Bone material elasticity in a murine model of osteogenesis imperfecta

Connective Tissue Research

Volumn 40, Issue 3, 1999, Pages 189-198

  Mehta, Shreefal S ^a   Antich, Peter P ^a   Landis, William J ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b Northeastern Ohio Medical University   (United States)

Author keywords

Animal model; Bone matrix; Elasticity; Osteogenesis imperfecta; Ultrasound velocity

Indexed keywords

ANIMALIA; MURINAE;

EID: 0032784138     PISSN: 03008207     EISSN: None     Source Type: Journal    
DOI: 10.3109/03008209909005282     Document Type: Article

References (63)

1. Byers, P.H. and Steiner, R.D. (1992). Osteogenesis imperfecta. Ann. Rev. Med., 43, 269-282.
2. Prockop, D.J., Kuivaniemi, H. and Tromp, G. (1994). Molecular basis of osteogenesis imperfecta and related disorders of bone. Clin. Plastic Surg., 21, 407-413.
3. Cole, W.G. and Dalgleish, R. (1995). Perinatal lethal osteogenesis imperfecta. J. Medical Genetics, 32, 284-289.
4. Mundlos, S., Chan, D., Weng, Y.M., Sillence, D.O., Cole, W.G. and Bateman, J.F. (1996). Multiexon deletions in the type I collagen COL1A2 gene in osteogenesis imperfecta type IB. Molecules containing the shortened alpha 2(I) chains show differential incorporation into the bone and skin extracellular matrix. J. Biol. Chem., 271, 21068-21074.
5. Ankrom, M.A., Shapiro, J.R. and Fedarko, N.S. (1996). A deficit in the feedback between the extracellular matrix and osteogenesis imperfecta cells. J. Bone Miner. Res., 11, S250.
6. Cohen, I.R., Gajko, A. and Marini, J.C. (1996). Expression and regulation of type I collagen and other matrix components in osteogenesis imperfecta osteoblasts. J. Bone Miner. Res., 11, S251.
7. Vetter, U., Weis, M.A., Morike, M., Eanes, E.D. and Eyre, D.R. (1993). Collagen crosslinks and mineral crystallinity in bone of patients with osteogenesis imperfecta. J. Bone Miner. Res., 8, 133-137.
8. Cassella, J.P., Pereira, R., Khillan, J.S., Prockop, D.J., Garrington, N. and Ali, S.Y. (1994). An ultrastructural, microanalytical, and spectroscopic study of bone from a transgenic mouse with a COL1.A1 pro-alpha-1 mutation. Bone, 15, 611-619.
9. Stoss, H. and Freisinger, P. (1993). Collagen fibrils of osteoid in osteogenesis imperfecta: morphometrical analysis of the fibril diameter. Am. J. Med. Genet., 45, 257.
10. Landis, W.J. (1995). The strength of a calcified tissue depends in part on the molecular structure and organization of its constituent mineral crystals in their organic matrix. Bone, 16, 533-544.
11. Fratzl, P., Paris, O., Klaushofer, K. and Landis, W.J. (1996). Bone mineralization in an osteogenesis imperfecta mouse model studied by small-angle X-ray scattering. J. Clin. Invest., 97, 396-402.
12. Vetter, U., Eanes, E.D., Kopp, J.B., Termine, J.D. and Robey, P.G. (1991). Changes in apatite crystal size in bones of patients with osteogenesis imperfecta. Calcif. Tissue Int., 49, 248-250.
13. Traub, W., Arad, T., Vetter, U. and Weiner, S. (1994). Ultrastructural studies of bones from patients with osteogenesis imperfecta. Matrix Biology, 14, 337-345.
14. Chipman, S.D., Sweet, H.O., McBride, Jr., D.J., Davisson, M.T., Marks, Jr., S.C., Shuldiner, A.R., Wenstrup, R.J., Rowe, D.W. and Shapiro, J.R. (1993). Defective pro alpha 2(I) collagen synthesis in a recessive mutation in mice: a model of human osteogenesis imperfecta. Proc. Natl. Acad. Sci. USA, 90, 1701-1705.
15. Pereira, R., Khilian, J., Helminen, H., Hume, E. and Prockop, D. (1993). Transgenic mice expressing a partially deleted gene for Type I procollagen (COL1A1). J. Clin. Invest., 91, 709-716.
16. Jepsen, K.J., Goldstein, S.A., Kuhn, J.L., Schaffler, M.B. and Bonadio, J. (1996). Type-I collagen mutation compromises the post-yield behavior of Mov13 long bone. J. Orthop. Res., 14, 493-499.
17. Bonadio, J., Jepsen, K.J., Mansoura, M.K., Jaenisch, R., Kuhn, J.L. and Goldstein, S.A. (1993). A murine skeletal adaptation that significantly increases cortical bone mechanical properties. Implications for human skeletal fragility. J. Clin. Invest., 92, 1697-1705.
18. Pereira, R.F., Hume, E.L., Halford, K.W. and Prockop, D.J. (1995). Bone fragility in transgenic mice expressing a mutated gene for type 1 procollagen (COL1A1) parallels the age-dependent phenotype of human osteogenesis imperfecta. J. Bone Miner. Res., 10, 1837-1843.
19. Misof, K., Landis, W.J., Klaushofer, K. and Fratzl, P. (1997). Collagen from the osteogenesis imperfecta mouse model (oim) shows reduced resistance against tensile stress. J. Clin. Invest., 100, 40-45.
20. Lees, S. (1989). Sonic velocity and the ultrastructure of mineralized tissues. In Calcified Tissue, D.W. Hukins (ed.), pp. 121-152, London: MacMillan.
21. Lipson, S. and Katz, J. (1984). The relationship between elastic properties and microstructure of cortical bone. J. Biomech., 17, 231-240.
22. Martin, R. (1991). Determinants of the mechanical properties of bones. J. Biomech., 24, 79-88.
23. Mehta, S., Öz, O. and Antich, P. (1998). Bone elasticity and ultrasound velocity are affected by subtle changes in organic matrix. J. Bone Miner. Res., 13, 114-119.
24. Katz, J. (1981). Composite material models for cortical bone. In Mechanical Properties of Bone, S. Cowin (ed.), Vol. AMD-45, pp. 171-184. New York: American Society of Mechanical Engineers.
25. Love, A. (1927). A Treatise on the Mathematical Theory of Elasticity, Cambridge: University Press.
26. Dunn, M., McBride, D. and Shapiro, J. (1995). Absence of the collagen α2(I) chain diminishes the mechanical properties of bone. Trans. Orthop. Res. Soc., 20, 153.
27. Camacho, N.P., Landis, W.J. and Boskey, A.L. (1996). Mineral changes in a mouse model of osteogenesis imperfecta detected by Fourier transform infrared microscopy. Connect. Tissue Res., 35, 259-265.
28. Antich, P., Anderson, J., Ashman, R., Dowdey, J., Gonzales, J., Murry, R., Zerwekh, J. and Pak, C. (1991). Measurement of mechanical properties of bone material in vitro by ultrasound reflection: Methodology and comparison with ultrasound transmission. J. Bone Miner. Res., 6, 417-426.
29. Antich, P. and Mehta, S. (1997). UCR (ultrasound critical-angle reflectometry): A new modality for functional elastometric imaging. Physics Med. Biol., 42, 1763-1777.
30. Mehta, S. (1995). Analysis of mechanical properties of bone material using nondestructive ultrasound reflectometry. Ph.D. thesis. University of Texas Southwestern Medical Center.
31. Antich, P. (1993). Ultrasound study of bone in vitro. Calcif. Tissue Int., 53, S157-S161.
32. Pak, C., Sakhaee, K., Antich, P., Zerwekh, J., Peterson, R., Piziak, V., Gonzales, J., Hatab, M. and Poindexter, J. (1993). Update on the treatment of osteoporosis with intermittent slow release sodium fluoride and continuous calcium chloride. Proc. Fourth International Symposium on Osteoporosis, 122-124. Rødovre, Denmark: Osteopress.
33. Mehta, S.S. and Antich, P.P. (1998). Discrete demineralization maintains stress-strain distribution in bone material. Annals Biomed. Eng., 26, S75.
34. Ashman, R., Antich, P., Gonzales, J., Anderson, J. and Rho, J. (1994). A comparison of reflection and transmission ultrasonic techniques for measurement of cancellous bone elasticity. J. Biomech., 27, 1195-1199.
35. Auld, B. (1973). Acoustic Fields and Waves in Solids, New York: John Wiley and Sons.
36. Carando, S., Portigliatti, B., Ascenzi, A. and Boyde, A. (1989). Orientation of collagen in human tibial and fibular shafts and possible correlation with mechanical properties. Bone, 10, 139-142.
37. Evans, F. and Vincentelli, R. (1969). Relation of collagen fiber orientation to some mechanical properties of human cortical bone. J. Biomech., 2, 63-71.
38. Boyde, A. and Riggs, C. (1990). The quantitative study of the orientation of collagen in compact bone slices. Bone, 11, 35-39.
39. Martin, R. and Boardman, D. (1993). The effects of collagen fibre orientation, porosity, density, and mineralization on bovine cortical bone bending properties. J. Biomech., 26, 1047-1054.
40. Volpi, M. and Katz, E. (1991). On the adaptive structures of the collagen fibres of bone and cartilage. J. Biomech., 24, 67-77.
41. Pidaparti, R. and Burr, D. (1992). Collagen fibre orientation and geometry effects on the mechanical properties of secondary osteons. J. Biomech., 25, 869-880.
42. Lees, S. and Davidson, C. (1977). The role of collagen in the elastic properties of calcified tissues. J. Biomech., 10, 473-486.
43. Katz, J. (1980). Anisotropy of Young's modulus of bone. Nature, 283, 106-107.
44. Katz, J., Yoon, H., Lipson, S., Maharidge, R., Meunier, A. and Christel, P. (1984). The effects of remodeling on the elastic properties of bone. Calcif. Tissue Int., 36, S31-S36.
45. Yoon, H. S. and Katz, J.L. (1976). Ultrasonic wave propagation in human cortical bone-II. Measurements of elastic properties and hardness. J. Biomech., 9, 459-464.
46. Yoon, H.S. and Katz, J.L. (1976). Ultrasonic wave propagation in human cortical bone-I. Theoretical considerations for hexagonal symmetry. J. Biomech., 9, 407-412.
47. Ashman, R.B., Cowin, S.C., Van Buskirk, W.C. and Rice, J.C. (1984). A continuous wave technique for the measurement of the elastic properties of cortical bone. J. Biomech., 17, 349-361.
48. Van Buskirk, W.C., Cowin, S.C. and Ward, R.N. (1981). Ultrasonic measurement of orthotropic elastic constants of bovine femoral bone. J. Biomech. Engin., 103, 67-72.
49. Frost, H.M. (1987). Osteogenesis imperfecta. The set point proposal (a possible causative mechanism). Clin. Orthop. Rel. Res., 216, 280-297.
50. Alman, B. and Frasca, P. (1987). Fracture failure mechanisms in patients with osteogenesis imperfecta. J. Orthop. Res., 5, 139-143.
51. Shapiro, P., Tseng, K., Smith, E. and Goldstein, S. (1995). Morphologic comparison between normal and osteogenesis imperfecta tibial cortical bone with consequential biomechanical properties. J. Bone Miner. Res., 10, S502.
52. Han, S., Medige, J. and Ziv, I. (1996). The effect of ultrasonically determined anisotropy on longitudinal fracture of cortical bone. Proceedings of the Institution of Mechanical Engineers - Part H. J. Engin. Med., 210, 127-129.
53. Sasaki, N., Matsushima, N., Ikawa, T., Yamamura, H. and Fukuda, A. (1989). Orientation of bone mineral and its role in the anisotropic mechanical properties of bone - transverse anisotropy. J. Biomech., 22, 157-164.
54. Hasegawa, K., Turner, C.H. and Burr, D.B. (1994). Contribution of collagen and mineral to the elastic anisotropy of bone. Calcif. Tissue Int., 55, 381-386.
55. Takano, Y., Turner, C.H. and Burr, D.B. (1996). Mineral anisotropy in mineralized tissues is similar among species and mineral growth occurs independently of collagen orientation in rats: results from acoustic velocity measurements. J. Bone Miner. Res., 11, 1292-1301.
56. Bundy, K. (1985). Determination of mineral-matrix bonding effectiveness in bone - theoretical considerations. Ann. Biomed. Engin., 13, 119-135.
57. Lees, S. and Page, E. (1992). A study of some properties of mineralized turkey leg tendon. Connect. Tissue Res., 28, 263-287.
58. Currey, J. (1969). The relationship between the stiffness and the mineral content of bone. J. Biomech., 2, 477-480.
59. Currey, J. (1969), The mechanical consequences of variation in the mineral content in bone. J. Biomech., 2, 1-11.
60. Burstein, A., Zika, J., Heiple, K. and Klein, L. (1975). Contribution of collagen and mineral to the elastic-plastic properties of bone. J. Bone Joint Surg., 57-A, 956-961.
61. Ricos, V., Pedersen, D.R., Brown, T.D., Ashman, R.B., Rubin, C.T. and Brand, R.A. (1996). Effects of anisotropy and material axis registration on computed stress and strain distributions in the turkey ulna. J. Biomech., 29, 261-267.
62. Antich, P., Pak, C., Gonzales, J., Anderson, J., Sakhaee, K. and Rubin, C. (1993). Measurement of intrinsic bone quality in vivo by reflection ultrasound: Correction of impaired quality with slow-release sodium fluoride and calcium citrate. J. Bone Miner. Res., 8, 301-311.
63. Mehta, S. and Antich, P. (1997). Measurement of shearwave velocity by ultrasound critical-angle reflectometry (UCR). Ultrasound in Med. Biol., 23, 1123-1126.