The activity of caspase-3-like proteases is elevated during the development of colorectal carcinoma

Cancer Letters

Volumn 143, Issue 1, 1999, Pages 29-35

  Leonardos, L ^a   Butler, L M ^a   Hewett, P J ^a   Zalewski, P D ^a   Cowled, P A ^a  

^a QUEEN ELIZABETH HOSPITAL   (Australia)

Author keywords

Apoptosis; Caspase 3; Colorectal carcinoma; Fluorescence; Protease

Indexed keywords

CASPASE 3; PROTEINASE;

ADULT; AGED; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; FLUORESCENCE; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0032812997     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00176-7     Document Type: Article

References (28)

1. Potten C.S., Wilson J.W., Booth C. Regulation and significance of apoptosis in the stem cells of the gastrointestinal epithelium. Stem Cells. 15:1997;82-93.
2. Ikenaga M., Takano Y., Saegusa M., Ohtani Y., Hiki Y., Kakita A., Okayasu I. Apoptosis of colon cancers assessed by in situ DNA nick end labeling method. Pathol. Int. 46:1996;33-37.
3. Koike M. Significance of spontaneous apoptosis during colorectal tumorigenesis. J. Surg. Oncol. 62:1996;97-108.
4. Takano Y., Saegusa M., Ikenaga M., Mitomi H., Okayasu I. Apoptosis of colon cancer: comparison with Ki-67 proliferative activity and expression of p53. J. Cancer Res. Clin. Oncol. 122:1996;166-170.
5. Tatebe S., Ishida M., Kasagi N., Tsujutani S., Kaibara N., Ito H. Apoptosis occurs more frequently in metastatic foci than in primary lesions of human colorectal carcinomas: analysis by terminal-deoxynucleotidyl-transferase-mediated dUTP-biotin nick end labeling. Int. J. Cancer. 65:1996;173-177.
6. Arai T., Kino I. Role of apoptosis in modulation of the growth of human colorectal tubular and villous adenomas. J. Pathol. 176:1995;37-44.
7. Baretton G.B., Diebold J., Christoforis G., Vogt M., Müller C., Dopfer K., Schneiderbanger K., Schmidt M., Löhrs U. Apoptosis and immunohistochemical bcl-2 expression in colorectal adenomas and carcinomas; aspects of carcinogenesis and prognostic significance. Cancer. 77:1996;255-264.
8. Hawkins N., Lees J., Hargrave R., O'Connor T., Meagher A., Ward R. Pathological and genetic correlates of apoptosis in the progression of colorectal neoplasia. Tumor Biol. 18:1997;146-156.
9. Nakamura T., Sakai T., Nariya S. Cell death in colorectal polyps as evaluated by in situ 3′-tailing reaction and its relationship to BCL-2 expression. Pathol. Int. 45:1995;721-728.
10. Bedi A., Pasricha P.J., Akhtar A.J., Barber J.P., Bedi G.C., Giardiello F.M., Zehnbauer B.A., Hamilton S.R., Jones R.J. Inhibition of apoptosis during development of colorectal cancer. Cancer Res. 55:1995;1811-1816.
11. Moss S.F., Scholes J.V., Holt P.R. Abnormalities of epithelial apoptosis in multistep colorectal neoplasia demonstrated by terminal deoxyuridine nick end labeling. Dig. Dis. Sci. 41:1996;2238-2247.
12. Fernandes-Alnemri T., Litwack G., Alnemri E.S. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J. Biol. Chem. 269:1994;30761-30764.
13. Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., Munday N.A., Raju S.M., Smulson M.E., Yamin T.-T., Yu V.L., Miller D.K. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 376:1995;37-43.
14. Whitehead R.H., Macrae F.A., St-John D.J.B., Ma J. A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer. J. Natl. Cancer Inst. 74:1985;759-765.
15. Medina V., Edmonds B., Young G.P., James R., Appleton S., Zalewski P.D. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. Cancer Res. 57:1997;3697-3707.
16. Yuan J.Y., Shaham S., Ledoux S., Ellis H.M., Horvitz H.R. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell. 75:1993;641-652.
17. Hugunin M., Quintal L.J., Mankovich J.A., Ghayar T. Protease activity of in vitro transcribed and translated Caenorhabditis elegans cell death gene (ced-3) product. J. Biol. Chem. 271:1996;3517-3522.
18. Xue D., Shaham S., Horvitz H.R. The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease. Genes Dev. 10:1996;1073-1083.
19. Tewari M., Quan L.T., O'Rourke K., Desnoyers S., Zehg Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/CPP32 beta, a mammalian homologue of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81:1995;801-809.
20. Han Z., Hendrickson E.A., Bremner T.A., Wyche J.H. sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro. J. Biol. Chem. 272:1997;13432-13436.
21. Gurtu V., Kain S.R., Zhang G. Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal. Biochem. 251:1997;98-102.
22. Talanian R.V., Quinlan C., Trautz S., Hackett M.C., Mankovich J.A., Banach D., Ghayur T., Brady K.D., Wong W.W. Substrate specificities of caspase family proteases. J. Biol. Chem. 272:1997;9677-9682.
23. Tiso N., Pallavicini A., Muraro T., Zimbello R., Apolloni E., Valle G., Lanfranchi G., Danieli G.A. Chromosomal localization of the human genes, CPP32, Mch2, Mch3, and Ich-1, involved in cellular apoptosis. Biochem. Biophys. Res. Commun. 225:1996;983-989.
24. Arai T., Maruyama K., Kamo T., Sugimura H. Origin of intraepithelial apoptotic cells in human colorectal adenomas. Pathol. Int. 47:1997;333-335.
25. Denis F., Rheaume E., Aouad S.M., Alam A., Sekaly R.P., Cohen L.Y. The role of caspases in T cell development and the control of immune responses. Cell. Mol. Life Sci. 54:1998;1005-1019.
26. Glinsky G.V., Glinsky V.V. Apoptosis and metastasis: a superior resistance of metastatic cancer cells to programmed cell death. Cancer Lett. 101:1996;43-51.
27. Glinsky G.V., Glinsky V.V., Ivanova A.B., Hueser C.J. Apoptosis and metastasis: increased apoptosis resistance of metastatic cancer cells is associated with the profound deficiency of apoptosis execution mechanisms. Cancer Lett. 115:1997;185-193.
28. Shimizu S., Eguchi Y., Kamiike W., Itoh Y., Hasegawa J., Yamabe K., Otsuki Y., Matsuda H., Tsujimoto Y. Induction of apoptosis as well as necrosis by hypoxia and predominant prevention of apoptosis by Bcl-2 and Bcl-XL. Cancer Res. 56:1996;2161-2166.