Improved postprandial glycemic control during treatment with Humalog Mix25, a novel protamine-based insulin lispro formulation

Diabetes Care

Volumn 22, Issue 8, 1999, Pages 1258-1261

  Roach, Paris ^a   Yue, Lilly ^a   Arora, Vipin ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HUMALOG MIX 25; HUMAN INSULIN; INSULIN LISPRO; PROTAMINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD GLUCOSE MONITORING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETES CONTROL; DRUG FORMULATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MEAL; NON INSULIN DEPENDENT DIABETES MELLITUS; RANDOMIZED CONTROLLED TRIAL;

EID: 0032787906     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.22.8.1258     Document Type: Article

References (18)

1. Edelman SV Henry RR: Insulin therapy for normalizing glycosylated hemoglobin in type II diabetes. Diabetes Rev 3:308-334, 1995
2. Bell DSH, Clements RS, Perentesis G, Roddam R, Wagenknecht L: Dosage accuracy of self-mixed vs. premixed insulin. Arch Intern Med 151:2265-2269, 1991
3. Coscelli C, Calabrese G, Fedele D, Pisu E, Calderini C, Bistoni S, Lapolla A, Mauri MG, Rossi A, Zapella A: Use of premixed insulin among the elderly: reduction of errors in patient preparation of mixtures. Diabetes Care 15:1628-1630, 1992
4. Howey DC, Bowsher RR, Brunelle RL, Woodworth JR: [Lys(B28) Pro(B29)]-human insulin: a rapidly absorbed analogue of human insulin. Diabetes 43:396-402, 1994
5. Anderson JH Jr, Brunelle RL, Koivisio VA, Pfutzner A, Trautmann ME, Vignati L, DiMarchi R, Multicenter Insulin Lispro Study Group: Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment. Diabetes 46:265-270, 1997
6. Anderson JH Jr, Brunelle RL, Keohane P, Koivisto VA, Trautmann ME, Vignati L, DiMarchi R: Mealtime treatment with insulin analog improves postprandial hyperglycemia and hypoglycemia in patients with non-insulin-dependent diabetes mellitus. Arch Intern Med 157: 1249-1255, 1997
7. Dimitriadis GD, Gerich JE: Importance of timing of preprandial subcutaneous insulin administration in the management of diabetes mellitus. Diabetes Care 6:374-377, 1983
8. Radziuk JR, Bradley B, Welsh L, DeFelippis MR, Roach P: Neutral protamine lispro: activity profile of s.c. administration with and without admixture of soluble lispro (Abstract). Diabetologia 39 (Suppl. 1):A224, 1996
9. Janssen MMJ, Casteleijn S, Deville W, Popp-Snijders C, Roach P, Heine RJ: Nighttime insulin kinetics and glycemic control in type 1 diabetes patients following administration of an intermediate-acting lispro preparation. Diabetes Care 20:1870-1873, 1997
10. Bennett PH: Classification and diagnosis of diabetes mellitus. In Textbook of Diabetes. Vol. 1. Pickup JC, Williams G, Eds. London, Blackwell Scientific Publications, 1991, p. 37-46
11. Koch GG: The use of non-parametric methods in statistical analysis of the two period change-over design. Biometrics 28:577-584, 1972
12. Taulbee JD: A note on the use of nonparametric methods in the statistical analysis of the two-period changeover design. Biometrics 38:1053-1055, 1982
13. Grizzle JE: The two-period change-over design and its use in clinical trials. Biometrics 21:467-480, 1965
14. Heise T, Weyer C, Serwas A, Heinrichs S, OsingaJ, Roach P, WoodworthJ, Gudat U, Heinemann L: Time-action profiles of novel pre-mixed preparations of insulin lispro and NPL insulin. Diabetes Care 21:800-803, 1998
15. Vignati L, Anderson JHJr, Iversen PH: Efficacy of insulin lispro in combination with NPH human insulin twice per day in patients with insulin-dependent or non-insulin dependent diabetes mellitus. Clin Therapeut 19:1408-1421, 1997
16. Bell D, Bode B, Clements RS, Herron J, Hollander PA, Kumar D, Perentesis GP, Sosenko J: Premixed vs. self-mixed insulin in the treatment of type II diabetes mellitus: a randomized trial. Today's Therapeutic Trends 9:63-73, 1991
17. Aronoff S, Goldberg R, Kumar D, Lichtenstein E, Schwartz S, Sosenko J: Use of a premixed insulin regimen (Novolin 30/70) to replace self-mixed insulin regimens. Clin Therapeut 16:41-49, 1994
18. Bell DSH, Cutter GR, Lauritano AA: Efficacy of a premixed semisynthetic human insulin regimen. Clin Therapeut 11:795-801, 1989