Comparison of different methods for separation and ex vivo expansion of cord blood progenitor cells

Annals of Hematology

Volumn 78, Issue 8, 1999, Pages 364-370

  Schwinger, W ^a   Benesch, M ^a   Lackner, H ^a   Kerbl, R ^a   Walcher, M ^b   Urban, C ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b NONE

Author keywords

Cord blood stem cells; Expansion; Purification; Selection

Indexed keywords

CD34 ANTIGEN; CYTOKINE; ERYTHROPOIETIN; FICOLL; GELATIN; GRANULOCYTE COLONY STIMULATING FACTOR; HETASTARCH; INTERLEUKIN 3; MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR;

ARTICLE; CELL SELECTION; CELL SEPARATION; COLONY FORMING CELL; CULTURE MEDIUM; DENSITY GRADIENT; ERYTHROCYTE; FETAL CALF SERUM; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; MAGNET; PRIORITY JOURNAL; UMBILICAL CORD BLOOD;

ANTIGENS, CD34; BLOOD COMPONENT REMOVAL; CELL SEPARATION; COLONY-FORMING UNITS ASSAY; CYTAPHERESIS; ERYTHROCYTE TRANSFUSION; ERYTHROID PROGENITOR CELLS; FEMALE; FETAL BLOOD; GRANULOCYTES; HEMATOPOIETIC STEM CELLS; HUMANS; MACROPHAGES; MEGAKARYOCYTES; MONOCYTES; PREGNANCY;

EID: 0032826667     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002770050530     Document Type: Article

References (26)

1. Wagner JE, Keman NA, Steinbuch M, Broxmeyer HE, Gluckman E (1995) Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease. Lancet 346:214-219
2. Gluckman E, Rocha V, Boyer-Chammard A, Locatelli F, Arcese W, Pasquini R, Ortega J, Souillet G, Ferreira E, Laporte JP, Femandez M, Chastang C (1997) Outcome of cord-blood transplantation from related and unrelated donors. N Engl J Med 337:373-381
3. J Rubinstein P, Dobrila L, Rosenfield RE, Adamson JW, Migliaccio G, Migliaccio AR, Taylor PE, Stevens CE (1996) New York Blood Center's program for unrelated placental/ umbilical cord blood transplantation: 243 transplants in the first three years. Blood 88:142a (abstract)
4. Kurtzberg J, Laughlin M, Graham ML, Smith C, Olson JF, Halperin EC, Ciocci G, Carrier C, Stevens CE, Rubinstein P (1996) Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Engl J Med 335:157-166
5. Gluckman E, Broxmeyer HA, Auerbach AD, Friedman HS, Douglas GW, Devergie A, Esperou H, Thierry D, Socie G, Lehn P (1989) Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical cord blood from an HLA-identical sibling. N Engl J Med 321:1174-1178
6. Kögler G, Callejas J, Sorg RV, Fischer J, Migliaccio AR, Wemet P (1998) The effect of different thawing methods, growth factor combinations and media on the ex vivo expansion of umbilical cord blood primitive and committed progenitors. Bone Marrow Transplant 21:233-241
7. Harris DT, Schumacher MJ, Rychlik S, Booth A, Acevedo A, Rubinstein P, Bard J, Boyse EA (1994) Collection, separation and cryopreservation of umbilical cord blood for use in transplantation. Bone Marrow Transplant 13:135-143
8. Broxmeyer HE, Kurtzberg J, Gluckman E, Auerbach AD, Douglas G, Cooper S, Falkenburg JH, Bard J, Boyse EA (1991) Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation. Blood Cells 17:313-329
9. Gluckman E, Devergie A, Thierry D, Esperou-Bourdeau H. Traineau R, Gerrota J, Brossard Y, van-Nifterik J, Benbunan M (1992) Clinical applications of stem cell transfusion from cord blood and rationale for cord blood banking. Bone Marrow Transplant 9 [Suppl 1]: 114-117
10. Screnci M, De Felice L, Carmini D, Picardi A, Arcese W (1995) Does the type of delivery influence umbilical cord blood recovery? (letter) Bone Marrow Transplant 16:631-632
11. Pahwa RN, Fleischer A, Than S, Good RA (1994) Successful hematopoietic reconstitution with transplantation of erythrocyte-depleled allogeneic human umbilical cord blood cells in a child with leukemia. Proc Natl Acad Sci U S A 91:4485-4488
12. Rubinstein P, Dobrila L, Rosenfield RE, Adamson JW, Migliaccio G, Migliaccio AR, Taylor PE, Stevens CE (1995) Processing and cryopreservation of placental/umbilical cord blood for unrelated bone marrow reconstitution. Proc Natl Acad Sci U S A 92:10119-10122
13. Bertolini F, Battaglia M, Zibera C, Baroni G, Soro V, Perotti C, Salvaneschi L, Robustelli-della-Cuna G (1996) A new method for placental/cord blood processing in the collection bag. Analysis of factors in red blood cell removal. Bone Marrow Transplant 18:783-786
14. Moore MA, Hoskins I (1994) Ex vivo expansion of cord blood derived stem cells and progenitors. Blood Cells 20:468-481
15. Broxmeyer HE, Hangoc G, Cooper S, Ribeiro RC, Graves V, Yoder M, Wagner J, Vadhan-Raj S, Benninger L, Rubinstein P (1992) Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults. Proc Natl Acad Sci U S A 89:4109-4113
16. Migliaccio G, Migliaccio AR, Druzin ML, Giardina PJ, Zsebo KM, Adamson JW (1992) Long-term generation of colony-forming cells in liquid culture of CD34+ cord blood cells in the presence of recombinant human stem cell factor. Blood 79:2620-2627
17. Mayani H, Dragowska W, Lansdorp PM (1993) Characterization of functionally distinct subpopulations of CD34+ cord blood cells in serum-free long-term cultures supplemented with hematopoietic cytokines. Blood 82:2664-2672
18. Williams DA (1993) Ex vivo expansion of hematopoietic stem and progenitor cells: robbing Peter to pay Paul ? Blood 81:3169-3172
19. Lansdorp PM, Dragowska W (1993) Maintenance of hematopoiesis in serum-free bone marrow cultures involves sequential recruitment of quiescent progenitors. Exp Hematol 21:1321-1327
20. Migliaccio AR, Baiocchi M, Durand B, Eddleman K, Migliaccio G, Adamson JW (1994) Stem cell factor and the amplification of progenitor cells from CD34+ cord blood cells. Blood Cells 20:129-139
21. Broxmeyer HE, Lu L, Cooper S, Ruggieri L, LI ZH, Lyman SD (1995) Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells. Exp Hematol 23:1121-1129
22. Yurasov SV, Flasshove M, Rafli S, Moore MA (1996) Density enrichment and characterization of hematopoietic progenitors and stem cells from umbilical cord blood. Bone Marrow Transplant 17:517-525
23. Piacibello W, Sanavio F, Garetto L, Severino A, Bergandi D, Ferrario J, Fagioli F, Berger M, Aglietta M (1997) Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. Blood 89:2644-2653
24. Sutherland HJ, Lansdorp PM, Henkelman DH, Eaves AC, Eaves CJ (1990) Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive stromal layers. Proc Natl Acad Sci U S A 87:3584-3588
25. Berardi AC, Wang A, Levine JD, Lopez P, Scadden DT (1995) Functional isolation and characterization of human hematopoietic stem cells. Science 267:104-108
26. McKenna HJ, de-Vries P, Brasel K, Lyman SD, Williams DE (1995) Effect of flt3 ligand on the ex vivo expansion of human CD34+ hematopoietic progenitor cells. Blood 86:3413-3420