Enantioselective Cu-catalyzed 1,4-addition of Me3Al to a 4,4-disubstituted cyclohexa-2,5-dienone: Novel effect of trialkylsilylOTf on enantioselectivity

Tetrahedron Asymmetry

Volumn 7, Issue 4, 1996, Pages 993-996

  Takemoto, Yoshiji ^a   Kuraoka, Satoru ^b   Hamaue, Naoko ^a   Iwata, Chuzo ^a  

^a OSAKA UNIVERSITY   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXENE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; ENANTIOMER; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 0029873869     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/0957-4166(96)00100-0     Document Type: Article

References (30)

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25. b) The two phenolic oxazolines 3d and 3e were prepared from the corresponding nitriles accroding to literature methods: Balm, C.; Weickhardt, K.; Zehnder, M.; Ranff, T. Chem. Ber. 1991, 124, 1173-1180; Jhonstone, R. A. W.; Rose, M. E. Tetrahedoron 1979, 35, 2169-2173. The 2-(2′-n-butylphenyl)-4-isopropyloxazoline 3f was prepared from 3d by the reaction with n-butylmagnesum chloride: Meyers, A. I.; Gabel, R.; Mihelich, E. D. J. Org. Chem. 1978, 43, 1372-1379.
26. b) The two phenolic oxazolines 3d and 3e were prepared from the corresponding nitriles accroding to literature methods: Balm, C.; Weickhardt, K.; Zehnder, M.; Ranff, T. Chem. Ber. 1991, 124, 1173-1180; Jhonstone, R. A. W.; Rose, M. E. Tetrahedoron 1979, 35, 2169-2173. The 2-(2′-n-butylphenyl)-4-isopropyloxazoline 3f was prepared from 3d by the reaction with n-butylmagnesum chloride: Meyers, A. I.; Gabel, R.; Mihelich, E. D. J. Org. Chem. 1978, 43, 1372-1379.
27. 3).
28. 3)]. The details of the X-ray crystallographic analysis will be described in a full paper in near future.
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