Role of different proteolytic pathways in degradation of muscle protein from streptozotocin-diabetic rats

American Journal of Physiology - Endocrinology and Metabolism

Volumn 271, Issue 2 34-2, 1996, Pages

  Pepato, Maria Teresa ^a   Migliorini, Renato H ^c   Goldberg, Alfred L ^c   Kettelhut, Isis C ^b  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c NONE

Author keywords

adenosine triphosphate dependent proteolysis; calcium dependent proteolysis; lysosomal proteolysis; protein synthesis

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CALPAIN; CYCLOHEXIMIDE; FATTY ACID; INSULIN; LYSOSOME ENZYME; MUSCLE PROTEIN; PHENYLALANINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; EXTENSOR DIGITORUM LONGUS MUSCLE; FATTY ACID BLOOD LEVEL; GLUCOSE BLOOD LEVEL; INSULIN TREATMENT; MALE; MUSCLE MASS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; RAT; SOLEUS MUSCLE; STREPTOZOCIN DIABETES;

EID: 0029741353     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.271.2.e340     Document Type: Article

References (31)

1. Baracos, V. E., and A. L. Goldberg. Maintenance of normal length improves protein balance and energy status in isolated rat skeletal muscles. Am J. Physiol. 251 (Cell Physiol. 20): C588-C596, 1986.
2. DeMartino, G. N., and A. L. Goldberg. Thyroid hormones control lysosomal enzyme activities in liver and skeletal muscle. Proc Natl. Acad. Sci. USA 75: 1369-1373, 1978.
3. Dole, V. P., and H. Meinertz. Microdetermination of long-chain fatty acids in plasma and tissues. J. Biol. Chem. 235: 2595-2599, 1960.
4. Fagan, J. M., S. Satarug, P. Cook, and M. E. Tischler. Rat muscle protein turnover and redox state in progressive diabetes. Life Sci. 40: 783-790, 1987.
5. Fagan, J. M., L. Waxman, and A. L. Goldberg. Red blood cells contain a pathway for the degadation of oxidant-damaged hemoglobin that does not require ATP or ubiquitin. J. Biol. Chem. 261: 5705-5713, 1986.
6. Fagan, J. M., L. Waxman, and A. L. Goldberg. Skeletal muscle and liver contain a soluble ATP + ubiquitin-dependent proteolytic system. Biochem. J. 243: 335-343, 1987.
7. Fulks, R., J. B. Li, and A. L. Goldberg. Effects of insulin, glucose and amino acids on protein turnover in rat diaphragm. J. Biol. Chem. 250: 290-298, 1975.
8. Furuno, K., and A. L. Goldberg. The activation of protein degradation in muscle by calcium or muscle injury does not involve a lysosomal mechanism. Biochem. J. 237: 859-864, 1986.
9. Furuno, K., M. N. Goodman, and A. L. Goldberg. Role of different proteolytic systems in the degradation of muscle protein during denervation atrophy. J. Biol. Chem. 265: 8550-8557, 1990.
10. Goldberg, A. L., T. Lockwood, and P. Rodemann. Studies of the pathways of protein breakdown in skeletal muscle by use of protease inhibitors. In: Proc. Int. Congr. Muscular Dystrophy, edited by S. Ebashi. Tokyo: Univ. of Tokyo Press, 1982, p. 207-223.
11. Goodman, M. N. Myofibrillar protein breakdown in skeletal muscle is diminished in rats with chronic streptozotocin-induced diabetes. Diabetes 36: 100-105, 1987.
12. Hershko, A., and A. Ciechanover. The ubiquitin system for protein degradation. Annu. Rev. Biochem. 61: 761-807, 1992.
13. Jepson, M. M., P. C. Bates, and D. J. Millward. The role of insulin and thyroid hormones in the regulation of muscle growth and protein turnover in response to dietary protein in the rat. Br. J. Nutr. 59: 397-415, 1988.
14. Kadowaki, M., N. Harada, S. Takahashi, T. Noguchi, and H. Naito. Differential regulation of the degradation of myofibrillar and total protein in skeletal muscle of rats: effects of streptozotocin-induced diabetes, dietary protein and starvation. J. Nutr. 119: 471-517, 1989.
15. Kelly, F. J., and D. F. Goldspink. The differing responses of four muscle types to dexamethasone treatment in the rat. Biochem. J. 208: 147-151, 1982.
16. Kettelhut, I. C., S. S. Wing, and A. L. Goldberg. Endocrine regulation of protein breakdown in skeletal muscle. Diabetes Metab. Rev. 4: 751-772, 1988.
17. Li, J. B., and A. L. Goldberg. Effects of food deprivation on protein synthesis and degradation in rat skeletal muscles. Am. J Physiol. 231: 441-448, 1976.
18. Mitch, W. E., R. Medina, S. Grieber, R. C. May, B. K. England, S. R. Price, J. L. Bailey, and A. L. Goldberg. Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes. J. Clin. Invest. 93: 2127-2133, 1994.
19. Mortimore, G. E. Mechanism of cellular protein catabolism. Nutr. Rev. 40: 1-12, 1982.
20. 2--dependent protease (calpain) and its high molecular weight endogenous inhibitor (calpastatin). Adv. Enzyme Regul. 19: 407-424, 1981.
21. Pain, V. M., E. C. Albertse, and P. J. Garlick. Protein metabolism in skeletal muscle, diaphragm, and heart of diabetic rats. Am. J. Physiol. 245 (Endocrinol. Metab. 8): E604-E610, 1983.
22. Palmer, R. M., P. A. Bain, and P. J. Reeds. The effect of insulin and intermittent mechanical stretching on rates of protein synthesis and degradation in isolated rabbit muscle. Biochem. J. 230: 117-123, 1985.
23. Saudek, C. D., and P. Felig. The metabolic event of starvation. Am. J. Med. 60: 117-126, 1976.
24. Smith, O. L. K., C. Y. Wong, and R. A. Gelfand. Skeletal muscle proteolysis in rats with, acute streptozocin-induced diabetes. Diabetes 38: 1117-1122, 1989.
25. Sugden, P. H., and S. J. Fuller. Regulation of protein turnover in skeletal and cardiac muscle. Biochem. J. 273: 21-37, 1991.
26. Tawa, N. E., Jr., I. C. Kettelhut, and A. L. Goldberg. Dietary protein deficiency reduces lysosomal and nonlysosomal ATP-dependent proteolysis in muscle. Am. J. Physiol. 263 (Endocrinol. Metab. 26): E326-E334, 1992.
27. Tischler, M. E., M. Desautels, and A. L. Goldberg. Does leucine, leucyl-tRNA or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle? J. Biol. Chem. 257: 1613-1621, 1982.
28. Turner, R. R., T. Westwood, C. M. Regen, and R. A. Steinhardt. Increased protein degradation results from elevated free calcium levels found in muscle from mds mice. Nature Lond. 335: 735-738, 1988.
29. Waalkes, T. P., and S. Udenfriend. A fluorometric method for the estimation of tyrosine in plasma and tissues. J. Lab. Clin. Med. 50: 733-736, 1957.
30. Wing, S. S., and A. L. Goldberg. Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting. Am. J. Physiol. 264 (Endocrinol. Metab. 27): E668-E676, 1993.
31. Wing, S. S., A. L. Haas, and A. L. Goldberg. Increase in ubiquitin-protein conjugates concomitant with the increase in proteolysis in rat skeletal muscle during starvation and denervation atrophy. Biochem. J. 307: 639-645, 1995.