Degradation and protein release properties of microspheres prepared from biodegradable poly(lactide-co-glycolide) and ABA triblock copolymers: influence of buffer media on polymer erosion and bovine serum albumin release

Journal of Controlled Release

Volumn 60, Issue 2-3, 1999, Pages 297-309

  Bittner, Beate ^a   Witt, Christian ^a   Mäder, Karsten ^a   Kissel, Thomas ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

ABA triblock copolymers; Biodegradable microspheres; Poly(lactide co glycolide); Polymer degradation mechanism; Protein release

Indexed keywords

BOVINE SERUM ALBUMIN; COPOLYMER; MACROGOL; MICROSPHERE; POLYGLACTIN; POLYGLYCOLIC ACID; POLYLYSINE;

ARTICLE; DRUG DEGRADATION; DRUG RELEASE; DRUG SYNTHESIS; ELECTRON SPIN RESONANCE; EROSION; IN VITRO STUDY; IONIC STRENGTH; MOLECULAR WEIGHT; PARTICLE SIZE; PH; PRIORITY JOURNAL;

ANIMALS; BIODEGRADATION, ENVIRONMENTAL; BUFFERS; CATTLE; DELAYED-ACTION PREPARATIONS; ELECTRON SPIN RESONANCE SPECTROSCOPY; EMULSIONS; HYDROGEN-ION CONCENTRATION; MICROSPHERES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; POLYMERS; SERUM ALBUMIN, BOVINE; TIME FACTORS;

EID: 0032769902     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(99)00085-1     Document Type: Article

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