Factors associated with regional nodal failure in patients with early stage breast cancer with 0-3 positive axillary nodes following tangential irradiation alone

International Journal of Radiation Oncology Biology Physics

Volumn 45, Issue 5, 1999, Pages 1157-1166

  Galper, Sharon ^a,d   Recht, Abram ^c,d   Silver, Barbara ^c   Manola, Judy ^b   Gelman, Rebecca ^b   Schnitt, Stuart J ^c   Connolly, James L ^c   Harris, Jay R ^a,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Axillary dissection; Breast cancer; Regional nodes

Indexed keywords

ADULT; AGED; ARTICLE; AXILLARY LYMPH NODE; BREAST CANCER; BREAST METASTASIS; CANCER CONTROL; CANCER RECURRENCE; CANCER RISK; CANCER STAGING; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; TREATMENT FAILURE; TUMOR VOLUME;

ADULT; AGED; AXILLA; BREAST NEOPLASMS; COMBINED MODALITY THERAPY; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; TREATMENT FAILURE;

EID: 0032785070     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(99)00334-X     Document Type: Article

References (21)

1. Overgaard M., Hansen P.S., Overgaard J., et al. Post-operative radiotherapy in high-risk pre-menopausal women with breast cancer who receive adjuvant chemotherapy. N Engl J Med. 337:1997;949-955.
2. Ragaz J., Jackson S.M., Le N., et al. Adjuvant radiotherapy and chemotherapy in node-positive pre-menopausal women with breast cancer. N Engl J Med. 337:1997;956-962.
3. Overgaard M., Jensen M.B., Overgaard J., et al. Post-operative radiotherapy in high-risk postmenopausal breast cancer patients given adjuvant tamoxifen Danish Breast Cancer Cooperative Group DBCG 82c randomised trial . Lancet. 353:1999;1641-1648.
4. Lingos T., Recht A., Vicini F., et al. Radiation pneumonitis in breast cancer patients treated with conservative surgery and radiation therapy. Int J Radiat Oncol Biol Phys. 21:1991;355-369.
5. Pierce S., Recht A., Lingos T., et al. Long-term radiation complications following conservative surgery (CS) and radiation therapy (RT) in patients with early stage breast cancer. Int J Radiat Oncol Biol Phys. 23:1992;915-923.
6. Larson D., Weinstein M., Goldberg I., et al. Edema of the arm as a function of the extent of axillary surgery in patients with stage I and II breast cancer treated with primary radiotherapy. Int J Radiat Oncol Biol Phys. 12:1986;1575-1582.
7. Cuzick J., Stewart J., Rutqvist L., et al. Cause-specific mortality in long-term survivors of breast cancer who participated in trials of radiotherapy. J Clin Oncol. 12:1994;447-453.
8. Rutqvist L.E., Lax A., Fornandes T., et al. Cardiovascular mortality in a randomized trial of adjuvant radiation versus surgery alone in primary breast cancer. Int J Radiat Oncol Biol Phys. 22:1992;887-896.
9. Harris JR, Morrow M. Local management of invasive breast cancer. In: Harris JR, Lippman M, Morrow M, Hellman S. Diseases of the breast. Philadelphia: Lippincott; 1996. p. 649-668.
10. Neugut A., Robinson E., Lee W., et al. Lung cancer after radiation therapy for breast cancer. Cancer. 71:1993;3054-3057.
11. Neugut A., Murray T., Santos J., et al. Increased risk of lung cancer after breast cancer radiation therapy in cigarette smokers. Cancer. 73:1994;1615-1620.
12. Fisher B., Redmond C., Fisher E.R., et al. Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation. N Eng J Med. 312:1985;674-681.
13. Fowble B., Solin L.J., Schultz D.J., et al. Frequency, sites of relapse, and outcome of regional node failures following conservative surgery and radiation for early breast cancer. Int J Radiat Oncol Biol Phys. 17:1989;703-710.
14. Kuske R.R., Hayden D., Bischoff R., et al. The impact of extracapsular axillary nodal extension (ECE) with and without irradiation on patterns of failure and survival from breast cancer (Abstr). Int J Radiat Oncol Biol Phys. 36:(Suppl. 1):1996;277.
15. Halverson K.J., Taylor M.E., Perez C.A., et al. Regional nodal management patterns of failure following conservative surgery and radiation therapy for stage I and II breast cancer. Int J Radiat Oncol Biol Phys. 26:1993;593-599.
16. Chadha M., Chabon A.D., Friedmann P., et al. Predictors of axillary lymph node metastases in patients with T1 breast cancer A multivariate analysis . Cancer. 73:1994;350-353.
17. Wong J.S., O'Neill A., Recht A., et al. The relationship between lymphatic vessel invasion, tumor size and pathologic nodal status Can we predict who can avoid a third field in the absence of axillary dissection? Int J Radiat Oncol Biol Phys (Abstr). 42:(Suppl. 1):1998;2048.
18. Schnitt S.J., Connolly J.C., Khettry U., et al. Pathologic findings on reexcision of the primary site in breast cancer patients considered for treatment by primary radiation therapy. Cancer. 59:1987;675-681.
19. Gage I., Schnitt S.J., Nixon A.J., et al. Pathologic margin involvement and the risk of recurrence in patients treated with breast conserving therapy. Cancer. 78:1996;1921-1928.
20. Parks C., Mitsumori M., Recht A., et al. The relationship between pathologic margin status and outcome after breast-conserving therapy. Int J Radiat Oncol Biol Phys (Abstr). 42:(Suppl. 1):1998;125.
21. Halverson K.J., Taylor M.E., Perez C.A., et al. Management of the axilla in patients with breast cancer one centimeter or smaller. Am J Clin Oncol. 17:1994;461-466.