Mutational analysis of MAdCAM-1/α4β7 interactions reveals significant binding determinants in both the first and second immunoglobulin domains

Cell Adhesion and Communication

Volumn 7, Issue 3, 1999, Pages 167-181

  Green, Nancy ^a   Rosebrook, Josh ^a   Cochran, Nancy ^a   Tan, Kemin ^b   Wang, Jia Huai ^b   Springer, Timothy A ^b   Briskin, Michael J ^a  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

FCS; ICAM 1; IgCAM; mAb; MAdCAM 1; MEM; VCAM 1

Indexed keywords

CELL ADHESION MOLECULE; IMMUNOGLOBULIN; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL MIGRATION; CHIMERA; CHO CELL; CONTROLLED STUDY; CRYSTAL STRUCTURE; LEUKOCYTE; LIGAND BINDING; LYMPHOCYTE; LYMPHOID TISSUE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; STEREOCHEMISTRY; VASCULAR ENDOTHELIUM;

EID: 0032762381     PISSN: 10615385     EISSN: None     Source Type: Journal    
DOI: 10.3109/15419069909010800     Document Type: Article

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