Hepatocyte nuclear factor-6: Associations between genetic variability and Type II diabetes and between genetic variability and estimates of insulin secretion

Diabetologia

Volumn 42, Issue 8, 1999, Pages 1011-1016

  Moller A M ^a   Ek, J ^a   Durviaux, S M ^c   Urhammer, S A ^a   Clausen, J O ^a   Eiberg, H ^b   Hansen, T ^a   Rousseau, G G ^c   Lemaigre, F P ^c   Pedersen, O ^a  

^a STENO DIABETES CENTER   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c DE DUVE INSTITUTE   (Belgium)

Author keywords

Hepatocyte nuclear factor 6; Insulin secretion; MODY; Mutations; Type II diabetes mellitus

Indexed keywords

C PEPTIDE; GLUCOSE; HETERODUPLEX; INSULIN; NUCLEAR FACTOR; NUCLEAR FACTOR VI; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC VARIABILITY; GLUCOSE TOLERANCE; HUMAN; INSULIN RELEASE; MAJOR CLINICAL STUDY; MALE; MATURITY ONSET DIABETES MELLITUS; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOGENESIS; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

ADULT; ALANINE; ALLELES; AMINO ACID SUBSTITUTION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 15; CLONING, MOLECULAR; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; FEMALE; GENE FREQUENCY; HEPATOCYTE NUCLEAR FACTOR 6; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; INTRONS; MALE; MIDDLE AGED; MUTATION, MISSENSE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROLINE; REGISTRIES; TRANS-ACTIVATORS; VARIATION (GENETICS);

EID: 0032776011     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051261     Document Type: Article

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