-
1
-
-
0019831499
-
The role of phospholipid and factor VIIIa in the activation of bovine factor X
-
van Dieijen G., Tans G., Rosing J., Hemker H.C. The role of phospholipid and factor VIIIa in the activation of bovine factor X. J Biol Chem. 256:1981;3433-3442.
-
(1981)
J Biol Chem
, vol.256
, pp. 3433-3442
-
-
Van Dieijen, G.1
Tans, G.2
Rosing, J.3
Hemker, H.C.4
-
2
-
-
0021677942
-
Structure of human factor VIII
-
Vehar G.A., Keyt B., Eaton D., Rodrigues H., O'Brien D.P., Rotblat F., Opperman H., Keck R., Wood W.I., Harkins R.N., Tuddenham E.G.D., Lawn R.M., Capon D.J. Structure of human factor VIII. Nature. 312:1984;337-340.
-
(1984)
Nature
, vol.312
, pp. 337-340
-
-
Vehar, G.A.1
Keyt, B.2
Eaton, D.3
Rodrigues, H.4
O'Brien, D.P.5
Rotblat, F.6
Opperman, H.7
Keck, R.8
Wood, W.I.9
Harkins, R.N.10
Tuddenham, E.G.D.11
Lawn, R.M.12
Capon, D.J.13
-
3
-
-
0022445266
-
The size of human factor VIII heterodimers and the effects produced by thrombin
-
Fay P.J., Anderson M.T., Chavin S.I., Marder V.J. The size of human factor VIII heterodimers and the effects produced by thrombin. Biochem Biophys Acta. 87:1986;268-278.
-
(1986)
Biochem Biophys Acta
, vol.87
, pp. 268-278
-
-
Fay, P.J.1
Anderson, M.T.2
Chavin, S.I.3
Marder, V.J.4
-
4
-
-
0023918416
-
Reconstition of human factor VIII from isolated subunits
-
Fay P.J. Reconstition of human factor VIII from isolated subunits. Arch Biochem Biophys. 262:1988;525-531.
-
(1988)
Arch Biochem Biophys
, vol.262
, pp. 525-531
-
-
Fay, P.J.1
-
5
-
-
0023864433
-
Generation of active coagulation factor VIII from isolated subunits
-
Nordfang O., Ezban M. Generation of active coagulation factor VIII from isolated subunits. J.Biol.Chem. 263:1988;1115-1118.
-
(1988)
J.Biol.Chem.
, vol.263
, pp. 1115-1118
-
-
Nordfang, O.1
Ezban, M.2
-
6
-
-
0025748557
-
The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII
-
Wise R.J., Dorner A.J., Krane M., Pittman D.D., Kaufman R.J. The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII. J Biol Chem. 266:1991;21948-21955.
-
(1991)
J Biol Chem.
, vol.266
, pp. 21948-21955
-
-
Wise, R.J.1
Dorner, A.J.2
Krane, M.3
Pittman, D.D.4
Kaufman, R.J.5
-
7
-
-
0025766610
-
Von Willebrand factor mediates protection of factor VIII from activated protein C-catalyzed inactivation
-
Fay P.J., Coumans J.-V., Walker F.J. von Willebrand factor mediates protection of factor VIII from activated protein C-catalyzed inactivation. J Biol Chem. 266:1991;2172-2177.
-
(1991)
J Biol Chem.
, vol.266
, pp. 2172-2177
-
-
Fay, P.J.1
Coumans, J.-V.2
Walker, F.J.3
-
8
-
-
0025991461
-
The effect of plasma von Willebrand factor on the binding of human factor VIII to thrombin-activated human platelets
-
Nesheim M., Pittman D.D., Giles A.R., Fass D.N., Wang J.H., Slonosky D., Kaufman R.I. The effect of plasma von Willebrand factor on the binding of human factor VIII to thrombin-activated human platelets. J Biol Chem. 266:1991;17815-17826.
-
(1991)
J Biol Chem
, vol.266
, pp. 17815-17826
-
-
Nesheim, M.1
Pittman, D.D.2
Giles, A.R.3
Fass, D.N.4
Wang, J.H.5
Slonosky, D.6
Kaufman, R.I.7
-
9
-
-
0028407120
-
Von Willebrand factor as a regulator of intrinsic factor X activation
-
Koppelman S.J., Koedam J.A., van Wijnen M., Stern D.M., Nawroth P.P., Sixma J.J., Bouma B.N. von Willebrand factor as a regulator of intrinsic factor X activation. J Lab Clin Med. 123:1994;585-593.
-
(1994)
J Lab Clin Med
, vol.123
, pp. 585-593
-
-
Koppelman, S.J.1
Koedam, J.A.2
Van Wijnen, M.3
Stern, D.M.4
Nawroth, P.P.5
Sixma, J.J.6
Bouma, B.N.7
-
10
-
-
0023217139
-
A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor
-
Foster P.A., Fulcher C.A., Marti T., Titani K., Zimmerman T.S. A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor. J Biol Chem. 262:1987;8443-8446.
-
(1987)
J Biol Chem
, vol.262
, pp. 8443-8446
-
-
Foster, P.A.1
Fulcher, C.A.2
Marti, T.3
Titani, K.4
Zimmerman, T.S.5
-
11
-
-
0024400371
-
A monoclonal antibody to von Willebrand factor (vWF) inhibits factor VIII binding. Localization of its antigenic determinant to a nonadecapeptide at the amino terminus of the mature vWF polypeptide
-
Bahou W.F., Ginsburg D., Sikkink R., Litwiller R., Fass D.N. A monoclonal antibody to von Willebrand factor (vWF) inhibits factor VIII binding. Localization of its antigenic determinant to a nonadecapeptide at the amino terminus of the mature vWF polypeptide. J Clin Invest. 84:1989;56-61.
-
(1989)
J Clin Invest
, vol.84
, pp. 56-61
-
-
Bahou, W.F.1
Ginsburg, D.2
Sikkink, R.3
Litwiller, R.4
Fass, D.N.5
-
12
-
-
0028229744
-
Fine epitope mapping of monoclonal antibodies to NH2-terminal part of von Willebrand factor (vWF) by using recombinant and synthetic peptides: Interest for the localization of the factor VIII binding domain
-
Jorieux S., Gaucher C., Pietu G., Cherel C., Meyer D., Mazurier C. Fine epitope mapping of monoclonal antibodies to NH2-terminal part of von Willebrand factor (vWF) by using recombinant and synthetic peptides. Interest for the localization of the factor VIII binding domain Br J Haematol. 87:1994;113-118.
-
(1994)
Br J Haematol
, vol.87
, pp. 113-118
-
-
Jorieux, S.1
Gaucher, C.2
Pietu, G.3
Cherel, C.4
Meyer, D.5
Mazurier, C.6
-
13
-
-
0023624477
-
Stoichiometry of the porcine factor VIII-von Willebrand factor association
-
Lollar P., Parker C.G. Stoichiometry of the porcine factor VIII-von Willebrand factor association. J Biol Chem. 262:1987;17572-17576.
-
(1987)
J Biol Chem
, vol.262
, pp. 17572-17576
-
-
Lollar, P.1
Parker, C.G.2
-
14
-
-
0029035099
-
The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor
-
Vlot A.J., Koppelman S.J., van den Berg M.H., Bouma B.N., Sixma J.J. The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor. Blood. 85:1995;3150-3157.
-
(1995)
Blood
, vol.85
, pp. 3150-3157
-
-
Vlot, A.J.1
Koppelman, S.J.2
Van Den Berg, M.H.3
Bouma, B.N.4
Sixma, J.J.5
-
15
-
-
0023677854
-
Association of the factor VIII light chain with von Willebrand factor
-
Lollar P., Hill-Eubanks D.C., Parker C.G. Association of the factor VIII light chain with von Willebrand factor. J Biol Chem. 263:1988;10451-10455.
-
(1988)
J Biol Chem
, vol.263
, pp. 10451-10455
-
-
Lollar, P.1
Hill-Eubanks, D.C.2
Parker, C.G.3
-
16
-
-
0023922071
-
An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor
-
Foster P.A., Fulcher C.A., Houghten R.A., Zimmerman T.S. An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor. J Biol Chem. 263:1988;5230-5234.
-
(1988)
J Biol Chem
, vol.263
, pp. 5230-5234
-
-
Foster, P.A.1
Fulcher, C.A.2
Houghten, R.A.3
Zimmerman, T.S.4
-
17
-
-
0030800963
-
The acidic region of the light chain and the C2 domain together form a high affinity binding site for von Willebrand factor
-
Saenko E.L., Scandella D. The acidic region of the light chain and the C2 domain together form a high affinity binding site for von Willebrand factor. J Biol Chem. 272:1997;18007-18014.
-
(1997)
J Biol Chem
, vol.272
, pp. 18007-18014
-
-
Saenko, E.L.1
Scandella, D.2
-
18
-
-
0028289949
-
A role for the C2 domain of factor VIII in binding to von Willebrand factor
-
Saenko E.L., Shima M., Rajalakshmi K.J., Scandella D. A role for the C2 domain of factor VIII in binding to von Willebrand factor. J Biol Chem. 269:1994;11601-11605.
-
(1994)
J Biol Chem
, vol.269
, pp. 11601-11605
-
-
Saenko, E.L.1
Shima, M.2
Rajalakshmi, K.J.3
Scandella, D.4
-
19
-
-
0029032377
-
A mechanism for inhibition of factor VIII binding to phospholipid by von Willebrand factor
-
Saenko E.L., Scandella D. A mechanism for inhibition of factor VIII binding to phospholipid by von Willebrand factor. J Biol Chem. 270:1995;13826-13833.
-
(1995)
J Biol Chem
, vol.270
, pp. 13826-13833
-
-
Saenko, E.L.1
Scandella, D.2
-
20
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:1976;248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
21
-
-
0023853342
-
Molecular characterization of commercial porcine factor VIII concentrate
-
Lollar P., Parker C.G., Tracy R.P. Molecular characterization of commercial porcine factor VIII concentrate. Blood. 71:1988;137-143.
-
(1988)
Blood
, vol.71
, pp. 137-143
-
-
Lollar, P.1
Parker, C.G.2
Tracy, R.P.3
-
22
-
-
0022475523
-
Human von Willebrand factor: A multivalent protein composed of identical subunits
-
Chopek M.W., Girma J.-P., Fujikawa K., Davie E.W., Titani K. Human von Willebrand factor. A multivalent protein composed of identical subunits Biochemistry. 25:1986;3146-3155.
-
(1986)
Biochemistry
, vol.25
, pp. 3146-3155
-
-
Chopek, M.W.1
Girma, J.-P.2
Fujikawa, K.3
Davie, E.W.4
Titani, K.5
-
23
-
-
0022547632
-
Limited proteolysis of human von Willebrand factor by Staphylococcus aureus V-8 protease: Isolation and partial characterization of platelet-binding domain
-
Girma J.-P., Chopek M.W., Titani K., Davie E.W. Limited proteolysis of human von Willebrand factor by Staphylococcus aureus V-8 protease. Isolation and partial characterization of platelet-binding domain Biochemistry. 25:1986;3156-3163.
-
(1986)
Biochemistry
, vol.25
, pp. 3156-3163
-
-
Girma, J.-P.1
Chopek, M.W.2
Titani, K.3
Davie, E.W.4
-
24
-
-
0023547917
-
Identification of disulfide-bridged substractures within human von Willebrand factor
-
Marti T., Rosselet S.J., Titani K., Walsh K.A. Identification of disulfide-bridged substractures within human von Willebrand factor. Biochemistry. 26:1987;8099-8109.
-
(1987)
Biochemistry
, vol.26
, pp. 8099-8109
-
-
Marti, T.1
Rosselet, S.J.2
Titani, K.3
Walsh, K.A.4
-
26
-
-
0028933042
-
Cleavage of factor VIII light chain is required for maximal generation of factor VIIIa activity
-
Regan L.M., Fay P.J. Cleavage of factor VIII light chain is required for maximal generation of factor VIIIa activity. J Biol Chem. 270:1995;8546-8552.
-
(1995)
J Biol Chem
, vol.270
, pp. 8546-8552
-
-
Regan, L.M.1
Fay, P.J.2
-
27
-
-
0002086499
-
-
editors. Orlando, FL: Grune & Startton, Inc.;
-
Bowie EJW, Owen CA. Ratnoff OD, Forbes CD, editors. Disorders of hemostasis. Orlando, FL: Grune & Startton, Inc.; 1984. p. 43-72.
-
(1984)
Disorders of Hemostasis
, pp. 43-72
-
-
Bowie, E.J.W.1
Owen, C.A.2
Ratnoff, O.D.3
Forbes, C.D.4
-
28
-
-
0032510718
-
Effects of copper on the structure and function of factor VIII subunits: Evidence for an auxiliary role for copper ions in cofactor activity
-
Sudhakar K., Fay P.J. Effects of copper on the structure and function of factor VIII subunits. Evidence for an auxiliary role for copper ions in cofactor activity Biochemistry. 37:1998;6874-6882.
-
(1998)
Biochemistry
, vol.37
, pp. 6874-6882
-
-
Sudhakar, K.1
Fay, P.J.2
-
29
-
-
0029861521
-
Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition
-
Saenko E.L., Shima M., Gilbert G.E., Scandella D. Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition. J Biol Chem. 271:1996;27424-27431.
-
(1996)
J Biol Chem
, vol.271
, pp. 27424-27431
-
-
Saenko, E.L.1
Shima, M.2
Gilbert, G.E.3
Scandella, D.4
-
30
-
-
0025923490
-
Human factor VIIIa subunit structure. Reconstitution of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit
-
Fay P.J., Haidaris P.J., Smudzin T.M. Human factor VIIIa subunit structure. Reconstitution of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit. J Biol Chem. 266:1991;8957-8962.
-
(1991)
J Biol Chem
, vol.266
, pp. 8957-8962
-
-
Fay, P.J.1
Haidaris, P.J.2
Smudzin, T.M.3
-
31
-
-
0020015138
-
Immunoradiometric assays for factor VIII antigens: Coagulant protein (antihemophilic factor) and factor VIII-related protein (von Willebrand factor)
-
Hoyer L.W., Trabold N.C. Immunoradiometric assays for factor VIII antigens. Coagulant protein (antihemophilic factor) and factor VIII-related protein (von Willebrand factor) Methods Enzymol. 84:1982;51-60.
-
(1982)
Methods Enzymol
, vol.84
, pp. 51-60
-
-
Hoyer, L.W.1
Trabold, N.C.2
-
32
-
-
0022457087
-
Amino acid sequence of human von Willebrand factor
-
Titani K., Kumar S., Takio K., Ericsson L.H., Wade R.D., Ashida K., Walsh K.A., Chopek M.W., Dadler J.E., Fujikawa K. Amino acid sequence of human von Willebrand factor. Biochemistry. 25:1986;3171-3184.
-
(1986)
Biochemistry
, vol.25
, pp. 3171-3184
-
-
Titani, K.1
Kumar, S.2
Takio, K.3
Ericsson, L.H.4
Wade, R.D.5
Ashida, K.6
Walsh, K.A.7
Chopek, M.W.8
Dadler, J.E.9
Fujikawa, K.10
-
33
-
-
0025241898
-
Topography of the human factor VIII-von Willebrand factor complex
-
Fay P.J., Smudzin T.M. Topography of the human factor VIII-von Willebrand factor complex. J Biol Chem. 265:1990;6197-6202.
-
(1990)
J Biol Chem
, vol.265
, pp. 6197-6202
-
-
Fay, P.J.1
Smudzin, T.M.2
-
34
-
-
0025944815
-
Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction anlysis in surface plasmon resonance sensors
-
Johnsson B., Lofas S., Lindquist G. Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction anlysis in surface plasmon resonance sensors. Anal Biochem. 198:1991;268-277.
-
(1991)
Anal Biochem
, vol.198
, pp. 268-277
-
-
Johnsson, B.1
Lofas, S.2
Lindquist, G.3
-
35
-
-
0027293351
-
Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: Use of nonlinear least squares analysis methods
-
O'Shannessy D.J., Brigham-Burke M., Sonenson K.K., Hensley P., Brooks I. Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance. Use of nonlinear least squares analysis methods Anal Biochem. 212:1993;457-468.
-
(1993)
Anal Biochem
, vol.212
, pp. 457-468
-
-
O'Shannessy, D.J.1
Brigham-Burke, M.2
Sonenson, K.K.3
Hensley, P.4
Brooks, I.5
-
36
-
-
0028919216
-
The role of cleavage of the light chain at positions arg1689 or arg1721 in subunit interaction and activation of human blood coagulation factor VIII
-
Donath M.-J.S.H., Lenting P.J., van Mourik J.A., Mertens K. The role of cleavage of the light chain at positions arg1689 or arg1721 in subunit interaction and activation of human blood coagulation factor VIII. J Biol Chem. 270:1996;3648-3655.
-
(1996)
J Biol Chem
, vol.270
, pp. 3648-3655
-
-
Donath, M.-J.S.H.1
Lenting, P.J.2
Van Mourik, J.A.3
Mertens, K.4
-
37
-
-
0028358217
-
Copper-atom identification in the active and inactive forms of plasma derived fVIII and recombinant fVIII-deltaII
-
Bihoreau N., Pin S., de Kersabiec A.-M., Vidot F., Fontaine-Aupart M.-P. Copper-atom identification in the active and inactive forms of plasma derived fVIII and recombinant fVIII-deltaII. Eur J Biochem. 220:1994;41-48.
-
(1994)
Eur J Biochem
, vol.220
, pp. 41-48
-
-
Bihoreau, N.1
Pin, S.2
De Kersabiec, A.-M.3
Vidot, F.4
Fontaine-Aupart, M.-P.5
-
38
-
-
0030783138
-
Identification and functional requirement of Cu(I) and its ligands within coagulation factor VIII
-
Tagliavacca L., Moon N., Dunham W.R., Kaufman R.J. Identification and functional requirement of Cu(I) and its ligands within coagulation factor VIII. J Biol Chem. 272:1997;27428-27434.
-
(1997)
J Biol Chem
, vol.272
, pp. 27428-27434
-
-
Tagliavacca, L.1
Moon, N.2
Dunham, W.R.3
Kaufman, R.J.4
-
39
-
-
0031059825
-
Recombinant, B-domain deleted Factor VIII (r-VIII SQ): Pharmacokinetics and initial safety aspects in hemophilia A patients
-
Fijnvandraat K., Bertorp E., Ten Cate J.W., Johnsson H., Peters M., Savidge G., Tengborn L., Spira J., Stahl C. Recombinant, B-domain deleted Factor VIII (r-VIII SQ). Pharmacokinetics and initial safety aspects in hemophilia A patients Thromb Haemost. 77:1997;298-302.
-
(1997)
Thromb Haemost
, vol.77
, pp. 298-302
-
-
Fijnvandraat, K.1
Bertorp, E.2
Ten Cate, J.W.3
Johnsson, H.4
Peters, M.5
Savidge, G.6
Tengborn, L.7
Spira, J.8
Stahl, C.9
|