Identification of two transcripts of canine, feline, and porcine interleukin-1 alpha

Gene

Volumn 236, Issue 2, 1999, Pages 273-280

  Straubinger, Alex F ^a   Viveiros, Maria M ^a   Straubinger, Reinhard K ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Alternative splicing; Cytokine; Dog; Lyme arthritis; Macrophage; mRNA

Indexed keywords

CYTOKINE; DNA FRAGMENT; INTERLEUKIN 1ALPHA; MESSENGER RNA;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BORRELIA BURGDORFERI; CAT; CONTROLLED STUDY; COW; DNA SEQUENCE; DOG; HORSE; HUMAN; LUNG ALVEOLUS MACROPHAGE; LYME DISEASE; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SOUTHERN BLOTTING; SWINE; SYNOVIUM;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CATS; CATTLE; DOGS; HORSES; INTERLEUKIN-1; INTERLEUKIN-8; LYME DISEASE; MACROPHAGES; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, NUCLEIC ACID; SWINE; SYNOVIAL MEMBRANE; UP-REGULATION;

ANIMALIA; BORRELIA; BORRELIA BURGDORFERI; BOVINAE; CANIS FAMILIARIS; EQUIDAE; EQUUS CABALLUS; EUKARYOTA; FELIDAE; FELIS CATUS; MAMMALIA; MURINAE; SUIDAE; SUS SCROFA;

EID: 0032770480     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00274-7     Document Type: Article

References (26)

1. Alms W.J., Atamas S.P., Yurovsky V.V., White B. Generation of a variant of human interleukin-4 by alternative splicing. Mol. Immunol. 33:1996;361-370.
2. Anderson J.F., Magnarelli L.A. Avian and mammalian hosts for spirochete infected ticks and insects in a Lyme disease focus in Connecticut. Yale J. Biol. Med. 57:1984;627-641.
3. Appel M.J.G., Allen S., Jacobson R.H., Lauderdale T.L., Chang Y.F., Shin S.J., Thomford J.W., Todhunter R.J., Summers B.A. Experimental Lyme disease in dogs produces arthritis and persistent infection. J. Infect. Dis. 167:1993;651-664.
4. Atamas S.P., Choi J., Yurovsky V.V., White B. An alternative splice variant of human IL-4, IL-4-delta-2, inhibits IL-4 stimulated T cell proliferation. J. Immunol. 156:1996;435-441.
5. DiGiovine F.S., Duff G.W. Interleukin 1: the first interleukin. Immunol. Today. 11:1990;13-20.
6. Dinarello C.A. Biologic basis for interleukin-1 in disease. Blood. 87:1996;2095-2147.
7. Eissa N.T., Strauss A.J., Haggerty C.M., Choo E.K., Chu S.C., Moss J. Alternative splicing of human inducible nitric-oxide synthase mRNA: Tissue-specific regulation and induction by cytokines. J. Biol. Chem. 271:1996;27184-27187.
8. Furutani Y. Molecular studies on interleukin-1α Eur. Cytokine Network. 5:1994;533-538.
9. Kaplanski G., Farnarier C., Kaplanski S., Porat R., Shapiro L., Bongrand P., Dinarello C.A. Interleukin-1 induces interleukin-8 from endothelial cells by juxtacrine mechanisms. Blood. 84:1994;4242-4248.
10. Kato H., Youn H., Ohashi T., Watari T., Goitsuka R., Tsujimoto H., Hasegawa A. Identification of an alternatively spliced transcript of equine interleukin-1β Gene. 177:1996;11-16.
11. Kobayashi Y., Oppenheim J.J., Matsushima K. Human pre-interleukin-1α and β: Structural features revealed by limited proteolysis. Chem. Pharmaceut. Bull. 39:1991;1513-1517.
12. Kobayashi Y., Yamamoto K., Saido T., Kawasaki H., Oppenheim J.J., Matsushima K. Identification of calcium-activated neutral protease as a processing enzyme of human interleukin-1 alpha. Proc. Natl. Acad. Sci. 87:1990;5548-5552.
13. Kurt-Jones E.A., Beller D.I., Mizel S.B., Unanue E.R. Identification of a membrane-associated interleukin-1 in macrophages. Proc. Natl. Acad. Sci. 82:1985;1204-1208.
14. Levy S.A., Barthold S.W., Daubach D.M., Wasmoen T.L. Canine Lyme borreliosis. Compend. Cont. Educ. Pract. Vet. 15:1993;833-848.
15. Liu C., Hart R.P., Liu X.J., Clevenger W., Maki R.A., DeSouza E.B. Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA. J. Biol. Chem. 271:1996;20965-20972.
16. Meazza R., Verdiani S., Biassoni R., Coppolecchia M., Gaggero Al., Orengo A.M., Colombo M.P., Azzarone B., Ferrini S. Identification of novel interleukin-15 (IL-15) transcript isoform generated by alternative splicing in human small cell lung cancer cell lines. Oncogene. 12:1996;2187-2192.
17. Mosley B., Urdal D.L., Prickett K.S., Larsen A., Cosman D., Conlon P.J., Gillis S., Dower S.K. The interleukin-1 receptor binds the human interleukin-1α precursor but not the interleukin-1α precursor. J. Biol. Chem. 262:1987;2941-2944.
18. Niki Y., Yamada H., Kikuchi T., Takaishi H., Fujikawa K., Tada N. Membrane-associated IL-1 contributes to chronic synovitis in human IL-1alpha transgenic mice. Arthritis Rheum. 41:1998;212.
19. Steere A.C. Lyme disease. N. Engl. J. Med. 321:1989;586-596.
20. Stevenson F.T., Bursten S.L., Fanton C., Locksley R.M., Lovett D.M. The 31-kDa precursor of interleukin-1α is myristolated on specific lysines within the 16-kDa N-terminal propiece. Proc. Natl. Acad. Sci. 90:1993;7245-7249.
21. Straubinger R.K., Straubinger A.F., Härter L., Jacobson R.H., Chang Y.-F., Summers B.A., Erb H.N., Appel M.J.G. Borrelia burgdorferi migrates into joint capsules and causes an up-regulation of interleukin-8 in synovial membranes of dogs experimentally infected with ticks. Infect. Immun. 65:1997;1273-1285.
22. Straubinger R.K., Straubinger A.F., Summers B.A., Erb H.N., Härter L., Appel M.J.G. Borrelia burgdorferi induces the production and release of proinflammatory cytokines in canine synovial explant cultures. Infect. Immun. 66:1998;247-258.
23. Tsytsikov V.N., Yurovsky V.V., Atamas S.P., Alms W.J., White B. Identification and characterization of two alternative splice variants of human interleukin-2. J. Biol. Chem. 271:1996;23055-23060.
24. Watanabe N., Kobayashi Y. Selective release of a processed form of interleukin-1α Cytokine. 6:1994;597-601.
25. Weissbach L., Tran K., Colquhoun S.A., Champliaud M.F., Towle C.A. Detection of an interleukin-1 intracellular receptor antagonist mRNA variant. Biochem. Biophys. Res. Commun. 244:1998;91-95.
26. Wessendorf J.H.M., Garfinkel S., Zhan X., Brown S., Maciag T. Identification of a nuclear localization sequence within the structure of the human interleukin-1α precursor. J. Biol. Chem. 268:1993;22100-22104.