Hemodynamic and biochemical effects of 100% oxygen breathing in humans

Canadian Journal of Physiology and Pharmacology

Volumn 77, Issue 2, 1999, Pages 124-130

  Milone, Stephen D ^a   Newton, Gary E ^b   Parker, John D ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Blood pressure; Free radicals; Heart rate; Nitroglycerin; Oxygen; Plethysmography

Indexed keywords

ASCORBIC ACID; FREE RADICAL; GLYCERYL TRINITRATE; NITRIC OXIDE DONOR; OXYGEN; PLACEBO; PROSTAGLANDIN F2 ALPHA DERIVATIVE;

ADULT; ARTICLE; BIOCHEMISTRY; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; FOREARM BLOOD FLOW; HEART RATE; HEMODYNAMICS; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OXYGEN BREATHING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUBLINGUAL DRUG ADMINISTRATION; VASCULAR RESISTANCE;

EID: 0032778748     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y99-010     Document Type: Article

References (50)

1. 2-sensing cells. News Physiol. Sci. 10: 211-216.
2. Alveryd, A., and Brody, S. 1948. Cardiovascular and respiratory changes in man during oxygen breathing. Acta Physiol. Scand. 15: 140-149.
3. Asmussen, E., and Nielsen, M. 1955. The cardiac output in rest and work at low and high oxygen pressures. Acta Physiol. Scand. 35: 73-83.
4. Barratt-Boyes, B., and Wood, E. 1958. Cardiac output and related measurements and pressure values in the right heart and associated vessels, together with an analysis of the hemodynamic response to the inhalation of high oxygen mixtures in healthy subjects. J. Lab. Clin. Med. 51: 72-90.
5. Benedict, F., and Higgins, H. 1911. Effects on men at rest of breathing oxygen-rich gas mixtures. Am. J. Physiol. 28: 1-28.
6. Cameron, A., Hutton, I., Kenmure, A.C.F., and Murdock, W. 1966. Haemodynamic and metabolic effects of hyperbaric oxygen in myocardial infarction. Lancet, 2: 833-837.
7. Chow, C., Thacker, R., Changchit, C., Bridges, R., Rehm, S., Humble, J., and Turbek, J. 1986. Lower levels of vitamin C and carotenes in plasma of cigarette smokers. J. Am. Coll. Nutr. 5: 305-312.
8. Crawford, P., Good, P., Gutierrez, E., Feinberg, J., Boehmer, J., Silber, D., and Sinoway, L. 1997. Effects of supplemental oxygen on forearm vasodilation in humans. J. Appl. Physiol. 82: 1601-1606.
9. Daly, W., and Bondurant, S. 1962. Effects of oxygen breathing on the heart rate, blood pressure, and cardiac index of normal men - resting, with reactive hyperemia, and after atropine. J. Clin. Invest. 41: 126-132.
10. Daniell, H., and Bagwell, E. 1968. Effects of high oxygen on coronary flow and heart force. Am. J. Physiol. 214: 1454-1459.
11. Dautrebande, L., and Haldane, J. 1921. The effects of respiration of oxygen on breathing and circulation. J. Physiol. (London), 55: 296-299.
12. Delanty, N., Reilly, M., Pratico, D., Lawson, J., McCarthy, J., Wood, A., Ohnishi, S., Fitzgerald, D., and FitzGerald, G. 1997. 8-epi-PGF2α generation during coronary reperfusion. A potential quantitative marker of oxidant stress in vivo. Circulation, 95: 2492-2499.
13. Eggers, G., Paley, H., Leonard, J., and Warren, J. 1962. Hemodynamic responses to oxygen breathing in man. J. Appl. Physiol. 17: 75-79.
14. Frei, B., Stocker, R., and Ames, B. 1988. Antioxidant defenses and lipid peroxidation in human blood plasma. Proc. Natl. Acad. Sci. U.S.A. 85: 9748-9752.
15. Frei, B., England, L., and Ames, B. 1989. Ascorbate is an outstanding antioxidant in human blood plasma. Proc. Natl. Acad. Sci. U.S.A. 86: 6377-6381.
16. Fridovich, I. 1978. The biology of oxygen radicals. Science (Washington, D.C.), 201: 875-880.
17. Ganz, W., Donoso, R., Marcus, H., and Swan, H. 1972. Coronary hemodynamics and myocardial oxygen metabolism during oxygen breathing in patients with and without coronary artery disease. Circulation, 45: 763-768.
18. Gerschman, R., Gilbert, D., Nye, S., Dwyer, P., and Fenn, W. 1954. Oxygen poisoning and X-irradiation: a mechanism in common. Science (Washington, D.C.), 119: 623-626.
19. Grim, P., Gottlieb, L., Boddie, A., and Batson, E. 1990. Hyperbaric oxygen therapy. J. Am. Med. Assoc. 263: 2216-2220.
20. Gryglewski, R., Palmer, R., and Moncada, S. 1986. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature (London), 320: 454-456.
21. Halliwell, B. 1984. Oxygen is poisonous: the nature and medical importance of oxygen radicals. Med. Lab. Sci. 41: 157-171.
22. Haque, W., Boehmer, J., Clemson, B., Leuenberger, U., Silber, D., and Sinoway, L. 1996. Hemodynamic effects of supplemental oxygen administration in congestive heart failure. J. Am. Coll. Cardiol. 27: 353-357.
23. Jamieson, D., Chance, B., Cadenas, E., and Boveris, A. 1986. The relation of free radical production to hyperoxia. Annu. Rev. Physiol. 48: 703-719.
24. Kelly, F., and Lubec, G. 1995. Hyperoxic injury of immature guinea pig lung is mediated via hydroxyl radicals. Pediatr. Res. 38: 286-291.
25. Kenmure, A., Murdock, W., Beattie, A., Marshall, J., and Cameron, A. 1968. Circulatory and metabolic effects of oxygen in myocardial infarction. Br. Med. J. 4: 360-364.
26. Kenmure, A., Murdoch, W., Hutton, I., and Camerson, A. 1972. Hemodynamic effects of oxygen at 1 and 2 atmospheric pressure in healthy subjects. J. Appl. Physiol. 32: 223-226.
27. Keys, A., Stapp, J., and Violante, A. 1943. Responses in size, output, and efficiency of the human heart to acute alteration in the composition of inspired air. Am. J. Physiol. 138: 763-771.
28. López-Barneo, J., Benot, A., and Ureña, J. 1993. Oxygen sensing and the electrophysiology of arterial chemoreceptor cells. News Physiol. Sci. 8: 191-195.
29. Lynch, S., Morrow, J., Roberts II, L., and Frei, B. 1994. Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro. J. Clin. Invest. 93: 998-1004.
30. Moore, D., Weston, A., Hughes, J., Oakley, C., and Cleland, J. 1992. Effects of increased inspired oxygen concentrations on exercise performance in chronic heart failure. Lancet, 339: 850-853.
31. Moore, K., Darley-Usmar, V., Morrow, J., and Roberts II, L. 1995. Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite. Circ. Res. 77: 335-341.
32. Morrow, J., Awad, J., Kato, T., Takahashi, K., Badr, K., Roberts II, L., and Burk, R. 1992. Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. J. Clin. Invest. 90: 2502-2507.
33. Morrow, J., Frei, B., Longmire, A., Gaziano, J., Lynch, S., Shyr, Y., Strauss, W., Oates, J., and Roberts II, L. 1995. Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. New Engl. J. Med. 332: 1198-1203.
34. Motchnik, P., Frei, B., and Ames, B. 1994. Measurement of antioxidants in human blood plasma. Methods Enzymol. 234: 269-279.
35. Münzel, T., Sayegh, H., Freeman, B., Tarpey, M., and Harrison, D. 1995. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. J. Clin. Invest. 95: 187-194.
36. Narkiewicz, K., van de Borne, P., Montano, N., Dyken, M., Phillips, B., and Somers, V. 1998. Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apnea. Circulation, 97: 943-945.
37. Narkowicz, C., Vial, J., and McCartney, P. 1993. Hyperbaric oxygen therapy increases free radical levels in the blood of humans. Free Radical Res. Commun. 19: 71-80.
38. Pace-Asciak, C. 1987. Prostaglandins and related products profiled by GC/MS with negative-ion chemical-ionization detection. Clin. Invest. Med. 10: 117-120.
39. Pelletier, O. 1970. Vitamin C status of cigarette smokers and non-smokers. Am. J. Clin. Nutr. 23: 520-524.
40. Reilly, M., Delanty, N., Lawson, J., and FitzGerald, G. 1996. Modulation of oxidant stress in vivo in chronic cigarette smokers. Circulation, 94: 19-25.
41. Rubanyi, G., and Vanhoutte, P. 1986. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am. J. Physiol. 250: H822-H827.
42. Schectman, G., Byrd, J., and Cruchow, H. 1989. The influence of smoking on vitamin C status in adults. Am. J. Public Health, 79: 158-162.
43. Stausholm, K., Kehlet, H., and Rosenberg, J. 1995. Oxygen therapy reduces postoperative tachycardia. Anaesthesia, 50: 737-739.
44. Stuart, M., Setty, Y., Walenga, R., Graeber, J., and Ganley, C. 1984. Effects of hyperoxia and hypoxia on vascular prostacyclin formation in vitro. Pediatrics, 74: 548-553.
45. Thomas, M., Malmcrona, R., and Shillingford, J. 1965. Haemodynamic effects of oxygen in patients with acute myocardial infarction. Br. Heart J. 27: 401-407.
46. Todoki, K., Okabe, E., Kiyose, T., Sekishita, T., and Ito, H. 1992. Oxygen free radical-mediated selective endothelial dysfunction in isolated coronary artery. Am. J. Physiol. 262: H806-H812.
47. van der Vliet, A., Smith, D., O'Neill, C., Kaur, H., Darley-Usmar, V., Cross, C., and Halliwell, B. 1994. Interactions of peroxynitrite with human plasma and its constituents: oxidative damage and antioxidant depletion. Biochem. J. 303: 295-301.
48. Welch, H., Bonde-Petersen, F., Graham, T., Klausen, K., and Secher, N. 1977. Effects of hyperoxia on leg blood flow and metabolism during exercise. J. Appl. Physiol. Respir. Environ. Exercise Physiol. 42: 385-390.
49. Whitehorn, W., Edelman, A., and Hitchcock, F. 1946. The cardiovascular responses to the breathing of 100 per cent oxygen at normal barometric pressure. Am. J. Physiol. 146: 61-65.
50. Zweier, J., Duke, S., Kuppusamy, P., Sylvester, J., and Gabrielson, E. 1989. Electron paramagnetic resonance evidence that cellular oxygen toxicity is caused by the generation of superoxide and hydroxyl free radicals. FEBS Lett. 252: 12-16.