ostermann-Latif, C., Mäder, M., and Felgenhauer, K. 1993. An efficient sandwich-ELISA for the determination of choline acetyltransferase. J. Immunol. Methods 157:73-79.
20. Fonnum, F. 1969. Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities. Biochem. J. 115:465-472.
21. Tuček, S. 1978. Choline acetyltransferase. Pages 128-164 in: Acetylcholine Synthesis in Neurons, Chapman and Hall Ltd., London.
22. Badamchian, M., and Carroll, P. T. 1985. Molecular weight determination of soluble and membrane - bound fractions of choline-O-acetyltransferase in rat brain. J. Neurosci. 5:1955-1964.
23. Cooke, L. J., and Rylett, R. J. 1997. Inhibitors of serine/threonine phosphatases increase membrane - bound choline acetyltransferase activity and enhance acetylcholine synthesis. Brain Res. 751: 232-238.
24. Smith, C. P., and Carroll, P. T. 1980. A comparison of solubilized and membrane bound for choline-O-acetyltransferase (EC 2.3.1.6) in mouse brain nerve endings. Brain Res. 185:363-372.
25. Ostermann, C., Dickmann, U., Muley, T., and Mäder, M. 1990. Large - scale purification of choline acetyltransferase and production of highly specific antisera. Eur. J. Biochem. 192:215-218.
26. Ryan, R. L., and McClure, W. O. 1979. Purification of choline acetyltransferase from rat and cow brain. Biochemistry 24: 5537-5365.
27. Strauss W. L. and Nirenberg M., 1985. Inhibition of choline acetyltransferase by monoclonal antibodies. J. Neurosci. 1: 175-180.
28. Barford, D. 1991. Molecular mechanisms for the control of enzymic activity by protein phosphorylation. Biochim. Biophys. Acta 1133:55-62.
29. Cohen, P. 1982. The role of protein phosphorylation in neural and hormonal control of cellular activity. Nature 296:613-620.
30. Zigmond, R. E., Schwarzschild, M. A., and Rittenhouse, A. R. 1989. Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation. Ann. Rev. Neurosci. 12:415-461.
31. Mallet, J., Berrard, S., Brice, A., Habert, E., Raynaud, B., Vernier, P., and Weber, M. 1990. Choline acetyltransferase: a molecular genetic approach. Prog. in Brain Res. 84:3-10.
32. + and nerve growth factor. Evidence for different mechanisms of action. Mol. Pharmacol. 28:220-228.
33. McTigue, M., Cremins, J., and Halegoua, S. 1985. Nerve growth factor and other agents mediate phosphorylation and activation of tyrosine hydroxylase. A convergence of multiple kinase activities. J. Biol. Chem. 260:9047-9056.
34. Hefen, E. 1998. Kinases and phosphatases - a marriage is consummated. Science 280:1212-1213.
35. 2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A. Science 280:1258-1261.
36. Pongrac, J. L., and Rylett, R. J. 1996. Differential effects of nerve growth factor on expression of choline acetyltransferase and sodium-coupled coupled transport in basal forebrain cholinergic neurons in culture. J. Neurochem. 66:804-810.
37. Tandon, A., Bachoo, M., Weldon, P., Polosa, C., and Collier B. 1996. Effects of colchicine application to preganglionic axons on choline acetyltransferase activity and acetylcholine content and release in the superior cervical ganglion. J. Neurochem. 66:1033-1041.
38. Wessler, I., Reinheimer, T., Bittniger, F., Kirkpatrick, C. J. Schenda, J., and Vollrath, L. 1997. Day - night rhythym of acetylcholine in the rat pineal gland. Neurosci. Lett. 224:173-176.