Assessment of the respiratory actions of intramuscular morphine in conscious dogs

Research in Veterinary Science

Volumn 67, Issue 2, 1999, Pages 141-148

  Cullen, L K ^a   Raffe, M R ^b   Randall, D A ^b   Bing, D R ^c  

^a MURDOCH UNIVERSITY   (Australia)

^b UNIVERSITY OF MINNESOTA   (United States)

^c CHILDREN S HOSPITALS AND CLINICS OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; MORPHINE; OXYGEN;

ANIMAL EXPERIMENT; ARTICLE; BREATHING MECHANICS; BREATHING RATE; CONSCIOUSNESS; CONTROLLED STUDY; DOG; DOSE RESPONSE; END TIDAL CARBON DIOXIDE TENSION; FACE MASK; FEMALE; INTRAMUSCULAR DRUG ADMINISTRATION; LUNG MINUTE VOLUME; MALE; MATHEMATICAL ANALYSIS; NONHUMAN; PEAK EXPIRATORY FLOW; TIDAL VOLUME;

ANIMALIA; CANIS FAMILIARIS;

EID: 0032819278     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1053/rvsc.1998.0293     Document Type: Article

References (32)

1. AMIS, T. C. & KURPERSHOEK, C. (1986) Tidal Breathing Flow-Volume Loop Analysis for Clinical Assessment of Airway Obstruction in Conscious Dogs. American Journal of Veterinary Research. 47, 1002-1006.
2. AMIS, T. C., SMITH, M. M., GABER, C. E. & KURPERSHOEK, C. (1986) Upper Airway Obstruction in Canine Laryngeal Paralysis. American Journal of Veterinary Research. 47, 1007-1010.
3. BELLVILLE, J. W. & SEED, J. C. (1960) The Effect of Drugs on the Respiratory Response to Carbon Dioxide. Anesthesiology. 21, 727-741.
4. BERG, R. J. & ORTON, E. C. (1986) Pulmonary Function in Dogs after Intercostal Thoracotomy: Comparison of Morphine, Oxymorphone and Selective Intercostal Nerve Blocks. American Journal of Veterinary Research. 47, 471-474.
5. BORGBJERG, F. M., NIELSEN, K. & FRANKS, J. (1996) Experimental Pain Stimulates Respiration and Attenuates Morphine-Induced Respiratory Depression: a Controlled Study in Human Volunteers. Pain. 64, 123-128.
6. BOUVEROT, P., FLANDROIS, R., PUCINELLE, R. & DEJOURS, P. (1965) Etude du Role des Chemoredepteurs Arteriels dans la Regulation de la Respiration Pulmonaire Dhez le Chien Eveille. Archives internationales de Pharmacodynamie et de Therapie 157, 253-271.
7. BROCK, N (1995) Treating Moderate and Severe Pain in Small Animals. Canadian Veterinary Journal. 36, 658-660.
8. DHOKARIKAR, P., CAYWOOD, D. D., STOBIE, D., RAFFE, M. R., ALBRECHT, M., KANNAN, M., KING, V., HEGSTAD, B. & RANDALL, D. (1996) Effects of Intramuscular or Interpleural Administration of Morphine and Interpleural Administration of Bupivacaine on Pulmonary Function in Dogs that have undergone Median Sternotomy. American Journal of Veterinary Research. 57, 375-380.
9. DOOHOO, S., TASKER, R. A. R. & DONALD, A. (1994) Pharmacokinetics of Parenteral and Oral Sustained - Release Morphine Sulphate in Dogs. Journal of Veterinary Pharmacology and Therapeutics. 17, 426-433.
10. FLOREZ, J., McCARTHY, L. E. & BORISON, H. L. (1968) A Comparative Study in the Cat of the Respiratory Effects of Morphine Injected Intravenously and into the Cerebrospinal Fluid. Journal of Pharmacology and Experimental Therapeutics. 163, 448-455.
11. GANONG, W. F. (1993) Review of Medical Physiology. 16th edn. Lange Medical Publications, Los Altos. p 225.
12. HALL, L. W. & CLARKE, K. W. (1991) Veterinary Anaesthesia. 9th edn. Bailiere Tindall, London. pp 64-72.
13. HANSEN, B. D. (1994) Analgesic Therapy. Compendium of Continuing Education for the Practicing Veterinarian. 16, 868-873.
14. HASKINS, S. C. (1987) Use of Analgesics Postoperatively and in a Small Animal Intensive Care Setting. Journal of the Americal Veterinary Medical Association. 191, 1266-1268.
15. HUG, C. C., MURPHY, M. R., RIGEL, E. P. & OLSEN, W. A. (1981) Pharmacokinetics of Morphine Injected intravenoulsy into the Anesthetized Dog. Anesthesiology. 54, 38-47.
16. KEATS, A. S. (1985) The Effect of Drugs on Respiration on Man. Annual Review: Pharmacology and Toxicology. 25, 41-65.
17. KING, L. G., DROBATZ, K. J. & HENDRICKS, J. C. (1991) Static Thoracic Compliance as a Measurement of Pulmonary Function in Dogs. American Journal of Veterinary Research. 52, 1597-1601.
18. LAMBERTSEN, C. J. (1966) Drugs and Respiration. Annual Review of Pharmacology. 6, 327-378.
19. MARTIN, W. R. (1983) Pharmacology of Opioids. Pharmacological Reviews. 35, 285-323.
20. McKIERNAN, B. C. & JOHNSON, L. R. (1992) Clinical Pulmonary Funcion Testing in Dogs and Cats. The Veterinary Clinics of North America - Small Animal Practice. 22, 1087-1099.
21. NUNN, J. F. (1993) Nunn's Applied Respiratory Physiology. 4th edn. Butterworth Heinemann, Oxford. p 108.
22. PAVLIN, E. G. & HORNBEIN, T. F. (1986) Anesthesia and the control of ventilation. In: Handbook of Physiology. American Physiological Society, Bethseda, Maryland, pp 794-797.
23. PELLIGRINAO, D. A., RIEGLER, F. X. & ALBRECHT, R. F. (1988) The Comparative Ventilarory Effects of Morphine, Morphine-3-and Morphine-6-Glucuronide in the Awake Dog. Anesthesiology. 69, A812.
24. PELLIGRINO, D. A., PETERSON, R. D., HENDERSON, S. K. & ALBRECHT, R. F. (1989) Comparative Ventilatory Effects of Intravenous versus Fourth Cerebroventricular Infusion of Morphine Sulphate in the Unanaesthetized Dog. Anesthesiology. 71, 250-259.
25. PHILLIPSON, E. A., MURPHY, E. & KOZAR, L. F. (1976) Regulation of Respiration in Sleeping Dogs. Journal of Applied Physiology. 40, 688-693.
26. SCHLITT, S. C., SCHROETER, L. M., WILSON, J. E. & OLSEN, G. D. (1978) Methadone - Induced Respiratory Depression in the Dog: Comparison of Steady -State and Rebreathing Techniques and Correlation with Serum Drug Concentration. Journal of Pharmacology and Experimental Therapeutics. 207, 109-122.
27. SHORT, C. E. (1987) Pain, Analgesics and Related Medications. In Principles and Practice of Veterinary Anesthesia. Ed C. E. Short. Williams and Wilkins. Baltimore. pp 28-46.
28. STOBIE, D., CAYWOOD, D. D., ROZANSKI, E. A., BING, D. R., DHOKARIKAR, P., RAFFE, M. R., KANNAN, M. S., KING, V. L., HEGSTAD, R. L. & RANDALL, D. A. (1995) Evaluation of Pulmonary Function and Analgesia in Dogs After Intercostal Thoracotomy and Use of Morphine Administered Intramuscularly or Intrapleurally or Bupivacaine Administered Intrapleurally. American Journal of Veterinary Reseach. 56, 1098-1109.
29. TAYLOR, P. (1985) Analagesia in the Dog and Cat. In Practice. 7, 6-13.
30. THOMPSON, S. E. & JOHNSON, J. M. (1991). Analgesia in Dogs After Intercostal Thoracotomy: A Comparison of Morphine, Selective Intercostal Nerve Blocks and Interpleural Regional Analgesia with Bupivacaine. Veterinary Surgery. 20, 73-77.
31. TURNER, D. M., ILKIW, J. E., ROSE R. J. & WARREN, J. M. (1974) respiratory and Cardiovascular Effects of Five Drugs Used as Sedatives in the Dog. Australian Veterinary Journal. 50, 260-265.
32. WEINER, B. J. (1971) Statistical Principles in Experimental Design. 2nd edn. McGraw Hill Book Co., New York. pp 514-539.