Effect of an aqueous extract of Canavalia ensiformis (DC) seeds in normoglycaemic and alloxan-induced hyperglycaemic rats

Medical Science Research

Volumn 27, Issue 6, 1999, Pages 397-399

  Nimenibo Uadia, R ^a   Osagie, A U ^a  

^a UNIVERSITY OF BENIN   (Nigeria)

Author keywords

Alloxan diabetes mellitus; Canavalia ensiformis; Glycaemia; Phytochemical screening

Indexed keywords

ALKALOID; ANTIDIABETIC AGENT; CANAVALIA ENSIFORMIS EXTRACT; PLANT EXTRACT; SAPONIN; TANNIN DERIVATIVE; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; GLUCOSE BLOOD LEVEL; GLUCOSE URINE LEVEL; INTRAGASTRIC DRUG ADMINISTRATION; NONHUMAN; PLANT SEED; RAT; STOMACH INTUBATION;

ANIMALIA; CANAVALIA ENSIFORMIS;

EID: 0032788140     PISSN: 02698951     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. WHO. Guidelines for the assessment of herbal medicines. Programme on traditional medicines. Geneva, WHO/TRM 91.4; 1991.
2. Marfo EK, Wallace P, Timpo G, Simpson BK. Cholesterol lowering effect of jackbean (Canavalia ensiformis) seed protein. Pharmacology 1990; 21(5):753-757.
3. Carlini CR, Guimaraes JA, Isolation and characterisation of a toxic protein from Canavalia ensiformis (jackbean) seeds, distinct from concanavalinA. Toxicon 1981; 19:667-675.
4. Krupe M, Wirth W, Nies D, Ensgraber A. Studies on the 'mitogenic' effect haemaglutinating extracts of various plants on the human small lymphocytes in peripheral blood cultured in vitro. Z. Immunitatsforsch Allerg Klin Immunol 1968; 135(1): 19-2.
5. Raychaudhuri M, Singh M. A concanavalin A-like lectin in the developing seed of Canavalia ensiformis. Phytochemistry 1986; 25(4):793-797.
6. Enyikwola O, Addy EO, Adoga El. Hypolglycaemic effect of Canavalia ensiformis (Leguminosae) in albino fats. Discov Innovât 1991;3(3):61-63.
7. Wadood N, Wadood A, Shah SAW. Effect of Tinospora cordifolia on blood glucose and total lipid levels of normal and alloxan-diabetic rabbits. Planta Med 1992; 58:131-136.
8. Sofowora A. Medicinal Plants and Traditional Medicine in Africa. New York: John Wiley and Sons; 1982. pp. 142-145.
9. Harborne JB,. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. London: Chapman and Hall; 1973. pp. 279.
10. Pileggi VJ, Szustkiewicz CP. In: Henry RJ, Canon DC, Winkelman JW (editors): Clinical Chemistry, Principles and Techniques, 2nd ed. New York: Harper and Row; 1974. pp. 1265-1326.
11. Peter H, Bennett MB. In: Ellenberg M, Rifkin H (editors): Diabetes Mellitus - Theory and Practice. New York: Medical Examination Publishing Co. Inc.; 1983. pp. 409-414.
12. Oliver Bever B. Oral hypoglycaemic plants in West Africa. J Ethnopharmacol 1980; 2:119-127.
13. Thompson LU. Potential health benefits and problems associated with antinutrients in foods. Food Res Int 1993; 26:131-149.
14. Chakravarthy BK, Gupta S, Gode KD. Functional beta cell regeneration in the islets of pancreas in alloxan-induced diabetic rats (-)-epicatechin. Life Sci 1982; 31:2693-2697.
15. Goth A. Medical Pharmacology, 10th edn. St. Louis: The C.V. Mosby Company; 1991. pp. 534.
16. Goodman G, Oilman A. The Pharmacological Basis of Therapeutics 7th edn. New York: MacMillan; 1985. pp. 1490-1516.