A novel gene required for cercosporin toxin resistance in the fungus Cercospora nicotianae

Molecular and General Genetics

Volumn 262, Issue 2, 1999, Pages 382-389

  Chung, K R ^a   Jenns, A E ^a   Ehrenshaft, M ^a   Daub, M E ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Genetic complementation; Integral membrane protein; Singlet oxygen; Targeted gene disruption

Indexed keywords

MYCOTOXIN; SINGLET OXYGEN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DATA BASE; DOWN REGULATION; FUNGUS; GENE CONTROL; GENE DISRUPTION; GENETIC COMPLEMENTATION; GENETIC RESISTANCE; GENOME; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOUTHERN BLOTTING;

AMINO ACID SEQUENCE; ASCOMYCOTA; BASE SEQUENCE; CLONING, MOLECULAR; DNA, FUNGAL; FUNGAL PROTEINS; GENE EXPRESSION; GENES, FUNGAL; GENETIC COMPLEMENTATION TEST; MOLECULAR SEQUENCE DATA; MUTATION; PERYLENE; PHENOTYPE; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0032825305     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380051097     Document Type: Article

References (32)

1. Agabian N (1990) Trans splicing of nuclear pre-mRNAs. Cell 61:1157-1160
2. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402
3. Byrd AD, Schardl CL, Songlin PJ, Morgen KL, Siegel MR (1990) The β-tubulin gene of Epichloë typhina from perennial ryegrass (Lolium perenne) Curr Genet 18:347-354
4. Callahan TM, Rose MS, Meade MJ, Ehrenshaft M, Upchurch RG (1999) CFP, the putative cercosporin transporter of Cercospora kikuchii, is required for wild type cercosporin production, resistance, and virulence on soybean. Mol Plant Microb Interact, in press
5. Chung KR, Leuchtmann A, Schardl CL (1996) Inheritance of mitochondrial DNA and plasmids in the ascomycetous fungus, Epichloë typhina. Genetics 142:259-265
6. Daub ME (1982) Peroxidation of tobacco membrane lipids by the photosensitizing toxin, cercosporin. Plant Physiol 69:1361-1364
7. Daub ME (1987) Resistance of fungi to the photosensitizing toxin, cercosporin. Phytopathol 77:1515-1520
8. Daub ME, Ehrenshaft M (1993) The photoactivated toxin cercosporin as a tool in fungal photobiology. Physiol Plant 89:227-236
9. Daub ME, Hangarter RP (1983) Production of singlet oxygen and superoxide by the fungal toxin, cercosporin. Plant Physiol 73:855-857
10. Daub ME, Leisman GB, Clark RA, Bowden EF (1992) Reduced detoxification as a mechanism of fungal resistance to singlet-oxygen-generating photosensitizers. Proc Natl Acad Sci USA 89:9588-9592
11. Daub ME, Ehrenshaft M, Jenns AE, Chung KR (1998) Active oxygen in fungal pathogenesis of plants: the role of cercosporin in Cercospora Diseases. In: Romeo JT, Downum KR, Verpoorte R (eds) Photochemical signals and plant-microbe interactions. Plenum Press, New York, pp 31-56
12. Devereux J, Haeberli P, Smithies O (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res 12:387-395
13. Diwu Z (1995) Novel therapeutic and diagnostic applications of hypocrellins and hypericins. Photochem Photobiol 61:529-539
14. Ehrenshaft M, Jenns AE, Daub ME (1995) Targeted gene disruption of carotenoid biosynthesis in Cercospora nicotianae reveals no role for carotenoids in photosensitizer resistance. Mol Plant Microb Interact 8:569-575
15. Ehrenshaft M, Jenns AE, Chung KR, Daub ME (1998) SOR1, a gene required for photosensitizer and singlet oxygen resistance in Cercospora fungi, is highly conserved in divergent organisms. Mol Cell 1:603-609
16. Ehrenshaft M, Chung KR, Jenns AE, Daub ME (1999) Functional characterization of SOR1, a gene required for resistance to photosensitizing toxins in the fungus Cercospora nicotianae. Curr Genet 34:478-485.
17. Girotte AW (1990) Photodynamic lipid peroxidation in biological systems. Photochem Photobiol 51:497-509
18. Heitz JR, Downum KR (1987) Light-activated pesticides. ACS Symposium Series No. 339, American Chemical Society, Washington, DC
19. Hudson JB, Towers GHN (1991) Therapeutic potential of plant photosensitizers. Pharmacol Ther 49:181-222
20. Hudson JB, Zhou J, Chen J, Harris L, Yip L, Towers GHN (1994) Hypocrellin, from Hypocrella bambusae, is phototoxic to human immunodeficiency virus. Photochem Photobiol 60:253-255
21. Jenns AE, Daub ME (1995) Characterization of mutants of Cercospora nicotianae sensitive to the toxin cercosporin. Phytopathology 85:906-912
22. Jenns AE, Daub ME, Upchurch RG (1989) Regulation of cercosporin accumulation in culture by medium and temperature manipulation. Phytopathology 79:213-219
23. Jenns AE, Scott DL, Bowden EF, Daub ME (1995) Isolation of mutants of the fungus Cercospora nicotianae altered in their response to singlet-oxygen-generating photosensitizers. Photochem Photobiol 61:488-493
24. Kyte J, Doolittle RF (1982) A simple method for displaying the hydropathic character of a protein. J Mol Biol 157:105-132
25. Leisman GB, Daub ME (1992) Singlet oxygen yields, optical properties, and phototoxicity of reduced derivatives of the photosensitizer cercosporin. Photochem Photobiol 55:373-379
26. Pall ML, Brunelli JP (1993) A series of six compact fungal transformation vectors containing polylinkers with multiple unique restriction sites. Fungal Genet Newslett 40:59-62
27. Rogers S, Wells R, Rechsteiner M (1986) Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science 234:364-368
28. Sanford JC, Johnston SA (1985) The concept of parasite-derived resistance - deriving resistance genes from the parasites' own genome. J Theor Biol 113:395-495
29. Sollod CC, Jenns AJ, Daub ME (1992) Cell surface redox potential as a mechanism of defense against photosensitizers in fungi. Appl Environ Microbiol 58:444-449
30. Spikes JD (1989) Photosensitization. In: Smith KC (ed) The Science of photobiology. Plenum Press, New York, pp 79-110
31. Straubinger B, Straubinger E, Wirsel S, Turgeon G, Yoder OC (1992) Versatile fungal transformation vectors carrying the selectable bar gene of Streptomyces hygroscopicus. Fungal Genet Newslett 39:82-83
32. Tamaoki T, Nakano H (1990) Potent and specific inhibitors of protein kinase C of microbial origin. Biotechnology 8:732-735