Nighttime insulin kinetics and glycemic control in type 1 diabetes patients following administration of an intermediate-acting lispro preparation

Diabetes Care

Volumn 20, Issue 12, 1997, Pages 1870-1873

  Janssen, Maureen M J ^a   Casteleijn, Sandrina ^a   Devillé, Walter ^b   Popp Snijders, Corrie ^a   Roach, Paris ^c   Heine, Robert J ^a,d  

^a University Hospital   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c ELI LILLY AND COMPANY   (United States)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN LISPRO; ISOPHANE INSULIN;

ADULT; AREA UNDER THE CURVE; ARTICLE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIABETES CONTROL; DOUBLE BLIND PROCEDURE; FEMALE; GLUCOSE BLOOD LEVEL; HORMONE SUBSTITUTION; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN METABOLISM; MALE; RANDOMIZED CONTROLLED TRIAL; RECOMBINANT DNA TECHNOLOGY; TRANSPORT KINETICS;

EID: 0030856270     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.20.12.1870     Document Type: Article

References (15)

1. Galloway JA, Chance RE: Improving insulin therapy: achievements and challenges. Horm Metab Res 26:591-598, 1994
2. DiMarchi RD, Mayer JP, Fan L, Brems DN, Frank BH, Green LK, Hoffmann JA, Howey DC, Long HB, Shaw WN, Shields JE, Slieker LJ, Su KSE, Sundell KL, Chance RE: Synthesis of a fast-acting insulin based on structural homology with insulin-like growth factor I. In Peptides: Chemistry and Biology, Proceedings of the Twelfth American Peptide Symposium. Smith JA, Rivier JE, Eds. Leiden, The Netherlands, ESCOM, 1992, p. 26-28
3. Ciszak E, Beals JM, Frank BH, Baker JC, Carter ND, Smith GD: Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric Lys(B28),Pro(B29) human insulin. Structure 3:615-622, 1995
4. Pampanelli S, Torlone E, Lalli C, Del Sindaco P, Ciofetta M, Lepore M, Bartocci L, Brunetti P, Bolli GB: Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic β-cell function. Diabetes Care 18:1452-1459, 1995
5. Howey DC, Bowsher RR, Brunelle RL, Woodworth JR: [Lys(B28),Pro(B29)] human insulin: a rapidly absorbed analogue of human insulin. Diabetes 43:396-402, 1994
6. Anderson JH Jr, Brunelle RL, Vignati L: Insulin lispro improved postprandial glucose control and reduced hypoglycemia rate in type 1 diabetes (Abstract). Diabetologia 38 (Suppl. 1):A3, 1995
7. Küstner E, Forst T, Pfützner A, Trautmann M, Beyer J: Insulin lispro improves postprandial blood glucose control without increase in the frequency of hypoglycemia (Abstract). Diabetologa 38 (Suppl. 1):A190, 1995
8. Heinemann L, Heise T, Wahl LC, Trautmann ME, Ampudia J, Starke AAR, Berger M: Prandial glycaemia after a carbohydrate-rich meal in type 1 diabetic patients: using the rapid acting insulin analogue [Lys(B28),Pro(B29)] human insulin. Diabet Med 13:625-629, 1996
9. Torlone E, Pampanelli S, Lalli C, Del Sindaco P, Di Vincenzo A, Rambotti AM, Modarelli F, Epifano L, Kassi G, Perriello G, Brunetti P, Bolli G: Effects of the short-acting insulin analog [Lys(B28),Pro(B29)] on postprandial blood glucose control in IDDM. Diabetes Care 19:945-952, 1996
10. Trautmann ME: Effect of the insulin analogue [Lys(B28),Pro(B29)] on blood glucose control. Horm Metab Res 26:588-590, 1994
11. Radziuk JR, Bradley B, Welsh L, De Fellippis MR, Roach P: Neutral protamine lispro: activity profile of s.c. administration with and without admixture of soluble lispro (Abstract). Diabetologia 39 (Suppl. 1):A224, 1996
12. Holloway DL, Santa PF, Compton JA, Bowsher RR: Humalog, a rapidly absorbed analog of human insulin, determined with Coat-a-Count insulin radioimmunoassay. Clin Chem 41:1777-1778, 1995
13. Arnqvist H, Olsson PO, Von Schenck H: Determination of free and total insulin after precipitation with polyethylene glycol: analytical characteristics and effects of sample handling and storage. Clin Chem 33:93-96, 1987
14. Altman DG: Practical Statistics for Medical Research. London, Chapman and Hall, 1991
15. Fleiss JL: The Design and Analysis of Clinical Experiments. New York, Wiley, 1986