Somatostatin and octreotide modulate the function of Kupffer cells in liver cirrhosis

Regulatory Peptides

Volumn 79, Issue 2-3, 1999, Pages 117-124

  Chao, Tzu Chieh ^a   Chao, Hsiao Hsiang ^a   Lin, Jen Der ^a   Chen, Miin Fu ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Carbon tetrachloride; Hydrogen peroxide; Macrophages; Nitric oxide; Tumor necrosis factor

Indexed keywords

CARBON TETRACHLORIDE; HYDROGEN PEROXIDE; NITRIC OXIDE; OCTREOTIDE; SOMATOSTATIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; KUPFFER CELL; LIVER CIRRHOSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CELLS, CULTURED; HORMONE ANTAGONISTS; HORMONES; HYDROGEN PEROXIDE; KUPFFER CELLS; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; NITRIC OXIDE; OCTREOTIDE; RATS; RATS, SPRAGUE-DAWLEY; SOMATOSTATIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032781868     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(98)00150-5     Document Type: Article

References (75)

1. Bouwens L., Baekeland M., Wisse E. Importance of local proliferation in the expanding Kupffer cell population of rat liver after zymosan stimulation and partial hepatectomy. Hepatology. 4:1984;213-219.
2. Nolan J.P. Endotoxin, reticuloendothelial function, and liver injury. Hepatology. 1:1981;458-465.
3. Jacob A.I., Coldberg P.K., Bllom B.S., Degenshein G.A., Kozinn P.J. Endotoxin and bacteria in portal blood. Gastroenterology. 72:1977;1268.
4. Phillips N.C. Kupffer cells and liver metastasis: optimization and limitation of activation of tumoricidal activity. Cancer Metastasis Rev. 8:1989;231-252.
5. Roh M.S., Wang L., Oyedeji C., Leroux M.E., Curley S.A., Pollock R.E., Klostergaard J. Human Kupffer cells are cytotoxic against human colon adenocarcinoma. Surgery. 108:1990;400-405.
6. Zhang W., Arii S., Sasaoki T., Adachi Y., Funaki N., Higashitsuji H., Fujita S., Furukawa M., Mise M., Ishiguro S., Kitao T., Tobe T., Naito M. The role of Kupffer cells in the surveillance of tumor growth in the liver. J Surg Res. 55:1993;140-146.
7. Johnkoski J.A., Tzung S.-P., Doerr R.J., Cohen S.A. Hepatic metastasis alters the immune function of murine liver nonparenchymal cells. Arch Surg. 127:1992;1325-1329.
8. Bayon L.G., Izquierdo M.A., Sirovich I., van Rooijen N., Beelen R.H.J. Role of Kupffer cells in arresting circulating tumor cells and controlling metastatic growth in the liver. Hepatology. 23:1996;1224-1231.
9. Fausto N., Laird A.D., Webber E.M. Role of growth factors and cytokines in hepatic regeneration. FASEB J. 9:1995;1527-1536.
10. Funaki N., Arii S., Monden K., Itai S., Sasaoki T., Adachi Y., Higashitsuji H., Tanaka J., Tobe T. Chemical mediators released from hepatic macrophages in primary culture - Basic characteristics of human hepatic macrophages and changes in liver cirrhosis. J Surg Res. 54:1993;222-229.
11. Saito H., Kurose I., Ebinuma H., Fukumura D., Higuchi H., Atsukawa K., Tada S., Kimura H., Yonei Y., Masuda T., Miura S., Ishii H. Kupffer cell-mediated cytotoxicity against hepatoma cells occurs through production of nitric oxide and adhesion via ICMA-1/CD18. Int Immunol. 8:1996;1165-1172.
12. Fukumura D., Yonei Y., Kurose I., Saito H., Ohishi T., Higuchi H., Miura S., Kato S., Kimura H., Ebinuma H., Ishii H. Role of nitric oxide in Kupffer cell-mediated hepatoma cell cytotoxicity in vitro and ex vivo. Hepatology. 24:1996;141-149.
13. Reichlin S. Somatostatin. New Engl J Med. 309:1983;1495-1501.
14. Reichlin S. Somatostatin. New Engl J Med. 309:1983;1556-1561.
15. Blum A.M., Metwali A., Mathew R.C., Cook G., Elliott D., Weinstock J.V. Granuloma T lymphocytes in murine schistosomiasis mansoni have somatostatin receptors and respond to somatostatin with decreased IFN-gamma secretion. J Immunol. 149:1992;3621-3626.
16. Muscettola M., Grasso G. Somatostatin and vasoactive intestinal peptide reduce interferon gamma production by human peripheral blood mononuclear cells. Immunobiology. 180:1990;419-430.
17. Yousefi S., Ghazinouri A., Vaziri N., Tilles J., Carandanz G., Cesario T. The effect of somatostatin on the production of human interferons by mononuclear cells. Pro Soc Exp Biol Med. 194:1990;114-118.
18. Niedermuhlbichler M., Wiedermann C.J. Suppression of superoxide release from human monocytes by somatostatin-related peptides. Regul Pept. 41:1992;39-47.
19. Bermudez L.E., Wu M., Young L.S. Effect of stress-related hormones on macrophage receptors and response to tumor necrosis factor. Lymphokine Res. 9:1990;137-145.
20. Chao T.-C., Cheng H.-P., Walter R.J. Somatostatin and macrophage function: Modulation of hydrogen peroxide, nitric oxide and tumor necrosis factor release. Regul Pept. 58:1995;1-10.
21. Kimata H., Yoshida A., Ishioka C., Mikawa H. Differential effect of vasoactive intestinal peptide, somatostatin, and substance P on human IgE and IgG subclass production (published erratum appears in Cell Immunol 1993(July);149(2):450). Cell Immunol. 144:1992;429-442.
22. Kimata H., Yoshida A., Fujimoto M., Mikawa H. Effect of vasoactive intestinal peptide, somatostatin, and substance P on spontaneous IgE and IgG4 production in atopic patients. J Immunol. 150:1993;4630-4640.
23. Stanisz A.M., Befus D., Bienenstock J. Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferations by lymphocytes from Peyer's patches, mesenteric lymph nodes, and spleen. J Immunol. 136:1986;152-156.
24. Payan D.G., Hess C.A., Goetzl E.J. Inhibition by somatostatin of the proliferation of T-lymphocytes and Molt-4 lymphocytes. Cell Immunol. 84:1984;433-438.
25. Malec P., Zeman K., Markiewicz K., Tchorzewski H., Nowak Z. Short-term somatostatin infusion affects T lymphocyte responsiveness in humans. Immunopharmacology. 17:1989;45-49.
26. Nio D.A., Moylan R.N., Roche J.K. Modulation of T lymphocyte function by neuropeptides. J Immunol. 150:1993;5281-5288.
27. Johansson O., Sandberg G. Effect of the neuropeptides beta-MSH, neurotensin, NPY, PHI, somatostatin and substance P on proliferation of lymphocytes in vitro. Acta Physiol Scand. 137:1989;107-111.
28. Foris G., Gyimesi E., Komaromi I. The mechanism of antibody-dependent cellular cytotoxicity stimulation by somatostatin in rat peritoneal macrophages. Cell Immunol. 90:1985;217-225.
29. van Tol E.A.F., Verspaget H.W., Lamers C.B.H.W. Neuropeptide regulation of cell-mediated cytotoxicity against human tumor cells. Neuropeptides. 16:1990;25-32.
30. Harris A.G. Octreotide in the treatment of disorders of the gastrointestinal system. Drug Invest. 4(Suppl 3):1992;1-54.
31. Paran H., Neufeld D., Kaplan O., Klausner J., Freund U. Octreotide for treatment of postoperative alimentary tract fistulas. World J Surg. 19:1995;430-434.
32. Rosenberg L., Barkun A.N., Denis M.H., Pollak M. Low dose octreotide and tamoxifen in the treatment of adenocarcinoma of the pancreas. Cancer. 75:1995;23-28.
33. Cascinu S., Del Ferro E., Catalano G. A randomized trial of octreotide vs best supportive care only in advanced gastrointestinal cancer patients refractory to chemotherapy. Br J Cancer. 71:1995;97-101.
34. Di Leo A., Ferrari L., Bajetta E., Bartoli C., Vicario G., Moglia D., Miceli R., Callegari M., Bono A. Biological and clinical evaluation of Lanreotide (BIM 23014), a somatostatin analogue, in the treatment of advanced breast cancer. Breast Cancer Res Treat. 34:1995;237-244.
35. Nott D.M., Baxter J.N., Yates J., Grime J.S., Day D.W., Cooke T.G., Jenkins S.A. Effects of a somatostatin analogue (SMS 201-995) on the growth and development of hepatic tumor derived by intraportal injection of Walker cells in the rat. Br J Surg. 76:1989;1149-1151.
36. Qin Y., Schally A.V., Willems G. Treatment of liver metastases of human colon cancers in nude mice with somatostatin analogue RC-60. Int J Cancer. 52:1992;791-796.
37. Stewart G.J., Lawson J.A., Morris D.L. Octreotide inhibits development of hepatic metastases from a human colonic cancer cell line. Br J Surg. 81:1994;1332.
38. Davies N., Kynaston H., Yates J., Nott D.M., Nash J., Taylor B.A., Jenkins S.A. Octreotide inhibits the growth and development of three of experimental liver metastases. Br J Surg. 82:1995;840-843.
39. Kew M.C., Popper H. Relationship between hepatocellular carcinoma and cirrhosis. Semin Liver Dis. 4:1984;136-146.
40. Rikkers LF. Surgical complications of cirrhosis and portal hypertension. In: Sabinston DC Jr, editor. Textbook of Surgery, 14 ed. Philadelphia: W.B. Saunders Company, 1991:1015-29.
41. Laskin D.L., Sirak A.A., Pitaro A.M., Laskin J.D. Functional and biochemical properties of rat Kupffer cells and peritoneal macrophages. J Leukocyte Biol. 44:1988;71-78.
42. Holdstock G., Leslile B., Hill S., Tanner A., Wright R. Monocyte function in cirrhosis. J Clin Pathol. 35:1982;972-979.
43. Hassner A., Kletter Y., Shlag D., Yedvab M., Aronson M., Shibolet S. Impaired monocyte function in liver cirrhosis. Br Med J. 282:1981;1262-1263.
44. Funaki N., Arii S., Adachi Y., Higashitsuji H., Tanaka J., Tobe T. Superoxide release by primary-cultured human hepatic macrophages and peripheral monocytes from patients with normal and cirrhotic livers. Scand J Clin Lab Invest. 53:1993;339-346.
45. Chao T.-C., Chao H.-H., Chen M.-F., Lin J.-D. Somatostatin modulates the function of Kupffer cells. Regul Pept. 69:1997;143-149.
46. Chao T.-C., Van Alten P.J., Walter R.J. Steroid sex hormones and macrophage function: Modulation of reactive oxygen intermediates and nitrite release. Am J Reprod Immunol. 32:1994;43-52.
47. Proctor E., Chatamra K. High yield micronodular cirrhosis in the rat. Gastroenterology. 83:1982;1183-1190.
48. Stuehr D.J., Marletta M.A. Synthesis of nitrite and nitrate in murine macrophage cell lines. Cancer Res. 47:1987;5590-5594.
49. Ding A.H., Nathan C.F., Stuehr D.J. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. J Immunol. 141:1988;2407-2412.
50. 15N]nitrate in biological fluids. Anal Biochem. 126:1982;131-138.
51. Pick E. Microassays for superoxide and hydrogen peroxide production and nitroblue tetrazolium reduction using an enzyme immunoassay microplate reader. Methods Enzymol. 132:1986;407-421.
52. Reisine T. Somatostatin receptors. Am J Physiol. 269:1995;G813-G820.
53. Lamberts S.W.J., van der Lely A.-J., de Herder W.W., Hofland U. Octreotide. New Engl J Med. 334:1996;246-254.
54. Nevens F., Van Steenbergen W., Yap S.H., Fevery J. Assessment of variceal pressure by continuous non-invasive endoscopic registration: a placebo controlled evaluation of the effect of terlipressin and octreotide. Gut. 38:1996;129-134.
55. Gaudin C., Moreau R., Champigneulle B., Soubrane O., Kleber G., Lebrec D. Short-term cardiovascular effects of somatostatin in patients with cirrhosis. Liver. 15:1995;236-241.
56. Lin H.-C., Tsai Y.-T., Yang M.C.M., Lee F.-Y., Hou M.-C., Chen L.-S., Lee S.-D. Effect of octreotide on total effective vascular compliance in patients with posthepatic cirrhosis. J Hepatol. 24:1996;81-87.
57. Nevens F., Sprengers D., Fevery J. The effect of different doses of a bolus injection of somatostatin combined with a slow infusion on transmural oesophageal variceal pressure in patients with cirrhosis. J Hepatol. 20:1994;27-31.
58. Jenkins S.A., Devitt P., Day D.W., Baxter J.N., Shilds R. Effects of somatostatin on hepatic haemodynamics in the cirrhotic rat. Digestion. 33:1986;126-134.
59. Cerini R., Lee S.S., Hadengue A., Koshy A., Girod C., Lebrec D. Circulatory effects of somatostatin analogue in two continuous rat models of portal hypertension. Gastroenterology. 94:1988;703-708.
60. Kravetz D., Bosch J., Arderiu M.T.et al. Effects of somatostatin on splanchnic hemodynamics and plasma glucagon in portal hypertensive rats. Am J Physiol. 254:1988;G322-G328.
61. Pizcueta M.P., Garcia-Pagan J.C., Fernandez M., Casamitjana R., Bosch J., Rodes J. Glucagon hinders the effects of somatostatin on portal hypertension. A study in rats with partial portal vein ligation. Gastroenterology. 101:1991;1710-1715.
62. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6:1992;3051-3064.
63. Yousefi S., Vaziri N., Carandang G., Le W., Yamamoto R., Granger G., Ocariz J., Cesario T. The paradoxical effects of somatostatin on the bioactivity and production of cytotoxins derived from human peripheral blood mononuclear cells. Br J Cancer. 64:1991;243-246.
64. Karalis K., Mastorakos G., Chrousos G.P., Tolis G. Somatostatin analogues suppress the inflammatory reaction in vivo. J Clin Invest. 93:1994;2000-2006.
65. Blum A.M., Metwali A., Cook G., Mathew R.C., Elliott D., Weinstock J.V. Substance P modulates antigen-induced, IFN-gamma production in murine schistosomiasis mansoni. J Immunol. 151:1993;225-233.
66. Baxter J.N., Jenkins S.A., Day D.W., Shields R. Effects of a somatostatin analogue (SMS 201-995) on hepatic and splenic reticulo-endothelial function in the rat. Br J Surg. 72:1985;1005-1008.
67. Davies N., Kynaston H., Yates J., Taylor B.A., Jenkins S.A. Octreotide, the reticulo-endothelial system, and experimental liver tumor. Gut. 36:1995;610-614.
68. Efendic S., Grill V., Luft R. Inhibition by somatostatin of glucose induced 3′5-monophosphate (cylic AMP) accumulation and insulin release in isolated pancreatic islets of the rat. FEBS Lett. 55:1975;131-133.
69. Gespach C., Dupont C., Bataille D., Rosselin G. Selective inhibition by somatostatin of cyclic AMP production in rat gastric glands. FEBS Lett. 114:1980;247-252.
70. Chneiweiss H., Glowinski J., Premont J. Modulation by monoamine of somatostatin-sensitive adenylate cyclase on neuronal and glial cells from the mouse brain in primary cultures. J Neurochem. 44:1985;1825-1831.
71. Segura J.J., Guerrero J.M., Goberna R., Calvo J.R. Somatostatin inhibition of VIP- and isoproterenol-stimulated cyclic AMP production in rat peritoneal macrophages. Neuropeptides. 23:1992;39-43.
72. 2 and cyclic nucleotides. J Immunol. 141:1988;2388-2393.
73. Endres S., Fulle H.-J., Sinha B., Stoll D., Dinarello C.A., Gerzer R., Weber P.C. Cyclic nucleotides differentially regulate the synthesis of tumor necrosis factor-α and interleukin-1β by human mononuclear cells. Immunology. 72:1991;56-60.
74. Ding A.H., Nathan C.F. Trace levels of bacterial lipopolysaccharide prevent interferon-gamma or tumor necrosis factor-α from enhancing mouse peritoneal macrophage respiratory burst capacity. J Immunol. 139:1987;1971-1977.
75. Channon J.Y., Leslie C.C., Johnston R.B. Jr. Zymosan-stimulated production of phosphatidic acid by macrophages: Relationship to release of superoxide anion and inhibition by agents that increase intracellular cyclic AMP. J Leukocyte Biol. 41:1987;450453.