The catecholamines up (Catsup) protein of Drosophila melanogaster functions as a negative regulator of tyrosine hydroxylase activity

Genetics

Volumn 153, Issue 1, 1999, Pages 361-382

  Stathakis, Dean G ^a,c   Burton, Denise Y ^b   McIvor, Wilson E ^a   Krishnakumar, Sujatha ^b   Wright, Theodore R F ^a   O'Donnell, Janis M ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF ALABAMA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC LEVO AMINO ACID DECARBOXYLASE; CATECHOLAMINE; PROTEIN TYROSINE KINASE;

ARTICLE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME REGULATION; GENE LOCUS; GENE MUTATION; HORMONAL REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PROCESSING;

ANIMALS; CATECHOLAMINES; DOPAMINE; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; FEMALE; FERTILITY; GENES, DOMINANT; GENES, INSECT; GENES, LETHAL; GENOTYPE; INSECT PROTEINS; MALE; MELANINS; MUTATION; OOGENESIS; PHENOTYPE; SALIVARY GLANDS; TYROSINE 3-MONOOXYGENASE;

EID: 0032829708     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. ABOU-DONIA, M. M., S. P. WILSON, T. P. ZIMMERMAN, C. A. NICHOL and O. H. VIVEROS, 1986 Regulation of guanosine triphosphate cyclohydrolase and tetrahydrobiopterin levels and the role of the cofactor in tyrosine hydroxylation in primary cultures of adrenomedullary chromaffin cells. J. Neurochem. 46: 1190-1199.
2. ANDERSON, S. O., 1989a Enzymatic activities involved in incorporation of N-acetyl dopamine into insect cuticle during sclerolization. Insect Biochem. 19: 375-382.
3. ANDERSON, S. O., 1989b Oxidation of N-b-alanyl dopamine by insect cuticles and its role in cuticular sclerotization. Insect Biochem. 19: 581-586.
4. ASHBURNER, M., 1989 Drosophila: A Laboratory Handbook. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
5. BELTRAMI, E., and J. JESTY, 1995 Mathematical analysis of activation thresholds in enzyme-catalyzed positive feedbacks: application to the feedbacks of blood coagulation. Proc. Natl. Acad. Sci. USA 92: 8744-8748.
6. BIRMAN, S., B. MORGAN, M. ANZIVINO and J. HIRSH, 1994 A novel and major isoform of tyrosine hydroxylase in Drosophila is generated by alternative RNA processing. J. Biol. Chem. 269: 26559-26567.
7. BLACK, B. C., 1988 Studies of the genetics and biochemistry of catecholamine metabolism using Drosophila behavioral mutants, pp. 297-302 in Progress in Catecholamine Research, Part A: Basic Aspects and Peripheral Mechanisms, edited by A. DAHLSTROM, R. H. BELMAKER and M. SANDLER. Alan R. Liss, New York.
8. BLACK, B. C., E. S. PENTZ and T. R. F. WRIGHT, 1987 The alpha methyl-DOPA hypersensitive gene, l(2)amd, and two adjacent genes in Drosophila melanogaster. physical location and direct effects of amd on catecholamine metabolism. Mol. Gen. Genet. 209: 306-312.
9. BLAU, N., and A. NIEDERWIESER, 1985 GTP cyclohydrolase: a review. J. Clin. Chem. Clin. Biochem. 23: 169-176.
10. CHURCH, G. M., and W. GILBERT, 1984 Genomic sequencing. Proc. Natl. Acad. Sci. USA 81: 1991-1995.
11. EVELETH, D. D., and J. L. MARSH, 1986 Evidence for evolutionary duplication of genes in the DOPA decarboxylase region of Drosophila. Genetics 114: 469-483.
12. FILLENZ, M., 1993 Short-term control of transmitter synthesis in central catecholaminergic neurones. Prog. Biophys. Mol. Biol. 60: 29-46.
13. 1 of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 92: 7769-7773.
14. GAHN, L. G., and R. ROSKOSKI, JR., 1995 Thermal stability and CD analysis of rat tyrosine hydroxylase. Biochemistry 34: 252-256.
15. HARLOW, E., and D. LANE, 1988 Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
16. HESSLINGER, C., E. KREMMER, L. HULTNER, M. UEFFING and I. ZIEGLER, 1998 Phosphorylation of GTP cyclohydrolase I and modulation of its activity in rodent mast cells. GTP cyclohydrolase I hyperphosphorylation is coupled to high affinity IgE receptor signaling and involves protein kinase C. J. Biol. Chem. 273: 21616-21622.
17. HOPKINS, T. L., and K. J. KRAMER, 1992 Insect cuticle sclerotization. Annu. Rev. Entomol. 24: 127-222.
18. KAWAMURA, M., K. KOMINAMI, J. TAKEUCHI and A. TOH-E, 1996 A multicopy suppressor of nin1-1 of the yeast Saccharomyces cerevisiae is a counterpart of the Drosophila melanogaster diphenol oxidase A2 gene, Dox-A2. Mol. Gen. Genet. 251: 146-152.
19. KONRAD, K. D., D. WANG and J. L. MARSH, 1993 Vitelline membrane biogenesis in Drosophila requires the activity of the alpha-methyl dopa hypersensitive gene l(2)amd in both the germline and follicle cells. Insect Mol. Biol. 1: 179-187.
20. KUMER, S. C., and K. E. VRANA, 1996 Intricate regulation of tyrosine hydroxylase activity and gene expression. J. Neurochem. 67: 443-462.
21. LAPIZE, C., C. PLUSS, E. R. WERNER, A. HUWILER and J. PFEILSCHIFTER, 1998 Protein kinase C phosphorylates and activates GTP cyclohydrolase I in rat renal mesangial cells. Biochem. Biophys. Res. Commun. 251: 802-805.
22. LAZAR, M. A., R. J. TRUSCOTT, J. D. RAESE and J. D. W. BARCHAS, 1981 Thermal denaturation of native striatal tyrosine hydroxylase: increased thermolability of the phosphorylated form of the enzyme. J. Neurochem. 36: 677-682.
23. LINDSLEY, D. L., and G. G. ZIMM, 1992 The Genome of Drosophila melanogaster. Academic Press, San Diego.
24. MCLEAN, J. R., S. KRISHNAKUMAR and J. M. O'DONNELL, 1993 Multiple mRNAs from the Punch locus of Drosophila melanogaster encode isoforms of GTP cyclohydrolase I with distinct N-terminal domains. J. Biol. Chem. 268: 27191-27197.
25. MONASTIRIOTI, M., C. E. LINN, JR. and K. WHITE, 1996 Characterization of Drosophila tyramine β-hydroxylase gene and the isolation of mutant flies lacking octopamine. J. Neurosci. 16: 3900-3911.
26. NAGATSU, T., M. LEVITT and S. UDENFRIEND, 1964 Tyrosine hydroxylase: the initial step in norepinephrine biosynthesis. J. Biol. Chem. 239: 2910-2917.
27. NECKAMEYER, W. S., 1996 Multiple roles for dopamine in Drosophila development. Dev. Biol. 176: 209-219.
28. NECKAMEYER, W. S., and W. C. QUINN, 1989 Isolation and characterization of the gene for Drosophila tyrosine hydroxylase. Neuron 2: 1167-1175.
29. NECKAMEYER, W. S., and K. WHITE, 1993 Drosophila tyrosine hydroxylase is encoded by the pale locus. J. Neurogenet. 8: 189-199.
30. NÜSSLEIN-VOLHARD, C., E. WIESCHAUS and H. KLUDING, 1984 Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci of the second chromosome. Roux's Arch. Dev. Biol. 193: 267-282.
31. O'DONNELL, J. M., J. R. MCLEAN and E. R. REYNOLDS, 1989 Molecular and developmental genetics of the Punch locus, a pterin biosynthesis gene in Drosophila melanogaster. Dev. Genet. 10: 273-286.
32. PENTZ, E. S., and T. R. F. WRIGHT, 1986 A diphenol oxidase gene is part of a cluster of genes involved in catecholamine metabolism and sclerotization in Drosophila. II. Molecular localization of the Dox-A2 coding region. Genetics 112: 843-859.
33. PENTZ, E. S., B. C. BLACK and T. R. F. WRIGHT, 1986 A diphenol oxidase gene is part of a cluster of genes involved in catecholamine metabolism and sclerotization in Drosophila. I. Identification of the biochemical defect in Dox-A2 [l(2)37Bf] mutants. Genetics 112: 823-841.
34. PERRIMON, N., and M. GANS, 1983 Clonal analysis of the tissue specificity of recessive female-sterile mutations in Drosophila melanogaster using a dominant female-sterile mutation Fs(1)K1237. Dev. Biol. 100: 365-373.
35. PERRIMON, N., L. ENGSTROM and A. P. MAHOWALD, 1984 The effects of zygotic lethal mutations on female germline functions in Drosophila. Dev. Biol. 105: 404-414.
36. PERRIMON, N., L. ENGSTROM and A. P. MAHOWALD, 1989 Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. I. Loci on the X chromosome. Genetics 121: 333-352.
37. REED, K. C., and D. A. MANN, 1985 Rapid transfer of DNA from agarose gels to nylon membranes. Nucleic Acids Res. 13: 7207-7221.
38. RESTIFO, L. L., and K. WHITE, 1990 Molecular and genetic approaches to neurotransmitter and neuromodulator systems in Drosophila. Adv. Insect Physiol. 22: 116-219.
39. ROTER, A. H., J. B. SPOFFORD and H. SWIFT, 1985 Synthesis of the major adult cuticle proteins of Drosophila melanogaster during hypoderm differentiation. Dev. Biol. 107: 420-431.
40. SHEARN, A., 1978 Mutational dissection of imaginal disc development, pp. 443-510 in The Genetics and Biology of Drosophila, Vol. 2C, edited by M. ASHBURNER and T. R. F. WRIGHT. Academic Press, New York.
41. SMEETS, W. J. A. J., and A. REINER, 1994 Phylogeny and Development of Catecholamine Systems in the Central Nervous System of Vertebrates. Cambridge University Press, New York.
42. SPARROW, J. C., and T. R. F. WRIGHT, 1974 The selection for mutants in Drosophila melanogaster hypersensitive to a-methyl DOPA, a DOPA decarboxylase inhibitor. Mol. Gen. Genet. 130: 127-141.
43. SPRADLING, A. C., D. STERN, I. KISS, J. ROOTE, T. LAVERTY et al., 1995 Gene disruption using P transposable elements: an integral component of the Drosophila genome project. Proc. Natl. Acad. Sci. USA 92: 10824-10830.
44. STATHAKIS, D. G., 1998 The Catecholamines up (Catsup) locus of Drosophila melanogaster, a negative regulator of tyrosine hydroxylase activity. Ph.D. Thesis, University of Virginia, Charlottesville, VA.
45. STATHAKIS, D. G., E. S. PENTZ, M. E. FREEMAN, J. KULLMAN, G. R. HANKINS et al., 1995 The genetic and molecular organization of the Dopa decarboxylase gene cluster of Drosophila melanogaster. Genetics 141: 629-655.
46. SUGUMARAN, M., L. GIGLIO, H. KUNDZICZ, S. SAUL and V. SEMENSI, 1992 Studies on the enzymes involved in puparial cuticle sclerotization in Drosophila melanogaster. Arch. Insect Biochem. Physiol. 19: 271-283.
47. WANG, D., and J. L. MARSH, 1995 Developmental regulation of the a-methyl dopa hypersensitive gene of Drosophila melanogaster. Dev. Biol. 168: 598-612.
48. WRIGHT, T. R. F., 1987 The genetics of biogenic amine metabolism, sclerotization and melanization in Drosophila melanogaster. Adv. Genet. 24: 127-222.
49. WRIGHT, T. R. F., 1996 Phenotypic analysis of the Dopa decarboxylase gene cluster mutants in Drosophila melanogaster. J. Hered. 87: 175-190.
50. WRIGHT, T. R. F., G. C. BEWLEY and A. F. SHERALD, 1976 The genetics of DOPA decarboxylase in Drosophila melanogaster. II. Isolation and characterization of DOPA decarboxylase-deficient mutants and their relationship to the a-methyl-DOPA hypersensitive mutants. Genetics 84: 287-310.
51. WRIGHT, T. R. F., B. C. BLACK, C. P. BISHOP, J. L. MARSH, E. S. PENTZ et al., 1982 The genetics of DOPA decarboxylase in Drosophila melanogaster. V. Ddc and l(2)37amd alleles: isolation, characterization and intragenic complementation. Mol. Gen. Genet. 188: 18-26.
52. ZIGMOND, R. E., M. A. SCHWARTZSCHILD and A. R. RITTENHOUSE, 1989 Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation. Annu. Rev. Neurosci. 12: 415-461.