Leg ulceration with associated thrombocytosis: Healing of ulceration associated with treatment of the raised platelet count

British Journal of Dermatology

Volumn 138, Issue 3, 1998, Pages 533-535

  Wirth, K ^a   Schoepf, E ^a   Mertelsmann, R ^a   Lindemann, A ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANAGRELIDE; HYDROXYUREA;

ADULT; ARTICLE; CASE REPORT; CHRONIC MYELOID LEUKEMIA; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LEG ULCER; MYELOPROLIFERATIVE DISORDER; PATHOGENESIS; PRIORITY JOURNAL; THROMBOCYTE COUNT; THROMBOCYTOSIS; ULCER HEALING;

FEMALE; HUMANS; LEG ULCER; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MIDDLE AGED; PARANEOPLASTIC SYNDROMES; PLATELET AGGREGATION INHIBITORS; QUINAZOLINES; THROMBOCYTOSIS;

EID: 0031920094     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1998.02141.x     Document Type: Article

References (7)

1. Abe Andes W, Noveck RJ, Fleming JS. Inhibition of platelet production induced by an antiplatelet drug, anagrelide, in normal volunteers. Thromb Hemost 1984; 52: 325-8.
2. Silverstein MN, Petitt RM, Solberg LA Jr et al. Anagrelide: a new drug for treating thrombocytosis. N Engl J Med 1988; 318: 1292-4.
3. Iwama H, Kawakubo K, Nehasi Y et al. A lower-leg ulcer during hydroxyurea therapy for essential thrombocythemia. Jpn J Cancer Chemother 1996; 23: 937-9.
4. Geba GP, Ptak W, Anderson GM et al. Delayed-type hypertensensitivity in mast cell-deficient mice. Dependence on platelets for expression of contact sensitivity. J Immunol 1996; 157: 557-65.
5. 1 in collagen disease patients with inflammatory skin ulcer. Int J Tissue Reac 1983; 5: 1-10.
6. Matsuda H, Ushio H, Geba GP, Askenase PW. Human platelets can initiate T cell-dependent contact sensitivity through local serotonin release mediated by IgE antibodies. J Immunol 1997; 158: 2891-7.
7. Diacovo TG, Pun KD, Warnock RA et al. Platelet-mediated lymphocyte delivery to high endothelial venules. Science 1996; 273: 252-5.