Peptide binding affinity and pH variation establish functional thresholds for activation of HLA-DQ-restricted T cell recognition

Human Immunology

Volumn 60, Issue 7, 1999, Pages 619-626

  Kwok, William W ^a,b   Reijonen, Helena ^a   Falk, Ben A ^a   Koelle, David M ^b   Nepom, Gerald T ^a,b  

^a BENAROYA RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

DQ restricted T cell; DQA1*0301 DQB1*0302; HSV 2 VP16; IDDM; Peptide binding

Indexed keywords

HLA DQ ANTIGEN; PEPTIDE; VIRUS PROTEIN;

ACIDITY; ALKALINITY; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CLONE; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN BINDING; T LYMPHOCYTE; VIRION;

AMINO ACID SEQUENCE; ANTIGEN-PRESENTING CELLS; CELL LINE, TRANSFORMED; CELLS, CULTURED; HERPES SIMPLEX VIRUS PROTEIN VMW65; HLA-DQ ANTIGENS; HUMANS; HYDROGEN-ION CONCENTRATION; LYMPHOCYTE ACTIVATION; MOLECULAR SEQUENCE DATA; PEPTIDES; T-LYMPHOCYTES;

EID: 0032769763     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(99)00041-5     Document Type: Article

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