Chronic myeloid leukemia with expression of ALL-type BCR/ABL transcript: A case-report and review of the literature

Leukemia Research

Volumn 23, Issue 9, 1999, Pages 851-854

  Solves, P ^a   Bolufer, P ^b   Lopez J A ^a   Barragan E ^b   Bellod, L ^a   Ferrer, S ^c   Rosell, A ^c   Lerma, E ^a   Cervera, J ^a   De La Rubia, J ^a   Sanz, G F ^a   Sanz Alonso, M Á ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^b Department of Clinical Pathology ^*  (Spain)

^c HOSPITAL UNIVERSITARIO DR PESET   (Spain)

Author keywords

Acute lymphoblastic leukemia; BCR ABL transcript; Chronic myeloid leukemia

Indexed keywords

ALPHA INTERFERON; ANTILEUKEMIC AGENT; BUSULFAN; CYTARABINE; ETOPOSIDE; GRANULOCYTE COLONY STIMULATING FACTOR; HYDROXYUREA; IDARUBICIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; CHRONIC MYELOID LEUKEMIA; FEMALE; GENETIC TRANSCRIPTION; HUMAN; PRIORITY JOURNAL;

ADULT; FEMALE; FUSION PROTEINS, BCR-ABL; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOID, CHRONIC; RNA, MESSENGER;

EID: 0032809364     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(99)00099-5     Document Type: Article

References (17)

1. Rowley J.D. A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa stainning. Nature. 243:1973;290.
2. Chissoe S.L., Bodenteich A., Wang Y.F., Wang Y.P., Burian D., Clifton S.W., Crabtree J., Freeman A. et al. Sequence and analysis of the human abl gene, the bcr gene, and regions involved in the Philadelphia chromosomal translocations. Genomics. 27:1995;67.
3. Selleri L., von Lindern M., Hermans A., Meijer D., Torelli G., Grosveld G. Chronic myeloid leukemia may be associated with several bcr-abl transcripts including the acute lymphoid leukemia-type 7 Kb transcript. Blood. 75:1990;1146-1153.
4. Zaccaria A., Tassinari A., Testoni N., Lauria F., Tura S., Algeri R., Guerrasio A., Rosso C., Saglio G. Alternative BCR/ABL transcripts in chronic myeloid leukemia. Blood. 76:1990;1663-1665.
5. Sawyers C.L., Timson L., Kawasaki E.S., Clark S.S., Witte O.N., Champlin R. Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction. Proc. Natl. Acad. Sci. USA. 87:1990;563-567.
6. Nakamura Y., Hirosawa S., Aoki N. Consistent involvement of the 3′ half of the first BCR intron in adult Philadelphia-positive leukemia without M-bcr rearrangement. Br. J. Haematol. 83:1993;53-57.
7. Guo J.Q., Hirsch-Ginsberg C.F., Xian Y.M., Stass S.A., Champlin R.E., Giralt S.A., McCredie K.B., Campbell M.L., Arlinghaus R.B. Acute lymphoid leukemia molecular phenotype in a patient with benign-phase chronic myelogenous leukemia. Hematol. Pathol. 7:1993;91-106.
8. Melo J., Myint H., Galton D.A.G., Goldman J.M. P190 bcr-abl chronic myeloid leukemia: the missing link with chronic myelomonocytic leukaemia? Leukemia. 8:1994;208-211.
9. Kunieda Y., Okabe M., Kurosawa M., Itaya T., Kakinuma M., Miyazaki T. Chronic myeloid leukemia presenting ALL-type BCR/ABL transcript. Ann. Hematol. 69:1994;189-193.
10. Costello R.T., Gabert J., Brunel V., Sainty D., Arnoulet C., Mozziconacci M.J., Camerlo J., Perret C., Gastaut J.A., Bouabdallah R., Lafage-Pochilatoff M. Minor breakpoint cluster region (m-BCR) positive chronic myeloid leukaemia with an acute lymphoblastic leukaemia onset: a case report. Br. J. Haematol. 91:1995;428-430.
11. Kirk J.A., Radich J., Edmands S., Lee A., Vandevanter D.R., Reems J.A., Bryant E.M. Unusual expression of mRNA typical of Philadelphia positive acute lymphoblastic leukemia detected in chronic myelogenous leukemia. Am. J. Hematol. 52:1996;129-134.
12. Yamaguchi H., Inokuchi K., Shinohara T., Dan K. Extramedullary presentation of chronic myelogenous leukemia with p190 bcr/abl transcripts. Cancer Genet. Cytogenet. 102:1998;74-77.
13. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
14. Cross N.C.P., Melo J.V., Feng L., Goldman J.M. An optimized multiplex polymerase chain reaction (PCR) for detection of BCR-ABL fusion mRNAs in haematological disorders. Leukemia. 8:1994;186-189.
15. Cross N.C.P., Hughes T., Feng L., O'Shea P., Bungey J., Marks D.I., Ferrant A., Martrat P., Goldman J.M. Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: correlations with acute graft-versus-host disease and relapse. Br. J. Haematol. 84:1993;67-74.
16. Melo J. The diversity of BCR/ABL fusion proteins and their relantionship to leukemia phenotype. Blood. 88:1996;2375-2384.
17. Saglio G., Pane F., Gottardi E. et al. Consistent amounts of acute leukemia p190 bcr/abl transcripts are expressed by chronic myelogenous leukemia patients at diagnosis. Blood. 87:1996;1075-1080.