Differential effects of intrauterine and subcutaneous administration of recombinant ovine interferon tau on the endometrium of cyclic ewes

Biology of Reproduction

Volumn 61, Issue 2, 1999, Pages 464-470

  Spencer, Thomas E ^a   Stagg, Allison G ^a   Ott, Troy L ^a,c   Johnson, Gregory A ^a   Ramsey, W Shawn ^a   Bazer, Fuller W ^a,b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF IDAHO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; MESSENGER RNA; OXYTOCIN RECEPTOR; PROSTAGLANDIN F2 ALPHA; RECOMBINANT INTERFERON; TAU INTERFERON;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORPUS LUTEUM; ENDOMETRIUM; FEMALE; GENE EXPRESSION; IN SITU HYBRIDIZATION; LAMB; NONHUMAN; PREGNANCY; PREGNANCY RATE; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; UTERUS;

ANIMALS; ANTIVIRAL AGENTS; CARRIER PROTEINS; ENDOMETRIUM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; IN SITU HYBRIDIZATION; INJECTIONS, SUBCUTANEOUS; INTERFERON TYPE I; LEUCINE ZIPPERS; PREGNANCY; PREGNANCY PROTEINS; PROTEIN BIOSYNTHESIS; PROTEINS; RECEPTORS, ESTROGEN; RECEPTORS, OXYTOCIN; RECOMBINANT PROTEINS; SHEEP; UBIQUITINS; UTERUS;

EID: 0032789833     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod61.2.464     Document Type: Article

References (41)

1. Moor RM, Rowson LEA. The corpus luteum of the sheep: functional relationship between the embryo and the corpus luteum. J Endocrinol 1966; 34:497-502.
2. Bazer FW, Spencer TE, Ott TL. Interferon tau: a novel pregnancy recognition signal. Am J Reprod Immunol 1996; 37:412-420.
3. Bazer FW, Spencer TE, Ott TL, Ing NH. Regulation of endometrial responsiveness to estrogen and progesterone by pregnancy recognition signals during the periimplantation period. In: Dey SK (ed.), Molecular and Cellular Aspects of Periimplantation Processes. New York: Springer-Verlag; 1995: 27-47.
4. Spencer TE, Ott TL, Bazer FW. Tau interferon: pregnancy recognition signal in ruminants. Proc Soc Exp Biol Med 1996; 213:215-229.
5. Roberts RM, Liu L, Alexenko A. New and atypical families of type I interferons in mammals: comparative functions, structures, and evolutionary relationships. Prog Nucleic Acid Res Mol Biol 1997; 56: 287-325.
6. Pontzer CH, Yamamoto JK, Bazer FW, Ott TL, Johnson HM. Potent anti-feline immunodeficiency virus and anti-human immunodeficiency virus effect of IFN-τ. J Immunol 1997; 158:4351-4357.
7. Ott TL, Fleming JGW, Spencer TE, Joyce MM, Chen P, Green CNK, Welsh TH Jr, Harms PH, Bazer FW. Effects of exogenous ovine interferon tau on circulating concentrations of progesterone, cortisol, LH and antiviral activity; interestrous interval; rectal temperature; and uterine response to oxytocin in cyclic ewes. Biol Reprod 1997; 57: 621-629.
8. Short EC, Geisert RD, Helmer SD, Zavy MT, Fulton RW. Expression of antiviral activity and induction of 2′,5′-oligoadenylate synthetase by conceptus secretory proteins enriched in bovine trophoblast protein-1. Biol Reprod 1991; 44:261-268.
9. Vallet JL, Barker PJ, Lamming GE, Skinner N, Huskisson NS. A low molecular weight endometrial secretory protein which is increased by ovine trophoblast protein-1 is a β2-microglobulin-like protein. J Endocrinol 1991; 130:R1-R4.
10. Spencer TE, Ott TL, Bazer FW. Expression of Interferon regulatory factors one and two in the ovine endometrium: effects of pregnancy and ovine interferon tau. Biol Reprod 1998; 58:1154-1162.
11. Austin KJ, Ward SK, Teixeira MG, Dean VC, Moore DW, Hansen TR. Ubiquitin cross-reactive protein is released by the bovine uterus in response to interferon during early pregnancy. Biol Reprod 1996; 54:600-606.
12. Austin KJ, Pru JK, Hansen TR. Complementary deoxyribonucleic acid sequence encoding bovine ubiquitin cross-reactive protein: a comparison with ubiquitin and a 15-kDa ubiquitin homolog. Endocrine 1996; 2:141-147.
13. Johnson GA, Spencer TE, Hansen TR, Austin KJ, Burghardt RC, Bazer FW. Expression of the interferon tau inducible ubiquitin cross-reactive protein in the ovine uterus. Biol Reprod 1999; 61:312-318.
14. Ott TL, Spencer TE, Lin JY, Kim H-T Gerami B, Bartol FF, Wiley AA, Bazer FW. Effects of the estrous cycle and early pregnancy on uterine expression of Mx protein in sheep (Ovis aries). Biol Reprod 1998; 59:784-794.
15. Teixieira MG, Austin KJ, Perry DJ, Dooley VD, Johnson GD, Francis BR, Hansen TR. Bovine granulocyte chemotactic protein-2 is secreted by the endometrium in response to interferon-tau. Endocrine 1997; 6: 31-37.
16. Imakawa K, Anthony RV, Kazemi M, Marotti KR, Polites HG, Roberts RM. Interferon-like sequence of ovine trophoblast protein secreted by embryonic ectoderm. Nature 1987; 330:377-379.
17. Stewart HJ, McCann SHE, Barker JJ, Lee KE, Lamming GE, Flint APF. Interferon sequence homology and receptor binding activity of ovine trophoblast antiluteolytic protein. J Endocrinol 1987; 115:R13-R15.
18. Capon DJ, Shepard HM, Goeddel DV. Two distinct families of human and bovine interferon-α genes are coordinately expressed and encode functional polypeptides. Mol Cell Biol 1985; 5:768-779.
19. Hauptman R, Swetly PA. A novel class of human type I interferons. Nucleic Acid Res 1985; 13:4739-4749.
20. Bazer FW, Thatcher WW, Hansen PJ, Mirando MA, Ott TL, Plante C. Physiological mechanisms of pregnancy recognition in ruminants. J Reprod Fertil Suppl 1991; 43:39-47.
21. 1 during the period of maternal recognition of pregnancy. J Anim Sci 1990; 68:2766-2770.
22. 1 on oestrous cycle length and pregnancy success in sheep. J Reprod Fertil 1990; 91:347-356.
23. Martinod S, Maurer RR, Siegenthaler B, Gerber C, Hansen PJ. The effects of recombinant bovine interferon-α on fertility in ewes. Theriogenology 1991; 36:231-239.
24. Davis MA, Ott TL, Mirando MA, Moser MT, Bazer FW. Effect of recombinant alpha interferons on fertility and interestrous interval in sheep. Theriogenology 1992; 38:867-875.
25. Barros CM, Betts JG, Thatcher WW, Hansen PJ. Possible mechanisms for reduction of circulation concentrations of progesterone by interferon-α in cows: effects on hyperthermia, luteal cells, metabolism of progesterone, and secretion of LH. J Endocrinol 1992; 133:175-182.
26. Ott TL, Van Heeke G, Johnson HM, Bazer FW. Cloning and expression in Saccharomyces cerevisiae of a synthetic gene for type-I trophoblast interferon ovine trophoblast protein-1. J Interferon Res 1991; 11:357-364.
27. Van Heeke G, Ott TL, Strauss A, Ammaturo D, Bazer FW. High yield cloning and expression of the ovine pregnancy recognition hormone interferon-tau by Pichia pastoris. J Interferon Cytokine Res 1996; 166:119-126.
28. Thatcher WW, Macmillan KL, Hansen PJ, Bazer FW. Embryonic losses: causes and prevention. In: Fields MJ, Sands RS (eds.), Factors Affecting Calf Crop. Boca Raton: CRC Press; 1994: 135-153.
29. Spencer TE, Ott TL, Mayes JS, Becker WC, Watson GH, Mirando MA, Bazer FW. Intrauterine injection of ovine interferon tau alters oestrogen and oxytocin receptor expression in the endometrium of cyclic ewes. J Mol Endocrinol 1995; 15:203-220.
30. Riley PR, Abayasekara DR, Stewart HJ, Flint AP. Functional characterisation of an ovine endometrial oxytocin receptor cDNA transiently expressed in Cos-7 cells. J Endocrinol 1996; 149:389-396.
31. SAS. SAS User's Guide: Statistics, Version 6. Cary, NC: Statistical Analysis System Institute, Inc.; 1990.
32. Steele RGD, Torrie JH. Principles and Procedures of Statistics. New York: McGraw-Hill; 1980.
33. Flint APF, Parkinson TJ, Stewart HJ, Vallet JL, Lamming GE. Molecular biology of trophoblast interferons and studies of their effects in vivo. J Reprod Fertil Suppl 1991; 43:13-25.
34. Stewart HJ, Flint APF, Lamming GE, McCann SHE, Parkinson TJ. Antiluteolytic effects of blastocyst-secreted interferon investigated in vitro and in vivo in the sheep. J Reprod Fertil Suppl 1989; 37:127-138.
35. Hansen TR, Kazemi M, Keisler DH, Malathy PV, Imakawa K, Roberts RM. Complex binding of the embryonic interferon, ovine trophoblast protein-1, to endometrial receptors. J Interferon Res 1989; 9:215-225.
36. Li J, Roberts RM. Interferon-tau and interferon-alpha interact with the same receptors in uterine endometrium: use of a readily iodinatable form of recombinant interferon-tau for binding studies. J Biol Chem 1994; 269:13544-13550.
37. Bagvanadoss P, Wiggins RC, Kunkel SL, Remick KG, Keyes PL. Tumor necrosis factor production and accumulation of inflammatory cells in the corpus luteum of pseudopregnancy and pregnancy in rabbits. Biol Reprod 1990; 42:367-376.
38. Murdoch WJ, Steadman LE, Beiden EL. Immunoregulation of luteolysis. Med Hypotheses 1988; 27:197-199.
39. Newton GR, Martinod S, Hansen PJ, Thatcher WW, Siegenthaler B, Gerber C, Voirol M-J. Effect of bovine interferon alpha on acute changes in body temperature and serum progesterone concentrations in heifers. J Dairy Sci 1990; 73:3439-3448.
40. Ealy AD, Alexenko AP, Keisler DH, Roberts RM. Loss of the signature six caboxyl amino acid tail from ovine interferon-tau does not affect biological activity. Biol Reprod 1998; 58:1463-1468.
41. Mapletoft RJ, Del Campo MR, Ginther OJ. Unilateral luteotropic effect of uterine venous effluent of a gravid uterine horn in sheep. Proc Soc Exp Biol Med 1975; 150:129-136.