Mode of action of anhydrofulvic acid against Candida utilis ATCC 42402 under acidic condition

Journal of Antibiotics

Volumn 52, Issue 7, 1999, Pages 628-634

  Fujita, Ken Ichi ^a   Nagamine, Yasuko ^a   Ping, Xu ^a   Taniguchi, Makoto ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ANHYDROFULVIC ACID; CYTOCHROME C; FULVIC ACID; GLUCOSE; LEUCINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; SUCCINIC ACID; UNCLASSIFIED DRUG;

ACIDITY; AMINO ACID METABOLISM; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA UTILIS; CELL RESPIRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PENETRATION; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; MINIMUM INHIBITORY CONCENTRATION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PH; PRIORITY JOURNAL; RESPIRATORY CHAIN;

EID: 0032796760     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.52.628     Document Type: Article

References (23)

1. DEAN, F. M.; R. A. EADE, R. MOUBASHER & A. ROBERTSON: The chemistry of Fungi. Part XXVII. The structure of fulvic acid from Carpenteles brefeldianum. J. Chem. Soc. 1957: 3497-3510, 1957
2. OXFORD, A. E.; H. RAISTRICK & P. SIMONART: CXXXIX. Studies in the biochemistry of micro-organisms. XLIV. Fulvic acid, a new crystalline yellow pigment, a metabolic product of P. griseofulvum dierckx, P flexuosum dale and P. brefeldianum dodge. Biochem. J. 29: 1102-1115, 1935
3. SAKAI, T.; A. ICHIHARA & S. SAKAMURA: Isolation of fulvic acid from Cercospora beticola. Agric. Biol. Chem. 45: 1275-1276, 1981
4. SINGH, K.; S. SUN & C. VÈZINA: Rapamycin (AY-22,989), A new antifungal antibiotic IV. Mechanism of action. J. Antibiotics 32: 630-644, 1979
5. BESSON, F.; F. PEYPOUX, M. J. QUENTIN & G. MICHEL: Action of antifungal peptidolipids from Bacillus subtilis on the cell membrane of Saccharomyces cerevisiae. J. Antibiotics. 37: 172-177, 1984
6. HAYASHI, T.; O. YAMAMOTO, H. SAKAKI, H. OKAZAKI & A. KAWAGUCHI: Inhibition of fatty acid synthesis by the antibiotic thiolactomycin. J. Antibiotics 37: 1456-1461, 1984
7. HAMAMOTO, T.; T. UOZUMI & T. BEPPU: Leptomycins A and B, new antifungal antibiotics. III. Mode of action of leptomycin B on Schizosaccharomyces pombe. J. Antibiotics 38: 1573-1579, 1985
8. PING, X.; Y. AKEDA, K. FUJITA, T. TANAKA & M. TANIGUCHI: The mode of action of AKD-2C, antifungal antibiotic from Streptomyces sp. OCU-42815. J. Antibiotics 51: 275-279, 1998
9. TANIGUCHI, M.; Y. YANO, E. TADA, K. IKENISHI, S. OI, H. HARAGUCHI, K. HASHIMOTO & I. KUBO: Mode of action of polygodial, an antifungal sesquiterpene dialdehyde. Agric. Biol. Chem. 52: 1409-1414, 1988
10. DUBOIS, M.; K. A. GILLES, J. K. HAMILTON, P. A. REBERS & F. SMITH: Colorimetric method for determination of sugars and related substances. Anal. Chem. 28: 350-356, 1956
11. BRADFORD, M. M.: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 74: 248-254, 1976
12. UEKI, M. & M. TANIGUCHI: The mode of action of UK-2A and UK-3A , novel antifungal antibiotics from Streptomyces sp. 517-02. J. Antibiotics 50: 1052-1057, 1997
13. BRUINENBERG, P. M.; J. P. VAN DIJKEN, J. G. KUENEN & W. A. SCHEFFERS: Critical parameters in the isolation of mitochondria from Candida utilis grown in continuous culture. J. Gen. Microbiol. 131: 1035-1042, 1983
14. BRUINENBERG, P. M.; J. P. VAN DIJKEN & W. A. SCHEFFERS: An enzymatic analysis of NADPH production and consumption in Candida utiltis. J. Gen. Microbiol. 129: 965-971, 1983
15. UDEN, N. VAN & H. BUCKLEY: Discussion of the genera of asporogenpus yeasts not belonging to the Sporobolomycetaceae. Genus 2. Candida Berkhout. In The yeasts. A taxonomic study, Ed., J. LODDER, pp. 891-1082, North-Holland Publishing Company, Amsterdam, Holland, 1970
16. YAMAGUCHI, M.; S. KATAYAMA, T. TODOROKI & T. WATANABE: Total synthesis of fulvic acid. J. Chem. Soc., Chem. Commn. 23: 1565-1566, 1984
17. YAMAGUCHI, M.; S. KATAYAMA, T. TODOROKI & T. WATANABE: Studies on the synthesis of heterocyclic compounds containing benzopyrone. Part 5. Total synthesis of fulvic acid. J. Chem. Soc. Perkin Trans. I. 2: 389-394, 1984
18. SOFOS, J. N. & F. F. BUSTA: Sorbates. In Antimicrobials in Food. Ed., A. L. BRANEN & P. M. DAVIDSON, pp. 141-175, Dekker, New York, 1983
19. KREBS, H. A.; D. WIGGINS, S. SOLE & F. BEDOYA: Studies on the mechanism of the antifungal action of benzoate. Biochem. J. 214: 657-663, 1983
20. KUBO, I. & S. H. LEE: Potentiation of antifungal activity of sorbic acid. J. Agric. Food. Chem. 46: 4052-4055, 1998
21. SCHEFFLER, I. E.: Molecular genetics of succinate: quinone oxidoreductase in eukaryotes. Prog. Nucleic. Acid. Res. Mol. Biol. 60: 267-315, 1998
22. WARTH, A. D.: Transport of benzoic and propanoic acids by Zygosaccharomyces bailii. J. Gen. Microbiol. 135: 1383-1390, 1989
23. IGLESIAS, R.; J. M. FERRERAS, F. J. ARIAS, R. MUNOZ, M. ANGELES-ROJO & T. GIRBES: Effect of L-azetidine-2-carboxylic acid on the activity of the general amino acid permease from Saccharomyces cerevisiae var. ellipsoideus. Arch. Microbiol. 155: 320-324, 1991