Stereoselective conjugate addition of alkyl groups to (S)-4-(tert- butyldimethylsilyloxy)-2-phenylsulfonyl-2-cyclopentenone by means of trialkylaluminum reagents

Synlett

Volumn , Issue 8, 1999, Pages 1313-1315

  Yakura, Takayuki ^a   Tanaka, Kenji ^a   Iwamoto, Miki ^a   Nameki, Masatake ^a   Ikeda, Masazumi ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Aluminum; Conjugate addition reaction; Cyclopentanone; Stereoselectivity; Sulfone

Indexed keywords

4 (TERT BUTYLDIMETHYLSILYLOXY) 3 ALKYL 2 PHENYLSULFONYLCYCLOPENTANONE; ALUMINUM; CYCLOPENTANONE DERIVATIVE; REAGENT; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DIASTEREOISOMER; ISOMERISM; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS;

EID: 0032811141     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-2823     Document Type: Article

References (29)

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28. An intriguing alternative to this mechanism would involve the formation of the chelated intermediate D. Unfortunately, the cis-selectivity of the ester 1b cannot be explained through a similar intermediate E.
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