Development of a high metastatic orthotopic model of human renal cell carcinoma in nude mice: Benefits of fragment implantation compared to cell-suspension injection

Clinical and Experimental Metastasis

Volumn 17, Issue 3, 1999, Pages 265-270

  An, Zili ^a   Jiang, Ping ^a   Wang, Xiaoen ^a   Moossa, A R ^b   Hoffman, Robert M ^a,b  

^a ANTICANCER INC   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Angiogenesis; Metastasis; Orthotopic fragment transplant; Renal cancer

Indexed keywords

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INVASION; CANCER MODEL; CANCER TRANSPLANTATION; CELL SUSPENSION; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; LIVER METASTASIS; LUNG METASTASIS; LYMPH NODE METASTASIS; METASTASIS POTENTIAL; NONHUMAN; NUDE MOUSE; TUMOR CELL LINE;

ADULT; ANIMALS; CARCINOMA, RENAL CELL; CELL DIVISION; CELL TRANSPLANTATION; DISEASE MODELS, ANIMAL; HUMANS; KIDNEY NEOPLASMS; LIVER NEOPLASMS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; SUBRENAL CAPSULE ASSAY; SURVIVAL RATE;

EID: 0032799678     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006654600095     Document Type: Article

References (26)

1. Marutsuka K, Hasui Y, Asada Y et al. Effects of suramin on metastatic ability, proliferation, and production of urokinase-type plasminogen activator and plasminogen activator inhibitor type 2 in human renal cell carcinoma cell line SN12C-PM6. Clin Exp Metastasis 1995; 13: 116-22.
2. Morikawa K, Walker SM, Jessup JM, Fidler IJ. In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinoma implanted into nude mice. Cancer Res 1988; 48: 1943-8.
3. Nakajima M, Morikawa K, Fabra A et al. Influence of organ microenvironment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. J Natl Cancer Inst 1990; 82: 1890-8.
4. Vieweg J, Heston WDW, Gilboa E, Fair WR. An experimental model simulating local recurrence and pelvic lymph node metastasis following orthotopic induction of prostate cancer. Prostate 1994; 24: 291-8.
5. Singh RK, Bucana CD, Gutman M et al. Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells. Am J Pathol 1994; 145: 365-74.
6. Naito S, Walker SM, von Eschenbach AC, Fidler IJ. Evidence for metastasis heterogencity of human renal cell carcinoma. Anticancer Res 1988; 8: 1163-7.
7. Burgers JK, Marshall FF, Isaacs JT. Enhanced anti-tumor effects of recombinant human tumor necrosis factor plus VP-16 on metastatic renal cell carcinoma in a xenograft model. J Urol 1989; 142: 160-4.
8. Naito S, von Eschenbach AC, Fidler IJ. Different growth pattern and biologic behavior of human renal cell carcinoma implanted into different organs of nude mice. JNCI 1987; 78: 377-85.
9. Fu X, Besterman JM, Monosov A and Hoffman RM. Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens. Proc Natl Acad Sci USA 1991; 88: 9345-9.
10. Fu X, Gundagni F and Hoffman RM. A metastatic nude-mouse model of human pancreatic cancer constructed orthotopically from histologically intact patient specimens. Proc Natl Acad Sci USA 1992; 89: 5645-9.
11. Hoffman RM. Patient-like models of human cancer in mice. Current Perspectives Molecular Cellular Oncol 1992: 1(B): 311-26.
12. Wang X, Fu X, Hoffman RM. A new patient-like metastatic model of human lung cancer constructed orthotopically with intact tissue via thoractomy in immunodeficient mice. Int J Cancer 1992; 51: 992-5.
13. Astoul P. Colt HG, Wang X, Hoffman RM. Metastatic human pleural ovarian cancer model constructed by orthotopic implantation of fresh histologically intact patient carcinoma in nude mice. Anticancer Res 1993; 13: 1999-2002.
14. An Z, Wang X, Kubota T et al. A clinical nude mouse metastatic model for highly malignant human pancreatic cancer. Anticancer Res 1996; 16: 627-32.
15. Kopf-Maier P, Jackel M. Proliferation behavior of xenografted human tumors: A flow cytometric study. Anticancer Res 1988; 8: 1355-60.
16. Kopf-Maier P. Dying and regeneration of human tumor cells after heterotransplantation to athymic mice. Histol Histopathol 1986; 1: 383-90.
17. An Z, Wang X, Geller J et al. Surgical orthotopic implantation allows high lung and lymph node metastatic expression of human prostate carcinoma cell line PC-3 in nude mice. Prostate 1998; 34: 169-74.
18. Fu X, Hoffman RM. Human RT-4 bladder carcinoma is highly metastatic in nude mice and comparable to rasH-transformed RT-4 when orthotopically onplanted as histologically intact tissue. Int J Cancer 1992; 51: 989-91.
19. Fu X, Theodorescu D, Kerbel RS, Hoffman RM. Extensive multiorgan metastasis following orthotopic onplamation of histologically-intact human bladder carcinoma tissue in nude mice. Int J Cancer 1991; 49: 938-9.
20. Furukawa T, Fu X, Kubota T et al. Nude mouse metastatic models of human stomach cancer constructed using orthotopic implantation of histologically intact tissue. Cancer Res 1993; 53: 1204-8.
21. Cowen SE, Bibby MC, Double JA. Characterisation of the vasculature within a murine adenocarcinoma growing in different sites to evaluate the potential of vascular therapies. Acta Oncologica 1995; 34: 357-60.
22. Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989; 339: 58-61.
23. Folkman J. Angiogenesis. In: Verstraete M, Vermylen J, Lijnan R, Arnout J (eds) Thombosis and haemostasis. Leuven: Leuven University Press, 1987; 583-96.
24. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 324 1991; 1-8.
25. Togo S, Shimada H, Kubota T, Moossa AR, Hoffman RM. Host organ specifically determines cancer progression. Cancer Res. 1995; 55: 681-4.
26. Naito S, von Eschenbach AC, Giavazzi R, Fidler IJ, Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice. Cancer Res 1986; 46: 4109-15.