The free energies for mutating S27 and W79 to alanine in streptavidin and its biotin complex: The relative size of polar and nonpolar free energies on biotin binding

Proteins: Structure, Function and Genetics

Volumn 36, Issue 4, 1999, Pages 471-473

  Dixon, Richard W ^a,b   Kollman, Peter ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BASF Bioresearch Corporation   (United States)

Author keywords

Free energy calculations; Molecular dynamics; Protein binding

Indexed keywords

BIOTIN; STREPTAVIDIN;

ARTICLE; ENERGY CONSUMPTION; MATHEMATICAL ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING;

ALANINE; AMINO ACID SUBSTITUTION; BIOTIN; COMPUTER SIMULATION; ELECTROSTATICS; MUTATION; PROTEIN BINDING; SERINE; STREPTAVIDIN; THERMODYNAMICS; TRYPTOPHAN;

EID: 0032793576     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(19990901)36:4<471::AID-PROT11>3.0.CO;2-6     Document Type: Article

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