Programmed cell death in normal epidermis and loricrin keratoderma. Multiple functions of profilaggrin in keratinization

Journal of Investigative Dermatology Symposium Proceedings

Volumn 4, Issue 2, 1999, Pages 145-149

  Ishida Yamamoto, Akemi ^a   Tanaka, Hikaru ^a   Nakane, Hiroshi ^a   Takahashi, Hidetoshi ^a   Hashimoto, Yoshio ^a   Iizuka, Hajime ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Apoptosis; Transitional cells

Indexed keywords

DNA; KERATIN; LORICRIN; PROFILAGGRIN;

ANIMAL CELL; APOPTOSIS; CONFERENCE PAPER; CYTOLOGY; EPIDERMIS; HUMAN; HUMAN CELL; KERATINIZATION; KERATODERMA; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

EID: 0032834474     PISSN: 10870024     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jidsp.5640198     Document Type: Conference Paper

References (65)

1. Adams JC, Watt FM: Fibronectin inhibits the terminal differentiatin of human keratinocytes. Nature 340:307-309, 1989
2. Armstrong DKB, McKenna KE, Hughes AE: A novel insertional mutation in loricrin in Vohwinkel's keratoderma. J Invest Dermatol 111:702-704, 1998
3. Brody I: The ultrastructure of the tonofibrils in the keratinization process of normal human epidermis. J Ultrastr Res 4:264-297, 1960
4. Cohen JJ, Duke RC: Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol 132:38-42, 1984
5. Dale BA, Holbrook KA, Steinert PM: Assembly of stratum corneum basic protein and keratin filaments in macrofibrils. Nature 276:729-731, 1978
6. Dale BA, Resing KA, Presland RB. Keratohyalin granule proteins. In: Leigh I, Lane B, Watt F (eds). The Keratinocyte Handbook. Cambridge: Cambridge University Press, 1994, pp. 323-350
7. Dale BA, Presland RB, Lewis SP, Underwood RA, Fleckman P: Transient expression of epidermal filaggrin in cultured cells causes collapse of intermediate filament networks with alteration of cell shape and nuclear integrity. J Invest Dermatol 108:179-187, 1997
8. Eckert RL, Crish JF, Robinson NA: The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation. Physiol Rev 77:397-424, 1997
9. Fesus L, Thomazy V, Autuori F, Ceru MP, Tarcsa E, Piacentini M: Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action. FEBS Lett 245:150-154, 1989
10. Fesus L, Davies PJA, Piacentini M: Apoptosis: molecular mechanisms in programmed cell death. Eur J Cell Biol 56:170-177, 1991
11. Frisch SM, Francis H: Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124:619-626, 1994
12. Fuchs E: Epidermal differentiation: the bare essentials. J Cell Biol 111:2807-2814, 1990
13. Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501, 1992
14. Green H: Terminal differentiation of cultured human epidermal cells. Cell 11:405-416, 1977
15. Haake AR, Polakowska RR: Cell death by apoptosis in epidermal biology. J Invest Dermatol 101:107-112,1993
16. Hockenbery DM, Zutter M, Hickey W, Nahm M, Korsmeyer SJ: BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Natl Acad Sci USA 88:6961-6965, 1991
17. Hohl D, Mehrel T, Lichti U, Turner ML, Roop DR, Steinert PM: Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins. J Biol Chem 266:6626-6636, 1991
18. Holbrook KA: Biologic structure and function: perspectives on morphologic approaches to the study of the granular layer keratinocyte. J Invest Dermatol 92:84S-104S, 1989
19. Ishida-Yamamoto A, Iizuka H: Structural organization of cornified cell envelopes and alterations in inherited skin disorders. Exp Dermatol 7:1-10, 1998
20. Ishida-Yamamoto A, Hohl D, Roop DR, Iizuka H, Eady RAJ: Loricrin immunoreactivity in human skin: localization to specific granules (L-granules) in acrosyringia. Arch Dermatol Res 285:491-498, 1993
21. Ishida-Yamamoto A, Eady RAJ, Watt FM, Roop DR, Hohl D, Iizuka H: Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis. J Histochem Cytochem 44:167-175, 1996
22. Ishida-Yamamoto A, McGrath JA, Lam H, Iizuka H, Friedman RA, Christiano AM: The molecular pathology of progressive symmetric erythrokeratoderma: a frameshift mutation in the loricrin gene and perturbations in the cornified cell envelope. Am J Hum Genet 61:581-589, 1997
23. Ishida-Yamamoto A, Takahashi H, Iizuka H: Loricrin and human skin disease: molecular basis of loricrin kratodermas. Histol Histopath 13:819-826, 1998a
24. Ishida-Yamamoto A, Takahashi H, Presland RB, Dale BA, Iizuka H: Translocation of profilaggrin N-terminal domain into keratinocyte nuclei with Fragmented DNA in normal human skin and loricrin keratoderma. Lab Invest 78:1245-1253. 1998b
25. Ishida-Yamamoto A, Tanaka H, Nakane H, Takahashi H, Iizuka H: Inherited disorders of epidermal keratinization. J Dermatol Sci 18:139-154, 1998c
26. Kam E, Resing KA, Lim SK, Dale BA: Identification of rat epidermal profilaggrin phosphatase as a member of the protein phosphatase 2A family. J Cell Sci 106:219-226, 1993
27. Kawada A, Hara K, Hiruma M, Noguchi H, Ishibashi A: Rat epidermal cathepsin L-like proteinase: purification and some hydrolytic properties toward filaggrin and synthetic substrates. J Biochem 118:332-337, 1995a
28. Kawada A, Hara K, Morimoto K, Hiruma M, Ishibashi A: Rat epidermal cathepsin B. purification and characterization of proteolytic properties toward filaggrin and synthetic substrates. Int J Biochem Cell Biol 27:175-183, 1995b
29. Kerr JFR, Wyllie AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257, 1972
30. Korge BP, Ishida-Yamamoto A, Pünter C, Dopping-Hepenstal P, Iizuka H, Stephenson A, Munro CS: Loricrin mutation in Vohwinkel's keratoderma is unique to the variant with ichthyosis. J Invest Dermatol 109:604-610, 1997
31. Krajewska M, Wang H-G, Krajewski S, Zapata JM, Shabaik A, Gascoyne R, Reed JC: Immunohistochemical analysis of in vivo patterns of expression of CPP 32 (caspase-3), a cell death protease. Cancer Res 57:1605-1613, 1997
32. Krajewski S, Krajewska M, Reed JC: Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family. Cancer Res 56:2849-2855, 1996
33. Mack JW, Steven AC, Steinert PM: The mechanism of interaction of filaggrin with intermediate filaments. The ionic zipper hypothesis. J Mol Biol 232:50-66, 1993
34. Maestrini E, Monaco AP, McGrath JA, et al: A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndrome. Nature Genet 13:70-77, 1996
35. Manabe M, Mizoguchi M, Suto H, Ogawa H: Epidermal structural proteins in skin disorders. J Dermatol Sci 15:143-165, 1997
36. Markova NG, Marekov LN, Chipev CC, Can S-Q, Idler WW, Steinert PM: Profilaggrin is a major epidermal calcium-binding protein. Mol Cell Biol 13:613-625, 1993
37. Marthinuss J, Lawrence L, Seiberg M: Apoptosis in Pam212, an epidermal keratinocyte cell line: a possible role for bcl-2 in epidermal differentiation. Cell Growth Differ 6:239-250, 1995
38. McCall CA, Cohen JJ: Programmed cell death in terminally differentiating keratinocytes: role of endogeneous endonuclease. J Invest Dermatol 97:111-114, 1991
39. Mehrel T, Hohl D, Rothnagel JA, et al: Identification of a major keratinocyte cell envelope protein, loricrin. Cell 61:1103-1112, 1990
40. Nicholson DW, Thornberry NA: Caspases: killer proteases. TIBS 22:299-306, 1997
41. Polakowska RR, Piacentini M, Bartlett R, Goldsmith LA, Haake AR: Apoptosis in human skin development: morphogenesis, periderm, and stem cells. Dev Dynam 199:176-188, 1994
42. Presland RB, Haydock PV, Fleckman P, Nirunsuksiri W, Dale BA: Characterization of the human epidermal profilaggrin gene. Genomic organization and identification of an S-100-like calcium binding domain at the amino terminus. J Biol Chem 267:23772-23781, 1992
43. Presland RB, Bassuk JA, Kimball JR, Dale BA: Characterization of two distinct calcium-binding sites in the amino-terminus of human profilaggrin. J Invest Dermatol 104:218-223, 1995
44. Presland RB, Kimbail JR, Kautsky MB, Lewis SP, Lo CY, Dale BA: Evidence for specific proteolytic cleavage of the N-terminal domain of human profilaggrin during epidermal differentiation. J Invest Dermatol 108:170-178, 1997
45. Resing KA, Walsh KA, Haugen-Scofield J, Dale BA: Identification of proteolytic cleavage sites in the conversion of profilaggrin to filaggrin in mammalian epidermis. J Biol Chem 264:1837-1845, 1989
46. 2+ in the second stage. J Biol Chem 268:25139-25145, 1993
47. Resing KA, Johnson RS, Walsh KA: Mass spectrometric analysis of 21 phosphorylation sites in the internal repeat of rat profilaggrin, precursor of an intermediate filament associated protein. Biochem 34:9477-9478, 1995a
48. Resing KA, Thulin C, Whiting K, Al-Alawi N, Mostad S: Characterization of profilaggrin endoproteinase I. A regulated cytoplasmic endoproteinase of epidermis. J Biol Chem 270:28193-28198, 1995b
49. Roop D: Defects in the barrier. Science 267:474-475, 1995
50. 2+-calmodulin and caspase-dependent pathway. J Invest Dermatol 111:64-71, 1998
51. Ruoslahti E, Reed JC: Anchorage dependence, integrins, and apoptosis. Cell 77:477-478, 1994
52. Scott IR, Harding CR, Barrett JG: Histidine-rich protein of the keratohyalin granules. Source of the free amino acids, urocanic acid and pyrrolidone carboxylic acid in the stratum corneum. Biochim Biophys Acta 719:110-117, 1982
53. Senshu T, Kan S, Ogawa H, Manabe M, Asaga H: Preferential deimination of keratin K1 and filaggrin during the terminal differentiation of human epidermis. Biochem Biophys Res Comm 225:712-719, 1996
54. Steigleder GK, Raab WP: The localization of ribonuclease and deoxyribonuclease activities in normal and psoriatic epidermis. J Invest Dermatol 38:209-214, 1962
55. Steinert PM, Marekov LN: The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelope. J Biol Chem 270:17702-17711, 1995
56. Steller H: Mechanisms and genes of cellular suicide. Science 267:1445-1449, 1995
57. Steven AC, Bisher ME, Roop DR, Steinert PM: Biosynthetic pathways of filaggrin and loricrin - two major proteins expressed by terminally differentiated epidermal keratinocytes. J Struct Biol 104:150-162, 1990
58. Takahashi M, Tezuka T, Katsunuma N: Filaggrin linker segment peptide and cystatin α are parts of a complex of the cornified envelope of epidermis. Arch Biochem Biophys 329:123-126, 1996
59. Takahashi H, Kinouchi M, Iizuka H: Interleukin-lβ-converting enzyme and CPP 32 are involved in ultraviolet B-induced apoptosis of SV40-transformed human keratinocytcs. Biochem Biophys Res Comm 236:194-198, 1997
60. Takahashi T, Ogo M, Hibino T: Partial purification and characterization of two distinct types of caspases from human epidermis. J Invest Dermatol 111:367-372, 1998
61. Takahashi H, Ishida-Yamamoto A, Kishi A, Ohara K, Iizuka H: Loricrin gene mutation in a Japanese patient of Vohwinkel's syndrome, J Dermatol Sci 19:44-47, 1999
62. Watt FM, Hertle MD, Keratinocyte integrins. In: Leigh I. Lane B, Watt F (eds). The Keratinocyte Handbook. Cambridge: Cambridge University Press, 1994, pp. 153-164
63. Wyllie AH, Kerr JFR, Currie AR: Cell death: the significance of apoptosis. Int Rev Cytology 68:251-306, 1980
64. Yamazaki M, Ishidoh K, Suga Y, et al. Cytoplasmic processing of human profilaggrin by active μ-calpain, Biochem Biophys Res Comm 235:652-656, 1997
65. Yoneda K, Hohl D, McBride OW, Wang M, Cebrs KU, Idler WW, Steinert PM: The human loricrin gene. J Biol Chem 267:18060-18066, 1992