Effect of a matrix metalloproteinase inhibitor (BB-1101) on nerve regeneration

Annals of the New York Academy of Sciences

Volumn 878, Issue , 1999, Pages 658-661

  Demestre, Maria ^a   Gregson, N A ^a   Smith, K J ^a   Miller, K M ^b   Gearing, A J ^b   Hughes, R A C ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b British Biotech Pharmaceuticals Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BB 1101; MATRIX METALLOPROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; INFLAMMATION; MALE; NERVE DEGENERATION; NERVE REGENERATION; NERVE STIMULATION; NEURITIS; NONHUMAN; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALIA;

EID: 0032815818     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07754.x     Document Type: Conference Paper

References (8)

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2. 2. Liedtke, W., B. Cannella, R.J. Mazzaccaro, J.M. Clements, K.M. Miller, K.W. Wucherpfennig, A.J. Gearing & C.S. Raine. 1998. Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors. Ann. Neurol. 44: 35-46.
3. 3. Kieseier, B.C., J.M. Clements, H.B. Pischel, G.M. Wells, K. Miller, A.J. Gearing & H.P. Hartung. 1998. Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barre syndrome. Ann. Neurol. 43: 427-434.
4. 4. Redford, E.J., K.J. Smith, N.A. Gregson, M. Davies, P. Hughes, A.J. Gearing, K. Miller & R.A.C. Hughes. 1997. A combined inhibitor of matrix metalloproteinase activity and tumour necrosis factor-alpha processing attenuates experimental autoimmune neuritis. Brain 120: 1895-1905.
5. 5. Hughes, P.M., G.M. Wells, J.M. Clements, A.J. Gearing, E.J. Redford, M. Davies, K.J. Smith, R.A.C. Hughes, M.C. Brown & K.M. Miller. 1998. Matrix metalloproteinase expression during experimental autoimmune neuritis. Brain 121:481-494.
6. 6. La Fleur, M., J.L. Underwood, D.A. Rappolee & Z. Werb. 1996. Basement membrane and repair of injury to peripheral nerve: defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1. J. Exp. Med. 184: 2311-2326.
7. 7. Hantai, D., J.S. Rao & B.W. Festoff. 1990. Rapid neural regulation of muscle urokinase-like plasminogen activator as defined by nerve crush. Proc. Natl. Acad. Sci. USA 87: 2926-2930.
8. 8. Kherif, S., M. Dehaupas, C. Lafuma, M. Fardeau & H.S. Alameddine. 1998. Matrix metalloproteinases MMP-2 and MMP-9 in denervated muscle and injured nerve. Neuropathol. Appl. Neurobiol. 24: 309-319.