Differential display analysis can reveal patterns of gene expression in immortalised hepatoma cells which are similar to those observed in young adult but not old adult liver cells

Cancer Letters

Volumn 143, Issue 1, 1999, Pages 45-50

  Charlton, M A ^a,b   Merry, B J ^c   Goyns, M H ^a  

^a UNIVERSITY OF SUNDERLAND   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Differential display; Gene expression; Hepatoma; Immortalisation; Liver

Indexed keywords

AGING; ARTICLE; CELL IMMORTALIZATION; DNA SEQUENCE; GENE EXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL;

EID: 0032812908     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00173-1     Document Type: Article

References (21)

1. Campisi J. The biology of replicative senescence. Eur. J. Cancer. 33:1998;703-709.
2. Wynford-Thomas D. Proliferative lifespan checkpoints: cell-type specificity and influence on tumour biology. Eur. J. Cancer. 33:1998;716-726.
3. Goyns M.H., Charlton M.A., Dunford J.E., Lavery L.W., Merry B.J., Salehi M., Simoes D.C.M. Differential display analysis of gene expression indicates that age-related changes are restricted to a small cohort of genes. Mech. Ageing Dev. 101:1998;73-90.
4. Liang P., Pardee B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 257:1992;967-971.
5. Salehi M., Hodgkins M.A., Merry B.J., Goyns M.H. Age-related changes in gene expression revealed in the rat brain by differential display. Experientia. 52:1996;888-891.
6. Utans U., Liang P., Wyner L.R., Karnovsky M.J., Russell M.E. Chronic cardiac rejection - identification of 5 upregulated genes in transplanted hearts by differential messenger RNA display. Proc. Natl Acad. Sci. USA. 91:1994;6463-6467.
7. Kar S., Carr B.I. Differential display and cloning of messenger RNAs from the late phase of rat liver regeneration. Biochem. Biophys. Res. Commun. 212:1995;21-26.
8. Watson J.B., Margulies J.E. Differential cDNA screening strategies to identify novel stage specific proteins in the developing mammalian brain. Dev. Neurosci. 15:1993;77-86.
9. Uchiyama C.M., Zhu J., Carroll R.S., Leon S.P., Black P.M. Differential display of messenger ribonucleic acid: a useful technique for analysing differential gene expression in human brain tumors. Neurosurgery. 37:1995;464-470.
10. Koecher O., Cheresh P., Brown L.F., Lee S.W. Identification of a novel gene, selectively up-regulated in human carcinomas using the differential display technique, Clin. Cancer Res. 1:1995;1209-1215.
11. Huang L.R., Hsu H.C. Cloning and expression of CD24 gene in human hepatocellular carcinoma: a potential early tumor marker gene correlates with p53 mutation and tumor differentiation. Cancer Res. 55:1995;4717-4721.
12. Mok S.C., Wong K.K., Chan R.K.W., Lau C.C., Tsao S.W., Knapp R.C., Berkowitz R.S. Molecular cloning of differentially expressed genes in human epithelial ovarian cancer. Gynaecol. Oncol. 52:1994;247-252.
13. Groningen J.J.M., Bloemmers H.P.J., Swart G.W.M. Identification of melanoma inhibitory activity and other differentially expressed messenger RNAs in human melanoma cell lines with different metastatic capacity by messenger RNA differential display. Cancer Res. 55:1995;6237-6243.
14. Carter D., Goepel J.R., Winship P.R., Goyns M.H. Identification of different patterns of gene expression in low and high grade non-Hodgkin's lymphomas by differential display. Leuk. Lymph. 1999;. in press.
15. Thompson E.B., Tomkins M.G., Curran J.F. Induction of tyrosine α-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line. Biochemistry. 56:1966;296-303.
16. San R.H.C., Shimada T., Maslansky C.J., Kreiser D.M., Laspia M.F., Rice J.M., Williams G.M. Growth characteristics and enzyme activities in a survey of transformation markers in adult rat liver epithelium-like cell cultures. Cancer Res. 39:1979;4441-4448.
17. Strous G.J.A.M., Lodish H.F. Intracellular transport of secretory and membrane proteins in hepatoma cells infected by vesicular stromatitis virus. Cell. 22:1980;709-717.
18. Holehan A.M., Merry B.J. The experimental manipulation of ageing by diet. Biol. Rev. 61:1986;329-368.
19. Liang P., Zhu W., Zhang X., Guo Z., O'Connell R.P., Averboukh L., Wang F., Pardee A.B. Differential display using one based anchored oligo dT primers. Nucleic Acids Res. 22:1994;5763-5764.
20. Liang P., Pardee A.B. Recent advances in differential display. Curr. Opin. Immunol. 7:1995;274-280.
21. 35S as a label for differential display of eukaryotic messenger RNA. Science. 267:1995;1186-1187.