Comparison of tacalcitol ointment with short-contact dithranol therapy in the treatment of psoriasis vulgaris: A randomized multicentre, open prospective study on efficacy and safety

Journal of Dermatological Treatment

Volumn 10, Issue 2, 1999, Pages 93-99

  Farkas, Beatrix ^c   Dobozy, A ^a   Horvath A ^b   Hunyadi, J ^d   Schneider, I ^d  

^a UNIVERSITY OF SZEGED   (Hungary)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^c UNIVERSITY OF PÉCS   (Hungary)

^d NONE

Author keywords

Dithranol; Psoriasis; Tacalcitol; Vitamin D3

Indexed keywords

ANTIPSORIASIS AGENT; DITHRANOL; TACALCITOL;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ERYSIPELAS; ERYTHEMA; FEMALE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MYALGIA; PRIORITY JOURNAL; PSORIASIS VULGARIS; SKIN IRRITATION; TOPICAL DRUG ADMINISTRATION; TREATMENT OUTCOME; VIRUS INFECTION;

EID: 0032784451     PISSN: 09546634     EISSN: None     Source Type: Journal    
DOI: 10.3109/09546639909056009     Document Type: Article

References (38)

1. Galewsky E, Über Cignolin ein Ersatzpräparat des Chrysarobins. Dermatol Wochnschr (1916) 62: 113-15.
2. Ashton RE, Anthralin: historical and current perspectives. J Am Acad Dermatol (1983) 9: 173.
3. Ingram JT, The approach to psoriasis. BMJ (1953) 2: 591-4.
4. Kerkhof PCM van de, Dithranol treatment for psoriasis: after 75 years, still going strong! Eur J Dermatol (1991) 1: 79-88.
5. Young E, Treatment of psoriasis with dithranol cream compared with dithranol paste. Dermatologica (1986) 173: 285-7.
6. Ryatt KS, Statham BN, Rowell NR, Short-contact modification of the Ingram regime. Br J Dermatol (1984) 111: 455-9.
7. Grattan CEH, Hallam F, Whitefield M, A new aqueous dithranol gel for psoriasis: comparison with placebo and calcipotriol ointment. J Dermatol Treat (1997) 8: 11-15.
8. Kerkhof PCM van de, Snater E, Verbeek-Gijsbers W et al, Intensified outpatient short-contact treatment with dithranol. J Dermatol Treat (1997) 8: 64-7.
9. Schaefer H, Farber EM, Goldberg L, Schalla W, Limited application period for dithranol in psoriasis. Br J Dermatol (1980) 102: 571-3.
10. Runne U, Kunze J, Short-duration ('minutes') therapy with dithranol for psoriasis: a new outpatient regimen. Br J Dermatol (1982) 106: 135-40.
11. Fuchs J, Zimmer G, Wöbling RH, Milbrandt R, On the interaction between anthralin and mitochondria: a revision. Arch Dermatol Res (1986) 279: 59-65.
12. Reed Cl, Struck HC, Steck IE, Other therapeutic applications of vitamin D. In: Reed Cl, Struck HC, Steck IE (eds) Vitamin D chemistry, physiology, pharmacology, pathology, experimental and clinical investigations. The University of Chicago: Chicago, 1939, pp 312-13.
13. 3. Med J Osaka Vniv (1985) 35: 51-4.
14. 3 analogue, 1,24-dihydroxy-cholecalciferol. Br J Dermatol (1986) 115: 431-3.
15. 3 analogue (MC 903) in a double-blind study. Br J Dermatol (1988) 119: 223-30.
16. Kerkhof PCM van de, Werfel T, Haustein UF et al, Tacalcitol ointment in the treatment of psoriasis vulgaris: a multicentre, placebo-controlled, double-blind study on efficacy and safety. Br J Dermatol (1996) 135: 758-65.
17. Kimura H, Nishiyama S, Nakamizo Y, Study on the efficacy of TV-02 ointment on psoriasis. West Jpn Dermatol (1989) 51: 970-9.
18. 3 for the treatment of psoriasis. Review of the literature. Eur J Dermatol (1993) 3: 255-61.
19. Scarpa C, Tacalcitol ointment is an efficacious and well tolerated treatment for psoriasis. J Eur Acad Dermatol Venereol (1996) 6: 142-6.
20. Kimura H, Nishiyama S, Nakamizo Y et al, Investigation of the usefulness of TV-02 ointment for patients with psoriasis - right and left comparison test with betamethasone valerate ointment. West Jpn Dermatol (1989) 51: 963-9.
21. Fredriksson T, Pettersson U, Severe psoriasis - oral therapy with a new retinoid. Dermatologica (1978) 157: 238-44.
22. Wei LJ, Lachin JM, Two-sample asymptotically distribution-free tests for incomplete multivariate observations. J Am Stat Assoc (1984) 79: 653-61.
23. Lachin JM, Some large-sample distribution-free estimators and tests for multivariate partially incomplete data from two populations. Stat Med (1992) 11: 1151-70.
24. Colditz GA, Miller JN, Mosteller F, Measuring gain in the evaluation of medical technology: the probability of a better outcome. Int J Technol Assess Health Care (1988) 4: 637-42.
25. Hauck WW, Anderson S, A proposal for interpreting and reporting negative studies. Stat Med (1986) 5: 203-9.
26. Paramsothy Y, Lawrence CM, Time course and intensity of anthralin inflammation on involved and uninvolved psoriatic skin. Br J Dermatol (1987) 116: 517-19.
27. Lawrence CM, Topical dithranol (anthralin). J Dermatol Treat (1997) 8: 31-2.
28. Berth-Jones J, Chu AC, Dodd WAH et al, A multicentre, parallel-group comparison of calcipotriol ointment and short-contact dithranol therapy in chronic plaque psoriasis. Br J Dermatol (1992) 127: 266-71.
29. Berth-Jones J, Topical vitamin D analogues. J Dermatol Treat (1997) 8: 32-5.
30. Kerkhof PCM van de, Vleuten CJM van de, Gerritsen MJP et al, Long-term efficacy and safety of once daily treatment of chronic plaque psoriasis with tacalcitol ointment. Eur J Dermatol (1997) 7: 421-5.
31. Farkas B, Comparison of tacalcitol with dithranol. Dermatol Newsletter (1996) 4: 1.
32. Eto M, Nishiyama S, Nakamizo Y et al, Study on the efficacy of TV-02 ointment for psoriasis - results of a double-blind study of left and right sides with a placebo (ointment base) as a control. Nishinihon J Dermatol (1991) 53: 1252-61.
33. Baadsgaard O, Traulsen J, Roed-Petersen J, Jakobsen HB, Optimal concentration of tacalcitol in once-daily treatment of psoriasis. J Dermatol Treat (1995) 6: 145-50.
34. Bettinger J, Gloor M, Fluhr J, Gehring W, Therapeutischer Nutzen von Tacalcitol bei der Psoriasis vulgaris unter besonderer Berücksichtigung der okklusiven Applikation. Z Hautkr (1996) 71: 28-32.
35. Greaves MW, Topical corticosteroids. J Dermatol Treat (1997) 8: 35-6.
36. Wilkinson JM, Hypersensitivity to topical corticosteroids. Clin Exp Dermatol (1994) 19: 1-11.
37. Farkas B, Bonnekoh B, Mahrle G, Repeated treatment with dithranol induces a tolerance reaction in keratinocytes in vitro. Arch Dermatol Res (1991) 283: 337-41.
38. MacKie RM, Topical coal tar. J Dermatol Treat (1997) 8: 30-1.