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Volumn 73, Issue 4-5, 1999, Pages 274-281

Doxorubicin induces male germ cell apoptosis in rats

Author keywords

Apoptosis Testicular toxicity; Doxorubicin

Indexed keywords

DOXORUBICIN;

EID: 0032782946     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050617     Document Type: Article
Times cited : (67)

References (45)
  • 1
    • 0020614249 scopus 로고
    • Induction of sister-chromatid exchanges by chemotherapeutic drugs in spermatogonia of mice: Effects of procarbazine, adriamycin, cyclophosphamide and mitomycin C
    • Abraham SK, Fränz J (1983) Induction of sister-chromatid exchanges by chemotherapeutic drugs in spermatogonia of mice: effects of procarbazine, adriamycin, cyclophosphamide and mitomycin C. Mutat Res 108: 373-381
    • (1983) Mutat Res , vol.108 , pp. 373-381
    • Abraham, S.K.1    Fränz, J.2
  • 2
    • 0026561490 scopus 로고
    • The nature of cytotoxic drug-induced cell death in murine intestinal crypts
    • Anilkumar TV, Sarraf CE, Hunt T, Alison MR (1992) The nature of cytotoxic drug-induced cell death in murine intestinal crypts. Br J Cancer 65: 552-558
    • (1992) Br J Cancer , vol.65 , pp. 552-558
    • Anilkumar, T.V.1    Sarraf, C.E.2    Hunt, T.3    Alison, M.R.4
  • 3
    • 0027191429 scopus 로고
    • In situ end-labeling detects DNA strand breaks in apoptosis and other physiological and pathological states
    • Ansari B, Coates PJ, Greenstein BD, Hall PA (1993) In situ end-labeling detects DNA strand breaks in apoptosis and other physiological and pathological states. J Pathol 170: 1-8
    • (1993) J Pathol , vol.170 , pp. 1-8
    • Ansari, B.1    Coates, P.J.2    Greenstein, B.D.3    Hall, P.A.4
  • 4
    • 0019132013 scopus 로고
    • The genotoxic effects of adriamycin in somatic and germinal cells of the mouse
    • Au WW, Hsu TC (1980) The genotoxic effects of adriamycin in somatic and germinal cells of the mouse. Mutat Res 79: 351-361
    • (1980) Mutat Res , vol.79 , pp. 351-361
    • Au, W.W.1    Hsu, T.C.2
  • 6
    • 0029926356 scopus 로고    scopus 로고
    • Spontaneous germ cell death in the testis of the adult rat takes the form of apoptosis: Re-evaluation of cell types that exhibit the ability to die during spermatogenesis
    • Blanco-Rodríguez J, Martínez-García C (1996) Spontaneous germ cell death in the testis of the adult rat takes the form of apoptosis: re-evaluation of cell types that exhibit the ability to die during spermatogenesis. Cell Prolif 29: 13-31.
    • (1996) Cell Prolif , vol.29 , pp. 13-31
    • Blanco-Rodríguez, J.1    Martínez-García, C.2
  • 8
    • 0030958857 scopus 로고    scopus 로고
    • Induction of apoptosis in the germ cells of adult male rats after exposure to cyclophosphamide
    • Cai L, Hales BF, Robaire B (1997) Induction of apoptosis in the germ cells of adult male rats after exposure to cyclophosphamide. Biol Reprod 56: 1490-1497
    • (1997) Biol Reprod , vol.56 , pp. 1490-1497
    • Cai, L.1    Hales, B.F.2    Robaire, B.3
  • 10
    • 0002406825 scopus 로고
    • Duration of the cycle of the seminiferous epithelium of normal, hypophysectomized and hypophysectomized-hormone treated albino rat
    • Clemont Y, Harvey C (1965) Duration of the cycle of the seminiferous epithelium of normal, hypophysectomized and hypophysectomized-hormone treated albino rat. Endocrinology 76: 80-89
    • (1965) Endocrinology , vol.76 , pp. 80-89
    • Clemont, Y.1    Harvey, C.2
  • 11
    • 0026555808 scopus 로고
    • Internucleosomal DNA cleavage should not be the sole criterion of identifying apoptosis
    • Collins RJ, Harmon BV, Globe' GC, Kerr JFR (1992) Internucleosomal DNA cleavage should not be the sole criterion of identifying apoptosis. Int J Radiat Biol 61: 451-453
    • (1992) Int J Radiat Biol , vol.61 , pp. 451-453
    • Collins, R.J.1    Harmon, B.V.2    Globe', G.C.3    Kerr, J.F.R.4
  • 13
    • 0029935682 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
    • Friesen C, Herr I, Krammer PH, Debatin KM (1996) Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nature Med 2: 574-577
    • (1996) Nature Med , vol.2 , pp. 574-577
    • Friesen, C.1    Herr, I.2    Krammer, P.H.3    Debatin, K.M.4
  • 14
    • 0029294613 scopus 로고
    • In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note
    • Grasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, Bukowska K, Bursch W, Schulte-Hermann R (1995) In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 21: 1465-1468
    • (1995) Hepatology , vol.21 , pp. 1465-1468
    • Grasl-Kraupp, B.1    Ruttkay-Nedecky, B.2    Koudelka, H.3    Bukowska, K.4    Bursch, W.5    Schulte-Hermann, R.6
  • 15
    • 0025127568 scopus 로고
    • Quantitative and qualitative characteristics of the stages and transitions in the cycle of the rat seminiferous epithelium: Light microscopic observations of perfusion-fixed and plastic-embedded testes
    • Hess RA (1990) Quantitative and qualitative characteristics of the stages and transitions in the cycle of the rat seminiferous epithelium: light microscopic observations of perfusion-fixed and plastic-embedded testes. Biol Reprod 43: 525-542
    • (1990) Biol Reprod , vol.43 , pp. 525-542
    • Hess, R.A.1
  • 16
    • 0029120419 scopus 로고
    • Effects of adriamycin, an anticancer drug showing testicular toxicity, on fertility in male rats
    • 1995
    • Imahie H, Adachi T, Nakagawa Y, Nagasaki T, Yamamura T, Hori M (1995) Effects of adriamycin, an anticancer drug showing testicular toxicity, on fertility in male rats. J Toxicol Sci 20: 183-193 (1995)
    • (1995) J Toxicol Sci , vol.20 , pp. 183-193
    • Imahie, H.1    Adachi, T.2    Nakagawa, Y.3    Nagasaki, T.4    Yamamura, T.5    Hori, M.6
  • 17
    • 0020680301 scopus 로고
    • Adriamycin and daunomycin induce interstrand DNA crosslinks in Hela S3 cells
    • Knopa J (1983) Adriamycin and daunomycin induce interstrand DNA crosslinks in Hela S3 cells. Biochem Biophys Res Commun 110: 819-826
    • (1983) Biochem Biophys Res Commun , vol.110 , pp. 819-826
    • Knopa, J.1
  • 18
    • 0023819810 scopus 로고
    • 2 block induced by DNA crosslinking agents and its possible consequences
    • 2 block induced by DNA crosslinking agents and its possible consequences. Biochem Pharmacol 37: 2303-2309
    • (1988) Biochem Pharmacol , vol.37 , pp. 2303-2309
    • Konopa, J.1
  • 19
    • 0020666112 scopus 로고
    • Meiotic micronuclei induced by adriamycin in male rats
    • Lähdetie J (1983) Meiotic micronuclei induced by adriamycin in male rats. Mutat Res 119: 79-82
    • (1983) Mutat Res , vol.119 , pp. 79-82
    • Lähdetie, J.1
  • 20
    • 0027944143 scopus 로고
    • Etoposide (VP16) is a potent inducer of micronuclei in male rat meiosis: Spermatid micronucleus test and DNA flow cytometry after etoposide treatment
    • Lähdetie J, Keiski A, Suutari A, Toppari J (1994) Etoposide (VP16) is a potent inducer of micronuclei in male rat meiosis: spermatid micronucleus test and DNA flow cytometry after etoposide treatment. Environ Mol Mutagen 24: 192-202
    • (1994) Environ Mol Mutagen , vol.24 , pp. 192-202
    • Lähdetie, J.1    Keiski, A.2    Suutari, A.3    Toppari, J.4
  • 21
    • 0030890609 scopus 로고    scopus 로고
    • The Fas system is a key regulator of germ cell apoptosis in the testis
    • Lee J, Richburg JH, Younkin SC, Boekelheide K (1997) The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology 138: 2081-2088
    • (1997) Endocrinology , vol.138 , pp. 2081-2088
    • Lee, J.1    Richburg, J.H.2    Younkin, S.C.3    Boekelheide, K.4
  • 22
    • 0027278808 scopus 로고
    • Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells
    • Ling YH, Preibe W, Perez-Soler R (1993) Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells. Cancer Res 53: 1845-1852
    • (1993) Cancer Res , vol.53 , pp. 1845-1852
    • Ling, Y.H.1    Preibe, W.2    Perez-Soler, R.3
  • 23
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, Housman DE (1993) p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 24
    • 0022509062 scopus 로고
    • Testicular cytotoxicity of intravenous doxorubicin in rats
    • Lui RC, LaRegina MC, Herbold DR, Johnson FE (1986) Testicular cytotoxicity of intravenous doxorubicin in rats. J Urol 136: 940-943
    • (1986) J Urol , vol.136 , pp. 940-943
    • Lui, R.C.1    LaRegina, M.C.2    Herbold, D.R.3    Johnson, F.E.4
  • 26
    • 0022401762 scopus 로고
    • Long-term infertility and dominant lethal mutations in male mice treated with adriamycin
    • Meistrich ML, Goldstein LS, Wyrobek AJ (1985) Long-term infertility and dominant lethal mutations in male mice treated with adriamycin, Mutat Res 152: 53-65
    • (1985) Mutat Res , vol.152 , pp. 53-65
    • Meistrich, M.L.1    Goldstein, L.S.2    Wyrobek, A.J.3
  • 28
    • 0031422863 scopus 로고    scopus 로고
    • Spermatogenic cell apoptosis induced by mitomycin C in the mouse testis
    • Nakagawa S, Nakamura N, Fujioka M, Mori C (1997) Spermatogenic cell apoptosis induced by mitomycin C in the mouse testis. Toxicol Appl Pharmacol 147: 204-213
    • (1997) Toxicol Appl Pharmacol , vol.147 , pp. 204-213
    • Nakagawa, S.1    Nakamura, N.2    Fujioka, M.3    Mori, C.4
  • 30
    • 0017810314 scopus 로고
    • Biochemical studies of the rat seminiferous epithelial wave: DNA and RNA syntheses and effects of adriamycin
    • Parvinen LM, Parvinen M (1978) Biochemical studies of the rat seminiferous epithelial wave: DNA and RNA syntheses and effects of adriamycin. Ann Biol Biochem Biophys 18: 585-594
    • (1978) Ann Biol Biochem Biophys , vol.18 , pp. 585-594
    • Parvinen, L.M.1    Parvinen, M.2
  • 31
    • 0030694255 scopus 로고    scopus 로고
    • Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction
    • Perez GI, Knudson CM, Leykin L, Korsmeyer SJ, Tilly JL (1997) Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nature Med 3: 1228-1232
    • (1997) Nature Med , vol.3 , pp. 1228-1232
    • Perez, G.I.1    Knudson, C.M.2    Leykin, L.3    Korsmeyer, S.J.4    Tilly, J.L.5
  • 32
    • 0002605506 scopus 로고
    • Toxicity of free radical forming anticancer agents
    • Powis G, Hacker MP (eds) Pergamon Press, New York
    • Powis G (1991) Toxicity of free radical forming anticancer agents. In: Powis G, Hacker MP (eds) The toxicity of anticancer drugs. Pergamon Press, New York, pp.106-151
    • (1991) The Toxicity of Anticancer Drugs , pp. 106-151
    • Powis, G.1
  • 33
    • 0030975776 scopus 로고    scopus 로고
    • An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis
    • Rodriguez I, Ody C, Araki K, Garcia I, Vassalli P (1997) An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis. EMBO J 16: 2262-2270
    • (1997) EMBO J , vol.16 , pp. 2262-2270
    • Rodriguez, I.1    Ody, C.2    Araki, K.3    Garcia, I.4    Vassalli, P.5
  • 34
    • 0025947030 scopus 로고
    • Short-term morphological response of the rat testis to administration of five chemotherapeutic agents
    • Russell LD, Russell JA (1991) Short-term morphological response of the rat testis to administration of five chemotherapeutic agents. Am J Anat 192: 142-168
    • (1991) Am J Anat , vol.192 , pp. 142-168
    • Russell, L.D.1    Russell, J.A.2
  • 35
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • Schwartzman RA, Cidlowski JA (1993) Apoptosis: the biochemistry and molecular biology of programmed cell death. Endocrine Rev 14: 133-151
    • (1993) Endocrine Rev , vol.14 , pp. 133-151
    • Schwartzman, R.A.1    Cidlowski, J.A.2
  • 36
    • 0019433755 scopus 로고
    • The effects of postoperative adjuvant chemotherapy and radiotherapy on testicular function in men undergoing treatment for soft tissue sarcoma
    • Shamberger RC, Sherins RJ, Rosenberg SA (1981) The effects of postoperative adjuvant chemotherapy and radiotherapy on testicular function in men undergoing treatment for soft tissue sarcoma. Cancer 47: 2368-2374
    • (1981) Cancer , vol.47 , pp. 2368-2374
    • Shamberger, R.C.1    Sherins, R.J.2    Rosenberg, S.A.3
  • 37
    • 15444344746 scopus 로고    scopus 로고
    • Significance of apoptosis in the temporal and stage-specific loss of germ cells in the adult rat after gonadotropin deprivation
    • Sinha Hikim AP, Rajavashisth TB, Sinha Hikim I, Lue Y, Bonavera JJ, Leung A, Wang C, Swerdloff RS (1997) Significance of apoptosis in the temporal and stage-specific loss of germ cells in the adult rat after gonadotropin deprivation. Biol Reprod 57: 1193-1201
    • (1997) Biol Reprod , vol.57 , pp. 1193-1201
    • Sinha Hikim, A.P.1    Rajavashisth, T.B.2    Hikim S. I3    Lue, Y.4    Bonavera, J.J.5    Leung, A.6    Wang, C.7    Swerdloff, R.S.8
  • 38
    • 0027237540 scopus 로고
    • Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumor cells
    • Skladanowski A, Konopa J (1993) Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumor cells. Biochem Pharmacol 46: 375-382
    • (1993) Biochem Pharmacol , vol.46 , pp. 375-382
    • Skladanowski, A.1    Konopa, J.2
  • 39
    • 0000457381 scopus 로고
    • Preparation of genomic DNA from mammalian tissue
    • Ausubel FM (ed) Willey, New York
    • Strauss WM (1994) Preparation of genomic DNA from mammalian tissue. In Ausubel FM (ed) Current protocols in molecular biology. Willey, New York, pp. 2.2.1-2.2.3
    • (1994) Urrent Protocols in Molecular Biology , pp. 221-223
    • Strauss, W.M.1
  • 40
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T, Takhashi T, Golstein P, Nagata S (1993) Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75: 1169-1178
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takhashi, T.2    Golstein, P.3    Nagata, S.4
  • 41
    • 0029801457 scopus 로고    scopus 로고
    • Distribution of deoxyribonuclease I (DNase I) and p53 in rat testis and their correlation with apoptosis
    • Stephan H, Polzar B, Rauch F, Zanotti S, Ulke C, Mannherz HG (1996) Distribution of deoxyribonuclease I (DNase I) and p53 in rat testis and their correlation with apoptosis. Histochem Cell Biol 106: 383-393
    • (1996) Histochem Cell Biol , vol.106 , pp. 383-393
    • Stephan, H.1    Polzar, B.2    Rauch, F.3    Zanotti, S.4    Ulke, C.5    Mannherz, H.G.6
  • 42
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 43
    • 0022442872 scopus 로고
    • Mutagen effects on rat seminiferous tubules in vitro: Induction of meiotic micronuclei by adriamycin
    • Toppari J, Lähdetie J, Härkönen P, Eerola E, Parvine M (1986) Mutagen effects on rat seminiferous tubules in vitro: induction of meiotic micronuclei by adriamycin. Mutat Res 171: 149-156
    • (1986) Mutat Res , vol.171 , pp. 149-156
    • Toppari, J.1    Lähdetie, J.2    Härkönen, P.3    Eerola, E.4    Parvine, M.5
  • 44
    • 0016156816 scopus 로고
    • The persistence of adriamycin in man and rat
    • Wilkinson PM, Mawer GE (1974) The persistence of adriamycin in man and rat. Br J Clin Pharmacol 1: 241-247
    • (1974) Br J Clin Pharmacol , vol.1 , pp. 241-247
    • Wilkinson, P.M.1    Mawer, G.E.2
  • 45
    • 0030248675 scopus 로고    scopus 로고
    • Doxorubicin-induced apoptosis in spontaneous hypertensive rats: Differential effects in heart, kidney and intestine, and inhibition by ICRF-187
    • Zhang J, Clark JR, Herman EH, Ferrans V (1996) Doxorubicin-induced apoptosis in spontaneous hypertensive rats: differential effects in heart, kidney and intestine, and inhibition by ICRF-187. J MolCell Cardiol 28: 1931-1943
    • (1996) J Molcell Cardiol , vol.28 , pp. 1931-1943
    • Zhang, J.1    Clark, J.R.2    Herman, E.H.3    Ferrans, V.4


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