Decrease of cytomegalovirus replication in human immunodeficiency virus infected-patients after treatment with highly active antiretroviral therapy

Journal of Infectious Diseases

Volumn 180, Issue 3, 1999, Pages 847-849

  O'Sullivan, Cathal E ^c   Drew, W Lawrence ^a   McMullen, Dragana J ^a   Miner, Richard ^a   Lee, Jeanette Y ^d   Kaslow, Richard A ^d   Lazar, James G ^b   Saag, Michael S ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Digene Corp   (United States)

^c University of Alabama at Birmingham   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; VIRUS DNA; VIRUS RNA;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOCOMPETENCE; LYMPHOCYTE COUNT; MALE; NONHUMAN; PRIORITY JOURNAL; TREATMENT OUTCOME; VIREMIA; VIRUS INHIBITION; VIRUS LOAD;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIVIRAL AGENTS; CD4 LYMPHOCYTE COUNT; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA, VIRAL; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; LEUKOCYTES; MALE; RNA, VIRAL; VIRAL LOAD; VIRUS REPLICATION;

EID: 0032827474     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314943     Document Type: Article

References (10)

1. 1. Palella FJ, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998;338:853-60.
2. + T cell homeostasis and function in advanced HIV disease. Science 1997;277:112-6.
3. + T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1. Nature Med 1998;4:953-6.
4. 4. Tural C, Romeu J, Sirera G, et al. Long-lasting remission of cytomegalovirus retinitis without maintenance therapy in human immunodeficiency virus-infected patients. J Infect Dis 1998;177:1080-2.
5. 5. MacDonald JC, Torriani FJ, Morse LS, Karavellas MP, Reed JB, Freeman WR. Lack of reactivation of cytomegalovirus (CMV) retinitis after stopping CMV maintenance therapy in AIDS patients with sustained elevation in CD4 T cells in response to highly active antiretroviral therapy. J Infect Dis 1998;177:1182-7.
6. 6. Jacobson MA, Zegans M, Pavan PR, et al. Cytomegalovirus retinitis after initiation of highly active antiretroviral therapy. Lancet 1997;349:1443-5.
7. + T-cell repertoire that are not immediately restored by antiviral or immune-based therapies. Nature Med 1997;3:533-40.
8. 8. Salmon D, Lacassin F, Harzic M, Leport C, et al. Predictive value of cytomegalovirus viremia for the occurrence of CMV organ involvement in AIDS. J Med Virol 1990;32:160-3.
9. 9. Richardson WP, Colvin RB, Cheesman SH, et al. Glomerulopathy associated with cytomegalovirus viremia in renal allografts. N Engl J Med 1981;305: 57-67.
10. 10. Mazzulli T, Drew LW, Yen-Lieberman B, et al. A multicenter comparison of the digene hybrid capture CMV DNA assay (version 2.0), the pp65 antigenemia assay, and cell culture for detection of cytomegalovirus viremia. J Clin Microbiol 1999;37:958-63.