Treatment with inverse agonists enhances baseline atrial contractility in transgenic mice with chronic beta2-adrenoceptor activation

British Journal of Pharmacology

Volumn 127, Issue 5, 1999, Pages 1099-1104

  Nagaraja, Savitha ^a   Iyer, Srinivas ^a   Liu, Xiushi ^a   Eichberg, Joseph ^a   Bond, Richard A ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

adrenoceptors; G protein coupled receptor kinase; G proteins; Inverse agonists; Isoprenaline; Left atria; Transgenic mice

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ALPRENOLOL; BETA 2 ADRENERGIC RECEPTOR; CARVEDILOL; CELL PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; MEMBRANE PROTEIN; PROPRANOLOL; PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART ATRIUM CONTRACTILITY; HEART MUSCLE TENSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; TRANSGENE; WESTERN BLOTTING;

ADRENERGIC BETA-AGONISTS; ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GTP-BINDING PROTEINS; ISOPROTERENOL; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; PROPANOLAMINES; RECEPTORS, ADRENERGIC, BETA-2;

EID: 0032808091     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702645     Document Type: Article

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