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Volumn 35, Issue 4-5, 1999, Pages 295-307

The role of T-cells in rheumatoid arthritis and the use of immunomodulating drugs

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; CYCLOSPORIN A; IMMUNOMODULATING AGENT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; METHOTREXATE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 4; PLACEBO; RAPAMYCIN; T LYMPHOCYTE RECEPTOR; TACROLIMUS; VACCINE;

EID: 0032778830     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.1999.35.4-5.552205     Document Type: Conference Paper
Times cited : (2)

References (92)
  • 2
    • 0029915761 scopus 로고    scopus 로고
    • Successful induction of severe destructive arthritis by the transfer of in vitro-activated synovial T-cells from patients with rheumatoid arthritis in severe combined immunodeficient mice
    • Sakata, A., Sakata, K., Ping, H., Ohmura, T., Tsukano, M. Kakimoto, K. Successful induction of severe destructive arthritis by the transfer of in vitro-activated synovial T-cells from patients with rheumatoid arthritis in severe combined immunodeficient mice. Clin Exp Immunol 1996, 104: 247-54.
    • (1996) Clin Exp Immunol , vol.104 , pp. 247-254
    • Sakata, A.1    Sakata, K.2    Ping, H.3    Ohmura, T.4    Tsukano, M.5    Kakimoto, K.6
  • 3
    • 0030960192 scopus 로고    scopus 로고
    • Mechanisms of cartilage destruction and novel non-surgical therapeutic strategies to retard cartilage injury in rheumatoid arthritis
    • Häuselmann, H.J. Mechanisms of cartilage destruction and novel non-surgical therapeutic strategies to retard cartilage injury in rheumatoid arthritis. Curr Opin Rheum 1997, 9: 241-50.
    • (1997) Curr Opin Rheum , vol.9 , pp. 241-250
    • Häuselmann, H.J.1
  • 4
    • 0029943271 scopus 로고    scopus 로고
    • Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis
    • Campion, G.V., Lebsack, M.E., Lookabaugh, J., Gordon, G., Catalano, M., IL-1Ra Arthritis Study Group. Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis. Arthritis Rheum 1996, 39: 1092-101.
    • (1996) Arthritis Rheum , vol.39 , pp. 1092-1101
    • Campion, G.V.1    Lebsack, M.E.2    Lookabaugh, J.3    Gordon, G.4    Catalano, M.5
  • 5
    • 0022878834 scopus 로고
    • Inhibition by cyclosporin a of streptococcal cell wall-induced arthritis and hepatic granulomas in rats
    • Yocum, D.E., Allen, J.B., Wahl, S.M., Calandra, G.B., Wilder, R.L. Inhibition by cyclosporin A of streptococcal cell wall-induced arthritis and hepatic granulomas in rats. Arthritis Rheum 1986, 29: 262-73.
    • (1986) Arthritis Rheum , vol.29 , pp. 262-273
    • Yocum, D.E.1    Allen, J.B.2    Wahl, S.M.3    Calandra, G.B.4    Wilder, R.L.5
  • 6
    • 0026748870 scopus 로고
    • Cyclosporin A, FK-506, and rapamycin: Pharmacologic probes of lymphocyte signal transduction
    • Sigal, N.H. , Dumont, F.J. Cyclosporin A, FK-506, and rapamycin: Pharmacologic probes of lymphocyte signal transduction. Ann Rev Immunol 1992, 10: 519-60.
    • (1992) Ann Rev Immunol , vol.10 , pp. 519-560
    • Sigal, N.H.1    Dumont, F.J.2
  • 7
    • 0028852791 scopus 로고
    • Three-dimensional structure and actions of immunosuppressants and their immunophilins
    • Braun, W., Kallen, J., Mikol, V., Walkinshau, M.D., Wuthrich, K. Three-dimensional structure and actions of immunosuppressants and their immunophilins. FASEB 1995, 9: 63-72.
    • (1995) FASEB , vol.9 , pp. 63-72
    • Braun, W.1    Kallen, J.2    Mikol, V.3    Walkinshau, M.D.4    Wuthrich, K.5
  • 8
    • 0001240467 scopus 로고
    • Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription
    • Krönke, M., Leonard, W.J., Depper, J.M. et al. Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Proc Natl Acad Sci USA 1984, 81: 5214-18.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5214-5218
    • Krönke, M.1    Leonard, W.J.2    Depper, J.M.3
  • 9
    • 0026090594 scopus 로고
    • FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T-lymphocytes
    • Lin, C.S., Boltz, R.C., Siekierka, J.J., Sigal, N.H. FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T-lymphocytes. Cell Immunol 1991, 133: 269-84.
    • (1991) Cell Immunol , vol.133 , pp. 269-284
    • Lin, C.S.1    Boltz, R.C.2    Siekierka, J.J.3    Sigal, N.H.4
  • 10
    • 0025734876 scopus 로고
    • Inhibition of T- and B-lymphocyte proliferation by rapamycin
    • Kay, J.E., Kromwell, L., Doe, S.E.A. , Denyer, M. Inhibition of T- and B-lymphocyte proliferation by rapamycin. Immunology 1991, 72: 544-9.
    • (1991) Immunology , vol.72 , pp. 544-549
    • Kay, J.E.1    Kromwell, L.2    Doe, S.E.A.3    Denyer, M.4
  • 11
    • 0022621629 scopus 로고
    • Immunosuppressive effects of cyclosporin A on cloned T-cells
    • Herold, K.C., Lancki, D.W., Moldwin, R.I., Fitch, F.W. Immunosuppressive effects of cyclosporin A on cloned T-cells. J Immunol 1986, 136: 1315-21.
    • (1986) J Immunol , vol.136 , pp. 1315-1321
    • Herold, K.C.1    Lancki, D.W.2    Moldwin, R.I.3    Fitch, F.W.4
  • 12
    • 0024272439 scopus 로고
    • In situ hybridization for interleukin-2 and interleukin-2 receptor mRNA in T-cells activated in the presence or absence of cyclosporin A
    • Granelli-Piperno, A. In situ hybridization for interleukin-2 and interleukin-2 receptor mRNA in T-cells activated in the presence or absence of cyclosporin A. J Exp Med 1988, 168: 1649-58.
    • (1988) J Exp Med , vol.168 , pp. 1649-1658
    • Granelli-Piperno, A.1
  • 13
    • 0024412228 scopus 로고
    • The immunosuppressant FK-506 selectively inhibits expression of early T-cell activation genes
    • Tocci, M.J., Matkovich, D.A., Collier, K.A. et al. The immunosuppressant FK-506 selectively inhibits expression of early T-cell activation genes. J Immunol 1989, 143: 718-26.
    • (1989) J Immunol , vol.143 , pp. 718-726
    • Tocci, M.J.1    Matkovich, D.A.2    Collier, K.A.3
  • 14
    • 0025647885 scopus 로고
    • Two distinct signal transmission pathways in T-lymphocytes are inhibited by complexes formed between an immunophilin and either FK-506 or rapamycin
    • Bierer, B.E., Mattila, P.S., Standaert, R.F. et al. Two distinct signal transmission pathways in T-lymphocytes are inhibited by complexes formed between an immunophilin and either FK-506 or rapamycin. Proc Natl Acad Sci USA 1990, 87: 9231-5.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9231-9235
    • Bierer, B.E.1    Mattila, P.S.2    Standaert, R.F.3
  • 15
    • 0017362502 scopus 로고
    • Inhibition of the immune response by rapamycin, a new antifungal antibiotic
    • Martel, R.R., Klicius, J., Galet, S. Inhibition of the immune response by rapamycin, a new antifungal antibiotic. Can J Physiol Pharmacol 1977, 55: 48-51.
    • (1977) Can J Physiol Pharmacol , vol.55 , pp. 48-51
    • Martel, R.R.1    Klicius, J.2    Galet, S.3
  • 17
    • 0025022365 scopus 로고
    • The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T-cells
    • Dumont, F.J., Melino, M.R., Staruch, M.J., Koprak, S.L., Fischer, P.A., Sigal, N.H. The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T-cells. J Immunol 1990, 144: 1418-24.
    • (1990) J Immunol , vol.144 , pp. 1418-1424
    • Dumont, F.J.1    Melino, M.R.2    Staruch, M.J.3    Koprak, S.L.4    Fischer, P.A.5    Sigal, N.H.6
  • 18
    • 0026081972 scopus 로고
    • Synergistic interactions of cyclosporin and rapamycin to inhibit immune performances of normal human peripheral blood lymphocytes in vitro
    • Kahan, B.D., Gibbons, S., Tejpal, N. et al. Synergistic interactions of cyclosporin and rapamycin to inhibit immune performances of normal human peripheral blood lymphocytes in vitro. Transplantation 1991, 51: 232-9.
    • (1991) Transplantation , vol.51 , pp. 232-239
    • Kahan, B.D.1    Gibbons, S.2    Tejpal, N.3
  • 19
    • 0018648301 scopus 로고
    • Die therapie der chronischen polyarthritis mit cyclosporin A, einens neuen immun-suppressivum
    • Hermann, B., Muller, W. Die therapie der chronischen polyarthritis mit cyclosporin A, einens neuen immun-suppressivum. Akt Rheumatol 1979, 4: 173-86.
    • (1979) Akt Rheumatol , vol.4 , pp. 173-186
    • Hermann, B.1    Muller, W.2
  • 20
    • 0018321051 scopus 로고
    • Cyclosporin A for psoriasis
    • Muller, W., Hermann, B. Cyclosporin A for psoriasis. New Engl J Med 1979, 301: 555.
    • (1979) New Engl J Med , vol.301 , pp. 555
    • Muller, W.1    Hermann, B.2
  • 21
    • 0004875768 scopus 로고
    • Cyclosporin in rheumatoid arthritis: Open trials with different dosages
    • R. Schindler (Ed.). Springer: Berlin
    • Amor, B., Dougados, M. Cyclosporin in rheumatoid arthritis: Open trials with different dosages. In: Cyclosporin in Autoimmune Diseases. R. Schindler (Ed.). Springer: Berlin 1985, 283-7.
    • (1985) Cyclosporin in Autoimmune Diseases , pp. 283-287
    • Amor, B.1    Dougados, M.2
  • 22
    • 0023139796 scopus 로고
    • Cyclosporin A in rheumatoid arthritis: Preliminary clinical results of an open trial
    • Dougados, M., Amor, B. Cyclosporin A in rheumatoid arthritis: preliminary clinical results of an open trial. Arthritis Rheum 1987, 30: 83-7.
    • (1987) Arthritis Rheum , vol.30 , pp. 83-87
    • Dougados, M.1    Amor, B.2
  • 23
    • 0023139794 scopus 로고
    • Cyclosporin A treatment of refractory rheumatoid arthritis
    • Weinblatt, M.E., Coblyn, J.S., Fraser, P.A. et al. Cyclosporin A treatment of refractory rheumatoid arthritis. Arthritis Rheum 1987, 30: 11-17.
    • (1987) Arthritis Rheum , vol.30 , pp. 11-17
    • Weinblatt, M.E.1    Coblyn, J.S.2    Fraser, P.A.3
  • 24
    • 0004875769 scopus 로고
    • Long-term treatment of rheumatoid arthritis with cyclosporin (CsA)
    • Bowles, C.A. Long-term treatment of rheumatoid arthritis with cyclosporin (CsA). Arthritis Rheum 1989, 32: S61.
    • (1989) Arthritis Rheum , vol.32
    • Bowles, C.A.1
  • 25
    • 0023851696 scopus 로고
    • Low dose cyclosporin in rheumatoid arthritis: A pilot study
    • Tugwell, P., Bombardier, C., Gent, M. et al. Low dose cyclosporin in rheumatoid arthritis: A pilot study. J Rheumatol 1987, 14: 1108-14.
    • (1987) J Rheumatol , vol.14 , pp. 1108-1114
    • Tugwell, P.1    Bombardier, C.2    Gent, M.3
  • 26
    • 0024352318 scopus 로고
    • Assessment of efficacy and acceptability of low dose cyclosporin in patients with rheumatoid arthritis
    • Dougados, M., Duchesne, L., Awada, H., Amor, B. Assessment of efficacy and acceptability of low dose cyclosporin in patients with rheumatoid arthritis. Ann Rheum Dis 1989, 48: 550-6.
    • (1989) Ann Rheum Dis , vol.48 , pp. 550-556
    • Dougados, M.1    Duchesne, L.2    Awada, H.3    Amor, B.4
  • 27
    • 0022591450 scopus 로고
    • Renal histopathologic alterations in patients treated with cyclosporine for uveitis
    • Palestine, A.G., Austin, H.A., Balow, J.E. et al. Renal histopathologic alterations in patients treated with cyclosporine for uveitis. New Engl J Med 1986, 314: 1293-8.
    • (1986) New Engl J Med , vol.314 , pp. 1293-1298
    • Palestine, A.G.1    Austin, H.A.2    Balow, J.E.3
  • 28
    • 0023137311 scopus 로고
    • An open, controlled, randomized comparison of cyclosporine and azathioprine in the treatment of rheumatoid arthritis: A preliminary report
    • Førre, Ø., Bjerkhoel, F., Salvesen, C.F. et al. An open, controlled, randomized comparison of cyclosporine and azathioprine in the treatment of rheumatoid arthritis: a preliminary report. Arthritis Rheum 1987, 30: 88-92.
    • (1987) Arthritis Rheum , vol.30 , pp. 88-92
    • Førre, Ø.1    Bjerkhoel, F.2    Salvesen, C.F.3
  • 29
    • 0022473150 scopus 로고
    • Cyclosporin treatment for rheumatoid arthritis: A placebo-controlled, double-blind, multicentre study
    • Van Rijthoven, A.W.A.M., Dijkmans, B.A.C., Goei The, H.S. et al. Cyclosporin treatment for rheumatoid arthritis: A placebo-controlled, double-blind, multicentre study. Ann Rheum Dis 1986, 45: 726-31.
    • (1986) Ann Rheum Dis , vol.45 , pp. 726-731
    • Van Rijthoven, A.W.A.M.1    Dijkmans, B.A.C.2    Goei The, H.S.3
  • 30
    • 0023847966 scopus 로고
    • Cyclosporin in rheumatoid arthritis: A double-blind, placebo-controlled study in 52 patients
    • Dougados, M., Awada, H., Amor, B. Cyclosporin in rheumatoid arthritis: A double-blind, placebo-controlled study in 52 patients. Ann Rheum Dis 1988, 47: 127-33.
    • (1988) Ann Rheum Dis , vol.47 , pp. 127-133
    • Dougados, M.1    Awada, H.2    Amor, B.3
  • 31
    • 0024208892 scopus 로고
    • Cyclosporin A in severe, treatment-refractory rheumatoid arthritis: A randomized study
    • Yocum, D.E., Klippel, J.H., Wilder, R.L. et al. Cyclosporin A in severe, treatment-refractory rheumatoid arthritis: A randomized study. Ann Intern Med 1988, 109: 863-9.
    • (1988) Ann Intern Med , vol.109 , pp. 863-869
    • Yocum, D.E.1    Klippel, J.H.2    Wilder, R.L.3
  • 32
    • 0025265635 scopus 로고
    • Low dose cyclosporin versus placebo in patients with rheumatoid arthritis
    • Tugwell, P., Bombardier, C., Gent, M. et al. Low dose cyclosporin versus placebo in patients with rheumatoid arthritis. Lancet 1990, 335: 1051-5.
    • (1990) Lancet , vol.335 , pp. 1051-1055
    • Tugwell, P.1    Bombardier, C.2    Gent, M.3
  • 33
    • 0004871047 scopus 로고
    • Cyclosporin as a disease modifier in rheumatoid arthritis
    • (Paris) Abst 197
    • Førre, Ø., Norwegian Arthritis Disease Study Group. Cyclosporin as a disease modifier in rheumatoid arthritis. 2nd Cong Immunointervention in Autoimmune Dis (Paris) 1991, Abst 197.
    • (1991) 2nd Cong Immunointervention in Autoimmune Dis
    • Førre, Ø.1
  • 34
    • 0004890885 scopus 로고
    • Cyclosporin vs azathioprine in the treatment of rheumatoid arthritis: A controlled, double-blind study
    • (Paris) Abst 198
    • Schattenkirchner, M., Kruger, K. Cyclosporin vs azathioprine in the treatment of rheumatoid arthritis: A controlled, double-blind study. 2nd Cong Immunointervention in Autoimmune Dis (Paris) 1991, Abst 198.
    • (1991) 2nd Cong Immunointervention in Autoimmune Dis
    • Schattenkirchner, M.1    Kruger, K.2
  • 35
    • 0025858422 scopus 로고
    • Comparison of cyclosporin and D-penicillamine for rheumatoid arthritis: A randomized, double-blind muticenter study
    • Van Rijthoven, A.W.A.M., Dijkmans, B.A.C., Goei The, H.S. et al. Comparison of cyclosporin and D-penicillamine for rheumatoid arthritis: A randomized, double-blind muticenter study. J Rheumatol 1991, 18: 815-20.
    • (1991) J Rheumatol , vol.18 , pp. 815-820
    • Van Rijthoven, A.W.A.M.1    Dijkmans, B.A.C.2    Goei The, H.S.3
  • 36
    • 0027412383 scopus 로고
    • An international consensus report: The use of cyclosporin A in rheumatoid arthritis
    • Panayi, G.S., Tugwell, P. An international consensus report: The use of cyclosporin A in rheumatoid arthritis. Br J Rheum 1993, 32 (Suppl. 1): 1-3.
    • (1993) Br J Rheum , vol.32 , Issue.SUPPL. 1 , pp. 1-3
    • Panayi, G.S.1    Tugwell, P.2
  • 37
    • 0026352586 scopus 로고
    • A study of the long-term efficacy and toxicity of cyclosporine A in rheumatoid arthritis
    • Madhok, R., Torley, H.I., Capell, H.A. A study of the long-term efficacy and toxicity of cyclosporine A in rheumatoid arthritis. J Rheumatol 1991, 18: 1485-9.
    • (1991) J Rheumatol , vol.18 , pp. 1485-1489
    • Madhok, R.1    Torley, H.I.2    Capell, H.A.3
  • 38
    • 0027987025 scopus 로고
    • Radiologic evidence of disease modification in rheumatoid arthritis patients treated with cyclosporine: Results of a 48-week multicenter study comparing low-dose cyclosporine with placebo
    • Førre, Ø., Norwegian Arthritis Study Group. Radiologic evidence of disease modification in rheumatoid arthritis patients treated with cyclosporine: Results of a 48-week multicenter study comparing low-dose cyclosporine with placebo. Arthritis Rheum 1994, 37: 1506-12.
    • (1994) Arthritis Rheum , vol.37 , pp. 1506-1512
    • Førre, Ø.1
  • 39
    • 23444449002 scopus 로고
    • A randomized, double-blind, 24-week controlled study of low-dose cyclosporine versus chloroquine for early rheumatoid arthritis
    • Landewé, R.B.M., Goei The, H.S., Van Rijthoven, A.W.AM., Breedveld, F.C., Dijkmans, A.C. A randomized, double-blind, 24-week controlled study of low-dose cyclosporine versus chloroquine for early rheumatoid arthritis. Arthritis Rheum 1994, 37: 637-43.
    • (1994) Arthritis Rheum , vol.37 , pp. 637-643
    • Landewé, R.B.M.1    Goei The, H.S.2    Van Rijthoven, A.W.A.M.3    Breedveld, F.C.4    Dijkmans, A.C.5
  • 41
    • 8944256867 scopus 로고    scopus 로고
    • Slow progression of joint damage in early rheumatoid arthritis treated with cyclosporin A
    • Paero, G., Priolo, F., Marubini, E. et al. Slow progression of joint damage in early rheumatoid arthritis treated with cyclosporin A. Arthritis Rheum 1996, 39: 1006-15.
    • (1996) Arthritis Rheum , vol.39 , pp. 1006-1015
    • Paero, G.1    Priolo, F.2    Marubini, E.3
  • 42
    • 33744699097 scopus 로고    scopus 로고
    • Retardation of radiologic progression in early rheumatoid arthritis patients treated with cyclosporine A: A 36-month prospective study
    • Drosos, A.A., Voulgari, P.V., Georgiou, P.E., Zikou, A.K. Retardation of radiologic progression in early rheumatoid arthritis patients treated with cyclosporine A: A 36-month prospective study. Arthritis Rheum 1997, 40 (Suppl.): S54.
    • (1997) Arthritis Rheum , vol.40 , Issue.SUPPL.
    • Drosos, A.A.1    Voulgari, P.V.2    Georgiou, P.E.3    Zikou, A.K.4
  • 43
    • 0027417963 scopus 로고
    • The immunopathogenesis of rheumatoid arthritis
    • Panayi, G.S. The immunopathogenesis of rheumatoid arthritis. Br J Rheum 1993, 32 (Suppl. 1): 4-14.
    • (1993) Br J Rheum , vol.32 , Issue.SUPPL. 1 , pp. 4-14
    • Panayi, G.S.1
  • 44
    • 84878688356 scopus 로고
    • Immunoelectron microscopic study of distribution of T-cell subsets and HLA-DR expressing cells in rheumatoid synovium
    • Kurosaka, M., Ziff, M. Immunoelectron microscopic study of distribution of T-cell subsets and HLA-DR expressing cells in rheumatoid synovium. Arthritis Rheum 1983, 26: S53.
    • (1983) Arthritis Rheum , vol.26
    • Kurosaka, M.1    Ziff, M.2
  • 45
    • 0021257742 scopus 로고
    • Immune function in severe, active rheumatoid arthritis: A relationship between peripheral blood mononuclear cell proliferation to soluble antigens and mononuclear cell subset profiles
    • Haraoui, B., Wilder, R.L., Malone, D.G., Allen, J.B., Katona, I.M., Wahl, S.M. Immune function in severe, active rheumatoid arthritis: A relationship between peripheral blood mononuclear cell proliferation to soluble antigens and mononuclear cell subset profiles. J Immunol 1984, 133: 697-701.
    • (1984) J Immunol , vol.133 , pp. 697-701
    • Haraoui, B.1    Wilder, R.L.2    Malone, D.G.3    Allen, J.B.4    Katona, I.M.5    Wahl, S.M.6
  • 46
    • 0021691606 scopus 로고
    • Immune function in severe, active rheumatoid arthritis: A relationship between peripheral blood mononuclear cell proliferation to soluble antigens and synovial tissue immunohistologic characteristics
    • Malone, D.G., Wahl, S.M., Tsokos, M., Cattel, H., Decker, J.L., Wilder, R.L. Immune function in severe, active rheumatoid arthritis: A relationship between peripheral blood mononuclear cell proliferation to soluble antigens and synovial tissue immunohistologic characteristics. J Clin Invest 1984, 74: 1173-85.
    • (1984) J Clin Invest , vol.74 , pp. 1173-1185
    • Malone, D.G.1    Wahl, S.M.2    Tsokos, M.3    Cattel, H.4    Decker, J.L.5    Wilder, R.L.6
  • 47
    • 0022571745 scopus 로고
    • Treatment of intractable rheumatoid arthritis with combined cyclophosphamide, azathioprine and hydroxychloroquine: A follow-up study
    • Csuka, M., Carreara, G.F., McCarty, D.J. Treatment of intractable rheumatoid arthritis with combined cyclophosphamide, azathioprine and hydroxychloroquine: A follow-up study. JAMA 1986, 255: 2315-19.
    • (1986) JAMA , vol.255 , pp. 2315-2319
    • Csuka, M.1    Carreara, G.F.2    McCarty, D.J.3
  • 48
    • 0019859803 scopus 로고
    • Follow-up study of patients with rheumatoid arthritis over a period of more than 10 years (1966-1978): Analysis of disease progression and treatment in 100 cases
    • Amor, B., Herson, D., Cherot, A. et al. Follow-up study of patients with rheumatoid arthritis over a period of more than 10 years (1966-1978): Analysis of disease progression and treatment in 100 cases. Ann Med Intern 1981, 132: 168-73.
    • (1981) Ann Med Intern , vol.132 , pp. 168-173
    • Amor, B.1    Herson, D.2    Cherot, A.3
  • 49
    • 0024554111 scopus 로고
    • The effects of methotrexate on the production and activity of interleukin-1
    • Segal, R., Mozes, E., Yaron, M., et al. The effects of methotrexate on the production and activity of interleukin-1. Arthritis Rheum 1989, 32: 370-7.
    • (1989) Arthritis Rheum , vol.32 , pp. 370-377
    • Segal, R.1    Mozes, E.2    Yaron, M.3
  • 50
    • 0026058617 scopus 로고
    • Suppression of collagen-induced arthritis by combination cyclosporin A and methotrexate therapy
    • Brahn, E., Peacock, D.J., Banquerigo, M.L. Suppression of collagen-induced arthritis by combination cyclosporin A and methotrexate therapy. Arthritis Rheum 1991, 34: 1282-8.
    • (1991) Arthritis Rheum , vol.34 , pp. 1282-1288
    • Brahn, E.1    Peacock, D.J.2    Banquerigo, M.L.3
  • 51
    • 0029022389 scopus 로고
    • A multi-centre, double-blind, randomized trial of low-dose cyclosporin and placebo therapy in combination with methotrexate in patients with severe rheumatoid arthritis
    • Tugwell, P., Pincus, T., Yocum, D., et al. A multi-centre, double-blind, randomized trial of low-dose cyclosporin and placebo therapy in combination with methotrexate in patients with severe rheumatoid arthritis. New Engl J Med 1995, 333: 137-41.
    • (1995) New Engl J Med , vol.333 , pp. 137-141
    • Tugwell, P.1    Pincus, T.2    Yocum, D.3
  • 52
    • 0344919838 scopus 로고
    • Combination therapy with cyclosporine and methotrexate: Results of a 24-week extension study subsequent to a 24-week double-blind study
    • Stein, C.M., Pincus, T., Brooks, R.H. et al. Combination therapy with cyclosporine and methotrexate: Results of a 24-week extension study subsequent to a 24-week double-blind study. Arthritis Rheum 1994, 37: S252.
    • (1994) Arthritis Rheum , vol.37
    • Stein, C.M.1    Pincus, T.2    Brooks, R.H.3
  • 53
    • 0007501369 scopus 로고    scopus 로고
    • Analysis of remission and full responses in rheumatoid arthritis patients treated with combination therapy for three years
    • Ferraccioli, G.F., Di Poi, E., Damato, R., Casatta, L., De Vita, S., Bartoli, E. Analysis of remission and full responses in rheumatoid arthritis patients treated with combination therapy for three years. Arthritis Rheum 1997, 40 (Suppl.): S219.
    • (1997) Arthritis Rheum , vol.40 , Issue.SUPPL.
    • Ferraccioli, G.F.1    Di Poi, E.2    Damato, R.3    Casatta, L.4    De Vita, S.5    Bartoli, E.6
  • 54
    • 0344488712 scopus 로고
    • Cyclosporine and chloroquine synergistically inhibit the interferon-γ production by CD4-positive and CDS-positive synovial T-cell clones derived from a patient with rheumatoid arthritis
    • Landewé, R.B.M., Miltenburg, A.M.M., Breedveld, F.C., Daha, M.R., Dijkmans, B.A.C. Cyclosporine and chloroquine synergistically inhibit the Interferon-γ production by CD4-positive and CDS-positive synovial T-cell clones derived from a patient with rheumatoid arthritis. Cyclosporine in RA 1964, 111-23.
    • (1964) Cyclosporine in RA , pp. 111-123
    • Landewé, R.B.M.1    Miltenburg, A.M.M.2    Breedveld, F.C.3    Daha, M.R.4    Dijkmans, B.A.C.5
  • 55
    • 0344057481 scopus 로고
    • Cyclosporine and chloroquine synergistically inhibit T-cell proliferation by interference with IL-2 production and IL-2 responsiveness
    • Landewé, R.B.M., Miltenburg, A.M.M., Verdonk, M.J.A., et al. Cyclosporine and chloroquine synergistically inhibit T-cell proliferation by interference with IL-2 production and IL-2 responsiveness. Cyclosporine in RA 1964, 125-46.
    • (1964) Cyclosporine in RA , pp. 125-146
    • Landewé, R.B.M.1    Miltenburg, A.M.M.2    Verdonk, M.J.A.3
  • 56
    • 0029864699 scopus 로고    scopus 로고
    • Chloroquine combined with cyclosporine in rheumatoid arthritis: More than addition of 2 drugs alone
    • Dijkmans, B.A.C. et al. Chloroquine combined with cyclosporine in rheumatoid arthritis: more than addition of 2 drugs alone. J Rheumatol 1996, 23: 61-4.
    • (1996) J Rheumatol , vol.23 , pp. 61-64
    • Dijkmans, B.A.C.1
  • 57
    • 0030065046 scopus 로고    scopus 로고
    • Combination therapy of cyclosporine A with methotrexate or hydroxychloroquine in refractory rheumatoid arthritis
    • Salaffi, F., Carotti, M. Cervini, C. Combination therapy of cyclosporine A with methotrexate or hydroxychloroquine in refractory rheumatoid arthritis. Scand J Rheumatol 1996, 25: 16-23.
    • (1996) Scand J Rheumatol , vol.25 , pp. 16-23
    • Salaffi, F.1    Carotti, M.2    Cervini, C.3
  • 58
    • 0028149114 scopus 로고
    • Combination therapy of cyclosporin with methotrexate and gold in rheumatoid arthritis (2 pilot studies)
    • Bensen, W., Tugwell, P., Roberts, R. et al. Combination therapy of cyclosporin with methotrexate and gold in rheumatoid arthritis (2 pilot studies). J Rheum 1994, 21: 2034-8.
    • (1994) J Rheum , vol.21 , pp. 2034-2038
    • Bensen, W.1    Tugwell, P.2    Roberts, R.3
  • 59
    • 0027566194 scopus 로고
    • Immunological actions of cyclosporin A in rheumatoid arthritis
    • Yocum, D. Immunological actions of cyclosporin A in rheumatoid arthritis. Br J Rheum 1993, 32 (Suppl. 1): 38-41.
    • (1993) Br J Rheum , vol.32 , Issue.SUPPL. 1 , pp. 38-41
    • Yocum, D.1
  • 60
    • 0025006077 scopus 로고
    • Immunological parameters of response in patients with rheumatoid arthritis treated with cyclosporin A
    • Yocum, D.E., Wilder, R.L., Dougherty, S. et al. Immunological parameters of response in patients with rheumatoid arthritis treated with cyclosporin A. Arthritis Rheum 1990, 33: 1310-16.
    • (1990) Arthritis Rheum , vol.33 , pp. 1310-1316
    • Yocum, D.E.1    Wilder, R.L.2    Dougherty, S.3
  • 61
    • 84878744378 scopus 로고
    • Immunologic profile of rheumatoid arthritis patients treated with cyclosporin A and methotrexate: Results from a double-blind placebo-controlled trial
    • Walsh, B.T., Seaver, N., Bennett, R. et al. Immunologic profile of rheumatoid arthritis patients treated with cyclosporin A and methotrexate: Results from a double-blind placebo-controlled trial. Arthritis Rheum 1992, 35: S216.
    • (1992) Arthritis Rheum , vol.35
    • Walsh, B.T.1    Seaver, N.2    Bennett, R.3
  • 62
    • 4243397830 scopus 로고
    • Effects of methotrexate and methotrexate plus cyclosporine on mononuclear cell proliferation and lymphocyte surface markers in rheumatoid arthritis patients: Results of a double-blind trial
    • Yocum, D.E., Cornett, M., Olson, S., Nordensson, K. Effects of methotrexate and methotrexate plus cyclosporine on mononuclear cell proliferation and lymphocyte surface markers in rheumatoid arthritis patients: Results of a double-blind trial. Arthritis Rheum 1994, 37: S52.
    • (1994) Arthritis Rheum , vol.37
    • Yocum, D.E.1    Cornett, M.2    Olson, S.3    Nordensson, K.4
  • 63
    • 0025286343 scopus 로고
    • Kidney transplantation under FK 506
    • Starzl, T.E., Fung, J., Jordan, M., et al. Kidney transplantation under FK 506. JAMA 1990, 264: 63-7.
    • (1990) JAMA , vol.264 , pp. 63-67
    • Starzl, T.E.1    Fung, J.2    Jordan, M.3
  • 64
    • 0025773907 scopus 로고
    • Comparative studies of the effects of FK 506 and cyclosporin A on passively transferred collagen-induced arthritis in rats
    • Miyahara, H., Hotokebachi, T., Arita, C. et al. Comparative studies of the effects of FK 506 and cyclosporin A on passively transferred collagen-induced arthritis in rats. Clin Immunol Immunopathol 1991, 60: 278-88.
    • (1991) Clin Immunol Immunopathol , vol.60 , pp. 278-288
    • Miyahara, H.1    Hotokebachi, T.2    Arita, C.3
  • 65
    • 0025241710 scopus 로고
    • Inhibition by FK-506 of established lesions of collagen-induced arthritis in rats
    • Arita, C., Hotokebuchi, T., Miyahara, H. et al. Inhibition by FK-506 of established lesions of collagen-induced arthritis in rats. Clin Exp Immunol 1990, 82: 456-61.
    • (1990) Clin Exp Immunol , vol.82 , pp. 456-461
    • Arita, C.1    Hotokebuchi, T.2    Miyahara, H.3
  • 67
    • 0026034886 scopus 로고
    • Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: Role of deoxyguanosine nucleotide depletion
    • Euqui, E.M., Almquist, S.J., Muller, C.D., Allison, A.C. Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: Role of deoxyguanosine nucleotide depletion. Scand J Immunol 1991, 33: 1616-173.
    • (1991) Scand J Immunol , vol.33 , pp. 1616-2173
    • Euqui, E.M.1    Almquist, S.J.2    Muller, C.D.3    Allison, A.C.4
  • 68
    • 0025981270 scopus 로고
    • Rs-61443 - A new, potent immunosuppressive agent
    • Platz, K.P., Sollinger, H.W., Hulleh, D.A. et al. Rs-61443 - A new, potent immunosuppressive agent. Transplantation 1991, 51: 27-31.
    • (1991) Transplantation , vol.51 , pp. 27-31
    • Platz, K.P.1    Sollinger, H.W.2    Hulleh, D.A.3
  • 69
    • 0002422233 scopus 로고
    • New DMARD, mycophenolate mofetil, effectively treats refractory rheumatoid arthritis patients for one year
    • Schiff, M.H., Goldblum, R., Rees, M.M.C. New DMARD, mycophenolate mofetil, effectively treats refractory rheumatoid arthritis patients for one year. Arthritis Rheum 1991, 34(Suppl.): S89.
    • (1991) Arthritis Rheum , vol.34 , Issue.SUPPL.
    • Schiff, M.H.1    Goldblum, R.2    Rees, M.M.C.3
  • 70
    • 0008927161 scopus 로고
    • Immunologic changes in patients with rheumatoid arthritis treated for one year with a new DMARD, mycophenolate mofetil
    • Goldblum, R., Rees, M.M.C., Eaqui, E., Schiff, M.H. Immunologic changes in patients with rheumatoid arthritis treated for one year with a new DMARD, mycophenolate mofetil. Arthritis Rheum 1991, 34 (Suppl.): S157.
    • (1991) Arthritis Rheum , vol.34 , Issue.SUPPL.
    • Goldblum, R.1    Rees, M.M.C.2    Eaqui, E.3    Schiff, M.H.4
  • 71
    • 0345351081 scopus 로고    scopus 로고
    • Cellcept® (mycophenolate mofetil-MMF), a new treatment for RA: A 9-month, randomized, double-blind trial comparing 1g bid and 2g bid
    • Schiff, M., Stein, G., Leishman, B. Cellcept® (mycophenolate mofetil-MMF), a new treatment for RA: A 9-month, randomized, double-blind trial comparing 1g bid and 2g bid. Arthritis Rheum 1997, 40 (Suppl.): S194.
    • (1997) Arthritis Rheum , vol.40 , Issue.SUPPL.
    • Schiff, M.1    Stein, G.2    Leishman, B.3
  • 72
    • 0027299097 scopus 로고
    • Effects of administration of an anti-CD5 plus immunoconjugate in rheumatoid arthritis: Results of two phase II studies
    • Strand, V., Lipsky, P., Cannon, G. et al. Effects of administration of an anti-CD5 plus immunoconjugate in rheumatoid arthritis: Results of two phase II studies. Arthritis Rheum 1993, 36: 620-30.
    • (1993) Arthritis Rheum , vol.36 , pp. 620-630
    • Strand, V.1    Lipsky, P.2    Cannon, G.3
  • 73
    • 0027093377 scopus 로고
    • Treatment of rheumatoid arthritis with anti-CD4 monoclonal antibody: Open study of 25 patients with the B-F5 clone
    • Wendung, D., Racadot, E., Morel-Fourrier, B., Wijdenes, J. Treatment of rheumatoid arthritis with anti-CD4 monoclonal antibody: Open study of 25 patients with the B-F5 clone. Clin Rheumatol 1992, 11: 542-7.
    • (1992) Clin Rheumatol , vol.11 , pp. 542-547
    • Wendung, D.1    Racadot, E.2    Morel-Fourrier, B.3    Wijdenes, J.4
  • 74
    • 0025980476 scopus 로고
    • Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody
    • Horneff, G., Burmeister, G.R., Emmrich, F., Kalden, J.R. Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody. Arthritis Rheum 1991, 34: 129-40.
    • (1991) Arthritis Rheum , vol.34 , pp. 129-140
    • Horneff, G.1    Burmeister, G.R.2    Emmrich, F.3    Kalden, J.R.4
  • 75
    • 0027503243 scopus 로고
    • Use of a chimeric monoclonal anti-CD4 antibody in patients with refractory rheumatoid arthritis
    • Moreland, L.W., Bucy, R.P., Tilden, A. et al. Use of a chimeric monoclonal anti-CD4 antibody in patients with refractory rheumatoid arthritis. Arthritis Rheum 1993, 36: 307-18.
    • (1993) Arthritis Rheum , vol.36 , pp. 307-318
    • Moreland, L.W.1    Bucy, R.P.2    Tilden, A.3
  • 76
    • 0026656620 scopus 로고
    • Treatment of rheumatoid arthritis with single dose or weekly pulses of chimeric anti-CD4 monoclonal antibody
    • Choy, E.H.S., Chikanza, I.C., Kingsley, G.H., Corrigal, V., Panayi, G. Treatment of rheumatoid arthritis with single dose or weekly pulses of chimeric anti-CD4 monoclonal antibody. Scand J Immunol 1992, 36: 291-8.
    • (1992) Scand J Immunol , vol.36 , pp. 291-298
    • Choy, E.H.S.1    Chikanza, I.C.2    Kingsley, G.H.3    Corrigal, V.4    Panayi, G.5
  • 78
    • 0026783632 scopus 로고
    • Humanized monoclonal therapy for rheumatoid arthritis
    • Isaacs, J.D., Watts, R.A., Hazleman, B.L. et al. Humanized monoclonal therapy for rheumatoid arthritis. Lancet 1992, 340: 748-52.
    • (1992) Lancet , vol.340 , pp. 748-752
    • Isaacs, J.D.1    Watts, R.A.2    Hazleman, B.L.3
  • 79
    • 0029143898 scopus 로고
    • Treatment of refractory rheumatoid arthritis with humanized monoclonal antibody Campath 1H administered by daily subcutaneous injection
    • Matteson, E.L., Yocum, D.E., St. Clair, E.W. et al. Treatment of refractory rheumatoid arthritis with humanized monoclonal antibody Campath 1H administered by daily subcutaneous injection. Arthritis Rheum 1995, 38: 1187-93.
    • (1995) Arthritis Rheum , vol.38 , pp. 1187-1193
    • Matteson, E.L.1    Yocum, D.E.2    St. Clair, E.W.3
  • 80
    • 14744294919 scopus 로고
    • "Primatization" of recombinant antibodies for immunotherapy of human diseases: A macaque/human chimeric antibody against human CD4
    • Newman, R., Alberts, J., Anderson, D. et al. "Primatization" of recombinant antibodies for immunotherapy of human diseases: A macaque/human chimeric antibody against human CD4. Biotechnology 1992, 10: 1455-60.
    • (1992) Biotechnology , vol.10 , pp. 1455-1460
    • Newman, R.1    Alberts, J.2    Anderson, D.3
  • 81
    • 84878689677 scopus 로고
    • Clinical and immunopharmacologic effects of primatized IDEC-CE9.1, a monoclonal anti-CD4 antibody in a phase I trial in active rheumatoid arthritis
    • Yocum, D.E., Solinger, A.M., Lipani, J., Tesser, J., Gluck, O., Cornett, M. Clinical and immunopharmacologic effects of primatized IDEC-CE9.1, a monoclonal anti-CD4 antibody in a phase I trial in active rheumatoid arthritis. Clin Res 1995, 43: 363A.
    • (1995) Clin Res , vol.43
    • Yocum, D.E.1    Solinger, A.M.2    Lipani, J.3    Tesser, J.4    Gluck, O.5    Cornett, M.6
  • 82
    • 0008200558 scopus 로고
    • Results of a multi-dose protocol 7002 using an immunomodulating non-depleting primatized anti-CD4 monoclonal antibody: Results of a multidose study
    • Kaine, J., Solinger, A., Yocum, D. et al. Results of a multi-dose protocol 7002 using an immunomodulating non-depleting primatized anti-CD4 monoclonal antibody: Results of a multidose study. Arthritis Rheum 1995, 38: S280.
    • (1995) Arthritis Rheum , vol.38
    • Kaine, J.1    Solinger, A.2    Yocum, D.3
  • 83
    • 0000772077 scopus 로고    scopus 로고
    • Results of a placebo-controlled, multi-center trial using a primatized non-depleting, anti-CD4 monoclonal antibody in the treatment of rheumatoid arthritis
    • Levy, R., Weismann, M., Wiesenhutter, C. et al. Results of a placebo-controlled, multi-center trial using a primatized non-depleting, anti-CD4 monoclonal antibody in the treatment of rheumatoid arthritis. Arthritis Rheum 1996, 39: S122.
    • (1996) Arthritis Rheum , vol.39
    • Levy, R.1    Weismann, M.2    Wiesenhutter, C.3
  • 84
    • 0000056486 scopus 로고    scopus 로고
    • T-cell hypothesis in rheumatoid arthritis (RA) tested by humanized non-depleting anti-CD4 monoclonal antibody (mAb) treatment I: Suppression of disease activity and acute phase response
    • Panayi, G.S., Choy, E.H.S., Connolly, D.J.A. et al. T-cell hypothesis in rheumatoid arthritis (RA) tested by humanized non-depleting anti-CD4 monoclonal antibody (mAb) treatment I: Suppression of disease activity and acute phase response. Arthritis Rheum 1996, 39: S244.
    • (1996) Arthritis Rheum , vol.39
    • Panayi, G.S.1    Choy, E.H.S.2    Connolly, D.J.A.3
  • 85
    • 0028862268 scopus 로고
    • Campath-1H humanized monoclonal antibody in refractory rheumatoid arthritis: An intravenous dose-escalation study
    • Weinblatt, M.E., Maddison, P.J., Bulpitt, K.S. et al. Campath-1H humanized monoclonal antibody in refractory rheumatoid arthritis: An intravenous dose-escalation study. Arthritis Rheum 1995, 38: 1589-94.
    • (1995) Arthritis Rheum , vol.38 , pp. 1589-1594
    • Weinblatt, M.E.1    Maddison, P.J.2    Bulpitt, K.S.3
  • 87
    • 0025794329 scopus 로고
    • Diversity of rheumatoid synovial tissue T-cells by T-cell receptor analysis: Oligoclonal expansion in interleukin-2 responsive cells
    • Cooper, S.M., Dier, D.L., Roessner, K.D. et al. Diversity of rheumatoid synovial tissue T-cells by T-cell receptor analysis: Oligoclonal expansion in interleukin-2 responsive cells. Arthritis Rheum 1991, 34: 537.
    • (1991) Arthritis Rheum , vol.34 , pp. 537
    • Cooper, S.M.1    Dier, D.L.2    Roessner, K.D.3
  • 88
    • 0025324361 scopus 로고
    • Clonal dominance among synovial tissue-infiltrating lymphocytes in arthritis
    • Chatila, M.K., Pandolfi, F., Stamenkovich, I. et al. Clonal dominance among synovial tissue-infiltrating lymphocytes in arthritis. Hum Immunol 1990, 28: 252.
    • (1990) Hum Immunol , vol.28 , pp. 252
    • Chatila, M.K.1    Pandolfi, F.2    Stamenkovich, I.3
  • 89
    • 0010459254 scopus 로고
    • Clonal heterogeneity of synovial fluid T-lymphocytes from patients with rheumatoid arthritis
    • Duby, A.D., Sinclair, A.K., Osborne-Lawrence, S.L. et al. Clonal heterogeneity of synovial fluid T-lymphocytes from patients with rheumatoid arthritis. Proc Natl Acad Sci USA 1989, 86: 6206.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 6206
    • Duby, A.D.1    Sinclair, A.K.2    Osborne-Lawrence, S.L.3
  • 90
    • 9344245755 scopus 로고    scopus 로고
    • Vβ T-cell receptor peptide vaccination in rheumatoid arthritis: Results of a phase I dose escalation study
    • Moreland, L.M., Heck, L.W. Jr., Koopman, W.J. et al. Vβ T-cell receptor peptide vaccination in rheumatoid arthritis: Results of a phase I dose escalation study. J Rheumatol 1996, 23: 1353-62.
    • (1996) J Rheumatol , vol.23 , pp. 1353-1362
    • Moreland, L.M.1    Heck L.W., Jr.2    Koopman, W.J.3
  • 91
    • 0024200074 scopus 로고
    • Treatment of rheumatoid arthritis by antibodies directed against class II MHC antigens
    • Sany, J. Treatment of rheumatoid arthritis by antibodies directed against class II MHC antigens. Scand J Rheumatol 1988, 76 (Suppl.): 289.
    • (1988) Scand J Rheumatol , vol.76 , Issue.SUPPL. , pp. 289
    • Sany, J.1
  • 92
    • 0009483228 scopus 로고    scopus 로고
    • Vaccination of rheumatoid arthritis (RA) patients with DR4/1-peptide
    • St. Clair, E.W., Cohen, S.B., Fleischman, R.M. et al. Vaccination of rheumatoid arthritis (RA) patients with DR4/1-peptide. Arthritis Rheum 1997, 40: S96.
    • (1997) Arthritis Rheum , vol.40
    • St. Clair, E.W.1    Cohen, S.B.2    Fleischman, R.M.3


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