Autoimmune ovarian inflammation triggered by proinflammatory (Th1) T cells is compatible with normal ovarian function in mice

Biology of Reproduction

Volumn 61, Issue 3, 1999, Pages 635-642

  Bagavant, Harini ^a   Adams, Sallie ^a   Terranova, Paul ^b   Chang, Alice ^a   Kraemer, Frances W ^a   Lou, Yahuan ^a   Kasai, Ken ^a   Luo, An Ming ^a   Tung, Kenneth S K ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; GAMMA INTERFERON; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ESTRUS CYCLE; FEMALE; HELPER CELL; ISOGRAFT; MOUSE; NONHUMAN; OVARY FUNCTION; OVARY INFLAMMATION; PREGNANCY RATE; PRIORITY JOURNAL; THYMECTOMY;

ANIMALS; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CYTOKINES; EGG PROTEINS; ESTRUS; FEMALE; INFERTILITY, FEMALE; INTERFERON TYPE II; INTERLEUKIN-1; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED A; MICE, INBRED C57BL; OOPHORITIS; OVARY; RECEPTORS, CELL SURFACE; RNA, MESSENGER; TH1 CELLS; THYMECTOMY; TUMOR NECROSIS FACTOR-ALPHA; ZONA PELLUCIDA;

ANIMALIA; FALLOPIA; MURINAE;

EID: 0032773747     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod61.3.635     Document Type: Article

References (42)

1. Bannatyne P, Russel P, Shearman RP. Autoimmune oophoritis: a clinicopathologic assessment of 12 cases. Int J Gynecol Pathol 1990; 9: 191-207.
2. Irvine WJ. Autoimmunity in endocrine disease. Recent Prog Horm Res 1980; 36:509-556.
3. Irvine WJ, Chan MMW, Scarth L, Kolb FO, Hartog M, Bayliss RIS, Drury MI. Immunological aspects of premature ovarian failure associated with idiopathic Addison's disease. Lancet 1968; 2:883-887.
4. Coulam CB. Premature ovarian failure - evidence for the autoimmune mechanism. Fertil Steril 1981; 36:238-240.
5. Russell P, Bannatyne P, Shearman RP, Fraser IS, Corbett P. Premature hypergonadotropic ovarian failure: clinicopathological study of 19 cases. Int J Gynecol Pathol 1982; 1:185-201.
6. McDonald AH, Swanborg RH. Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis. J Immunol 1988; 140:1132-1138.
7. Campbell IL, Kay TW, Oxbrow L, Harrison LC. Essential role for interferon gamma and interleukin 6 in autoimmune insulin dependant diabetes in NOD/Wehi mice. J Clin Invest 1991; 87:739-742.
8. Norman RJ, Brannstrom M. Cytokines in the ovary: pathophysiology and potential for pharmacological intervention. Pharmacol Ther 1996; 69:219-236.
9. Coulam CB, Stern JJ. Immunology of ovarian failure. Am J Reprod Immunol 1991; 25:169-174.
10. Paterson M, Koothan PT, Morris KD, O'Byrne KT, Braude P, Williams A, Aitken RJ. Analysis of contraceptive potential of antibodies against native and deglycosylated porcine ZP3 in vivo and in vitro. Biol Reprod 1992; 46:523-534.
11. VandeVoort CA, Schwoebel ED, Dunbar BS. Immunization of monkeys with recombinant complimentary deoxyribonucleic acid expressed zona pellucida proteins. Fertil Steril 1995; 64:838-847.
12. Kojima A, Prehn RT. Genetic susceptibility to post-thymectomy autoimmune diseases in mice. Immunogenetics 1981; 14:15-27.
13. Tung KSK, Smith S, Teuscher C, Cook C, Anderson RE. Murine autoimmune oophoritis, epididymoorchitis and gastritis induced by day 3 thymectomy. Am J Pathol 1987; 126:293-302.
14. Wardell BB, Michael SD, Tung KSK, Todd JA, Blakenhorn EP, Mcentee K, Sudweeks JD, Hansen WK, Meeker ND, Griffith JS, Livingstone KD, Teuscher C. Aodl, the immunoregulatory locus controlling abrogation of tolerance in neonatal thymectomy induced autoimmune ovarian dysgenesis, maps to mouse chromosome 16. Proc Natl Acad Sci USA 1995; 92:4758-4762.
15. Teuscher C, Wardell BB, Lunceford JK, Michael SD, Tung KSK. Aod2, the locus controlling development of atrophy in neonatal thymectomy induced autoimmune ovarian dysgenesis, co-localizes with IL-2, Fgfb and Idd3. J Exp Med 1996; 183:631-637.
16. Rhim SH, Millar SE, Robey F, Luo AM, Lou YH, Yule T, Allen P, Dean J, Tung KSK. Autoimmune disease of the ovary induced by a ZP3 peptide from the mouse zona pellucida. J Clin Invest 1992; 89: 28-35.
17. Lou YH, Ang J, Thai H, McElveen F, Tung KSK. A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology. J Immunol 1995; 155:2715-2720.
18. Rugh R. The estrous cycle. In: the mouse: its reproduction and development. Oxford, Great Britain: Oxford University Press; 1993: 38-41.
19. Reiner SL, Zheung S, Corry DB, Locksley RM. Constructing polycompetitor cDNAs for quantitative PCR. J Immunol Methods 1994; 175:275.
20. Montgomery RA, Dallman MJ. Analysis of cytokine gene expression during fetal thymic ontogeny using polymerase chain reaction. J Immunol 1991; 147:554-560.
21. Pederson T, Peters H. Proposal for classification of oocytes and follicles in the mouse ovary. J Reprod Fertil 1968; 17:555-557.
22. Byskov AGS. Cell kinetic studies of follicular atresia in the mouse ovary. J Reprod Fertil 1974; 37:277-285.
23. Lou YH, Tung KSK. T cell peptide of a self protein elicits autoantibody to the protein antigen: implications for specificity and pathogenetic role of antibody in autoimmunity. J Immunol 1993; 151:5790-5799.
24. Lou YH, McElveen MF, Garza KM, Tung KSK. Rapid induction of autoantibodies by endogenous ovarian antigens and activated T cells. J Immunol 1996; 156:3535-3540.
25. Mossman TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-2357.
26. Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway CA. Surface expression of alpha 4 integrin is required for entry into brain parenchyma. J Exp Med 1993; 177:57-68.
27. Chen HL, Marcinkiewicz JL, Sancho-Tello M, Hum JS, Terranova PF. Tumor necrosis factor a gene expression in mouse oocytes and follicular cells. Biol Reprod 1993; 48:707-714.
28. Tung KSK, Lu CY. Immunologic basis of reproductive failure. In: Kraus FT, Damjanov I, Kaufman N (eds.), Pathology of Reproductive. Baltimore, MD: Failure Williams and Wilkins; 1991: 308-333.
29. Yule TD, Tung KSK. Experimental autoimmune orchitis induced by testis and sperm antigen specific T cell clones: an important pathogenic cytokine is tumor necrosis factor. Endocrinology 1993; 133: 1098-1107.
30. Terranova PF, Rice VM. Review: cytokine involvement in ovarian processes. Am J Reprod Immunol 1997; 37:50-63.
31. Adashi EY. The potential relevance of cytokines to ovarian physiology. J Steroid Biochem 1992; 43:439-444.
32. Brannstrom M, Wang L, Norman RJ. Ovulatory effect of interleukin Iβ on the perfused rat ovary. Endocrinology 1993; 132:399-404.
33. Hakuno N, Koji T, Yano T, Kobayashi N, Tsutsumi O, Nakane PK. Fas/Apo-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia. Endocrinology 1996; 137:1938-1948.
34. Azmi TI, O'Shea JD. Mechanism of deletion of endothelial cells during regression of the corpus luteum. Lab Invest 1984; 51:206-217.
35. Sancho-Tello M, Tash JS, Roby KF, Terranova PF. Effects of lipopolysaccharide on ovarian function in the pregnant mare serum gonadotropin-treated immature rat. Endocr J 1993; 1:503-511.
36. Hill JA, Welch WR, Faris HMP, Anderson DJ. Induction of class II major histocompatibility complex antigen expression on human granulosa cells by interferon gamma: a potential mechanism contributing to autoimmune failure. Am J Obstet Gynecol 1990; 162:534-540.
37. Feldmann M, Brennan FM, Chantry D, Haworth C, Turner M, Katsikis P, Londei M, Abney E, Buchan G, Barrett K, Corcoran A, Kissonerghis M, Zheng R, Grubeck-Loebentein B, Barkley D, Chu CQ, Field M, Maini RN. Cytokine assays: role in evaluation of the pathogenesis of autoimmunity. Immunol Rev 1991; 119:105-123.
38. Kagi D, Odermatt B, Seiler P, Zinkernagel RM, Mak TW, Hengartner H. Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. J Exp Med 1997; 186:989-997.
39. Levine S, Sowinski R. Experimental allergic encephalomyelitis: inhibition of clinical signs and paradoxical enhancement of lesion in second attacks. Am J Pathol 1980; 101:375-386.
40. Gladue RP, Carroll LA, Milici AJ, Scampoli DN, Stukenbrok HA, Pettipher ER, Salter ED, Contillo SL, Showell HJ. Inhibition of leukotriene B4 receptor interaction suppresses eosinophil infiltration and disease pathology in murine model of experimental allergic encephalomyelitis. J Exp Med 1996; 183:1893-1898.
41. Agersborg SS, Garza KM, Baker D, Tung KSK. Syphacia obvelata (pinworm) infection: a potent modifier in the neonatal induction of autoimmune disease and pathogenic Th2 memory response. In: Keystone Symposium: T Lymphocyte Activation, Differentiation and Death; 1998; Keystone, CO. Abstract 4002.
42. Lou YH, Park KK, Agersborg SS, Tung KSK. Binding of autoantibody to an ovarian tissue antigen directs targeting of T cell mediated oophoritis. In: Serono Symposium: XIth Ovarian Workshop: Ovarian Cell Growth, Apoptosis and Cancer; 1996; London, Ontario, Canada. Abstract 31.