Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders

Carcinogenesis

Volumn 20, Issue 7, 1999, Pages 1231-1233

  Beckman, L E ^a   Van Landeghem, G F ^a   Sikstrom C ^a   Wahlin, A ^a   Markevarn B ^a   Hallmans, G ^a   Lenner, P ^a   Athlin, L ^a   Stenling, R ^a   Beckman, L ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFERRIN RECEPTOR;

ARTICLE; BREAST CANCER; CANCER RISK; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; GENETIC SUSCEPTIBILITY; GENOTYPE; HEMOCHROMATOSIS; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RECEPTOR GENE;

ALLELES; BREAST NEOPLASMS; COLORECTAL NEOPLASMS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEMOCHROMATOSIS; HETEROZYGOTE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; MALE; MEMBRANE PROTEINS; MULTIPLE MYELOMA; MUTATION; ODDS RATIO; RECEPTORS, TRANSFERRIN; RISK ASSESSMENT;

EID: 0032804816     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.7.1231     Document Type: Article

References (36)

1. Weinberg, E.D. (1996) The role of iron in cancer. Eur. J. Cancer Prev., 5, 19-36.
2. McCord, J.M. (1992) Iron and oxidative balance. In Lauffer, R.B. (ed.) Iron and Human Disease. CRC Press, Boca Raton, FL, pp. 509-518.
3. de Sousa, M. (1989) The immunology of iron overload. In De Sousa, M. and Brock, J.H. (eds) Iron in Immunity, Cancer and Inflammation. John Wiley & Sons, Chichester, UK, pp. 247-258.
4. Weinberg, E.D. (1984) Iron withholding: a defence against infection and neoplasia. Physiol. Rev., 64, 65-102.
5. Bergeron, R.J., Streiff, R.R. and Elliott, G.T. (1985) Influence of iron on in vivo proliferation and lethality of L 1210 cells. J. Nutr., 115, 369-374.
6. Bowman, B.H., Yang, F. and Adrian, G.S. (1988) Transferrin: evolution and genetic regulation of expression. Adv. Genet., 25, 1-38.
7. Kamboh, M.I. and Ferrell, R.E. (1987) Human transferrin polymorphism. Hum. Hered., 37, 65-81.
8. Sikström, C., Beckman, L., Hallmans, G. and Asplund, K. (1993) Transferrin types, iron-binding capacity and body iron stores. Hum. Hered., 43, 337-341.
9. Van Landeghem, G.F., Sikström, C., Beckman, L.E., Adolfsson, R. and Beckman, L. (1998) Transferrin C2, metal binding and Alzheimer's disease. NeuroReport, 9, 177-179.
10. Neckers, L.M. (1984) Transferrin receptors regulate proliferation of normal and malignant β cells. Curr. Top. Microbiol. Immunol, 113, 62-68.
11. Cazzola, M., Bergamaschi, G., Dezza, L. and Arioso, P. (1990) Manipulations of cellular iron metabolism for modulating normal and malignant cell proliferation: achievements and prospects. Blood, 75, 1903-1919.
12. Reizenstein, P. (1991) Iron, free radicals and cancer. Med. Oncol. Tumor Pharmacother, 8, 229-233.
13. Kemp, J.D., Smith, K.M., Mayer, J.M., Gomez, F., Thorson, J.A. and Naumann, P.W. (1992) Effects of anti-transferrin receptor antibodies on the growth of neoplastic cells. Pathobiology, 60, 27-32.
14. Evans, P. and Kemp, J. (1997) Exon/intron structure of the human transferrin gene. Gene, 199, 123-131.
15. Van Landeghem, G.F., Beckman, L.E., Sikström, C., Saha, N., Kucinskas, V. and Beckman, L. (1998) New DNA polymorphisms define ethnically distinct haplotypes in the human transferrin receptor gene. Hum. Hered., 48, 245-250.
16. Feder, J.N., Gnirke, A., Thomas, W. et al. (1996) A novel MHC class-1 like gene is mutated in patients with hereditary haemochromatosis. Nature Genet., 13, 399-408.
17. Jouanolle, A.M., Gaudou, G., Jézéquel, P. et al. (1996) Haematomachrosis and HLA. Nature Genet., 14, 251-252.
18. Jazwinska, E.C., Cullen, L.M., Busfield, F., Pepper, W.R., Webb, S.I., Powell, L.W., Morris, C.P. and Walsh, T.P. (1996) Haemochromatosis and HLA. Nature Genet., 14, 249-250.
19. Risch, N. (1997) Haemochromatosis, HFE and genetic complexity. Nature Genet., 17, 375-376.
20. Merryweather-Clarke, A.T., Worwood, M., Parkinson, L., Mattock, C., Pointon, J.J., Shearman, J.D. and Robson, K.J. (1998). The effect of HFE mutations on serum ferritin and transferrin saturation in the Jersey population. Br. J. Haematol., 45, 146-149.
21. Adams, P.C. (1994) Prevalence of abnormal iron studies in heterozygotes for hereditary haemochromatosis: an analysis of 255 heterozygotes. Am. J. Hematol, 45, 146-149.
22. Bradbear, T.A., Bain, C., Siskind, V., Schofield, F.D., Webb, S. Axelsen, E.M., Halliday, J.W., Bassett, M.L. and Powell, L.W. (1985) Cohort study of internal malignancy in genetic hemochromatosis and other chronic nonalcoholic liver diseases. J. Natl Cancer Inst., 75, 81-84.
23. Niederau, C., Fischer, R., Pürschel, A., Stremmal, W., Häussinger, D. and Strohmeyer, G. (1996) Long-term surival in patients with hereditary hemochromatosis. Gastroenterology, 110, 1107-1119.
24. Nelson, R.L., Davis, F.G., Persky, V. and Becker, E. (1995) Risk of neoplastic and other diseases among people with heterozygosity for hereditary hemochromatosis. Cancer, 76, 875-879.
25. Feder, J.N., Penny, D.M., Irrinki, A., Lee, V.K., Lebrón, J.A., Watson, N., Tsuchihashi, Z., Sigal, E., Bjorkman, P.J. and Schatzman, R.C. (1998) The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding. Proc. Natl Acad. Sci. USA, 95, 1472-1477.
26. Van Landeghem, G.F., Beckman L.E., Wahlin, A., Markevärn, B. and Beckman, L. (1998) Interaction between hemochromatosis and transferrin receptor genes in multiple myeloma. Lancet, 352, 1285-1286.
27. Hann, H.-W.L., Stahlhut, N.W. and Blumberg, B.S. (1988) Iron nutrition and tumor growth: decreased growth in iron-deficient mice. Cancer Res., 48, 4168-4170.
28. Själander, A., Birgander, R., Hallmans, G., Cajander, S., Lenner, P., Athlin, L., Beckman, G. and Beckman, L. (1996) p53 polymorphisms and haplotypes in breast cancer. Carcinogenesis. 17, 1313-1316.
29. Själander, A., Birgander, R., Athlin, L., Stenling, R., Rutegård, J., Beckman, L. and Beckman, G. (1995) p53 germ line haplotypes associated with increased risk for colorectal cancer. Carcinogenesis, 16, 1461-1464.
30. Birgander, R., Själander, A., Rannug, A., Alexandrie, A.-K., Ingelman Sundberg, M., Seidegård, J., Tornling, G., Beckman, G. and Beckman L. (1995) p53 polymorphisms and haplotypes in lung cancer. Carcinogenesis, 16, 2233-2236.
31. Själander, A., Birgander, R., Kivelä, A. and Beckman, G. (1995) p53 polymorphisms and haplotypes in different ethnic groups. Hum. Hered. 45, 144-149.
32. Cunningham, B.A., Wang, J.L., Berggard, I. and Peterson, P.A. (1973) The complete amino acid sequence of beta-2-microglobulin. Biochemistry, 12, 4811-4821.
33. Munro, H.N., Aziz, N., Leibold, E.A., Murray, M., Rogers, J., Vass, J.K. and White, K. (1988) The ferritin genes; structure, expression and regulation. Ann. N. Y. Acad. Sci., 526, 113-123.
34. Klausner, R.D., Rouault, T.A. and Harford, J.B. (1993) Regulating the fate of mRNA: the control of cellular iron metabolism. Cell, 72, 19-28.
35. Lee, P.L., Gelbart, T., West, C., Halloran, C. and Beutler, E. (1998) The human Nramp 2 gene: characterization of the gene structure, alternative splicing, promotor region and polymorphisms. Blood Cells Mol. Dis., 24, 199-215.
36. Tsuchihashi, Z., Hansen, S.L., Quintana, L., Kronmal, G.S., Mapa, F.A., Feder, J.N. and Wolff, R.K. (1998) Transferrin receptor mutation analysis in hereditary hemochromatosis patients. Blood Cells Mol. Dis., 24, 317-321.