IL-3 induces apoptosis in a ras-transformed myeloid cell line

Apoptosis

Volumn 4, Issue 2, 1999, Pages 71-80

  Ahmed, N ^a   Anderson, S M ^b   Berridge, M V ^a  

^a MALAGHAN INSTITUTE OF MEDICAL RESEARCH   (New Zealand)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Abl; Apoptosis; Interleukin 3; Oncogenes; ras

Indexed keywords

CALCIUM ION; INTERLEUKIN 3; ONCOPROTEIN; PROTEIN TYROSINE KINASE; RAS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CULTURE; CALCIUM TRANSPORT; CELL TRANSFORMATION; COLONY FORMING UNIT; CONTROLLED STUDY; ENZYME ACTIVATION; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL;

ANIMALIA;

EID: 0032774806     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009686220607     Document Type: Article

References (51)

1. Arends MJ, Wyllie AH. Apoptosis: Mechanisms and roles in pathology. Int Rev Exp Path 1991; 32: 223-254.
2. Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995; 267: 1456-1462.
3. Salvesen GS, Dixit VM. Caspases: intracellular signaling by proteolysis. Cell 1997; 91: 443-446.
4. Cohen GM. Caspases: the executioners of apoptosis. Biochem J 1997; 326: 1-16.
5. Nagata S. Apoptosis by death factor. Cell 1997; 88: 355-365.
6. Cohen GM, Sun XM, Fearnhead H, et al. Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes. J Immunol 1994; 153: 507-516.
7. Enari M, Sakahira H, Yokoyama H, et al. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998; 391: 43-50.
8. Steller H. Mechanisms and genes of cellular suicide. Science 1995; 267: 1445-1449.
9. Gulbins E, Bissonnette R, Mahboubi A, et al. FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity 1995; 2: 341-351.
10. Chen CY, Liou J, Forman LW, Faller DV. Differential regulation of discrete apoptotic pathways by Ras. J Biol Chem 1998; 273: 16700-16708.
11. Chen CY, Faller DV. Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis. J Biol Chem 1996; 271: 2376-2379.
12. Arends MJ, McGregor AH, Toft NJ, Brown EJ, Wyllie AH. Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability. Brit J Cancer 1993; 68: 1127-1133.
13. Hermens AF, Bentvelzen PA. Influence of the H-ras oncogene on radiation responses of a rat rhabdomyosarcoma cell line. Cancer Res 1992; 52: 3073-3082.
14. Fernandez A, Marin MC, McDonnell T, Ananthaswamy HN. Differential sensitivity of normal and Ha-ras-transformed C3H mouse embryo fibroblasts to tumor necrosis factor: induction of bcl-2, c-myc, and manganese superoxide dismutase in resistant cells. Oncogene 1994; 9: 2009-2017.
15. Askew DS, Ashmun RA, Simmons BC, Cleveland JL. Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene 1991; 6: 1915-1922.
16. Evan GI, Wyllie AH, Gilbert CS, et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992; 69: 119-128.
17. Jacobson MD, Burne JF, Raff MC. Programmed cell death and Bcl-2 protection in the absence of a nucleus. EMBO J 1994; 13: 1899-1910.
18. Chen YY, Rosenberg N. Lymphoid cells transformed by Abelson virus require the v-abl protein-tyrosine kinase only during early G1. Proc Natl Acad Sci USA 1992; 89: 6683-6687.
19. Whyte M, Evan G. Apoptosis. The last cut is the deepest. Nature 1995; 376: 17-18.
20. Uckun FM, Tuel AL, Song CW, et al. Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death. Proc Natl Acad Sci USA 1992; 89: 9005-9009.
21. Armstrong DK, Kaufmann SH, Ottaviano YL, et al. Epidermal growth factor-mediated apoptosis of MDA-MB-468 human breast cancer cells. Cancer Res 1994; 54: 5280-5283.
22. Brabyn CJ, Franks DJ, Kleine LP. Long-term exposure to epidermal growth factor results in apoptosis in T51B cells. Biochem Cell Biol 1994; 72: 429-438.
23. Gooch JL, Lee AV, Yee D. Interleukin 4 inhibits growth and induces apoptosis in human breast cancer cells. Cancer Res 1998; 58: 4199-4205.
24. Greenberger JS, Sakakeeny MA, Humphries RK, Eaves CJ, Eckner RJ. Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic cell lines. Proc Natl Acad Sci USA 1983; 80: 2931-2935.
25. DeClue JE, Stone JC, Blanchard RA, et al. A ras effector domain mutant which is temperature sensitive for cellular transformation: interactions with GTPase-activating protein and NF-1. Mol Cell Biol 1991; 11: 3132-3138.
26. Kipreos ET, Lee GJ, Wang JY. Isolation of temperature-sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine. Proc Natl Sci USA 1987; 84: 1345-1349.
27. Cheng HC, Nishio H, Hatase O, Ralph S, Wang JH. A synthetic peptide derived from p34cdc2 is a specific and efficient substrate of src-family tyrosine kinases. J Biol Chem 1992; 267: 9248-9256.
28. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
29. Watson JD, Jenkins DR, Eszes M, Leung E. Effect of granulocyte-macrophage colony-stimulating factor and interleukin 3 on the v-src oncogene. Inhibition of tyrosine kinase activity in the absence of changes in gene expression. J Immunol 1988; 140: 501-507.
30. Watson JD, Prestidge RL, Jenkins DR. Cytokines that inhibit tyrosine kinase activity: Receptor structure and signal transduction. In: Cacciola E, Deisseroth AB, Giustolisi R, eds. Hemopoietic growth factors, oncogenes and cytokines in clinical hematology. Basel: Karger 1994: 64-78.
31. McGahon A, Bissonnette R, Schmitt M, et al. BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood 1994; 83: 1179-1187.
32. McGahon AJ, Nishioka WK, Martin SJ, et al. Regulation of the Fas apoptotic cell death pathway by Abl. J Biol Chem 1995; 270: 22625-22631.
33. Yi TL, Cleveland JL, Ihle JN. Protein tyrosinephosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13. Mol Cell Biol 1992; 12: 836-846.
34. Su X, Zhou T, Wang Z, et al. Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis. Immunity 1995; 2: 353-302.
35. Sun H, Tonks NK, Bar SD. Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science 1994; 266: 285-288.
36. Singh S, Aggarwal BB. Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B. J Biol Chem 1995; 270: 10631-10639.
37. Dobrowsky RT, Hannun YA. Ceramide stimulates a cytosolic protein phosphatase. J Biol Chem 1992; 267: 5048-5051.
38. Chin YE, Kitagawa M, Su WC, et al. Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 1996; 272: 719-722.
39. Gore SD, Donnenberg AD, Zehnbauer BA, Weng LJ, Burke PJ. Granulocyte-macrophage colony-stimulating factor (GM-CSF), given concurrently with induction therapy for acute myelogenous leukemia (AML), augments the syndrome of T-lymphocyte recovery. Leukemia 1994; 8: 409-419.
40. Ahmed N, Williams JF, Weidemann MJ. The human promyelocytic HL60 cell line: a model of myeloid cell differentiation using dimethylsulphoxide, phorbol ester and butyrate. Biochem Int 1991; 23: 591-602.
41. McConkey DJ, Fernandez A, Trent Jn, Ananthaswamy HN. Oncogene regulation of endonuclease activation in apoptosis. Cancer Lett 1995; 94: 9-16.
42. Fernandez A, Fosdick LJ, Marin MC, et al. Differential regulation of endogenous endonuclease activation in isolated murine fibroblast nuclei by ras and bcl-2. Oncogene 1995; 10: 769-774.
43. Ostad M, Shu WP, Kong L, Liu BC. Ha-ras oncogene expression abrogates a pH dependent endonuclease activity of apoptosis in normal rat kidney cells. Cancer Lett 1996; 98: 175-182.
44. Baffy G, Miyashita T, Williamson JR, Reed JC. Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. J Biol Chem 1993; 268: 6511-6519.
45. Hannun YA. Functions of cramide in coordinating cellular responses to stress. Science 1996; 274: 1855-1858.
46. Kohl NE, Mosser SD, deSolms SJ, et al. Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science 1993; 260: 1934-1937.
47. Barrington RE, Subler MA, Rands E,et al. A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Mol Cell Biol 1998; 18: 85-92.
48. Coffey MC, Strong JE, Forsyth PA, Lee PWK. Reovirus therapy of tumours with activated Ras pathway. Science 1998; 282: 1332-1334.
49. Gallagher AP, Burnett AK, Bowen DT, Darley RL. Mutant RAS selectively promotes sensitivity of myeloid leukemia cells to apoptosis by a protein kinase C-dependent process. Cancer Res 1998; 58: 2029-2035.
50. Fenton RG, Hixon JA, Wright PW, Brooks AD, Sayers TJ. Inhibition of Fas (CD95) expression and Fas-mediated apoptosis by oncogenic Ras. Cancer Res 1998; 58: 3391-3400.
51. Tang C, Huang Y, Ponnathpur VS, et al. Combined antileukemic activity of pIXY 321 and Ara-C against human acute myeloid leukemia cells. Leukemia & Lymphoma 1994; 15: 445-451.