Assessment of bovine leukemia virus transcripts in vivo

Journal of Virology

Volumn 73, Issue 10, 1999, Pages 8890-8897

  Rovnak, Joel ^a,b   Casey, James W ^a  

^a Animal Health Diagnostic Center   (United States)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REX PROTEIN; TAX PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BOVINE LEUKEMIA VIRUS; CONTROLLED STUDY; LYMPHOCYTOSIS; LYMPHOMA; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; VIRUS GENOME; VIRUS TRANSCRIPTION;

EID: 0032824655     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.10.8890-8897.1999     Document Type: Article

References (55)

1. Alexandersen, S., S. Carpenter, J. Christensen, T. Storgaard, B. Viuff, Y. Wannemuehler, J. Belousov, and J. A. Roth. 1993. Identification of alternatively spliced mRNAs encoding potential new regulatory proteins in cattle infected with bovine leukemia virus. J. Virol. 67:39-52.
2. Béraud, C., S.-C. Sun, P. Ganchi, D. W. Ballard, and W. C. Greene. 1994. Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-KB2 p100 gene product: implications for viral latency. Mol. Cell. Biol. 14:1374-1382.
3. Bhat, N. K., Y. Adachi, K. P. Samuel, and D. Derse. 1993. HTLV-1 gene expression by defective proviruses in an infected T-cell line. Virology 196: 15-24.
4. Boros, I. M., F. Tie, and C.-Z. Giam. 1995. Interaction of bovine leukemia virus transactivator Tax with bZip proteins. Virology 214:207-214.
5. Brauweiler, A., J. E. Garrus, J. C. Reed, and J. K. Nyborg. 1997. Repression of bax gene expression by the HTLV-I Tax protein: implications for suppression of apoptosis in virally infected cells. Virology 231:135-140.
6. Chiba, T., T. Ajito, and K. Okada. 1994. Phenotype analysis of lymphocytes present in different stages of neoplasia induced by bovine leukemia virus. Leukemia 8:S206-S210.
7. Ciminale, V., G. N. Pavlakis, D. Derse, C. P. Cunningham, and B. K. Felber. 1992. Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: novel mRNAs and proteins produced by HTLV type I. J. Virol. 66:1737-1745.
8. Ciminale, V., L. Zotti, D. M. D'Agostino, and L. Chieco-Bianchi. 1997. Inhibition of human T-cell leukemia virus type 2 Rex function by truncated forms of Rex encoded in alternatively spliced mRNAs. J. Virol. 71:2810-2818.
9. Cockerell, G. L., and J. Rovnak. 1988. The correlation between the direct and indirect detection of bovine leukemia virus infection in cattle. Leuk. Res. 12:465-469.
10. Cockerell, G. L., J. Rovnak, P. L. Green, and I. S. Y. Chen. 1996. A deletion in the proximal untranslated pX region of human T-cell leukemia virus type II decreases viral replication but not infectivity in vivo. Blood 87:1030-1035.
11. Derse, D. 1987. Bovine leukemia virus transcription is controlled by a virus-encoded trans-acting factor and by cis-acting response elements. J. Virol. 61:2462-2471.
12. Derse, D. 1988. trans-acting regulation of bovine leukemia virus mRNA processing. J. Virol. 62:1115-1119.
13. Derse, D., and J. W. Casey. 1986. Two elements in the bovine leukemia virus long terminal repeat that regulate gene expression. Science 231:1437-1440.
14. Edmands, S., J. Kirk, A. Lee, and J. Radich. 1994. Rapid RT-PCR amplification from limited cell numbers. PCR Methods Appl. 3:317-319.
15. Felber, B. K., D. Derse, A. Athanassopoulos, M. Campbell, and G. N. Pavlakis. 1989. Cross-activation of the Rex proteins of HTLV-I and BLV and of the Rev protein of HIV-I and nonreciprocal interactions with their RNA responsive elements. New Biol. 1:318-328.
16. Ferrer, J. F., N. D. Stock, and P. Lin. 1971. Detection of replicating C-type viruses in continuous cell cultures established from cows with leukemia: effect of the culture medium. J. Natl. Cancer Inst. 47:613-621.
17. Fujii, M., P. Sassone-Corsi, and I. M. Verma. 1988. c-fos promoter transactivation by the taxi protein of human T-cell leukemia virus type 1. Proc. Natl. Acad. Sci. USA 85:8526-8530.
18. Gaynor, E. M., M. L. Mirsky, and H. A. Lewin. 1996. Use of flow cytometry and RT-PCR for detecting gene expression by single cells. BioTechniques 21:286-291.
19. Haas, L., T. Divers, and J. W. Casey. 1992. Bovine leukemia virus gene expression in vivo. J. Virol. 66:6223-6225.
20. Heeny, J. L., P. J. S. Valli, R. M. Jacobs, and V. E. O. Valli. 1992. Evidence for bovine leukemia virus infection of peripheral blood monocytes and limited antigen expression in bovine lymphoid tissue. Lab. Investig. 66:608-617.
21. Hirai, H., T. Suzuki, J. Fujisawa, J. Inoue, and M. Yoshida. 1994. Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappaB proteins for transcriptional activation. Proc. Natl. Acad. Sci. USA 91:3584-3588.
22. Jeang, K.-T., S. G. Widen, O. J. Semmes, and S. H. Wilson. 1990. HTLV-I transactivator protein, Tax, is a trans-repressor of the human beta-polymerase gene. Science 247:1082-1084.
23. Jensen, W. A., J. Rovnak, and G. L. Cockerell. 1991. In vivo transcription of the bovine leukemia virus tax/rex region in normal and neoplastic lymphocytes of cattle and sheep. J. Virol. 65:2484-2490.
24. Jensen, W. A., B. J. Wicks-Beard, and G. L. Cockerell. 1992. Inhibition of protein kinase C results in decreased expression of bovine leukemia virus. J. Virol. 66:4427-4433.
25. Jin, D.-Y., F. Spencer, and K.-T. Jeang. 1998. Human T-cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. Cell 93:81-91.
26. Katoh, I., Y. Yoshinaka, and Y. Ikawa. 1989. Bovine leukemia virus transactivator p34Tax activates heterologous promoters with a common sequence known as a cAMP-responsive element or the binding site of a cellular transcription factor ATF. EMBO J. 8:497-503.
27. Kerkhofs, P., H. Heremans, A. Burny, R. Kettman, and L. Willems. 1998. In vitro and in vivo oncogenic potential of bovine leukemia virus G4 protein. J. Virol. 72:2554-2559.
28. Kettmann, R., A. Burny, I. Callebaut, L. Droogmans, M. Mammericks, L. Willems, and D. Portetelle. 1994. Bovine leukemia virus, vol. 3. Plenum Press, New York, N.Y.
29. x protein. Virology 220:502-507.
30. Lagarias, D. M., and K. Radke. 1989. Transcriptional activation of bovine leukemia virus in blood cells from experimentally infected, asymptomatic sheep with latent infections. J. Virol. 63:2099-2107.
31. McCulloch, R. K., C. S. Choong, and D. M. Hurley. 1995. An evaluation of competitor type and size for use in the determination of mRNA by competitive PCR. PCR Methods Appl. 4:219-226.
32. Mirsky, M. L., C. A. Olmstead, Y. Da, and H. A. Lewin. 1996. The prevalence of proviral bovine leukemia virus in peripheral blood mononuclear cells at two subclinical stages of infection. J. Virol. 70:2178-2183.
33. Neuveut, C., K. G. Low, F. Maldarelli, I. Schmitt, F. Majone, R. Grassmann, and K.-T. Jeang. 1998. Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb. Mol. Cell. Biol. 18:3620-3632.
34. Orita, O., S. Sato, Y. Aono, N. Minoura, T. Yamashita, Y. Hinuma, and H. Igarashi. 1993. Identification of novel singly spliced pX mRNA transcripts common to all human T-cell leukemia virus type 1-related retroviruses. Virus Genes 7:197-204.
35. Orita, S., H. Kobayashi, Y. Aono, A. Saiga, M. Maeda, and H. Igarashi. 1993. p21X mRNA is expressed as a singly spliced transcript from defective provirus genomes having a partial deletion of the pol-env region in human T-cell leukemia virus type 1-infected cells. Nucleic Acids Res. 21:3799-3807.
36. Pise-Masison, C. A., M. Radonovich, K. Sakaguchi, E. Appella, and J. N. Brady. 1998. Phosphorylation of p53: a novel pathway for p53 inactivation in human T-cell lymphotropic virus type 1-transformed cells. J. Virol. 72:6348-6355.
37. Reid, R. L., P. F. Lindholm, A. Mireskandari, J. Dittmer, and J. N. Brady. 1993. Stabilization of wildtype p53 in human T lymphocytes transformed by HTLV-1. Oncogene 8:3029-3036.
38. Reyes, R. A., and G. L. Cockerell. 1996. Unintegrated bovine leukemia virus DNA: association with viral expression. J. Virol. 70:4961-4965.
39. Rice, N. R., R. M. Stephens, D. Couez, J. Deschamps, R. Kettmann, A. Burny, and R. Gilden. 1984. The nucleotide sequence of the env and post-env region of bovine leukemia virus. Virology 138:82-93.
40. Rosen, C. A., J. Sodroski, R. Kettmann, A. Burny, and W. Haseltine. 1984. Trans activation of the bovine leukemia virus long terminal repeat in BLV-infected cells. Science 227:320-322.
41. Sagata, N., J. Tsuzuku-Kawamura, M. Nagayoshi-Aida, F. Shimizu, K. I. Imagawa, and Y. Ikawa. 1985. Identification of some biochemical properties of the major XBL gene product of bovine leukemia virus. Proc. Natl. Acad. Sci. USA 82:7879-7883.
42. Sagata, N., T. Yasunaga, J. Tsuzuku-Kawamura, K. Ohishi, Y. Ogawa, and Y. Ikawa. 1985. Complete nucleotide sequence of the genome of bovine leukemia virus: its evolutionary relationship to other retroviruses. Proc. Natl. Acad. Sci. USA 82:677-681.
43. Schnurr, M. W., R. F. Carter, I. D. Dube, V. E. Valli, and R. M. Jacobs. 1994. Nonrandom chromosomal abnormalities in bovine lymphoma. Leuk. Res. 18:91-99.
44. INK4A and counteracts its inhibitory activity towards CDK4. EMBO J. 15:1607-1614.
45. Takashima, I., and C. Olson. 1980. Effect of mitogens and anti-bovine leukosis serums on DNA synthesis of lymphocytes from cattle. Eur. J. Cancer 16:639-645.
46. Uittenbogaard, M., A. P. Armstrong, A. Chiaramello, and J. K. Nyborg. 1994. HTLV-I Tax protein represses gene expression through the bHLH family of transcription factors. J. Biol. Chem. 269:22466-22469.
47. Uittenbogaard, M., H. A. Giebler, D. Reisman, and J. K. Nyborg. 1995. Transcriptional repression of p53 by human T-cell leukemia virus type 1 tax protein. J. Biol. Chem. 270:28503-28506.
48. Van Der Maaten, M. J., and J. M. Miller. 1976. Replication of bovine leukemia virus in monolayer cell cultures. Bibl. Haematol. 43:360-362.
49. Willems, L., A. Gegonne, G. Chen, A. Burny, R. Kettmann, and J. Ghysdael. 1987. The bovine leukemia virus p34 is a transactivator protein. EMBO J. 6:3385-3389.
50. Willems, L., C. Grimonpont, H. Heremans, N. Rebeyrotte, G. Chen, D. Portetelle, A. Burny, and R. Kettmann. 1992. Mutations in the bovine leukemia virus tax protein can abrogate the long terminal repeat-directed trans-activating activity without concomitant loss of transforming potential. Proc. Natl. Acad. Sci. USA 89:3957-3961.
51. Willems, L., H. Heremans, G. Chen, D. Portetelle, A. Billiau, A. Burny, and R. Keltmann. 1990. Cooperation between bovine leukemia virus transactivator protein and Ha-ras oncogene in cellular transformation. EMBO J. 9:1577-1581.
52. Willems, L., P. Kerkhofs, F. Dequiedt, D. Portetelle, M. Mammerickx, A. Burny, and R. Kettmann. 1994. Attenuation of bovine leukemia virus by deletion of R3 and G4 open reading frames. Proc. Natl. Acad. Sci. USA 91:11532-11536.
53. Willems, L., R. Kettmann, G. Chen, D. Portetelle, A. Burny, and D. Derse. 1992. A cyclic AMP-responsive DNA-binding protein (CREB2) is a cellular transactivator of the bovine leukemia virus long terminal repeat. J. Virol. 66:766-772.
54. Willems, L., R. Kettmann, F. Dequiedt, D. Portetelle, V. Vonèche, I. Cornil, P. Kerkhofs, A. Burny, and M. Mammerickx. 1993. In vivo infection of sheep by bovine leukemia virus mutants. J. Virol. 67:4078-4085.
55. Yoshinaka, Y., and S. Oroszian. 1985. Bovine leukemia virus post-envelope gene coded protein: evidence for expression in natural infection. Biochem. Biophys. Res. Commun. 131:347-354.