Effect of oral vanadyl sulfate treatment on serum enzymes and lipids of streptozotocin-diabetic young rats

Molecular and Cellular Biochemistry

Volumn 198, Issue 1-2, 1999, Pages 157-161

  Pepato, Maria Teresa ^a   Magnani, Marcia R T ^b   Kettelhut, Isis C ^b   Brunetti, Iguatemy L ^b  

^a Fac Ci Farmaceut   (Brazil)

^b NONE

Author keywords

Diabetes mellitus; Hyperglycemia; Insulin; Serum enzymes; Vanadyl sulfate

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; INSULIN; LACTATE DEHYDROGENASE; VANADYL SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG COST; ENZYME BLOOD LEVEL; HYPERGLYCEMIA; LIPID BLOOD LEVEL; LIVER TOXICITY; MALE; MUSCLE; NONHUMAN; RAT; STREPTOZOCIN DIABETES;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CREATINE KINASE; DIABETES MELLITUS, EXPERIMENTAL; L-LACTATE DEHYDROGENASE; LIPIDS; MALE; RATS; RATS, WISTAR; STREPTOZOCIN; VANADIUM COMPOUNDS;

EID: 0032832023     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006917007148     Document Type: Article

References (25)

1. Lyonett, Martz, Martin: L'emploithérapeutique de derivés du vanadium. La Presse Medicale: 191-192, 1899
2. Nechay BR, Nanninga LB, Nechay PSE, Post RL, Grantham JJ, Macara IG, Kubena LF, Phillips TD, Nielsen FH: Role of vanadium in biology. Fed Proc 45: 123-132, 1986
3. Goldfine AB, Simonson DC, Folli F, Patti ME, Kahn CR: In vivo and in vitro studies of vanadate in human and rodent diabetes mellitus. Mol Cell Biochem 153: 217-231, 1995
4. Pepato MT, Magnani MRT, Brunetti IL, Kettelhut IC: Effects of oral vanadyl sulfate treatment in young diabetic rats. Rev Ciênc Farm 19: 1998 (in press)
5. Dubyak GR, Kleinzeller A: The insulin-mimetic effects of vanadate in isolated rat adipocytes. J Biol Chem 255: 5306-5312, 1980
6. Pâquet MR, Romanek RJ, Sargeant RJ: Vanadate induces the recruitment of glut-4 glucose transporter to the plasma membrane of rat adipocytes. Mol Cell Biochem 109: 149-155, 1992
7. Brichard SM, Okitolonda W, Henquin JC: Long term improvement of glucose homeostasis by vanadate treatment in diabetic rats. Endocrinology 123: 2048-2053, 1988
8. Meyrovitch J, Farfel Z, Sack J, Schechter Y: Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. J Biol Chem 262: 6658-6662, 1987
9. Ramanadham S, Mongold JJ, Brownsey RW, Cros GH, McNeill JH: Oral vanadyl sulfate in treatment of diabetes mellitus in rats. Am J Physiol 257: H904-H911, 1989
10. Cros G, Mongold JJ, Serrano JJ, Ramanadham S, McNeill JH: Effects of vanadyl derivatives on animal models of diabetes. Mol Cell Biochem 109: 163-166, 1992
11. Tolman EL, Barris E, Burns M, Prasini A, Partridge R: Effects of vanadium on glucose metabolism in vitro. Life Sci 25: 1159-1164, 1979
12. Foot E, Bliss T, Fernandes LC, Da Costa C, Leighton B: The effects of orthovanadate, vanadyl and peroxides of vanadate on glucose metabolism in skeletal muscle preparations in vitro. Mol Cell Biochem 109: 157-162, 1992
13. Clark AS, Pagan JM, Mitch WE: Selectivity of the insulin-like actions of vanadate on glucose and protein metabolism in skeletal muscle. Biochem J 232: 273-276, 1985
14. Pepato MT, Migliorini RH, Goldberg AL, Kettelhut IC: Role of different proteolytic pathways in degradation of muscle protein from streptozotocin-diabetic rats. Am J Physiol 271: E340-E347, 1996
15. Allain CA, Poon LS, Chan CSG, Richmond W, Fu PC: Enzymatic determination of total serum cholesterol. Clin Chem 20: 470-475, 1974
16. Soloni FG: Simplified manual micromethod for determination of serum triglycerides. Clin Chem 17: 529-534, 1971
17. King J: Enzimologia Clinica Practica. Acribia Ed., Zaragosa, 1968, pp 132-136
18. Committee on Enzymes, Scandinavian Society for Clinical Chemistry and Clinical Physiology: Recommended method for the determination of creatine kinase in blood. Scand J Clin Lab Invest 36: 711-723, 1976
19. Dorfman LE, Wacker WEC: Serum lactic dehydrogenase activity: an analytical assessment of current assays. Clin Chem 9: 391-399, 1963
20. Ramasarma T, Crane FI: Does vanadium play a role in cellular regulation? Curr Top Cellular Regul 20: 247-301, 1981
21. Gil-Gómez G, Ayté J, Hegardt G: The rat mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme-A-synthase gene contains elements that mediate its multihormonal regulation and tissue specifity. Eur J Biochem 213: 773-779, 1993
22. Yoshino G, Hirano T, Kazumi T: Dyslipidemia in diabetes mellitus. Diabetes Res Clin Prac 33: 1-14, 1996
23. Felig P, Bergman M: The endocrine pancreas: Diabetes mellitus. In: P. Felig, J.D. Baxter and L.A. Frohman (eds). Endocrinology and Metabolism. 3rd edn. McGraw-Hill Book Co, New York, 1995, pp 1107-1120
24. Lehninger AL, Nelson DL, Cox MM: Lipid biosynthesis. In: Principles of Biochemistry. 2nd edn. Worth Publishers, New York, 1993, pp 642-687
25. Pugazhenthi S, Khandelwal L: Insulinlike effects of vanadate on hepatic glycogen metabolism in nondiabetic and streptozotocin-induced diabetic rats. Diabetes 39: 821-827, 1990