Methotrexate nodulosis

Journal of Dermatology

Volumn 26, Issue 7, 1999, Pages 460-464

  Jang, Kyoung Ae ^a,b   Choi, Jee Ho ^a   Moon, Kee Chan ^a   Yoo, Bin ^a   Sung, Kyung Jeh ^a   Koh, Jai Kyoung ^a  

^a University of Ulsan   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

MTX nodulosis

Indexed keywords

HYDROXYCHLOROQUINE; METHOTREXATE;

ADULT; ARTICLE; CASE REPORT; DRUG EFFECT; FEMALE; HISTOPATHOLOGY; HUMAN; INFLAMMATORY CELL; MULTINUCLEAR CELL; PANNICULITIS; PATHOPHYSIOLOGY; RHEUMATOID ARTHRITIS; RHEUMATOID NODULE; SKIN NODULE; SUBCUTANEOUS NODULE;

EID: 0032814552     PISSN: 03852407     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1346-8138.1999.tb02027.x     Document Type: Article

References (21)

1. Segal R, Caspi D, Tishler M, Fishel B, Yaran M: Accelerated nodulosis and vasculitis during methotrexate therapy for rheumatoid arthritis, Arthritis Rheum, 31: 1182-1185, 1988.
2. Kerstens PJ, Boehbooms AM, Jeurissen ME, Fust JH, Assmann KJ, van de Putte LB: Accelerated nodulosis during low dose methotrexate therapy for rheumatoid arthritis. An analysis of ten cases, J Rhematol, 19: 867-871, 1992.
3. Combe B, Didry C, Gutierrez M, Anaya JM, Sany J: Accelerated nodulosis and systemic manifestations during methotrexate therapy for rheumatoid arthritis, Eur J Med, 2: 153-156, 1993.
4. Combe B, Gutierrez M, Anaya JM, Sany J: Possible efficacy of hydroxychloroquine on accelerated nodulosis during methotrexate therapy for rheumatoid arthritis, J Rheumatol, 20: 755-756, 1993.
5. Miyasaka N, Saito I, Uemura T, Kashiwazaki S: Augmented expression of inflammatory cytokines and adhesion molecules in accelerated nodulosis during methotrexate therapy, Ann Rheum Dis, 53: 480-481, 1994.
6. Abu-Shakra M, Nicol P, Urowitz MB: Accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate therapy, J Rheumatol, 21: 934-937, 1994.
7. Smith MD: Accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate therapy, J Rheumatol, 22: 2359-2360, 1995.
8. DiFrancesco L, Miller F, Greenwald RA: Detailed immunohistologic evaluation of a methotrexate-induced nodule, Arch Pathol Lab Med, 118: 1223-1225, 1994.
9. Muzaffer MA, Schneider R, Cameran BJ, Silverman ED, Laxer RM: Accelerated nodulosis during methotrexate therapy for juvenile rheumatoid arthritis, J Pediatr, 128: 698-700, 1996.
10. Falcini F, Taccetti G, Ermini M, et al: Methotrexate-associated apperance and rapid progression of rheumatoid nodules in systemic-onset juvenile rheumatoid arthritis. Arthritis Rheum, 40: 175-178, 1997.
11. Berris B, Houpt JB, Tenenbaum J: Accelerated nodulosis in a patient with psoriasis and arthritis during treatment with methotrexate, J Rheumatol, 22: 2359-2360, 1995.
12. Smith MD: Accelerated nodulosis in a patient with psoriasis and arthritis during treatment with methotrexate, J Rheumatol, 23: 2004, 1996.
13. Karan NE, Roger L, Hankins LL, Reveille JD: Rheumatoid nodulosis of the meninges, J Rheumatol, 21: 1960-1963, 1994.
14. Alarcon GS, Koopman WJ, McCarty MJ: Nonperipheral accelerated nodulosis in a methotrexate-treated rheumatoid arthritis patient, Arthritis Rheum, 36: 132-133, 1993.
15. Kaye BR, Kaye RL, Bobrove A: Rheumatoid nodules: Review of the spectrum of associated condition and proposal of a classification, with a report of 4 seronegative cases, Am J Med, 76: 279-292, 1984.
16. Araya JM, Diethelm L, Oritz LA, et al: Pulmonary involvement in rheumatoid arthritis. Semin Arthritis Rheum, 24: 242-254, 1995.
17. Jaworsky C: Connective tissue disease, in Elder D, Elenitsas R, Jaworsky C, Johnson, Jr B (eds): Lever's Histopathology of the Skin, 8th ed, Lippincott-Raven, Philadelphia, 1997, pp 847-887.
18. Fries JF, Singh G, Lenert L, Furts DE: Aspirin, hydroxychloroquine and hepatic enzyme abnormalities with methotrexate in rheumatoid arthritis, Arthritis Rheum, 33: 1611-1619, 1990.
19. Thompson RN: Is the appearance of rheumatoid nodules in a rheumatoid patient well controlled on methotrexate an indicator to stop the drug?, Br J Rheumatol, 31: 86, 1992.
20. Kerstens PJ, Boerbooms AM, van de Putte LB: Possible efficacy of hydroxychloroquine on accelerated nodulosis during methotrexate therapy for rheumatoid arthritis, J Rheumatol, 20: 756, 1993.
21. Merrill JT, Shen C, Schreibman D, et al: Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: A mechanism for methotrexate-induced nodulosis in rheumatoid arthritis, Arthritis Rheum, 40: 1308-1315, 1997.