Leg ulcers and hydroxyurea: Forty-one cases

Archives of Dermatology

Volumn 135, Issue 7, 1999, Pages 818-820

  Sirieix, Marie Emmanuelle ^a   Debure, C ^a   Baudot, N ^b   Dubertret, L ^b   Roux, M E ^b   Morel, P ^b   Frances, C ^c   Loubeyres, S ^d   Beylot, C ^d   Lambert, D ^e   Humbert, P ^f   Gauthier, O ^g   Dandurand, M ^h   Guillot, B ^h   Vaillant, L ⁱ   Lorette, G ⁱ   Bonnetblanc, J M ^j   Lok, C ^k   Denoeux, J P ^k  

^a HÔPITAL BROUSSAIS   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d Service de Dermatologie   (France)

^e HÔPITAL DU BOCAGE   (France)

^f HÔPITAL SAINT JACQUES   (France)

^g Hopital Robert Boulin   (France)

^h DEPARTMENT OF NEUROLOGY   (France)

ⁱ SERVICE DE DERMATOLOGIE   (France)

^j DUPUYTREN UNIVERSITY HOSPITAL   (France)

^k AMIENS UNIVERSITY HOSPITAL   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYUREA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; FEMALE; HUMAN; HUMAN TISSUE; LEG ULCER; MALE; MYELOPROLIFERATIVE DISORDER; PRIORITY JOURNAL; SEX RATIO; SKIN ATROPHY; SKIN FIBROSIS; WOUND HEALING;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; DRUG ERUPTIONS; FEMALE; HUMANS; HYDROXYUREA; LEG ULCER; MALE; RETROSPECTIVE STUDIES;

EID: 0032778663     PISSN: 0003987X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archderm.135.7.818     Document Type: Article

References (15)

1. Boyd AS, Neldner KH. Hydroxyurea therapy. J Am Acad Dermatol. 1991;25:518-524.
2. Renfro L, Kamino H, Raphael B, Moy J, Sanchez M. Ulcerative lichen planus-like dermatitis associated with hydroxyurea. J Am Acad Dermatol. 1991;24:143-145.
3. Senet P, Aractingi S, Porneuf M, Perrin P, Duterque M. Hydroxyurea-induced dermatomyositis-like eruption. Br J Dermatol. 1995;133:455-459.
4. Daoud MS, Gibson LE, Pittelkow MR. Hydroxyurea dermopathy: a unique lichenoid eruption complicating long-term therapy with hydroxyurea. J Am Acad Dermatol. 1997;36:178-182.
5. Michel JL, Perrot JL, Thomas L, et al. Complications cutanées de l'hydroxyurée: 17 cas. Ann Dermatol Venereol. 1996;123(suppl 1):127-128.
6. Sigal M, Crickx B, Blanchet P, Perron J, Simony J, Belaïch S. Lésions cutanées induites par l'utilisation au long cours de l'hydroxyurée. Ann Dermatol Venereol. 1984;111:895-900.
7. Montefusco E, Alimena G, Gastldi R, Carlesimo OA, Valesini G, Mandelli G. Unusual dermatologic toxicity of long term therapy with hydroxyurea in chronic myelogenous leukemia. Tumori. 1986;72:317-321.
8. Nguyen TV, Margolis DJ. Hydroxyurea and lower leg ulcers. Cutis. 1993;52:217-219.
9. Esteve E, Roger M, Nguyen P, Kalis B. Cas pour diagnostic. Ann Dermatol Venerol. 1996;123:271-272.
10. Best PJ, Daoud MS, Pittelkow MR, Petit RM. Hydroxyurea-induced leg ulceration in 14 patients. Ann Intern Med. 1998;128:29-32.
11. Wirth K, Schoepf E, Mertelsmann R, Lindemann A. Leg ulceration with associated thrombocytosis: healing of ulceration associated with treatment of the raised platelet count. Br J Dermatol. 1998;138:533-535.
12. Babior BM. Erythrocyte disorders: anemia related to disturbance of DNA synthesis (megaloblastic anemias). In: Williams WJ, Buetler E, Ersley AJ, Lichtman MA, eds. Hematology. 4th ed. New York, NY: McGraw-Hill Book Co; 1990:467.
13. Gilbert HS, Stump DD, Roth EF. Hydroxyurea-associated reduction of red cell deformability [abstract]. Clin Res. 1985;33:546A.
14. Engström KG, Lötvenberg E. Treatment of myeloproliferative disorders with hydroxyurea: effects on red blood cell geometry and deformability. Blood. 1998; 91:3986-3991.
15. Rodgers GP, Dover GJ, Uyesaka N, Noguchi CT, Schechter AN, Nienhuis AW. Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease. N Engl J Med. 1993;328:73-80.