메뉴 건너뛰기




Volumn 14, Issue 7, 1999, Pages 411-417

Molecular heterogeneity in medulloblastoma with implications for differing tumor biology

Author keywords

[No Author keywords available]

Indexed keywords

BETA TUBULIN; CALBINDIN; CALPHOSTIN C; CYCLINE; DIACYLGLYCEROL; DNA; ENZYME INHIBITOR; GENE PRODUCT; KI 67 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN RECEPTOR; PHORBOL ESTER; PHOSPHOLIPID; PHOSPHOTRANSFERASE; PROTEIN KINASE C; PROTEIN P53; PROTEIN SERINE KINASE;

EID: 0032781682     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/088307389901400701     Document Type: Review
Times cited : (6)

References (78)
  • 2
    • 0001587471 scopus 로고
    • Medulloblastoma cerebelli; a common type of midcerebellar glioma of childhood
    • Bailey P, Cushing H: Medulloblastoma cerebelli; a common type of midcerebellar glioma of childhood. Arch Neurol Psychiatry 1925;14:192.
    • (1925) Arch Neurol Psychiatry , vol.14 , pp. 192
    • Bailey, P.1    Cushing, H.2
  • 3
    • 0022337034 scopus 로고
    • Revision of the World Health Organization classification of brain tumors for childhood brain tumors
    • Rorke LB, Gilles FH, Davis RL, et al: Revision of the World Health Organization classification of brain tumors for childhood brain tumors. Cancer 1985;56:1869-1886.
    • (1985) Cancer , vol.56 , pp. 1869-1886
    • Rorke, L.B.1    Gilles, F.H.2    Davis, R.L.3
  • 4
    • 0027186145 scopus 로고
    • Expression of neuronal and glial polypeptides during histogenesis of the human cerebellar cortex including observations on the dentate nucleus
    • Yachnis AT, Rocke LB, Lee VM-Y, et al: Expression of neuronal and glial polypeptides during histogenesis of the human cerebellar cortex including observations on the dentate nucleus. J Comp Neurol 1993;334:356-369.
    • (1993) J Comp Neurol , vol.334 , pp. 356-369
    • Yachnis, A.T.1    Rocke, L.B.2    Lee, V.M.-Y.3
  • 5
    • 0004546026 scopus 로고
    • Neuronal survival and synapse formation
    • Kandel ER, Schwartz JH, Jessell TM (eds). New York, Elsevier
    • Jessel TM: Neuronal survival and synapse formation, in Kandel ER, Schwartz JH, Jessell TM (eds): Principles of Neural Science. New York, Elsevier, 1991, pp 929-944.
    • (1991) Principles of Neural Science , pp. 929-944
    • Jessel, T.M.1
  • 8
    • 0027992102 scopus 로고
    • Neuron associated class III β tubulin, tau and MAP2 in the D283-Med cell line and in primary explants of human medulloblastoma
    • Vinores SDA, Herman MM, Katsetos CD, et al: Neuron associated class III β tubulin, tau and MAP2 in the D283-Med cell line and in primary explants of human medulloblastoma. Histochem J 1994;26: 678-685.
    • (1994) Histochem J , vol.26 , pp. 678-685
    • Vinores, S.D.A.1    Herman, M.M.2    Katsetos, C.D.3
  • 9
    • 0026474849 scopus 로고
    • Medulloblastoma and related primitive neuroectodermal tumors of childhood recapitulate molecular milestones in the maturation of neuroblasts
    • Trojanowski JQ, Tohyama T, Lee VM-Y: Medulloblastoma and related primitive neuroectodermal tumors of childhood recapitulate molecular milestones in the maturation of neuroblasts. Mol Chem Neuropathol 1992;17:121-135.
    • (1992) Mol Chem Neuropathol , vol.17 , pp. 121-135
    • Trojanowski, J.Q.1    Tohyama, T.2    Lee, V.M.-Y.3
  • 10
    • 0023847681 scopus 로고
    • Structural chromosomal abnormalities in human medulloblastoma
    • Bigner SH, Mark J, Friedman HS, et al: Structural chromosomal abnormalities in human medulloblastoma Cancer Genet Cytogenet 1988;30:91-101.
    • (1988) Cancer Genet Cytogenet , vol.30 , pp. 91-101
    • Bigner, S.H.1    Mark, J.2    Friedman, H.S.3
  • 11
    • 0025143557 scopus 로고
    • Loss of genetic information in central nervous system tumors common to children and young adults
    • James CD, Ju HE, Carlbom E, et al: Loss of genetic information in central nervous system tumors common to children and young adults. Genes Chromosomes Cancer 1990;2:94-102.
    • (1990) Genes Chromosomes Cancer , vol.2 , pp. 94-102
    • James, C.D.1    Ju, H.E.2    Carlbom, E.3
  • 12
    • 0026513426 scopus 로고
    • Involvement of multiple 17p loci in medulloblastoma tumorigenesis
    • Cogen PH, Daneshvar L, Metzger AK, et al: Involvement of multiple 17p loci in medulloblastoma tumorigenesis. Am J Hum Genet 1992;50:584-689.
    • (1992) Am J Hum Genet , vol.50 , pp. 584-689
    • Cogen, P.H.1    Daneshvar, L.2    Metzger, A.K.3
  • 13
    • 0026634161 scopus 로고
    • Evidence for a 17p tumor related locus distinct from p53 in pediatric primitive neuroectodermal tumors
    • Biegel JA, Burk CD, Barr FG, et al: Evidence for a 17p tumor related locus distinct from p53 in pediatric primitive neuroectodermal tumors. Cancer Res 1992;52:3391-3395.
    • (1992) Cancer Res , vol.52 , pp. 3391-3395
    • Biegel, J.A.1    Burk, C.D.2    Barr, F.G.3
  • 14
    • 0026087925 scopus 로고
    • Loss of heterozygosity on 6q, 16q, and 17p in human central nervous system primitive neuroectodermal tumors
    • Thomas GA, Raffel C: Loss of heterozygosity on 6q, 16q, and 17p in human central nervous system primitive neuroectodermal tumors. Cancer Res 1991;51:639-643.
    • (1991) Cancer Res , vol.51 , pp. 639-643
    • Thomas, G.A.1    Raffel, C.2
  • 15
    • 0028172248 scopus 로고
    • p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma
    • Adesina AM, Nalbantoglu J, Cavenee WK: p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res 1994;54:5649-5651.
    • (1994) Cancer Res , vol.54 , pp. 5649-5651
    • Adesina, A.M.1    Nalbantoglu, J.2    Cavenee, W.K.3
  • 16
    • 0025938198 scopus 로고
    • Infrequent p53 gene mutations in medulloblastomas
    • Saylors III RL, Sidransky D, Friedman HS, et al: Infrequent p53 gene mutations in medulloblastomas. Cancer Res 1991;51:4721-4723.
    • (1991) Cancer Res , vol.51 , pp. 4721-4723
    • Saylors R.L. III1    Sidransky, D.2    Friedman, H.S.3
  • 17
    • 0029031125 scopus 로고
    • Prognostic implications of chromosome 17p deletions in human medulloblastomas
    • Batra SK, McLendon RE, Koo JS, et al: Prognostic implications of chromosome 17p deletions in human medulloblastomas. J Neurooncol 1995;24:39-45.
    • (1995) J Neurooncol , vol.24 , pp. 39-45
    • Batra, S.K.1    McLendon, R.E.2    Koo, J.S.3
  • 18
    • 0030037445 scopus 로고    scopus 로고
    • Loss of heterozygosity at locus F13B on chromosome Iq in human medulloblastoma
    • Kraus JA, Koch A, Albretcht S, et al: Loss of heterozygosity at locus F13B on chromosome Iq in human medulloblastoma. Int J Cancer 1996;67:11-15.
    • (1996) Int J Cancer , vol.67 , pp. 11-15
    • Kraus, J.A.1    Koch, A.2    Albretcht, S.3
  • 19
    • 0028798253 scopus 로고
    • Correlation of loss of heterozygosity at chromosome 9q with histologic subtype in medulloblastomas
    • Schofield D, West Anthony DC, Marshal R, et al: Correlation of loss of heterozygosity at chromosome 9q with histologic subtype in medulloblastomas. Am J Pathol 1995;146:472-480.
    • (1995) Am J Pathol , vol.146 , pp. 472-480
    • Schofield, D.1    West Anthony, D.C.2    Marshal, R.3
  • 20
    • 0031002824 scopus 로고    scopus 로고
    • The nevoicl basal cell carcinoma syndrome: Genetics and mechanisms of carcinogenesis
    • Bale AE: The nevoicl basal cell carcinoma syndrome: Genetics and mechanisms of carcinogenesis. Cancer Invest 1997;15:180-186.
    • (1997) Cancer Invest , vol.15 , pp. 180-186
    • Bale, A.E.1
  • 22
    • 0030874617 scopus 로고    scopus 로고
    • Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumors
    • Vorechovsky I, Tingby O, Hartman M, et al: Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumors. Oncogene 1997;15:361-366.
    • (1997) Oncogene , vol.15 , pp. 361-366
    • Vorechovsky, I.1    Tingby, O.2    Hartman, M.3
  • 23
    • 0032080853 scopus 로고    scopus 로고
    • Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system
    • Reifenberger J, Wolter M, Weber EG, et al: Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res 1998;58:1798-1803.
    • (1998) Cancer Res , vol.58 , pp. 1798-1803
    • Reifenberger, J.1    Wolter, M.2    Weber, E.G.3
  • 24
    • 0030913169 scopus 로고    scopus 로고
    • Medulloblastomas of the desmo-plastic variant carry mutations of the human homologue of Drosophila patched
    • Pietsh T, Waha A, Koch A, et al: Medulloblastomas of the desmo-plastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res 1997;57:2085-2088.
    • (1997) Cancer Res , vol.57 , pp. 2085-2088
    • Pietsh, T.1    Waha, A.2    Koch, A.3
  • 25
    • 0032472943 scopus 로고    scopus 로고
    • The nevoid basal cell carcinoma syndrome (Gorlin syndrome) is a chromosomal instability syndrome
    • Shafei-Benaissa E, Savage JR, Babin P, et al: The nevoid basal cell carcinoma syndrome (Gorlin syndrome) is a chromosomal instability syndrome. Mutal Res 1998;397:287-292.
    • (1998) Mutal Res , vol.397 , pp. 287-292
    • Shafei-Benaissa, E.1    Savage, J.R.2    Babin, P.3
  • 26
    • 0030866154 scopus 로고    scopus 로고
    • Altered neural cell fates and medulloblastoma in mouse patched mutants
    • Goodrich LV, Milenkovic L, Higgins KM, et al: Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 1997;277:1109-1113.
    • (1997) Science , vol.277 , pp. 1109-1113
    • Goodrich, L.V.1    Milenkovic, L.2    Higgins, K.M.3
  • 28
    • 0028350888 scopus 로고
    • Germline and somatic mutations of the APC gene with turcot's syndrome and analysis of APC mutation in brain tumors
    • Mori T, Nagase H, Horrii A, et al: Germline and somatic mutations of the APC gene with Turcot's syndrome and analysis of APC mutation in brain tumors. Genes Chromosomes Cancer 1994;9:168-172.
    • (1994) Genes Chromosomes Cancer , vol.9 , pp. 168-172
    • Mori, T.1    Nagase, H.2    Horrii, A.3
  • 29
    • 0025373253 scopus 로고
    • Elevated c-myc expression in childhood medulloblastomas
    • MacGregor DN, Ziff EB: Elevated c-myc expression in childhood medulloblastomas. Pediatr Res 1990;28:63-68.
    • (1990) Pediatr Res , vol.28 , pp. 63-68
    • MacGregor, D.N.1    Ziff, E.B.2
  • 30
    • 0025334765 scopus 로고
    • Oncogene amplification in pediatric brain tumors
    • Wasson JC, Saylors III RL, Zelter P, et al: Oncogene amplification in pediatric brain tumors. Cancer Res 1990;50:2987-2990.
    • (1990) Cancer Res , vol.50 , pp. 2987-2990
    • Wasson, J.C.1    Saylors R.L. III2    Zelter, P.3
  • 31
    • 0025239307 scopus 로고
    • Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts
    • Bigner SH, Friedman SH, Vogelstein B, et al: Amplification of the c-myc gene in human medulloblastoma cell lines and xenografts. Cancer Res 1990;50:2347-2350.
    • (1990) Cancer Res , vol.50 , pp. 2347-2350
    • Bigner, S.H.1    Friedman, S.H.2    Vogelstein, B.3
  • 32
    • 0024381708 scopus 로고
    • N-myc gene expression and oncoprotein characterisation in medulloblastoma
    • Garson JA, Pemberton LF, Sheppard PW, et al: N-myc gene expression and oncoprotein characterisation in medulloblastoma. Br J Cancer 1989;59:889-894.
    • (1989) Br J Cancer , vol.59 , pp. 889-894
    • Garson, J.A.1    Pemberton, L.F.2    Sheppard, P.W.3
  • 33
    • 0024342552 scopus 로고
    • The N-ras oncogene is activated in a human medulloblastoma cell line
    • Fults D, Maness PF, Nakamura Y, et al: The N-ras oncogene is activated in a human medulloblastoma cell line. Brain Res 1989;503: 281-287.
    • (1989) Brain Res , vol.503 , pp. 281-287
    • Fults, D.1    Maness, P.F.2    Nakamura, Y.3
  • 34
    • 0028918623 scopus 로고
    • Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma
    • Gilbertson RJ, Pearson ADJ, Peryy RH, et al: Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma. Br J Cancer 1995;71:473-477.
    • (1995) Br J Cancer , vol.71 , pp. 473-477
    • Gilbertson, R.J.1    Pearson, A.D.J.2    Peryy, R.H.3
  • 35
    • 0026653052 scopus 로고
    • Protein kinase C modulation of NMDA currents: An important link for LTP induction
    • Ben-Ari Y, Anikszteijn L, Biegestovki P: Protein kinase C modulation of NMDA currents: An important link for LTP induction. Trends Neurosci 1992;15:333-339.
    • (1992) Trends Neurosci , vol.15 , pp. 333-339
    • Ben-Ari, Y.1    Anikszteijn, L.2    Biegestovki, P.3
  • 36
    • 0023874148 scopus 로고
    • Distribution of protein kinase C-like immunoreactive neurons in rat brain
    • Saito N, Kikkawa U, Nishizuka Y, et al: Distribution of protein kinase C-like immunoreactive neurons in rat brain. J Neurosci 1988;8:369-382.
    • (1988) J Neurosci , vol.8 , pp. 369-382
    • Saito, N.1    Kikkawa, U.2    Nishizuka, Y.3
  • 37
    • 0025282155 scopus 로고
    • Protein kinase C subtypes in tissues derived from neural crest
    • Koda Y, Kobayashi H, Mizki T, et al: Protein kinase C subtypes in tissues derived from neural crest. Brain Res 1990;518:334-336.
    • (1990) Brain Res , vol.518 , pp. 334-336
    • Koda, Y.1    Kobayashi, H.2    Mizki, T.3
  • 38
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y: Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992;258:607-613.
    • (1992) Science , vol.258 , pp. 607-613
    • Nishizuka, Y.1
  • 39
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka Y: The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 1988;334: 661-665.
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 40
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • Nishizuka Y: Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 1995;9:484-496.
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 41
    • 0025266685 scopus 로고
    • Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B
    • Ghosh S, Baltimore D: Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B. Nature 1990;344:678-682.
    • (1990) Nature , vol.344 , pp. 678-682
    • Ghosh, S.1    Baltimore, D.2
  • 42
    • 0027326410 scopus 로고
    • Protein kinase C alpha activates RAF-1 by direct phosphorylation
    • Kolch W, Heidecker G, Kochs G, et al: Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature 1993;364:249-252.
    • (1993) Nature , vol.364 , pp. 249-252
    • Kolch, W.1    Heidecker, G.2    Kochs, G.3
  • 43
    • 0029919551 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase by protein kinase C isotypes alpha, beta 1 and gamma but not epsilon
    • 196
    • Youg SW, Dickens M, Tavare JM: Activation of mitogen-activated protein kinase by protein kinase C isotypes alpha, beta 1 and gamma but not epsilon. FEBS Lett 196;384:181-184.
    • FEBS Lett , vol.384 , pp. 181-184
    • Youg, S.W.1    Dickens, M.2    Tavare, J.M.3
  • 44
    • 0029064245 scopus 로고
    • Protein kinase C isoform α overexpression in C6 glioma cells and its role in cell proliferation
    • Baltuch GH, Dooley NP, Rostworowski KM, et al: Protein kinase C isoform α overexpression in C6 glioma cells and its role in cell proliferation. J Neurooncol 1995;24:241-250.
    • (1995) J Neurooncol , vol.24 , pp. 241-250
    • Baltuch, G.H.1    Dooley, N.P.2    Rostworowski, K.M.3
  • 45
    • 0027292678 scopus 로고
    • Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-α and -δ and not by protein kinase C-βII, -ε, -ζ, -η
    • Mischak H, Pierce JH, Goodnight J, et al: Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-α and -δ and not by protein kinase C-βII, -ε, -ζ, -η. J Biol Chem 1993;268: 20110-20115.
    • (1993) J Biol Chem , vol.268 , pp. 20110-20115
    • Mischak, H.1    Pierce, J.H.2    Goodnight, J.3
  • 46
    • 0026472991 scopus 로고
    • Cell division arrest induced by phorbol ester in CHO overexpressing protein kinase C-δ subspecies
    • Watanabe T, Ono Y, Taniyama Y, et al: Cell division arrest induced by phorbol ester in CHO overexpressing protein kinase C-δ subspecies. Proc Natl Acad Sci USA 1992;89:10159-10163.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10159-10163
    • Watanabe, T.1    Ono, Y.2    Taniyama, Y.3
  • 47
    • 0027453494 scopus 로고
    • Protein kinase C-mediated bidirectional regulation of DNA synthesis, RB protein phosphorylation and cyclin dependent kinases in human vascular endothelial cells
    • Zhou W, Takuwa N, Kumada M, et al: Protein kinase C-mediated bidirectional regulation of DNA synthesis, RB protein phosphorylation and cyclin dependent kinases in human vascular endothelial cells. J Biol Chem 1993;268:23041-23048.
    • (1993) J Biol Chem , vol.268 , pp. 23041-23048
    • Zhou, W.1    Takuwa, N.2    Kumada, M.3
  • 49
    • 0030028790 scopus 로고    scopus 로고
    • A Grb2-associated docking protein in EGF and insulin receptor signaling
    • Holgado-Madruga M, Emlet DR, Moscatello DK, et al: A Grb2-associated docking protein in EGF and insulin receptor signaling. Nature 1996;379:560-564.
    • (1996) Nature , vol.379 , pp. 560-564
    • Holgado-Madruga, M.1    Emlet, D.R.2    Moscatello, D.K.3
  • 50
    • 0028568009 scopus 로고
    • Expression of neurotrophin receptor trk C is linked to a favorable outcome in medulloblastoma
    • Segal RA, Goumnerova LC, Kwon YK, et al: Expression of neurotrophin receptor trk C is linked to a favorable outcome in medulloblastoma.Proc Natl Acad Sci USA 1994;91:12867-12871.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12867-12871
    • Segal, R.A.1    Goumnerova, L.C.2    Kwon, Y.K.3
  • 51
    • 0031938867 scopus 로고    scopus 로고
    • Differential role for protein kinase C-mediated signaling in the proliferation of medulloblastoma cell lines
    • Adesina AM, Dooley N, Yong V-W, et al: Differential role for protein kinase C-mediated signaling in the proliferation of medulloblastoma cell lines. Int. J Oncol 1998;12:759-768.
    • (1998) Int. J Oncol , vol.12 , pp. 759-768
    • Adesina, A.M.1    Dooley, N.2    Yong, V.-W.3
  • 52
    • 0025356255 scopus 로고
    • Eldar H, Zisman Y, Ullrich A, et al: Overexpression of protein kinase C a subtype in Swiss/3T3 fibroblasts causes loss of both high and low affinity receptor numbers for epidermal growth factor. J Biol Chem 1990;265:13290-13296.
    • (1990) J Biol Chem , vol.265 , pp. 13290-13296
    • Eldar, H.1    Zisman, Y.2    Ullrich, A.3
  • 53
    • 0032518455 scopus 로고    scopus 로고
    • Control of dorsoventral patterning by wnt-1 and beta-catenin
    • Capdevila J, Tabin C, Johnson RL: Control of dorsoventral patterning by wnt-1 and beta-catenin. Dev Biol 1998;193:182-194.
    • (1998) Dev Biol , vol.193 , pp. 182-194
    • Capdevila, J.1    Tabin, C.2    Johnson, R.L.3
  • 54
    • 0032483375 scopus 로고    scopus 로고
    • How a growth control path takes a wrong turn to cancer
    • Pennisi E: How a growth control path takes a wrong turn to cancer. Science 1998;281:1438-1441.
    • (1998) Science , vol.281 , pp. 1438-1441
    • Pennisi, E.1
  • 55
    • 0032562603 scopus 로고    scopus 로고
    • Functional interaction of an axin homolog, conductin, with beta catenin, APC, and GSK3beta
    • Behrens J, Jerchow BA, Wurtele M, et al: Functional interaction of an axin homolog, conductin, with beta catenin, APC, and GSK3beta. Science 1998;280:596-599.
    • (1998) Science , vol.280 , pp. 596-599
    • Behrens, J.1    Jerchow, B.A.2    Wurtele, M.3
  • 56
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-myc as a target of the APC pathway
    • He T-C, Sparks AB, Rago C, et al: Identification of c-myc as a target of the APC pathway. Science 1998;281:1509-1512.
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.-C.1    Sparks, A.B.2    Rago, C.3
  • 57
    • 0032030894 scopus 로고    scopus 로고
    • Sporadic medulloblastomas contain oncogenic beta-catenin mutations
    • Zurawel RH, Chiappa SA, Allen C, et al: Sporadic medulloblastomas contain oncogenic beta-catenin mutations. Cancer Res 1998;58: 896-899.
    • (1998) Cancer Res , vol.58 , pp. 896-899
    • Zurawel, R.H.1    Chiappa, S.A.2    Allen, C.3
  • 58
    • 0030065422 scopus 로고    scopus 로고
    • Transcriptional activation of the cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
    • Liu M, Lee M-H, Cohen M, et al: Transcriptional activation of the cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev 1996;10: 142-153.
    • (1996) Genes Dev , vol.10 , pp. 142-153
    • Liu, M.1    Lee, M.-H.2    Cohen, M.3
  • 59
    • 0028986639 scopus 로고
    • p53 independent expression of p21/cip1 in muscle and other terminally differentiating cells
    • Parker SB, Eichele G, Zhang P, et al: p53 independent expression of p21/cip1 in muscle and other terminally differentiating cells. Science 1995;267:1024-1027.
    • (1995) Science , vol.267 , pp. 1024-1027
    • Parker, S.B.1    Eichele, G.2    Zhang, P.3
  • 60
    • 0030587392 scopus 로고    scopus 로고
    • Gartel AL, Serfas MS, Gartel M, et al: p21 (waf1/cip1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line. Exp Cell Res 1996;227:171-181.
    • (1996) Exp Cell Res , vol.227 , pp. 171-181
    • Gartel, A.L.1    Serfas, M.S.2    Gartel, M.3
  • 61
    • 0029791681 scopus 로고
    • waf1/cip1 expression in normal mucosa and in adenoma and adenocarcinoma of the colon: Its relationship with differentiation
    • waf1/cip1 expression in normal mucosa and in adenoma and adenocarcinoma of the colon: Its relationship with differentiation. J Pathol 1993;179:248-253.
    • (1993) J Pathol , vol.179 , pp. 248-253
    • Doglioni, C.1    Plosio, P.2    Laurino, L.3
  • 62
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ: Cancer cell cycles. Science 1996;274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 63
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • El-Deiry WS, Tokino T, Velculescu VE, et al: WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 65
    • 0029981438 scopus 로고    scopus 로고
    • The brain specific activator p35 allows cdk5 to escape inhibition by p27kipl in neurons
    • Lee MH, Nikolic M, Baptista CA, et al: The brain specific activator p35 allows cdk5 to escape inhibition by p27kipl in neurons. Proc Natl Acad Sci USA 1996;93:3259-3263.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3259-3263
    • Lee, M.H.1    Nikolic, M.2    Baptista, C.A.3
  • 66
    • 0028986932 scopus 로고
    • p27kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
    • Ponce-Castaneda MV, Lee MH, Latres E, et al: p27kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res 1995;55:1211-1214.
    • (1995) Cancer Res , vol.55 , pp. 1211-1214
    • Ponce-Castaneda, M.V.1    Lee, M.H.2    Latres, E.3
  • 67
    • 0030002553 scopus 로고    scopus 로고
    • p27/kip1 mutation found in breast cancer
    • Spirin KS, Simpso JF, Takeuchi S, et al: p27/kip1 mutation found in breast cancer. Cancer Res 1996;56:2400-2404.
    • (1996) Cancer Res , vol.56 , pp. 2400-2404
    • Spirin, K.S.1    Simpso, J.F.2    Takeuchi, S.3
  • 68
    • 0029878892 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p57KIP2 in soft tissue sarcomas and Wilms' tumors
    • Orlow I, lavarone A, Crider-Milner SJ, et al: Cyclin-dependent kinase inhibitor p57KIP2 in soft tissue sarcomas and Wilms' tumors. Cancer Res 1996;56:1219-1221.
    • (1996) Cancer Res , vol.56 , pp. 1219-1221
    • Orlow, I.1    Lavarone, A.2    Crider-Milner, S.J.3
  • 69
    • 0029005262 scopus 로고
    • Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer
    • Mousses S, Ozcelik H, Lee PD, et al: Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer. Hum Mol Genet 1995;4:1089-1092.
    • (1995) Hum Mol Genet , vol.4 , pp. 1089-1092
    • Mousses, S.1    Ozcelik, H.2    Lee, P.D.3
  • 70
    • 0024591896 scopus 로고
    • Phenotypic analysis of four human medulloblastoma cell lines and transplantable xenografts
    • He X, Med MS, Skapek SX, et al: Phenotypic analysis of four human medulloblastoma cell lines and transplantable xenografts. J Neuropathol Exp Neurol 1989;48:48-68.
    • (1989) J Neuropathol Exp Neurol , vol.48 , pp. 48-68
    • He, X.1    Med, M.S.2    Skapek, S.X.3
  • 71
    • 0345045465 scopus 로고    scopus 로고
    • The pattern of p27kip1 expression shows a correlation between focal inhibition of proliferation and differentiation in medulloblastoma
    • Adesina AM, Dunn T, Nalbantoglu J: The pattern of p27kip1 expression shows a correlation between focal inhibition of proliferation and differentiation in medulloblastoma, abstract. J Neuropathol Exp Neurol 1998;57:521.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 521
    • Adesina, A.M.1    Dunn, T.2    Nalbantoglu, J.3
  • 72
    • 15844384256 scopus 로고    scopus 로고
    • A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis and female sterility in p27(kip1)-deficient mice
    • Fer ML, Rivkin M, Tasch M, et al: A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis and female sterility in p27(kip1)-deficient mice. Cell 1996;85:733-744.
    • (1996) Cell , vol.85 , pp. 733-744
    • Fer, M.L.1    Rivkin, M.2    Tasch, M.3
  • 73
    • 0031039957 scopus 로고
    • p16 deletion and mutation analysis in human brain tumors
    • Barker FG, Chen P, Furman F, et al: p16 deletion and mutation analysis in human brain tumors. J Neurooncol 1974;31:17-23.
    • (1974) J Neurooncol , vol.31 , pp. 17-23
    • Barker, F.G.1    Chen, P.2    Furman, F.3
  • 74
    • 0027180873 scopus 로고
    • Expression of a chain of platelet, derived growth factor and proliferative activity of human brain tumors
    • Nakamura T, Takeshita I, Inamure T, et al: Expression of a chain of platelet, derived growth factor and proliferative activity of human brain tumors. Neurol Med Chir (Tokyo) 1993;33:205-211.
    • (1993) Neurol Med Chir (Tokyo) , vol.33 , pp. 205-211
    • Nakamura, T.1    Takeshita, I.2    Inamure, T.3
  • 75
    • 0028176770 scopus 로고
    • TGB beta 1 and TGF beta 2 are potential growth regulators for medulloblastomas, primitive neuroectodermal tumors and ependymomas: Evidence in support of an autocrine hypothesis
    • Jennings MT, Kaariainen IT, Gold L, et al: TGB beta 1 and TGF beta 2 are potential growth regulators for medulloblastomas, primitive neuroectodermal tumors and ependymomas: Evidence in support of an autocrine hypothesis. Hum Pathol 1994;25:464-475.
    • (1994) Hum Pathol , vol.25 , pp. 464-475
    • Jennings, M.T.1    Kaariainen, I.T.2    Gold, L.3
  • 76
    • 0029102254 scopus 로고
    • Inhibition of proliferation and induction of differentiation in medulloblastoma and astrocytoma derived cell lines with phenylacetate
    • Stockhammer G, Manley GT, Johnson R, et al: Inhibition of proliferation and induction of differentiation in medulloblastoma and astrocytoma derived cell lines with phenylacetate. J Neurosurgery 1995;83:672-681.
    • (1995) J Neurosurgery , vol.83 , pp. 672-681
    • Stockhammer, G.1    Manley, G.T.2    Johnson, R.3
  • 77
    • 0028878530 scopus 로고
    • Staging, scoring and grading of medulloblastoma. A postoperative prognosis predicting system based on the cases from a single institute
    • Sure U, Berghoom WJ, Bertalanffy H, et al: Staging, scoring and grading of medulloblastoma. A postoperative prognosis predicting system based on the cases from a single institute. Acta Neurochir (Wien) 1995;132:59-65.
    • (1995) Acta Neurochir (Wien) , vol.132 , pp. 59-65
    • Sure, U.1    Berghoom, W.J.2    Bertalanffy, H.3
  • 78
    • 0030054211 scopus 로고    scopus 로고
    • Effects of medulloblastoma resection on outcome in children: A report: From the children's cancer group
    • Albright AL, Wisoff JH, Zelter PM, et al: Effects of medulloblastoma resection on outcome in children: A report: from the children's cancer group. Neurosurgery 1996;38:265-271.
    • (1996) Neurosurgery , vol.38 , pp. 265-271
    • Albright, A.L.1    Wisoff, J.H.2    Zelter, P.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.