메뉴 건너뛰기




Volumn 34, Issue 2, 1999, Pages 219-228

Levosimendan enhances cardiac performance after cardiopulmonary bypass: A prospective, randomized placebo-controlled trial

Author keywords

Inotropic drags; Left ventricular function; Myofilament calcium sensitizer

Indexed keywords

CALCIUM; LEVOSIMENDAN; MIDAZOLAM; SUFENTANIL; TROPONIN C; UNCLASSIFIED DRUG; VECURONIUM;

EID: 0032771929     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199908000-00007     Document Type: Article
Times cited : (148)

References (30)
  • 1
    • 0028172183 scopus 로고
    • 2+ sensitizer, levosimendan, to recombinant human cardiac troponin C: A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study
    • 2+ sensitizer, levosimendan, to recombinant human cardiac troponin C: a molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study. J Biol Chem 1994;269:28584-90.
    • (1994) J Biol Chem , vol.269 , pp. 28584-28590
    • Pollesello, P.1    Ovaska, M.2    Kaivola, J.3
  • 2
    • 0029061923 scopus 로고
    • 2+ sensitivity of cardiac myofibrils and sarcoplasmic reticulum in guinea pig heart
    • 2+ sensitivity of cardiac myofibrils and sarcoplasmic reticulum in guinea pig heart. Circ Res 1995;77:107-13.
    • (1995) Circ Res , vol.77 , pp. 107-113
    • Edes, I.1    Kiss, E.2    Kitada, Y.3
  • 4
    • 0030955524 scopus 로고    scopus 로고
    • The role of cAMP-and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan
    • Haikala H, Kaheinen P, Levijoki J, Linden I-B. The role of cAMP-and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan. Cardiovasc Res 1997;34: 536-46.
    • (1997) Cardiovasc Res , vol.34 , pp. 536-546
    • Haikala, H.1    Kaheinen, P.2    Levijoki, J.3    Linden, I.-B.4
  • 6
    • 0029613261 scopus 로고
    • Mechanisms of action of calcium-sensitizing drugs
    • Haikala H, Linden I-B. Mechanisms of action of calcium-sensitizing drugs. J Cardiovasc Pharmacol 1995;26(suppl 1): S10-9.
    • (1995) J Cardiovasc Pharmacol , vol.26 , Issue.1 SUPPL.
    • Haikala, H.1    Linden, I.-B.2
  • 7
    • 0029097331 scopus 로고
    • Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs
    • Harkin CP, Pagel PS, Tessmer JP, Warltier DC. Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs. J Cardiovasc Pharmacol 1995;26:179-88.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 179-188
    • Harkin, C.P.1    Pagel, P.S.2    Tessmer, J.P.3    Warltier, D.C.4
  • 8
    • 0028826965 scopus 로고
    • Zatebradine, a specific bradycardic agent, alters the hemodynamic and left ventricular mechanical actions of levosimendan, a new myofilament calcium sensitizer, in conscious dogs
    • Pagel PS, Harkin CP, Hettrick DA, Warltier DC. Zatebradine, a specific bradycardic agent, alters the hemodynamic and left ventricular mechanical actions of levosimendan, a new myofilament calcium sensitizer, in conscious dogs. J Pharmacol Exp Ther 1995; 275:127-35.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 127-135
    • Pagel, P.S.1    Harkin, C.P.2    Hettrick, D.A.3    Warltier, D.C.4
  • 10
    • 0030434483 scopus 로고    scopus 로고
    • Effects of levosimendan on myocardial contractility and oxygen consumption
    • Todaka K, Wang J, Yi G-H, et al. Effects of levosimendan on myocardial contractility and oxygen consumption. J Pharmacol Exp Ther 1996;279:120-7.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 120-127
    • Todaka, K.1    Wang, J.2    Yi, G.-H.3
  • 11
    • 0030918670 scopus 로고    scopus 로고
    • Levosimendan enhances left ventricular systolic and diastolic function in conscious dogs with pacing-induced cardiomyopathy
    • Pagel PS, McGough MF, Hettrick DA, et al. Levosimendan enhances left ventricular systolic and diastolic function in conscious dogs with pacing-induced cardiomyopathy. J Cardiovasc Pharmacol 1997;29:563-73.
    • (1997) J Cardiovasc Pharmacol , vol.29 , pp. 563-573
    • Pagel, P.S.1    McGough, M.F.2    Hettrick, D.A.3
  • 14
    • 0028361208 scopus 로고
    • Hemodynamic effects of the novel cardiotonic drug simendan: Echocardiographic assessment in healthy volunteers
    • Lilleberg JM, Sundberg S, Leikola-Pelho T, Nieminen MS. Hemodynamic effects of the novel cardiotonic drug simendan: echocardiographic assessment in healthy volunteers. Cardiovasc Drugs Ther 1994;8:263-9.
    • (1994) Cardiovasc Drugs Ther , vol.8 , pp. 263-269
    • Lilleberg, J.M.1    Sundberg, S.2    Leikola-Pelho, T.3    Nieminen, M.S.4
  • 15
    • 0029038397 scopus 로고
    • Hemodynamic and neurohumoral effects of levosimendan, a new calcium sensitizer, at rest and during exercise in healthy men
    • Sundberg S, Lilleberg J, Nieminen MS, Lehtonen L. Hemodynamic and neurohumoral effects of levosimendan, a new calcium sensitizer, at rest and during exercise in healthy men. Am J Cardiol 1995;75:1061-6.
    • (1995) Am J Cardiol , vol.75 , pp. 1061-1066
    • Sundberg, S.1    Lilleberg, J.2    Nieminen, M.S.3    Lehtonen, L.4
  • 16
  • 17
    • 0029558280 scopus 로고
    • Dose-ranging study of a new calcium sensitizer, levosimendan, in patients with left ventricular dysfunction
    • Lilleberg J, Sundberg S, Nieminen MS. Dose-ranging study of a new calcium sensitizer, levosimendan, in patients with left ventricular dysfunction. J Cardiovasc Pharmacol 1995;26(suppl 1): S63-9.
    • (1995) J Cardiovasc Pharmacol , vol.26 , Issue.1 SUPPL.
    • Lilleberg, J.1    Sundberg, S.2    Nieminen, M.S.3
  • 18
    • 0029995121 scopus 로고    scopus 로고
    • Hemodynamic interactions of a new calcium sensitizing drug levosimendan and captopril
    • Antila S, Eha J, Heinpalu M, et al. Hemodynamic interactions of a new calcium sensitizing drug levosimendan and captopril. Eur J Clin Pharmacol 1996;49:451-8.
    • (1996) Eur J Clin Pharmacol , vol.49 , pp. 451-458
    • Antila, S.1    Eha, J.2    Heinpalu, M.3
  • 20
    • 0029970897 scopus 로고    scopus 로고
    • Recovery of systolic and diastolic left ventricular function early after cardiopulmonary bypass
    • De Hert SG, Rodrigus IE, Haenen LR, De Mulder PA, Gillebert TC. Recovery of systolic and diastolic left ventricular function early after cardiopulmonary bypass. Anesthesiology 1996;85: 1063-75.
    • (1996) Anesthesiology , vol.85 , pp. 1063-1075
    • De Hert, S.G.1    Rodrigus, I.E.2    Haenen, L.R.3    De Mulder, P.A.4    Gillebert, T.C.5
  • 21
    • 0027184306 scopus 로고
    • Myocardial dysfunction following cardiopulmonary bypass: Recovery patterns, predictors of inotropic need, theoretical concepts of inotropic administration
    • Royster RL. Myocardial dysfunction following cardiopulmonary bypass: recovery patterns, predictors of inotropic need, theoretical concepts of inotropic administration. J Cardiothorac Vasc Anesth 1993;7(suppl 2):19-25.
    • (1993) J Cardiothorac Vasc Anesth , vol.7 , Issue.2 SUPPL. , pp. 19-25
    • Royster, R.L.1
  • 22
    • 0027385972 scopus 로고
    • Combined inotropic effects of amrinone and epinephrine after cardiopulmonary bypass in humans
    • Royster RL, Butterworth IV JF, Prielipp RC, et al. Combined inotropic effects of amrinone and epinephrine after cardiopulmonary bypass in humans. Anesth Analg 1993;77:662-72.
    • (1993) Anesth Analg , vol.77 , pp. 662-672
    • Royster, R.L.1    Butterworth IV, J.F.2    Prielipp, R.C.3
  • 23
    • 0027290756 scopus 로고
    • Amrinone, in combination with norepinephrine, is an effective first-line drug for difficult separation from cardiopulmonary bypass
    • Hardy J-F, Searle N, Roy M, Perrault J. Amrinone, in combination with norepinephrine, is an effective first-line drug for difficult separation from cardiopulmonary bypass. Can J Anaesth 1993;40: 495-501.
    • (1993) Can J Anaesth , vol.40 , pp. 495-501
    • Hardy, J.-F.1    Searle, N.2    Roy, M.3    Perrault, J.4
  • 24
    • 0026641041 scopus 로고
    • Amrinone and dobutamine as primary treatment of low cardiac output syndrome following coronary artery surgery: A comparison of their effects on hemodynamics and outcome
    • Dupuis J-Y, Bondy R, Cattran C, Nathan HJ, Wynands JE. Amrinone and dobutamine as primary treatment of low cardiac output syndrome following coronary artery surgery: a comparison of their effects on hemodynamics and outcome. J Cardiothorac Vasc Anesth 1992;6:542-53.
    • (1992) J Cardiothorac Vasc Anesth , vol.6 , pp. 542-553
    • Dupuis, J.-Y.1    Bondy, R.2    Cattran, C.3    Nathan, H.J.4    Wynands, J.E.5
  • 25
    • 0029162301 scopus 로고
    • A pharmacokinetic and pharmacodynamic evaluation of milrinone in adults undergoing cardiac surgery
    • Butterworth IV JF, Hines RL, Royster RL, James RL. A pharmacokinetic and pharmacodynamic evaluation of milrinone in adults undergoing cardiac surgery. Anesth Analg 1995;81:783-92.
    • (1995) Anesth Analg , vol.81 , pp. 783-792
    • Butterworth IV, J.F.1    Hines, R.L.2    Royster, R.L.3    James, R.L.4
  • 26
    • 0031976338 scopus 로고    scopus 로고
    • Effects of a new calcium sensitizer, levosimendan, on haemodynamics, coronary blood flow and myocardial substrate utilization early after coronary artery bypass grafting
    • Lilleberg J, Nieminen MS, Akkila J, et al. Effects of a new calcium sensitizer, levosimendan, on haemodynamics, coronary blood flow and myocardial substrate utilization early after coronary artery bypass grafting. Eur Heart J 1998;19:660-8.
    • (1998) Eur Heart J , vol.19 , pp. 660-668
    • Lilleberg, J.1    Nieminen, M.S.2    Akkila, J.3
  • 27
    • 0029808961 scopus 로고    scopus 로고
    • Pharmacology of levosimendan: A new myofilament calcium sensitizer
    • Pagel PS, Haikala H, Pentikainen PJ, et al. Pharmacology of levosimendan: a new myofilament calcium sensitizer. Cardiovasc Drug Rev 1996;14:286-316.
    • (1996) Cardiovasc Drug Rev , vol.14 , pp. 286-316
    • Pagel, P.S.1    Haikala, H.2    Pentikainen, P.J.3
  • 29
    • 0027377452 scopus 로고
    • Amrinone in cardiac surgical patients with left-ventricular dysfunction: A prospective, randomized placebo-controlled trial
    • Butterworth JF IV, Royster RL, Prielipp RC, Lawless ST, Wallenhaupt SL. Amrinone in cardiac surgical patients with left-ventricular dysfunction: a prospective, randomized placebo-controlled trial. Chest 1993;104:1660-7.
    • (1993) Chest , vol.104 , pp. 1660-1667
    • Butterworth IV, J.F.1    Royster, R.L.2    Prielipp, R.C.3    Lawless, S.T.4    Wallenhaupt, S.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.