Structural and cytotoxic study of new Pt(II) and Pd(II) complexes with the bi-heterocyclic ligand mepirizole

Journal of Inorganic Biochemistry

Volumn 75, Issue 3, 1999, Pages 205-212

  Onoa, G B ^a   Moreno, V ^a   Font Bardia, M ^a   Solans, X ^a   Perez J M ^b   Alonso, C ^b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Cytotoxic activity; Mepirizole; Pd(II) bi heterocyclic complex; Pd mepirizole crystal structure; Pt(II) bi heterocyclic complex

Indexed keywords

DICHLORO 4 METHOXY 2 (5 METHOXY 3 METHYLPYRAZOL 1 YL) 6 METHYLPYRIMIDINE PALLADIUM(II); EPIRIZOLE; PALLADIUM COMPLEX; PLATINUM COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; GEOMETRY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; SPECTROSCOPY; STRUCTURE ANALYSIS; TUMOR CELL LINE; X RAY DIFFRACTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE, TRANSFORMED; CERCOPITHECUS AETHIOPS; CRYSTALLOGRAPHY, X-RAY; EPIRIZOLE; HL-60 CELLS; HUMANS; JURKAT CELLS; LIGANDS; MICE; PALLADIUM; PLATINUM; SPECTRUM ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

EID: 0032811722     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-0134(99)00089-6     Document Type: Article

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