메뉴 건너뛰기




Volumn 19, Issue 9, 1999, Pages 6140-6153

Identification by in vivo genomic footprinting of a transcriptional switch containing NF-κB and Sp1 that regulates the IκBα promoter

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1;

EID: 0032793299     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.19.9.6140     Document Type: Article
Times cited : (42)

References (62)
  • 1
    • 0028892099 scopus 로고
    • In vivo regulation of interleukin-2 receptor alpha gene transcription by the coordinated binding of constitutive and inducible factors in human primary T cells
    • Algarté, M., P. Lécine, R. Costello, A. Plet, D. Olive, and J. Imbert 1995. In vivo regulation of interleukin-2 receptor alpha gene transcription by the coordinated binding of constitutive and inducible factors in human primary T cells. EMBO J. 16:5060-5072.
    • (1995) EMBO J. , vol.16 , pp. 5060-5072
    • Algarté, M.1    Lécine, P.2    Costello, R.3    Plet, A.4    Olive, D.5    Imbert, J.6
  • 2
    • 0033052233 scopus 로고    scopus 로고
    • Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factor
    • Alroy, I., L. Soussan, R. Seger, and Y. Yarden. 1999. Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factor. Mol. Cell. Biol. 19:1961-1972.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1961-1972
    • Alroy, I.1    Soussan, L.2    Seger, R.3    Yarden, Y.4
  • 3
    • 0027519680 scopus 로고
    • Phosphatidylcholine hydrolysis activates NF-κB and increases human immunodeficiency virus replication in human monocytes and T lymphocytes
    • Arenzana-Seisdedos, F., B. Fernandez, I. Dominguez, J. M. Jacqué, D. Thomas, M. T. Diaz-Meco, J. Moscat, and J. L. Virelizier. 1993. Phosphatidylcholine hydrolysis activates NF-κB and increases human immunodeficiency virus replication in human monocytes and T lymphocytes. J. Virol. 67:6596-6604.
    • (1993) J. Virol. , vol.67 , pp. 6596-6604
    • Arenzana-Seisdedos, F.1    Fernandez, B.2    Dominguez, I.3    Jacqué, J.M.4    Thomas, D.5    Diaz-Meco, M.T.6    Moscat, J.7    Virelizier, J.L.8
  • 4
    • 0030973394 scopus 로고    scopus 로고
    • Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity
    • Armstrong, S. A., D. A. Barry, R. W. Leggett, and C. R. Mueller. 1997. Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity. J. Biol. Chem. 272:13489-13495.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13489-13495
    • Armstrong, S.A.1    Barry, D.A.2    Leggett, R.W.3    Mueller, C.R.4
  • 5
    • 0030271387 scopus 로고    scopus 로고
    • NF-κB: Ten years after
    • Baeuerle, P. A., and D. Baltimore. 1996. NF-κB: ten years after. Cell 87:13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 6
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141-179.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 7
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin, A. S., Jr. 1996. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649-681.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-681
    • Baldwin A.S., Jr.1
  • 9
    • 17544374742 scopus 로고    scopus 로고
    • The role of the C-terminal domain of IκBα in protein degradation and stability
    • Beauparlant, P., R. Lin, and J. Hiscott. 1996. The role of the C-terminal domain of IκBα in protein degradation and stability. J. Biol. Chem. 271: 10690-10696.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10690-10696
    • Beauparlant, P.1    Lin, R.2    Hiscott, J.3
  • 10
    • 0027332498 scopus 로고
    • The IκB proteins: Multifunctional regulators of Rel/NF-κB transcription factors
    • Beg, A. A., and S. Baldwin, Jr. 1993. The IκB proteins: multifunctional regulators of Rel/NF-κB transcription factors. Genes Dev. 7:2064-2070.
    • (1993) Genes Dev. , vol.7 , pp. 2064-2070
    • Beg, A.A.1    Baldwin S., Jr.2
  • 11
    • 0026783210 scopus 로고
    • IκB interacts with the nuclear localization sequence of the subunits of NF-κB: A mechanism for cytoplasmic retention
    • Beg, A. A., S. M. Ruben, R. I. Scheinman, S. Haskill, C. A. Rosen, and A. S. Baldwin, Jr. 1992. IκB interacts with the nuclear localization sequence of the subunits of NF-κB: a mechanism for cytoplasmic retention. Genes Dev. 6:1899-1913.
    • (1992) Genes Dev. , vol.6 , pp. 1899-1913
    • Beg, A.A.1    Ruben, S.M.2    Scheinman, R.I.3    Haskill, S.4    Rosen, C.A.5    Baldwin A.S., Jr.6
  • 12
    • 0029163601 scopus 로고
    • Retrovirus-mediated transfer of nuclear factor-κB subunit genes modulates IκBα and interferon β expression
    • Bitar, R., P. Beauparlant, R. Lin, P. Pitha, and J. Hiscott. 1995. Retrovirus-mediated transfer of nuclear factor-κB subunit genes modulates IκBα and interferon β expression. Cell Growth Differ. 6:965-976.
    • (1995) Cell Growth Differ. , vol.6 , pp. 965-976
    • Bitar, R.1    Beauparlant, P.2    Lin, R.3    Pitha, P.4    Hiscott, J.5
  • 15
    • 0027462682 scopus 로고
    • Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκBα
    • Brown, K., S. Park, T. Kanno, G. Franzoso, and U. Siebenlist. 1993. Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκBα. Proc. Natl. Acad. Sci. USA 90:2532-2536.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2532-2536
    • Brown, K.1    Park, S.2    Kanno, T.3    Franzoso, G.4    Siebenlist, U.5
  • 16
    • 0029146930 scopus 로고
    • Signal-induced site-specific phosphorylation targets IκBα to the ubiquitin-proteasome pathway
    • Chen, Z., J. Hagler, V. J. Palombella, F. Melandri, D. Scherer, D. Ballard, and T. Maniatis. 1995. Signal-induced site-specific phosphorylation targets IκBα to the ubiquitin-proteasome pathway. Genes Dev. 9:1586-1597.
    • (1995) Genes Dev. , vol.9 , pp. 1586-1597
    • Chen, Z.1    Hagler, J.2    Palombella, V.J.3    Melandri, F.4    Scherer, D.5    Ballard, D.6    Maniatis, T.7
  • 18
    • 0027245086 scopus 로고
    • Cytokine-inducible expression in endothelial cells of an IκBα-like gene is regulated by NF-κB
    • de Martin, R., B. Vanhove, Q. Cheng, E. Hofer, V. Csizmadia, H. Winkler, and F. H. Bach. 1993. Cytokine-inducible expression in endothelial cells of an IκBα-like gene is regulated by NF-κB. EMBO J. 12:2773-2779.
    • (1993) EMBO J. , vol.12 , pp. 2773-2779
    • De Martin, R.1    Vanhove, B.2    Cheng, Q.3    Hofer, E.4    Csizmadia, V.5    Winkler, H.6    Bach, F.H.7
  • 19
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato, J. A., M. Hayakawa, D. M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388:548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 20
    • 0027446270 scopus 로고
    • The c-rel protooncogene product represses NF-κB p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus
    • Doerre, S., P. Sista, S.-C. Sun, D. W. Ballard, and W. C. Greene. 1993. The c-rel protooncogene product represses NF-κB p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 90:1023-1027.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1023-1027
    • Doerre, S.1    Sista, P.2    Sun, S.-C.3    Ballard, D.W.4    Greene, W.C.5
  • 21
    • 0028983432 scopus 로고
    • The PEST-like sequence of IκBα is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers
    • Ernst, M. K., L. L. Dunn, and N. R. Rice. 1995. The PEST-like sequence of IκBα is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers. Mol. Cell. Biol. 15:872-882.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 872-882
    • Ernst, M.K.1    Dunn, L.L.2    Rice, N.R.3
  • 22
    • 0026708394 scopus 로고
    • Independent modes of transcriptional activation by the p50 and p65 subunits of NF-κB
    • Fujita, T., G. P. Nolan, S. Ghosh, and D. Baltimore. 1992. Independent modes of transcriptional activation by the p50 and p65 subunits of NF-κB. Genes Dev. 6:775-787.
    • (1992) Genes Dev. , vol.6 , pp. 775-787
    • Fujita, T.1    Nolan, G.P.2    Ghosh, S.3    Baltimore, D.4
  • 23
    • 0026532763 scopus 로고
    • Effects of different DNA polymerases in ligation-mediated PCR: Enhanced genomic sequencing and in vivo footprinting
    • Garrity, P. A., and B. Wold. 1992. Effects of different DNA polymerases in ligation-mediated PCR: enhanced genomic sequencing and in vivo footprinting. Proc. Natl. Acad. Sci. USA 89:1021-1025.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1021-1025
    • Garrity, P.A.1    Wold, B.2
  • 24
    • 0027650908 scopus 로고
    • The activity of a 70 kilodalton IκB molecule identical to the carboxyl terminus of the p105 NF-κB precursor is modulated by protein kinase A
    • Gerondakis, S., N. Morrice, I. B. Richardson, R. Wettenhall, J. Fecondo, and R. J. Grumont. 1993. The activity of a 70 kilodalton IκB molecule identical to the carboxyl terminus of the p105 NF-κB precursor is modulated by protein kinase A. Cell Growth Differ. 4:617-627.
    • (1993) Cell Growth Differ. , vol.4 , pp. 617-627
    • Gerondakis, S.1    Morrice, N.2    Richardson, I.B.3    Wettenhall, R.4    Fecondo, J.5    Grumont, R.J.6
  • 29
    • 0028170124 scopus 로고
    • Three NF-κB sites in the IκB-α promoter are required for induction of gene expression by TNFα
    • Ito, C. Y., A. G. Kazantsev, and A. S. Baldwin, Jr. 1994. Three NF-κB sites in the IκB-α promoter are required for induction of gene expression by TNFα. Nucleic Acids Res. 22:3787-3792.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 3787-3792
    • Ito, C.Y.1    Kazantsev, A.G.2    Baldwin A.S., Jr.3
  • 30
    • 0028986046 scopus 로고
    • Domain organization of IκBα and the sites of interaction with NF-κB p65
    • Jaffray, E., K. M. Wood, and R. T. Hay. 1995. Domain organization of IκBα and the sites of interaction with NF-κB p65. Mol. Cell. Biol. 15:2166-2172.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2166-2172
    • Jaffray, E.1    Wood, K.M.2    Hay, R.T.3
  • 31
    • 0032571002 scopus 로고    scopus 로고
    • Inducible expression of IκBα repressor mutants interferes with NF-κB activity and HIV-1 replication in Jurkat T cells
    • Kwon, H., N. Pelletier, C. DeLuca, P. Genin, S. Cisternas, R. Lin, M. A. Wainberg, and J. Hiscott. 1998. Inducible expression of IκBα repressor mutants interferes with NF-κB activity and HIV-1 replication in Jurkat T cells. J. Biol. Chem. 273:7431-7440.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7431-7440
    • Kwon, H.1    Pelletier, N.2    DeLuca, C.3    Genin, P.4    Cisternas, S.5    Lin, R.6    Wainberg, M.A.7    Hiscott, J.8
  • 32
    • 0025001941 scopus 로고
    • Cell-specific differences in activation of NF-κB regulatory elements of human immunodeficiency virus and beta interferon promoters by tumor necrosis factor
    • Lacoste, J., M. D'Addario, A. Roulston, M. A. Wainberg, and J. Hiscott. 1990. Cell-specific differences in activation of NF-κB regulatory elements of human immunodeficiency virus and beta interferon promoters by tumor necrosis factor. J. Virol. 64:4726-4734.
    • (1990) J. Virol. , vol.64 , pp. 4726-4734
    • Lacoste, J.1    D'Addario, M.2    Roulston, A.3    Wainberg, M.A.4    Hiscott, J.5
  • 33
    • 0025643362 scopus 로고
    • A general method for rapid site-directed mutagenesis using the polymerase chain reaction
    • Landt, O., H. P. Grunert, and U. Hahn. 1990. A general method for rapid site-directed mutagenesis using the polymerase chain reaction. Gene 96:125-128.
    • (1990) Gene , vol.96 , pp. 125-128
    • Landt, O.1    Grunert, H.P.2    Hahn, U.3
  • 34
    • 0027979264 scopus 로고
    • Differential regulation of the c-myc oncogene promoter by the NF-κB rel family of transcription factors
    • La Rosa, F. A., J. W. Pierce, and G. E. Sonenshein. 1994. Differential regulation of the c-myc oncogene promoter by the NF-κB rel family of transcription factors. Mol. Cell. Biol. 14:1039-1044.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1039-1044
    • La Rosa, F.A.1    Pierce, J.W.2    Sonenshein, G.E.3
  • 35
    • 0027453548 scopus 로고
    • Promoter analysis of the gene encoding the IκB-α/MAD 3 inhibitor of NF-κB: Positive regulation by members of the rel/NF-κB family
    • Le Bail, O., R. Schmidt-Ullrich, and A. Israel 1993. Promoter analysis of the gene encoding the IκB-α/MAD 3 inhibitor of NF-κB: positive regulation by members of the rel/NF-κB family. EMBO J. 12:5043-5049.
    • (1993) EMBO J. , vol.12 , pp. 5043-5049
    • Le Bail, O.1    Schmidt-Ullrich, R.2    Israel, A.3
  • 36
    • 0028151080 scopus 로고
    • NF-κB/Rel family members are physically associated phosphoprotein
    • Li, C.-C., M. Korner, D. K. Ferris, E. Chen, R.-M. Dai, and D. L. Longo. 1994. NF-κB/Rel family members are physically associated phosphoprotein. Biochem. J. 303:499-506.
    • (1994) Biochem. J. , vol.303 , pp. 499-506
    • Li, C.-C.1    Korner, M.2    Ferris, D.K.3    Chen, E.4    Dai, R.-M.5    Longo, D.L.6
  • 37
    • 0029670085 scopus 로고    scopus 로고
    • Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability
    • Lin, R., P. Beauparlant, C. Makris, S. Meloche, and J. Hiscott. 1996. Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability. Mol. Cell. Biol. 16:1401-1409.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1401-1409
    • Lin, R.1    Beauparlant, P.2    Makris, C.3    Meloche, S.4    Hiscott, J.5
  • 38
    • 0028854272 scopus 로고
    • Differential transcriptional activation in vitro by NF-κB/Rel proteins
    • Lin, R., D. Gewert, and J. Hiscott. 1995. Differential transcriptional activation in vitro by NF-κB/Rel proteins. J. Biol. Chem. 270:3123-3131.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3123-3131
    • Lin, R.1    Gewert, D.2    Hiscott, J.3
  • 39
    • 0026740422 scopus 로고
    • The NF-κB p50 precursor, p105, contains an internal IκB-like inhibitor that preferentially inhibits p50
    • Liou, H.-C., G. P. Nolan, S. Ghosh, T. Fujita, nod D. Baltimore. 1992. The NF-κB p50 precursor, p105, contains an internal IκB-like inhibitor that preferentially inhibits p50. EMBO J. 11:3003-3009.
    • (1992) EMBO J. , vol.11 , pp. 3003-3009
    • Liou, H.-C.1    Nolan, G.P.2    Ghosh, S.3    Fujita, T.4    Baltimore, D.5
  • 40
    • 0030022860 scopus 로고    scopus 로고
    • Casein kinase II phosphoryiates IκBα at S-283, S-289, S-293, and T-291 and is required for its degradation
    • McElhinny, J. A., S. A. Trushin, G. D. Bren, N. Chester, and C. V. Paya. 1996. Casein kinase II phosphoryiates IκBα at S-283, S-289, S-293, and T-291 and is required for its degradation. Mol. Cell. Biol. 16:899-906.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 899-906
    • McElhinny, J.A.1    Trushin, S.A.2    Bren, G.D.3    Chester, N.4    Paya, C.V.5
  • 41
    • 0027243576 scopus 로고
    • P105 and p98 precursor proteins play an active role in NF-κB mediated signal transduction
    • Mercurio, F., J. A. DiDonato, C. Rosette, and M. Karin. 1993. p105 and p98 precursor proteins play an active role in NF-κB mediated signal transduction. Genes Dev. 7:705-718.
    • (1993) Genes Dev. , vol.7 , pp. 705-718
    • Mercurio, F.1    DiDonato, J.A.2    Rosette, C.3    Karin, M.4
  • 42
    • 0028557348 scopus 로고
    • Tumor necrosis factor α-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB
    • Miyamoto, S., M. Maki, M. J. Schmitt, M. Hatanaka, and I. M. Verma. 1994. Tumor necrosis factor α-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB. Proc. Natl. Acad. Sci. USA 91:12740-12744.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12740-12744
    • Miyamoto, S.1    Maki, M.2    Schmitt, M.J.3    Hatanaka, M.4    Verma, I.M.5
  • 43
    • 0024431684 scopus 로고
    • In vivo footprinting of a muscle specific enhancer by ligation mediated PCR
    • Mueller, P. R., and B. Wold. 1989. In vivo footprinting of a muscle specific enhancer by ligation mediated PCR. Science 244:780-786.
    • (1989) Science , vol.244 , pp. 780-786
    • Mueller, P.R.1    Wold, B.2
  • 44
    • 0032562712 scopus 로고    scopus 로고
    • Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300
    • Owen, G. I., J. K. Richer, L. Tung, G. Takimoto, and K. B. Horwitz. 1998. Progesterone regulates transcription of the p21(WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300. J. Biol. Chem. 273:10696-10701.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10696-10701
    • Owen, G.I.1    Richer, J.K.2    Tung, L.3    Takimoto, G.4    Horwitz, K.B.5
  • 45
    • 0027209915 scopus 로고
    • A cooperative interaction between NF-κB and Sp1 is required for HIV enhancer activation
    • Perkins, N. D., N. L. Edwards, C. S. Duckett, A. B. Agranoff, R. M. Schmid, and G. J. Nabel. 1993. A cooperative interaction between NF-κB and Sp1 is required for HIV enhancer activation. EMBO J. 12:3551-3558.
    • (1993) EMBO J. , vol.12 , pp. 3551-3558
    • Perkins, N.D.1    Edwards, N.L.2    Duckett, C.S.3    Agranoff, A.B.4    Schmid, R.M.5    Nabel, G.J.6
  • 46
  • 47
    • 0030297115 scopus 로고    scopus 로고
    • Human T cell leukemia virus type 1 Tax protein increases NF-κB dimer formation and antagonizes the inhibitory activity of the IκBα regulatory protein
    • Petropoulos, L., R. Lin, and J. Hiscott 1996. Human T cell leukemia virus type 1 Tax protein increases NF-κB dimer formation and antagonizes the inhibitory activity of the IκBα regulatory protein. Virology 225:52-64.
    • (1996) Virology , vol.225 , pp. 52-64
    • Petropoulos, L.1    Lin, R.2    Hiscott, J.3
  • 48
    • 0031586174 scopus 로고    scopus 로고
    • Identification and characterization of an IκB kinase
    • Régnier, C., H. Y. Song, X. Gao, D. V. Goeddel, Z. Cao, and M. Rothe. 1997. Identification and characterization of an IκB kinase. Cell 90:373-383.
    • (1997) Cell , vol.90 , pp. 373-383
    • Régnier, C.1    Song, H.Y.2    Gao, X.3    Goeddel, D.V.4    Cao, Z.5    Rothe, M.6
  • 49
    • 0028986111 scopus 로고
    • Inducible degradation of IκBα in vitro and in vivo requires the acidic C-terminal domain of the protein
    • Rodriguez, M. S., I. Michalopoulos, F. Arenzana-Seisdedos, and R. T. Hay. 1995. Inducible degradation of IκBα in vitro and in vivo requires the acidic C-terminal domain of the protein. Mol. Cell. Biol. 15:2413-2419.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2413-2419
    • Rodriguez, M.S.1    Michalopoulos, I.2    Arenzana-Seisdedos, F.3    Hay, R.T.4
  • 51
    • 0030771433 scopus 로고    scopus 로고
    • Modulation of transcription factor Sp1 by cAMP-dependent protein kinase
    • Rohlff, C., S. Ahmad, F. Borellini, J. Lei, and R. I. Glazer. 1997. Modulation of transcription factor Sp1 by cAMP-dependent protein kinase. J. Biol. Chem. 272:21137-21141.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21137-21141
    • Rohlff, C.1    Ahmad, S.2    Borellini, F.3    Lei, J.4    Glazer, R.I.5
  • 52
    • 0029128427 scopus 로고
    • Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-κB/Rel transcription factors
    • Roulston, A., R. Lin, P. Beauparlant, M. A. Wainberg, and J. Hiscott. 1995. Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-κB/Rel transcription factors. Microbiol. Rev. 59:481-505.
    • (1995) Microbiol. Rev. , vol.59 , pp. 481-505
    • Roulston, A.1    Lin, R.2    Beauparlant, P.3    Wainberg, M.A.4    Hiscott, J.5
  • 53
    • 0031596724 scopus 로고    scopus 로고
    • Nuclear localization of IκBα is mediated by the second ankyrin repeat: The IκBα ankyrin repeats define a novel class of cis-acting nuclear import sequences
    • Sachdev, S., A. Hoffmann, and M. Hannink. 1998. Nuclear localization of IκBα is mediated by the second ankyrin repeat: the IκBα ankyrin repeats define a novel class of cis-acting nuclear import sequences. Mol. Cell. Biol. 18:2524-2534.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2524-2534
    • Sachdev, S.1    Hoffmann, A.2    Hannink, M.3
  • 54
    • 0028865771 scopus 로고
    • Triggering of the human interleukin-6 gene by interferon-gamma and tumor necrosis factor-alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NF- Kappa B, and Sp1 transcription factors
    • Sanceau, J., T. Kaisho, T. Hirano, and J. Wietzerbin. 1995. Triggering of the human interleukin-6 gene by interferon-gamma and tumor necrosis factor-alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NF- kappa B, and Sp1 transcription factors. J. Biol. Chem. 17: 27920-27931.
    • (1995) J. Biol. Chem. , vol.17 , pp. 27920-27931
    • Sanceau, J.1    Kaisho, T.2    Hirano, T.3    Wietzerbin, J.4
  • 56
    • 0027168948 scopus 로고
    • The p65 subunit of NF-κB regulates IκB by two distinct mechanisms
    • Scott, M. L., T. Fujita, H.-C. Liou, G. P. Nolan, and D. Baltimore. 1993. The p65 subunit of NF-κB regulates IκB by two distinct mechanisms. Genes Dev. 7:1266-1276.
    • (1993) Genes Dev. , vol.7 , pp. 1266-1276
    • Scott, M.L.1    Fujita, T.2    Liou, H.-C.3    Nolan, G.P.4    Baltimore, D.5
  • 57
    • 0027168447 scopus 로고
    • NF-κB controls expression of inhibitor IκBα: Evidence for an inducible autoregulatory pathway
    • Sun, S.-C., P. A. Ganchi, D. W. Ballard, and W. C. Greene. 1993. NF-κB controls expression of inhibitor IκBα: evidence for an inducible autoregulatory pathway. Science 259:1912-1915.
    • (1993) Science , vol.259 , pp. 1912-1915
    • Sun, S.-C.1    Ganchi, P.A.2    Ballard, D.W.3    Greene, W.C.4
  • 58
    • 0028986194 scopus 로고
    • IκB-β regulates the persistent response in a biphasic activation of NF-κB
    • Thompson, J. E., R. J. Phillips, H. Erdjument-Bromage, P. Tempst, and S. Ghosh. 1995. IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell 80:573-582.
    • (1995) Cell , vol.80 , pp. 573-582
    • Thompson, J.E.1    Phillips, R.J.2    Erdjument-Bromage, H.3    Tempst, P.4    Ghosh, S.5
  • 59
    • 0028978032 scopus 로고
    • Phosphorylation of human IκBα on serines 32 and 36 controls IκBα proteolysis and NF-κB activation in response to diverse stimuli
    • Traenckner, E. B., H. L. Phal, T. Henkel, N. K. Schmidt, S. Wilk, and P. A. Baeuerle. 1995. Phosphorylation of human IκBα on serines 32 and 36 controls IκBα proteolysis and NF-κB activation in response to diverse stimuli. EMBO J. 14:2876-2883.
    • (1995) EMBO J. , vol.14 , pp. 2876-2883
    • Traenckner, E.B.1    Phal, H.L.2    Henkel, T.3    Schmidt, N.K.4    Wilk, S.5    Baeuerle, P.A.6
  • 60
  • 61
    • 0030899121 scopus 로고    scopus 로고
    • I kappa B epsilon, a novel member of the IκB family, controls Rela and cRel NF-κB activity
    • Whiteside, S. T., J. Epinat, N. R. Rice, and A. Israel. 1997. I kappa B epsilon, a novel member of the IκB family, controls RelA and cRel NF-κB activity. EMBO J. 16:1413-1426.
    • (1997) EMBO J. , vol.16 , pp. 1413-1426
    • Whiteside, S.T.1    Epinat, J.2    Rice, N.R.3    Israel, A.4
  • 62
    • 0030613551 scopus 로고    scopus 로고
    • The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
    • Zandi, E., D. M. Rothwarf, M. Delhase, M. Hayakawa, and M. Karin. 1997. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 91:243-252.
    • (1997) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3    Hayakawa, M.4    Karin, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.