Immunotherapeutic potential of dendritic cells generated in long term stroma-dependent cultures

Cancer Biotherapy and Radiopharmaceuticals

Volumn 14, Issue 4, 1999, Pages 263-276

  O'Neill, Helen C ^a   Jonas, N ^a   Wilson, H ^a   Ni, K ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Cytotoxic T cells; Dendritic cells; Immunotherapy; Long term culture; Tumour immunity

Indexed keywords

ADOPTIVE TRANSFER; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CELL CULTURE; CELL MIGRATION; CELLULAR IMMUNITY; DENDRITIC CELL; IMMUNOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN LYMPHOCYTE; STROMA CELL;

EID: 0032807753     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.1999.14.263     Document Type: Article

References (49)

1. Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 1991;9: 271.
2. Hamblin TJ. From dendritic cells to tumour vaccines. Lancet 1996;347: 705.
3. Steinman RM. Dendritic cells and immune-based therapies. Exp Hematol. 1996;24: 859.
4. Abdel-Wahab Z, DeMatos P, Hester D, Da Dong X, and Siegler H. Human dendritic cells, pulsed with either melanoma tumor cell lysates or the gp100 peptide, induce pairs of T-cell cultures with similar phenotype and lytic activity. Cell Immunol 1998;186: 63.
5. DeMatos P, Abdel-Wahab Z, Vervaert C, and Seigler H. Vaccination with dendritic cells inhibits the growth of hepatic metastases in B6 mice. Cell Immunol 1998;185: 65.
6. Hsu FJ, Benike C, Fagnoli F, Liles TM, Czerwinski D, Taidi B, Engelman E, and Levy R. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med 1996;2: 52.
7. Knight SC, Hunt R, Dore C, and Medawar PB. Influence of dendritic cells on tumor growth. Proc Natl Acad Sci USA. 1985;82: 4495.
8. Liu B, Podack ER, Allison JP, and Malek TR. Generation of primary tumor-specific CTL in vitro to immunogenic and poorly immunogenic mouse tumors. J Immunol 1996;156: 1117.
9. Sallusto F and Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin4 and downregulated by tumor necrosis factor-α. J Exp Med 1994;179: 1109.
10. Yang S, Darrow TL, Vervaert CE, and Seigler HF. Immunotherapeutic potential of tumor antigen-pulsed and unpulsed dendritic cells generated from murine bone marrow. Cell Immunol. 1997;179: 84.
11. Celluzzi CM, Mayordomo JI, Storkus WJ, Lotze MT, and Falo LD. Peptide-pulsed dendritic cells induce antigen-specific, CTL-mediated protective tumor immunity. J Exp Med. 1996;183: 283.
12. Flamand V, Sornasse T, Thielemans K, Damanet C, Bakkus M, Bazin H, Tielemans F, Leo O, Urbain J, and Moser M. Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo. Eur J Immunol 1994;24: 605.
13. Ribas A, Butterfield LH, McBride WH, Jilani SM, Bui LA, Vollmer CM, Lau R, Dissette VB, Hu B, Chen AY, Glaspy JA, and Economou JS. Genetic immunization for the melanoma antigen MART-1/Melan-A using recombinant adenovirus-transduced murine dendritic cells. Cancer Res 1997;57: 2865.
14. Yotnda P, Firat H, Garcia-Pons F, Garcia Z, Gourru G, Verdant J, Lemonnier F, Leblond V, and Langlade-Demoyen P. Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia. J Clin Invest. 1998; 101: 2290.
15. Zitvogel L, Mayordomo JI, Tjandrawan T, DeLeo AB, Clarke MR, and Lotze MT. Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines. J Exp Med 1996;183: 87.
16. Boczkowski D, Nair SK, Snyder D, and Gilboa E. Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. J Exp Med 1996; 184: 465.
17. Condon C, Watkins SC, Celluzzi CM, Thompson K, and Falo LD. DNA-based immunization by in vivo transfection of dendritic cells. Nat Med. 1996;2: 1122.
18. Manickan E, Kanangat S, Rouse RJ, Yu Z, and Rouse BT. Enhancement of immune responses to naked DNA vaccine by immunization with transfected dendritic cells. J Leukoc Biol 1997;61: 125.
19. Paglia P, Chiodoni C, Rodolfo M, and Colombo MP. Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo. J Exp Med 1996;183: 317.
20. + progenitors. Adv Exp Med Biol. 1997; 417: 15.
21. Hadzantonis, M. and O'Neill, H.C. Dendritic cell Immunotherapy for Melanoma. Cancer Biotherapy 1999;14(1):11-22.
22. Steinman RM and Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med 1973;137: 1142.
23. Steinman RM, Gutchinov B, Witmer MD, and Nussenzweig MC. Dendritic cells are the principal stimulators of the primary mixed leukocyte reaction in mice. J Exp Med 1983;157: 613.
24. Steinman RM, Kaplan G, Witmer MD, and Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro. J Exp Med 1979;149: 1.
25. McLellan AD, Sorg RV, Williams LA, and Hart DN. Human dendritic cells activate T lymphocytes via a CD40: CD40 ligand-dependent pathway. Eur J Immunol 1996;26: 1204.
26. Suss G and Shortman K. A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis. J Exp Med 1996;183: 1789.
27. Knight SC, Farrant J, Bryant A, Edwards AJ, Burman S, Lever A, Clarke J, and Webster AD. Non-adherent, low-density cells from human peripheral blood contain dendritic cells and monocytes, both with veiled morphology. Immunol 1986;57: 595.
28. Vremec D, Leischke GJ, Dunn AR, Robb L, Metcalf D, and Shortman K. The influence of granulocyte/ macrophage colony stimulating factor on dendritic cell levels in mouse lymphoid organs. Eur J Immunol 1997;27: 40.
29. Inaba K, Inaba M, Romani N, Aya H, Degushi M, Ikehara S, Muramatsu S, and Steinman RM. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/ macrophage colony-stimulating factor. J Exp Med 1992;176: 1693.
30. Romani N, Gruner S, Brang D, Kampgen E, Lenz A, Trockenbacher B, Konwalinka G, Fritsch PO, Steinman PM, and Schluer G. Proliferating dendritic cell progenitors in human blood. J. Exp. Med 1994;180: 83.
31. + Hematopoietic Progenitor cells. Immunobiol 1998;198: 501.
32. Winzler C, Rovere P, Zimmermann VS, Davoust J, Rescigno M, Citterio S, and Ricciardi-Castagnoli P. Checkpoints and functional stages in DC maturation. Adv Exp Med Biol 1997;417: 59.
33. + hemopoietic progenitors. J Immunol 1996;157: 1499.
34. + hemopoietic progenitors. J Immunol 1996;157: 1499.
35. Ni K and O'Neill HC. Long-term stromal cultures produce dendritic-like cells. Br J Haematol 1997;97: 710.
36. Ni K and O'Neill HC. Haemopoiesis in long-term stroma-dependent cultures from lymphoid tissue: Production of cells with myeloid/dendritic cell characteristics. In vitro Cell Mol Biol 1998;34: 298.
37. Ni K and O'Neill HC. Spleen stromal cells support haemopoiesis and in vitro growth of dendritic cells from bone marrow. Br J Haematol, in press. (1999)
38. Lieberman M, Decleve A, Ricciardi-Castagnoli P, Boniver J, Finn OJ, and Kaplan HS. Establishment, characterisation and virus expression of cell lines derived from radiation- and virus-induced lymphomas of C57BL/Ka mice. Int J Cancer 1979;24: 168.
39. Gorer PA and Amos DB. Passive immunity in mice against C57BL leukosis EL4 by means of isoimmune serum. Cancer Res 1959;16: 338.
40. Dunn TB and Potter M. A transplantable mast cell neoplasm in the mouse. J Natl Cancer Inst 1957;18: 587.
41. Weston SA and Parish CR. New fluorescent dyes for lymphocyte migration studies. J Immunol Methods 1990;133: 87.
42. Wunderlich J and Shearer G. Induction and measurement of cytotoxic T lymphocyte activity. In Current Protocols in Immunology. JE Coligan, AM Kruisbeck, DH Margulies, EM Sheuach, and W Strober. John Wiley and Sons, New York, pg 3.11.1 (1997).
43. Sanchez-Madrid F, Simon P, Thompson S and Springer TA. Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med 1983;158: 586.
44. Austyn JM. New insights into the mobilization and phagocytic activity of dendritic cells. J Exp Med 1996;183: 1287.
45. Cohen PJ, Cohen PA, Rosenberg SA, Katz SI, and Mule JJ. Murine epidermal Langerhans cells and splenic dendritic cells present tumor-associated antigens to primed T cells. Eur J Immunol 1994;24: 315.
46. Girolomoni G and Ricciardi-Castagnoli P. Dendritic cells hold promise for immunotherapy. Immunol Today 1997;18: 102.
47. Blake J, Johnston J, Hellstrom K, Marquardt H, and Chen L. Use of combinatorial peptide libraries to construct functional mimics of tumor epitopes recognised by MHC Class I-restricted cytolytic T lymphocytes. J Exp Med 1996;184: 121.
48. Banchereau J and Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392: 245.
49. Kimber I and Cumberbatch M. Langerhans cell migration: Initiation and regulation. In Heidrun, M. (ed.) The immune functions of epidermal Langerhans cells pp. 103-119. R. G. Landes Co., Austin, Texas, USA (1995).