Degradation of cardiac troponin I in serum complicates comparisons of cardiac troponin I assays

Clinical Chemistry

Volumn 45, Issue 7, 1999, Pages 1018-1025

  Shi, Qinwei ^a   Ling, Mingfu ^a   Zhang, Xiaochen ^a   Zhang, Minyuan ^a   Kadijevic, Lilly ^a   Liu, Shigui ^a   Laurino, Joseph P ^a  

^a Spectral Diagnostics Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT PROTEIN; TROPONIN I;

ARTICLE; CONTROLLED STUDY; GENETIC ENGINEERING; HEART; HUMAN; IMMUNOASSAY; IMMUNOBLOTTING; PROTEIN DEGRADATION;

EID: 0032771644     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/45.7.1018     Document Type: Article

References (31)

1. Wilkinson JM, Grand RJ. Comparison of amino acid sequence of troponin I from different striated muscles. Nature 1978;271:31-5.
2. MacGeoch C, Barton PJ, Vallins WJ, Bhavsar P, Spurr NK. The human Cardiac troponin I locus: assignment to chromosome 19p13.2-19q13.2. Hum Genet 1991;88:101-4.
3. Bodor GS, Porterfield D, Voss EM, Smith S, Apple FS. Cardiac troponin-I is not expressed in fetal and healthy or diseased adult human skeletal muscle tissue. Clin Chem 1995;41:1710-5.
4. Larue C, Calzolari C, Bertinchant JP, Leclercq F, Grolleau R, Pau B. Cardiac-specific immunoenzymometric assay of troponin I in the early phase of acute myocardial infarction. Clin Chem 1993;39:972-9.
5. D'Costa M, Fleming E, Patterson MC. Cardiac troponin I for the diagnosis of acute myocardial infarction in the emergency department. Am J Clin Pathol 1997;108:550-5.
6. Hamm CW, Goldmann BU, Heeschen C, Kreymann O, Berger J, Meinertz T. Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med 1997;337:1648-53.
7. Antman EM, Tanasijevic MJ, Thompson B, Schactman M, McCabe CH, Cannon CP, et al. Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med 1996;335:1342-9.
8. Quillard M, Koning R, Andres H, Cauliez B, Hue G, Letac B, et al. Determination of cardiac troponin I on Stratus analyzer: prospective evaluation in unstable angina. Ann Biol Clin 1996;54:359-63.
9. Christenson RH, Apple FS, Morgan DL, Alonsozana GL, Mascotti K, Olson M, et al. Cardiac troponin I measurement with the ACCESS® Immunoassay system: analytical and clinical performance characteristics. Clin Chem 1998;44:52-60.
10. Panteghini M, Bonora R, Pagani F. Rapid and specific immunoassay for cardiac troponin I in the diagnosis of myocardial damage. Int J Clin Lab Res 1997;27:60-4.
11. Wu AHB, Feng YJ, Moore R, Apple FS, McPherson PH, Buechler KF, et al. Characterization of cardiac troponin subunit release into serum after acute myocardial infarction and comparison of assays for troponin T and I. Clin Chem 1998;44:1198-208.
12. Westfall MV, Solaro RJ. Alterations in myofibrillar function and protein profiles after complete global ischemia in rat hearts. Circ Res 1992;70:302-13.
13. Gao WD, Atar D, Liu Y, Perez NG, Murphy AM, Marban E. Role of troponin I proteolysis in the pathogenesis of stunned myocardium. Circ Res 1997;80:393-9.
14. Van Eyk JE, Powers F, Law W, Larue C, Hodges RS, Solaro RJ. Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts, identification of degradation products and effects on pCa-force relation. Circ Res 1998;82:261-71.
15. Hu XY, Shi QW, Yang T, Jackowski G. Specific replacement of consecutive AGG codons results in high-level expression of human cardiac troponin T in Escherichia coli. Protein Expr Purif 1996;7:289-93.
16. Vallins WJ, Brand NJ, Dabhade N, Butler-Browne G, Yacoub MH, Barton PJR. Molecular cloning of human cardiac troponin I using polymerase chain reaction. FEBS Lett 1990;270:57-61.
17. Gahlman R, Wade R, Gunning P, Kedes L. Differential expression of slow and fast skeletal muscle troponin C. J Mol Biol 1988;201:379-91.
18. 2+ dependence of the distance between Cys-98 of troponin C and Cys-133 of troponin I in the ternary troponin complex. Resonance energy transfer measurements. Biochemistry 1989;28:5902-8.
19. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;2:248-54.
20. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
21. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 1979;76:4350-4.
22. Kimura A, Harada H, Park JE, Nishi H, Satoh M, Takahashi M, et al. Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy. Nat Ganet 1997;16:379-82.
23. Ardelt P, Dorka P, Jaquet K, Heilmeyer LMG Jr, Kortke H, Korfer R, et al. Microanalysis and distribution of cardiac troponin I phospho species in heart areas. Biol Chem 1998;379:341-7.
24. Katrukha A, Bereznikova A, Filatov A, Esakova T, Kolosova O, Pettersson K, et al. Degradation of cardiac troponin I: implication for reliable immunodetection. Clin Chem 1998;44:2433-40.
25. Morjana N. Degradation of human cardiac troponin I after myocardial infarction. Biotechnol Appl Biochem 1998;28:105-11.
26. Adams JE, Schechtman KB, Landt Y, Ladenson JH, Jaffe AS. Comparable detection of acute myocardial infarction by creatine kinase MB isoenzyme and cardiac troponin I. Clin Chem 1994;40:1291-5.
27. Jaffe AS, Landt Y, Parvin CA, Abendschein DR, Geltman EM, Ladenson JH. Comparative sensitivity of cardiac troponin I and lactate dehydrogenase isoenzymes for diagnosing acute myocardial infarction. Clin Chem 1996;11:1770-6.
28. Katrukha AG, Bereznikova AV, Esakova TV, Pettersson K, Lovgren T, Severina ME, et al. Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex. Clin Chem 1997;43:1379-85.
29. Giuliani I, Bertinchant JP, Granier C, Laprade M, Chocron S, Toubin G, et al. Determination of cardiac troponin I forms in the blood of patients with acute myocardial infarction and patients receiving crystalloid or cold blood cardioplegia. Clin Chem 1999;45:213-22.
30. Saijo Y, Takeda S, Scherer A, Kobayashi T, Maeda Y, Teniguchi H, et al. Production, crystallization, and preliminary x-ray analysis of rabbit skeletal muscle troponin complex consisting of troponin C and fragment (1-47) of troponin I. Protein Sci 1997;6:916-8.
31. Krudy GA, Kleerekoper Q, Guo XD, Howarth JW, Solaro RJ, Rosevear PR. NMR studies delineating spatial relationships within the cardiac troponin I-troponin C complex. J Biol Chem 1994;269:23731-5.