Longitudinal variation in hepatitis C virus (HCV) viraemia and early course of HCV infection after liver transplantation for HCV cirrhosis: The role of different immunosuppressive regimens

Gut

Volumn 45, Issue 3, 1999, Pages 427-434

  Papatheodoridis, G V ^a   Barton, S G R G ^a   Andrew, D ^a   Clewley, G ^a   Davies, S ^a   Dhillon, A P ^a   Dusheiko, G ^a   Davidson, B ^a   Rolles, K ^a   Burroughs, A K ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Grading score; HCV genotype; HCV RNA; Immunosuppression; Liver transplantation; Staging score

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; PREDNISOLONE; TACROLIMUS;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CLINICAL ARTICLE; DISEASE COURSE; DRUG EFFECT; EARLY DIAGNOSIS; FEMALE; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; LIVER TRANSPLANTATION; LONGITUDINAL STUDY; MALE; PRIORITY JOURNAL; SCORING SYSTEM; VIREMIA; VIRUS INFECTION;

EID: 0032795779     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.45.3.427     Document Type: Article

References (39)

1. 1 Wright TL, Donegan E, Hsu HH, et al. Recurrent and acquired hepatitis C viral infection in liver transplant recipients. Gastroenterology 1992;103:317-22.
2. 2 Sallie R, Cohen AT, Tibbs CJ, et al. Recurrence of hepatitis C following orthotopic liver transplantation: a polymerase chain reaction and histological study. J Hepatol 1994;21: 536-42.
3. 3 Gane EJ, Portmann BC, Naoumov NV, et al. Long-term outcome of hepatitis C infection after liver transplantation. N Engl J Med 1996;334:815-20.
4. 4 Boker KHW, Dalley G, Bahr MJ, et al. Long-term outcome of hepatitis C virus infection after liver transplantation. Hepatology 1997;25:203 10.
5. 5 Gane EJ, Naoumov NV, Qian K-P, et al. A longitudinal analysis of hepatitis C virus replication following liver transplantation. Gastroenterology 1996;110:167-77.
6. 6 Gretch DR, Bacchi CE, Corey L, et at. Persistent hepatitis C virus infection after liver transplantation: clinical and virological features. Hepatology 1995;22:1 9.
7. 7 Feray C, Gigou M, Samuel D, et al. Influence of the genotypes of hepatitis C virus on the severity of recurrent liver disease after liver transplantation, Gastroemerology 1995;108:1088-96.
8. 8 Fukumoto T, Berg T, Ku Y, et al. Viral dynamics of hepatitis C early after orthotopic liver transplantation: evidence for rapid turnover of scrum virions. Hepatology 1996;24:1351 4.
9. 9 Feray C, Gigou M, Samuel D, et al. The course of hepatitis C virus infection after liver transplantation. Hepatology 1994;20:1137 43.
10. 10 Chazouilleres O, Kim M, Combs C, et al. Quantitation of hepatitis C virus RNA in liver transplant recipients. Gastroenterology 1991;106:994 9.
11. 11 Crespo J, Carte B, Lozano JL, et al. Hepatitis C virus recurrence after liver transplantation: relationship to anri-HCV core IgM, genotype, and level of viremia. Am J Gasitroenterol 1997;92:1458 62.
12. 12 Collier J, Heathcote J, Hepatitis C viral infection in the immunosuppressed patient. Hepatology 1998;27:2-6.
13. 13 Charlton M, Seaberg E, Wiesner R, et al. Predictors of patient and graft survival following liver transplantation for hepatitis C. Hepatology 1998;28:823-30.
14. 14 Poynard T, Bedossa P, Opolon P, et al. Natural history of liver fihrosis progression in patients with chronic hepatitis C. Lancet 1997;349:825-32.
15. 15 Papatheodoridis GV, Patch D, Dusheiko GM, et al. The outcome of hepatitis C virus infection after liver transplantation Is it influenced by the type of immuno-suppression? J Hepatol 1999;30:731-8.
16. 16 Magrin S, Craxi A, Fabiano C, et al. Hepatitis C viremia in chronic liver disease: relationship to interferon-α or corticosteroid treatment. Hepatology 1994;19:273 9.
17. 17 Rosen HR, Shackleton CR, Higa L, et al. Use nf OKT3 is associated with early and severe recurrence of hepatitis C after liver transplantation. Am J Gastroenterol 1997;92: 1453 7.
18. 18 Berenguer M, Prieto M, Cordoba J, et al. Early development of chronic active hepatitis in recurrent hepatitis C after liver transplantation: association with treatment of rejection. J Hepatol 1998;28:756 63.
19. 19 Freeman RB, Tran S, Lee YM, et al. Serum hepatitis C RNA titers after liver transplantation are not correlated with immunosuppression or hepatitis. Transplantation 1996;61:542 6.
20. 20 Zervos XA, Weppler D, Fragulidis GP, et al. Comparison of tacrolimus with microemulsion cyclosporin as primary immunosuppression in hepatitis C patients after liver transplantation. Transplantation 1998;65:1044-6.
21. 21 Fraser GM, Grammoustianos K, Reddy J, et al. Long-term immunosuppression without corticosteroids after orthotopic liver transplantation: a positive therapeutic aim. Liver Transplant Surg 1996;2:411 17.
22. 22 Kidd IM, Fox JC, Pillay D, et al. Provision of prognostic information in immunocompromised patients by routine application of the polymerase chain reaction for cytomegalovirus. Transplantation 1993;56:867 71.
23. 23 Kissmeyer NF, Svejgaard A, Hauge M. The HLA system defined with lymphocytotoxic and platelet antibodies in relation to kidney transplantation. Transplant Proc 1969;1: 357-61.
24. 24 Young KKY, Resnick RM, Myers TW. Detection of hepatitis C virus hy a combined reverse transcription-polymerase chain reaction assay. J Clin Microb 1993;31:882 6.
25. 25 Stuyver L, Rossau R, Wyseur A, et al. Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay. J Gen Virol 1993;74:1093-102.
26. 26 Simmonds P, Smith DB,McOmish F, et al. Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions. J Gen Virol 1994;75:1053-61.
27. 27 Gupta SD, Hudson M, Burroughs AK, et al. Grading of cellular rejection after orthotopic liver transplantation. Hepatology 1995;21:46 57.
28. 28 Bianchi L, De Groote J, Desmet VJ, et al. Acute and chronic hepatitis revisited. Lancet 1977;ii:911-19.
29. 29 Ishak K, Baptista A, Bianchi L, et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995;22:696 9.
30. 30 Sheiner PA, Schwartz ME, Mor E, et al. Severe or multiple rejection episodes are associated with early recurrence of hepatitis C after orthotopic liver transplantation. Hepatology 1995;21:30 4.
31. 31 Di Martino V, Saurini F, Samuel D, et al. Long-term longitudinal study of intrahepatic hepatitis C virus replication after liver transplantation. Hepatology 1997;26:1343 50.
32. 32 Diepolder HM, Zachoval R, Hoffmann RM, et al. Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet 1995;346:100-7.
33. 33 Missale G, Bertoni R, Lamonaca V, et al. Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell mediated immune response. J Clin Invest 1906;98:706 14.
34. 34 Tur-Kaspa R, Burk RD, Shaul Y, et al. Hepatitis B virus DNA contains a glucocorticoid-responsive elememt. Proc Natl Acad Sci USA 1986;83:1627-31.
35. 35 Rosen HR, Gretch DR, Oehlke M, et al. Timing and severity of initial hepatitis C recurrence as predictors of long-term liver allograft injury. Transplantation 1998;65: 1178 82.
36. 36 Rimola A, Restrepo JC, Quinto L, et al. Incidence and predictive factors of severe HCV recurrence after liver transplantation [abstract]. J Hepatol 1998;28(suppl 1):4.
37. 37 Shuhart MC, Bronner MP, Gretch DR, et al. Histological and clinical outcome after liver transplantation for hepatitis C. Hepatology 1997;26:1646 52.
38. 38 Gordon FD, Poterucha JJ, Germer J, et al. Relationship between hepatitis C genorype and severity of recurrent hepatitis C after liver transplantation. Transplantation 1997; 63:1419-23.
39. 39 Zhou S, Terrauli NA, Ferrell L, et al. Severity of liver disease in liver transplantation recipients with hepatitis C virus infection: relationship to genotype and level of viremia. Hepatology 1996;24:1041 6.